>9actn-a0a1g6re71 /F35/ Nocardioides lianchengensis Haloalkane dehalogenase HLD1 DnlA
MTHVRRTPDERFAALPGFPFEPRYVEVRADGVEPLRMHHLDEGPADGPVA
LLLHGQPTWSYLYRHVIPVLVAAGIRVVAPDNIGFGRSDKPTERTDYTLE
RHVAWTRGLVAALDLRDVTLVAQDWGGPIGLSVLAAEPDRFARVVAANTI
LHTADPALDGPLTWALHGTGDSRVVVEEALLDYLLHCVRAPELRAGDFVG
AATAHPLAPEVLAAYDAPFPDAEHTAGLRQMTALLPLTRRDAGARIGRRT
WRALESFDRPFVTCYSDSDPATRGWDRVFQERVPGARGRDHVTIAGAGHF
LQEDAGAELGRVVAEVVRTT
>9actn-g7h6v4 /F35/ Gordonia araii NBRC 100433 Haloalkane dehalogenase HLDIII dhmA DgarA
MTATLRPEWVDDELYPFTSRFVDVGGHTLHYLDEGTGPTLLFVHGNPTWS
FLYRDVIADLRSDFRCVAVDLPSFGLSSAAPGFSYLPDEHAAALAAFVEE
LDLREITLVCHDWGGPIGLTVAAGQPDRFTRFVIANTAGWPADDLSTWLV
SHAMGGPIGRLLIQRFNLFVNAMIPAGHRLRKPSDDEMAHYRNALDTRER
RTASAVFPRAITGSSDFLAAVEASLPGLSDRPALIVWGDADIAFGDKALR
RWEQVFDDHSTTIVAGGGHFVQSDAPEQFSRAIRDWARA
>9actn-l7fa57 /F35/ Streptomyces turgidiscabies Car8 Haloalkane_dehalogenase HLD1 DstA
MGQQHAAQHESEPTGESCFRTKTSEDLMTGMDVERTPDERFEGLADWPYE
PHYATVGEGLRMHYVDEGPSDGPVVVLAHGEPSWGYLYRKMIPGLVAAGR
RVLVPDLIGFGRSDKPVDRAAYTYESHIAWTGEWLDQLGLTDITLFGQDW
GGYIFNVHVGLTPDRFVAVVASNTGLTDPDFMASLTEEQFAQGFSAFLEW
RKMSEAPDLTASRAVASALGVSGDVLTEEEAAAYDAPFPSERYFAGARQL
PHLVTLETPETLAATLRSAWAGLEAFDKPFLTAFAEHDHISRPFEGIFQA
RVPGAKGQKHVTVPDAGHFLQEQQPDLLVEAILSLG
>9actn-m5a3u3 /F35/ Ilumatobacter coccineus YM16-304. Haloalkane dehalogenase
MHTLRTPDERFADLPDYPFAPNYVDVDDQDGGSLRVHYLDEGPADGPVVL
AMHGEPSWSYLYRKIIPLLVAGGARVIAPDLVGFGKSDKPTEKSDYTYER
HVAWMQAAIIDHLDLTDATFFGQDWGGLVGLRLVAENPDRFARVVIGNTG
LPTGEGSPSQAFLDWQKFSQESPVFPIGQILNGATITELTDAEIAAYDAP
FPDETYKEGARIFPSLVPTSTDDPAADANRAAWEVFRAWTKPFVCCFSDS
DPITGGGDKIFLKLVPGTEGQPHTTITNAHHFFQEDGAPQIAEVILDAIA
RG
>9acto-a0a098ye08 /F35/ Modestobacter sp. KNN45-2b. Haloalkane dehalogenase
MDALRTPEDRFTDLPEFPYEPRYVEVDDGDGGRLRMAVLVEGPDDGETVL
LLHGEPSWSFLYRRMIPVLTAARLRVVVPDPVGFGRSDKPTELTDYSYAR
HVAWLRQALLEELGLTDLTLVCQDWGGLLGLRLVAEHPERFTRVVVANTG
LPTGDHPMSEAFLAWQRAAAGMTDMQVGRIISNGTATEMASEVVAAYDAP
FPDSRYKAGARVFPSLVPTSPDDPAAAANRAAWGVLRSWEKPFLTAFSDS
DPITGGGDAVFQKLVPGAQGMPHTTLAGGGHFLQEDVGPQLAQVTVDLIA
ATPR
>9acto-d1xj60 /F35/ Streptomyces sp. ACTE Alpha/beta hydrolase fold protein
MPTLPVLGTTLHHRESGDPEGLPFVFLHGNPTSSHLWRNVLPAVAAPGRR
LLAPDLVGMGDSGKPDLAYSFDDHARHLDAWFDALGITEAVLVGHDWGGT
LAFDRAARLPDRVRGLAFTETIVKPLYGDEFPPAGRQLFELLRTPGVGEE
MVLEKSMFVEGLPATLATTLDPADLEVYRRAFPTPRSRRPVLEWARMMPL
DGEPADIVARIEHFDAWLATSPEVPKLLVAFEPGPGAMTDRGAVAWCEEN
IAGLEVSRNGLAGHHSPEDRPVELAAAINTWADHHGLTRA
>9acto-k6wlp4 /F35/ Gordonia rhizosphera NBRC 16068. Haloalkane dehalogenase
MSRILRTPDERFADLPDFPYAPHFIELGDVRMAVVDEGARDGEPVLLLHG
EPTWSYLYRKMIPPLVAAGLRVVVPDLIGFGQSDKPASIEDYSYQKHVDW
VFDAVRALELDQVTLFGQDWGSLIGLRIAAEHPQRFARVVIGNGFLPTAH
GSPSLAFLVWRTFARWSPVFPIGRLVDTGSLTKLTKAERAAYDAPFPDRT
YKAGARAFPRLVPLRADDPAVPANRAAWDALAAWDKPFLTLFGAKDPILG
RADAPLQRHIPGAAGQPHDRLRGGHFIQEDQGPELARRMIEFIGAGRR
>9alte-a3jb27 /F35/ 
Marinobacter sp. ELB17 psychrophilic bacterium paradoxically high thermostability haloalkane dehalogenase DmxA
MTTQKPADFPYPSHFADVLGSRMHYVEHGNGDPLLFLHGQPTWSYLWRKV
LPELEGKGRLIAVDLIGYGMSDKPDIPYDIDDHIRYLDGFIEALGLDRIT
IVCHDWGSFFGFHYAHRHPERIKGLAFMEAMLNPIPGYDAFDPQTRAFFQ
TLRSSQANAERMMMDENQFVENILPAMICRPLERQELDAYRAPWTDRQSR
RILCTFPQNLCIGKEPASVYRMQTAYIEWLGQTDLPKLLIHAEPGFLIPA
PAVDQYRQQLPNLETAFVGSGLHYIQEDQPQKIGQAIAQWMDRCGL
>9alte-a6ex60 /F35/ Marinobacter algicola DG893. Haloalkane dehalogenase
MNALRTPDKRFERLLDYPFAPHYVEVDGLRMHYVDEGPSDASPVLMMHGE
PSWSYLYRHMIPICAAAGHRVIAPDLIGFGKSDKPTDINAYSYQSHMDWM
QAFLEQTDLQNITLVCQDWGSLLGLRLAAENPDRFRAIVVGNGMLPTGDQ
PVPKAFQLWKNFALYSPWFPIARIINAGSFRTLGPDERRAYDAPFPDKKY
KAGARAFPKLVPVTPDNPASAANREAWKVLEQWKKPFLTTFSNGDPITRG
GDRYMQERIPGAKNQPHTTLTGGHFLQEDSPVEFAGAINALLARLDESDQ
T
>9alte-a6f419 /F35/ Marinobacter algicola DG893. Haloalkane dehalogenase
MRILRTDEARFAGLPDYPFTPHYLDVEPGLRMHYVDEGPSDASPVLMLHG
EPSWSYLYRHMIPLVADAGHRVLAPDLIGFGKSDKPADVGDYSYERHMAW
LSAWLKAQGLKNITLVCQNWGSLLGLRLAAEHPQLFRRIIVGNGMLPTGE
TPVPAVFSLWKTFAAHSPWFPVGRIVQLGTERALSKAEIAAYEAPFPSAE
FKAGARAFPKLVPVSGEDPSSDANKAAWRILETWKKPFITCFSSGDPITR
GGDRYMQRRIPGAHGQPHITLRGGHFLQEDSPDDFARIIIDACKSEMAA
>9alte-g6yut5 /F35/ Marinobacter manganoxydans; Marinobacter adhaerens Haloalkane dehalogenase
MALVSAPLLQHNPVDHSLTIMNNKASSMDFVRTPEKRFERLLDYPFEPHY
VEVDGLRMHYLDEGPANESPVLMMHGEPSWSYLYRHMIPICAAAGHRVIA
PDLIGFGKSDKPTSLDDYSYQQHMDWMQSFLDQLGLTNITLVCQDWGSLL
GLRLAAENPERFRAIVVGNGMLPTGDQTAPPAFKIWKNFALHSPWFPIAR
IINTGSFRKLGPDEMRAYDAPFPGKKYKAGARAFPRLVPMHPDDPASEAN
RNAWKVLERWEKPFLTTFSNGDPITRGGDAYMQKRIPGAKDQPHVTLKGG
HFLQEDSPVPFARAINDLLATLS
>9alte-k6xnl5 /F35/ Paraglaciecola agarilytica NO2 Haloalkane dehalogenase 1 dhmA1 DpaA
MTIKALRTPEERFSVLPAFPYQPNYVDDLGGYESLRMAYIDEGDKDSEYT
FLCLHGEPTWSYLYRKMIPVFTDAGHRVVAPDLFGFGRSDKPIEDSVYNF
EFHRNSLIQLIEHLDLKNIVLVCQDWGGGLGLTIPMDMQDRFKKLIVMNT
TISNGEPLAEAAVQWMAFNETISELPVAGLVACDAGAAVNVMDALAYDAP
FPNKNYKVGVKRFPQMIPTNADDDAVKYGLRAIEFWSNEWSGESFMAIGM
KDAVLGEAAMMQLKTVIKGCPEPMKIEEAGHFVQEYGVEVAEQALASFTM
I
>9alte-k6y704 /F35/ Glaciecola arctica BSs20135. Haloalkane dehalogenase
MQYLTTPEHCFEQITDFSYTPHFLQVDDNEGGLLKLHYVDEGPKDGDVVL
MLHGEPSWSYLYRKMIGPVVAAGYRVITPDLIGFGKSDKPTERSDYTFQR
HLDWVRQVIIQLDLKDITLVCQDWGGLLGLRLVAEHSDLFARVLAANTML
PTGDHSASEAFLNWQTFSQEVEVFPVAGIIKGATVSPLSPEVLAAYDAPF
PDETYKAGVRQFPLLVPTTPDNPASQDNRLAWESLQQFKKPFITAFSDSD
PVTAGGDKIMHKLIPGCEGQAHTTIEQGGHFLQEDKGEQLAEVLLTFMNA
NPL
>9alte-k7apw6 /F35/ Paraglaciecola psychrophila 170 Haloalkane dehalogenase HLD1 DppsA
MQFLTTPEHCFEQITDFCYPPQFLQVDDFEGGSLKLHYVDEGPRDANIVL
MLHGEPSWSYLYRKMINPLVSEGYRVIAPDLIGFGKSDKPTERSDYTYQR
HLDWVRQVIIQLDLKDITLVCQDWGGLLGLRLVAEHPDVFSRVLAANTML
PTGDHSPNEAFLNWQTFSQQVEVFPVAGVIKGATVTSLSPDVLDAYNAPF
PDETYKAGVRQFPLLVPTTPEDPASEANRQAWQILQQFNKPFITAFSDSD
PVTAGGDKIMQKLIPGCKGQAHTTIEKGGHFLQEDQGEKLAEVLLNFMNA
NPL
>9alte-m7crb9 /F35/ Marinobacter santoriniensis NKSG1. Haloalkane dehalogenase
MDFVRTPEKRFERLLDYPFAPNYLSMGEMRMHYVDEGPETANPILMMHGE
PSWSYLYRHMIPVCAAAGHRVIAPDLIGFGKSDKPTRVADYSYQAHMDWM
QAFIDGLELDNITLVCQDWGSLLGLRLAAENPDRFRAIVVGNGMLPTGDQ
AVPKAFRIWRAFALHSPWFPIARIINTGSFRTLGPDERRAYDAPFPNKTF
KAGARAFPALVPMSPNDPASEPNRKAWKVLEQWQKPFLTTFSNGDPITRG
GDHYMQQRVPGAANQPHTTLTGGHFLQEDSPVDFANAINDLLKRMETA
>9alte-n6w2r7 /F35/ Marinobacter nanhaiticus D15-8W. Haloalkane dehalogenase
MRILRTEEQRFAQLPDFPFEPHYLEVAPGLRMHYVDEGSPEAEPVLMLHG
EPSWSYLYRHMIPPVVEAGFRVLAPDLVGFGKSDKPASIEDYSYQSHMDW
LKAWIDELGLENITLVCQDWGSLLGLRMAAEHPERFSRIIVGNGMLPTGD
EKVPTVFHLWRGFAVYSPWFPISRIVQIGTARTLTDAECAAYDAPFPSSE
HKAGARAFPRLVPIRPDDPASEANRAAWVALEKWTKPFVTCFSNGDPVTR
GGDRYMQRRIPGAQGQPHTTLRGGHFLQEDAPEDFARIIIDACRH
>9alte-r8ayh5 /F35/ Marinobacter lipolyticus SM19. Haloalkane dehalogenase
MRILRTDEARFQSLPDYPFAPHYLDVEPGLRMHFVDEGPVAASPVVMLHG
EPSWSYLYRHMIPLVASAGHRVLAPDLIGFGKSDKPASVTDYSYQRHINW
LTHWLESLELTNITLVCQNWGSLLGLRLAAEKPHLFQRIIVGNGMLPTGE
TRIPPVFTMWKAFATHSPWFPVGRIVQLGTERALSRAELAAYEAPFPSPE
YKAGARAFPKLVPISPDDPASEPNRAAWKVLEKWRKPFITCFSSGDPITR
GGDRYMQRRIPGAYGQPHITLRGGHFLQEDSPEDFARIINDALKSVRAA
>9alte-r8b4s5 /F35/ Marinobacter lipolyticus SM19. Haloalkane dehalogenase
MNNKAQVMDFVRTPDARFDRLLDYPFDPHYVELDGLRMHYVDEGPSDANP
VLMMHGEPSWSYLYRHMIPVCAAAGHRVIAPDLIGFGKSDKPTSIGDYSY
QRHMEWMQLFIDKLELNNITLVCQDWGSLLGLRLAAENPDRFRAIVVGNG
MLPTGDQKTPPAFNLWKNFALHSPWFPIGRIINVGSFRKLSPDELRAYDA
PFPSKKYKAGARAFPRLVPVRPDDPASEANRKAWHVLECWEKPFLTTFSN
GDPITRGGDAYMQKRIPGAKDQPHVTLKGGHFLQEDSPVPFARAINTLIS
TLP
>9bact-q4pk85 /F35/ uncultured bacterium MedeBAC35C06 predicted haloalkane dehalogenase
MEILRTPDKYFENLKDYPFNPQYTNISAADGTEIRIHHIDEGPKDGPILL
AMHGQPVWSYLYARMIPYLTKAGIRVIAPDLVGYGKSDKPAAREDYSYQN
QVDWMGAWLTKNDFKNLTFFGQDWGGLIGLRMVAADPDRFIKIAMGNTGL
PYNPDVPQEVIDEIKAFRASNKKINFFTMAKNISKMDKSKHFATKFMYWQ
KFSWESKNMPIGFLNSMQMEDKLAKSKVKAYVHLLFQGLGLEKLSPFSTD
LIKAYEAPFPDPSYKMGPRAMPSQVPSIPDQSLEAQRKAREFFRTSNMPF
LSVFAGNDPVTNGIEKDVLKMAPNAISAPHIGGGHFFQWTKAELLSNVLI
KFIKE
>9bact-v5llk8 /F35/ uncultured bacterium. Haloalkane dehalogenase dhmA
MKVLRAPDEAFSGITDYPFAPHFLNVPSGDGTELRLHYVDEGASGADPIL
LMHGEPSWSYLYRRFVPALVAKGHRVVAPDLIGFGKSDKPAMRTDYTFER
HVAWMSDWLTQLDLANITLFCQDWGGLIGLRLVAAFPDRFARLVIGNTGL
PVGTGSSAGFDQWLAFSQNVPQFPVGTIVNMGTTRELTLAEIAAYDAPFP
DESYKEGARQFPTLVPITPEHASVAENLAAWKVLERFEKPVLTCFSDSDP
VSAGGEKAFINRVPGARGQAHRIIAEAGHFLQEDKPEELVALIDAFIGNR
RTS
>9bact-v5llz0 /F35/ uncultured bacterium. Haloalkane dehalogenase
MKVLRTPDEAFAGITGYPFAPHFLNVPGGDGTELRFHYVDEGASGADPIL
LMHGEPSWSYLYRKFVPALVSKGHRVIAPDLIGFGKSDKPAMRTDYTFER
HVAWMSDWLTRLDLANITLFCQDWGGLIGLRLVAAFPDRFARLVIGNTGL
PVGTGSSAGFDQWLAFSQNVPQFPVGTIVNMGTKRELTPAEIAAYDAPFP
DESYKEGARQFPTLVPITPEHASVAENLAAWKVLERFEKPVLTCFSDSDP
VSAGGEKAFINRVPGARGRPHRIIIEAGHFLQEDKPEELVALIHAFIGK
>9bact-v5ln96 /F35/ uncultured bacterium Haloalkane dehalogenase Cluster B eHLD-B
MLILRTPDDRFENLSDFDFAPHYTEIADGEGGTLRVHYLEEGPSDANPVL
LMHGEPSWSYLYRKMIPLLTTAGHRVIAPDLVGFGRSDKPSKRSDYTYAR
HVAWMSELLFDKLKLRHITFFGQDWGGLIGLRLVASAPERFDRVVVSNTG
LPTGDRKLSDAFLAWQNFSQTSETFPIGNIVNGGSATKLSPEVIAAYDAP
FPDDTYKEGARIFPSLVPTSRDDQAHHDNTLAWGVLNKFERPFLCAFGDS
DAVTKGGDAIFIRSVPGALNQNHTTIVGGGHFIQEDKPVELANIINTFIA
STT
>9burk-q4b2v7 /F35/ Polaromonas sp. JS666 binding region
DALRTPDAAFDDLPGYPWPPRYVSDLPALDGLRMHYLDEGEGGPGGLTYL
CLHGNPAWSYLYRKMIPVFLQAGHRVVAPDLIGFGKSDKPKKDSFHSFGV
HRQILLELVDRLDLQNVVLVVQDWGGLLGLTLPMVAPLRYKGLLVMNTML
ATSDVPLSPGFRAWREMCAKNPDFDVARLFARGNPQMSPDECAAYNAPFP
DKGHRAALRAFPLMVPESECADGAAISREAREFWQSRWTGQTLMAVGAQD
PVLGLPVMRALQGIIRGCDAPLVLEQAGHFVQEHGEPIARHAVGFFKR
>9caul-a0a1e4h0f2 /F35/ Phenylobacterium sp. SCN 70-31 Haloalkane dehalogenase HLD1 DphexA
MHETYAGVPFVRAPEPAFEGLPDYPWAPRYVEIDGLRMHYVEAGPSDGPV
ALLMHGMPTWSYLNRHLVAALAAAGYRCVAPDHIGFGRSDKVILDSWYSI
ARHVRAMAQLVAELDLRDITLFCQDWGGPIGLAQAAEFPERFARLVVMNT
WLHHDAFDYTPAVRRWNAGWHPGGFYAGNVPERLTIGWLMMAATGRTTRE
ALAAMAGGQPAPALSPSDDAVRRAYDAPFEGLGHAGHAGARRFPLSIPFD
NPEGGAAADQARHFETLLGWTRPIHFIWGAEDEVFPEAWGRAWAGRYPHA
TFDLLPDAGHFLQDTHGARIAELVLKHARA
>9chlr-d6tye6 /F35/ Ktedonobacter racemifer DSM 44963. Alpha/beta hydrolase fold protein
MKVLRTPDERFVNLPDYPFEPHYLEVDGLRIHYIDEGPREAAPVLLLHGE
PSWSYLYRKMVPLLSAAGHRVIAPDLVGFGRSDKPTRREDYTYKRHVDWM
HGVLNTLDLRQITLFCQDWGGLIGLRLAGEQPSRFARVVAANTFLPTGDQ
PPSEAFLHWQRMSQTFQGFQAGRVVKGGCVTPLAPEVVAAYDAPFPDESY
LTGALQFPLLVPTRPDDPASEANRAAWEVLRRWEKPFLTAFSDSDPITRG
GDAVLQALIPGAKGQPHTTITSSGHFLQEDKGPELARIINEFIAG
>9delt-a0a0m4d813 /F35/ Desulfuromonas soudanensis Haloalkane dehalogenase HLDIII DdsA
MESLYPFSSHYLELGDLNYHYLDEGTGDPVVMVHGNPSWSFYYRNLVLSL
RSDYRVVVPDHIGCGFSSKPDDSAYPYTLQQRVDDLDALLESLEIRERIT
LVLHDWGGMIGMAYACRHPERIARLVILNTAAFHLPAGKTFPLGLKICRD
TFLGTLLVRGFNAFARGAARVGCKRNPMTRELRDAYCSPYDSWKNRIATL
RFVQDIPLEPEDPGYDLITEVEQGLARFINRPMVICWGEMDFVFDSQFLT
EWTRRFPEAEVHAFADCGHYILEDAKDEVIPIIRDFLAAHPLAPRP
>9delt-a6g7b1 /F35/ Plesiocystis pacifica SIR-1 Haloalkane dehalogenase, putative
MEFVRTPDDRFADLPDFPYAPHYLEGLPGFEGLRMHYVDEGPRDAEHTFL
CLHGEPSWSFLYRKMLPVFTAAGGRVVAPDLFGFGRSDKPTDDAVYTFGF
HRRSLLAFLDALQLERVTLVCQDWGGILGLTLPVDRPQLVDRLIVMNTAL
AVGLSPGKGFESWRDFVANSPDLDVGKLMQRAIPGITDAEVAAYDAPFPG
PEFKAGVRRFPAIVPITPDMEGAEIGRQAMSFWSTQWSGPTFMAVGPQDP
VLGPEVMGMLRQAIGGCPEPMIVEAGGHFVQEHGEPIARAALAAFGQ
>9delt-a6ge89 /F35/ Plesiocystis pacifica SIR-1 Alpha/beta hydrolase
MYRTLIPSSLAALLSLGLACVSDPEDETESETSSETSPEISEAFPFERHE
LAVLDSTMTYVDEGEGPPIVLLHGQPASAYLWRNVIPHLSEDRRVIAVDL
IGFGGSGKPDIDYRIVDHAAYLEAFIDALALDEPLTLVVHDWGSFLGFDY
AMQHQEQIHAIVFMEAMLQPIPGYDFWDPDTAAFMEAIRTPGVGEAMIFE
QNMFIEALLPAMVMRELSPAEHDAYREPFLDPDTRAPMLSFPRELPVGGE
PADVHAMQVAYVDALRDSNVPKLHLYGTPGVLNTAADVEWAQANLPNITS
VEVGPGLHFLQEDHPHAIGEAIVDWLDGIDE
>9eury-a0a1i6hey7 /F35/ Halogeometricum limi Haloalkane dehalogenase HLDIII DhliA
MESESVASERSESPEDAHTDTSWVDRDAYPFETDCLRLTEGAVNYVDEGP
SDPAGTLLMLHGNPTWSFLYRHLVRGLSDRYRCVALDYLGFGLSERPEEF
SYRPEDHAVVVEEFVEALGLEDVILVVQDWGGPIGLSYAVDHPENVRALV
VMNTFAWPVDDDAHFRRFSALFGGALGRVLCERYDLFTRVVMPLAFGDRR
RFPASVREQYVAAHRGRDRTGTWMFPRRVVGSSGWLASLWNRRERIAHLP
TRIVWGMNDAAFRASELRTFEGWFEEASVVRLRGVGHYVQEEMGEDLVPY
VREFLESLGSEDETGYAD
>9eury-j3a357 /F35/ Halogranum salarium B-1 Haloalkane dehalogenase HLDIII DhsA
MSTPALDRPEWLDTDRYPFASNYVDCPEGRLHYVDEGDGDPIVFLHGNPT
WSFLYRHLVSGLSDSYRCIAPDYLGFGLSDKPEDFSYRPEDHARVVARFL
DELELTDVTFVVQDWGGPIGLDYATRHPENVRALVVLNTWMWPVEHDRRT
RLFSRAFDNPVGKRLVTRHNGFARWVMPLVYGDRSKLTPEIHRHYLEPLS
TSTERLGSWLFPREILGSSDWLRALWSRREAITDTPVCLLWGTQDPAFGP
AFLDRWQRLFPDAPTVAYDDAGHYLQEEKGPELATEIRSFLSSLEE
>9eury-m0il93 /F35/ Haloferax mucosum ATCC BAA-1512 Haloalkane dehalogenase HLDIII DhmuA
MTTVSSTERGDAVAALHRDAGWVDRSEFPFESRCLGLSDGAVHYVDEAPD
DGGQASLLMLHGNPTWSFLYRHLVRDLRDEYRCVALDYLGFGLSERPDEF
SYRPADHAAVVEEFIDELGLEDVVLVVQDWGGPIGLSYAIEHPENVSGLV
VMNTWLWPVDDDTHFSRFSKLLGGRVGRELCERYDLFTRLMPLAFADRSK
FSPSAREQYRAANDDDRTGTGVFPQSILGSSAWLSSLWKRRETIADIPAR
LIWGMDDPAFRPAELRTFEALFEDASTARLHGVGHYVQEEFGADLVPLVR
AFLDDLAG
>9gamm-a0ydx7 /F35/ marine gamma proteobacterium HTCC2143 Haloalkane dehalogenase
MKILRTPDHCFDGIKDYPFEPNYTVIQTQDGSNLRIHHIDEGPADGPILL
AMHGQPVWSYLYARMIPYLVKSGVRIIAPDLPGYGKSDKPASRADYSYQC
QVDWMNQWLVKNDFSQLTFFGQDWGGLIGLRMVVDNSHRFDRVAMGNTGL
PYNPDTPAHVVDDILAFRNGPEKLTLASMMKQVSTMDGFSNEDNPYAGPQ
KFAYWQKYTWDTQDVPAGIIASSQMETRNKLAMAAELLMGNLGLRNLSPF
RTDITRAYEAPFPSPAFKMAVRAMPSQVPSIPDRSLEAQKKAWEFFAEFD
KPFLCVGAGDDPVTNGFEKTFLEKVPGTKGQPHEMIGGGHFFQWARAEKL
SEILSRFVHDNQ
>9gamm-a0yei4 /F35/ marine gamma proteobacterium HTCC2143 Haloalkane dehalogenase
MISAEMPYEKKFQEVDGKKIAYVEAGEGDPIVLLHGNPTSSYLWRNVIPE
LVGKGRVIAPDLIGQGDSEKLPPSDGPDRYSFLVAYRYLEGLLDAIGANQ
RVTLVIHDWGSALGFYWAQQHSHNVRGIAYMEAIVCPVTWDDWPESARGI
FKGFRSDKGEDLVLQRNMFVEAVLPSSIIRQLGDAEMAHYRAAFSTPDDR
QPTLNWPRQIPISGEPAAMVDLVGSYAEWMHSNKDLPKLFVNADPGSILT
GKAREFCRSWPNQTEVTVKGTHFIQEDSPKEIGQAVAEWMDVLN
>9gamm-a0z6e4 /F35/ marine gamma proteobacterium HTCC2080 Haloalkane dehalogenase HLD1 DmgaA
MEFLRTPDDRFENLENFPYEPNYLSVPDGEGGQLRIHYVDTGPRDGRVVL
LMHGQPAWCYLYRSMIPLLVAKGFRVVAPDLVGFGRSDKPTERANYTYAN
HVAWMSDWLTQLGLEDITVFFQDWGSLIGLRLVTAFSERFNHVVLANGGL
PAGIIPEAFAKPLQEAYETLPVPEAHELGDRFRDTTGIPGFLYWRKFAAE
NPAIAQPGKSLMNDLMGAGLSQGEVDAYDAPFPDLSYAAGARQFPSLVPL
FHDEPEVPENKAAWKLLEQFDKPFLLAFADNDPVTQGGDKAFKERVPGCQ
GVEHRTISPAGHFLQQDQPEQCVQAILDVMAHGSS
>9gamm-a0z8c8 /F35/ marine gamma proteobacterium HTCC2080 Haloalkane dehalogenase
MSSEFRNLKKYKTINGKKMAYIEEGEGDPIVFLHGNPTSSYLWRKVMPPL
RGKGRLIAPDLIGMGDSQKLDNSGPDSYSFVEHKAYLFALLDELGVKENV
TLIIHDWGSALGFHWAEQNPEKVKAIAFMEAVVAVARNYDDLPKEFGQFV
QGVKSEAGEQMILEQNMFIEGILPMSIMRKLDDEEMAEYRRPFLNAGEDR
RPTLTWPRQIPVGGEPEDVTKVIADYGQYLATSPTPKLFVNADPGAMLRG
AARDLVRSWPNVSEVTVKGTHFIQEDSGEEIGQAIANWLAG
>9gamm-a0z514 /F35/ marine gamma proteobacterium HTCC2080 Alpha/beta hydrolase
MISANETFDGTWPFPPCFSTAAGFKQHYIDEGPRDGEVVVLLHGEPTWGY
LYRNMIPGLTAKYRVIVPDHMGFGKSETPQDKEYTLRTHVENLEALIEEL
RLTDITFVGQDWGGPITGAFTARNPKKVQRLFLMNTVLGFGGGKASGGKT
PWFQWIEKHANAGTLEGILGEMGSTVLSVMKIIGFQNSRDVSDTWIDAYS
APFPDRASCIGAISFPLDVHEGRFLPFVRETLEHGDLDALRAKPAMLISG
DKDFGIAKDHAISDFKGLFPSSPIVDVEGVGHFCQEDIPDTLVALIDSFI
QSNP
>9gamm-a6faz5 /F35/ Moritella sp. PE36 haloalkane dehalogenase HLDIII DmoxA
MLDKLFPFKRNYLDRNGQQYHYLNEGTGEPVVMVHGNPSWSFYYRNLVSA
LSTNYQCIVPDHIGCGLSDKPDDNDYDYTLTSRIDDLEALLEHLDIKENI
TLVVHDWGGMIGMGYAARHPERIKRLVILNTAAFHLPLSKAFPLPLWICR
NTVVGTFLVRGFNAFSSIASIVGVRRKAMSRDVRRAYVSPFNSWRNRIST
LRFVQDIPLKPEDRNYQLVTDIGDSLAKFSTVPTLICWGLKDFVFDKHFL
AQWKQRMPHAQVNEFDDCGHYILEDASDEVIELITDFMTDKR
>9gamm-b4wzn0 /F35/ Alcanivorax sp. DG881. Haloalkane dehalogenase
MADPGIYWYSLLTLRYQYRQGSAMDYLRTPDSRFERLLDYPFEPNYVDVG
GLRMHYVDEGPADGKPVLMLHGEPSWSYLYRHMIPICAAAGHRVIAPDLI
GFGKSDKPTDINAYSYQSHMDWVISLLDQLDLTDITLVCQDWGSLIGLRL
AAENESRFRAIVVGNGMLPTGDQQAPKAFHLWKNFAIYSPVLPISRILNT
ATFRKLGPDEIRAYDAPFPNRKYKAGARAFPKLVPVTPNDPASDANRAAW
KILEQWQKPFLTTFSNGDPITRGGDKYMQERVPGTQGQPHQTLVGGHFLQ
EDSPVQFAQAVNGLLRKFK
>9gamm-b7ry85 /F35/ marine gamma proteobacterium HTCC2148 Hydrolase, alpha/beta fold family, putative
MIAETMTYEKKFATVDGKRIAYVDVGSGDPIVLLHGNPTSSFLWRNVIPE
LEGSGRVIAPDLIGQGDSDKLPASDGVDRYSFEVAYHYLAGLLKELGAEE
KVTLVVHDWGSGLGFHWAMNNPDAIHGVAYMEAIVCPLNWDDWPEGARGI
FKGFRSDKGEDLILNRNMFVEAVLPTSVIRELTEKEMAAYREPFSSSDDR
QPTLNWPRHIPIDGEPAHMVDLVNAYGAFMAGSDIPKLFINADPGSILTG
PAREFCRQWPNQQEVTVNGLHFVQEDSPVEIGQAVANWLTNI
>9gamm-DtacA /F35/ Thalassomonas actiniarum Haloalkane dehalogenase HLD1 DtacA
NESQVTDAGIEYLVTPDACFDSLSGYDFAAHYVEIEGLRMHYVDEGPQDG
EVVLMLHGQPSWSYLYRKMIPILAQAGYRVIAPDHIGMGKSDKPVDVSIH
QFERHVAWTKAFINKLQLTDINLFVQDWGSVIGLRVAGNMPDKIARLTVA
NGDLVMHPPGNNPYTYPSFEIDESLGNVEEFFDGKSSDNIVGFQQWIDYA
ATAPNLKAGDVLQQLTTIDLSEEEVDAYNAPYPDIEYKAAIRSFPAMMTG
IEMQNLLAWQTLGAYHNPFMFNAGEHDQGLGSMEMQIKWTSHVPGAQGND
HRRFDAGHFIQDDVGEDLALHLLDFMQTT
>9gamm-l0wcp3 /F35/ Alcanivorax hongdengensis A-11-3. Haloalkane dehalogenase
MKVLRTPESRFSRLLDYPFEPHYVDVNGLRMHYVDEGPRDGKPVLMLHGE
PSWSYLYRHMIPVCAAAGHRVIAPDLIGFGKSDKPADRNAYNYQSHMDWL
QSLLDQLDLTDITLVCQDWGSLLGLRLAAENDARFRAIVVGNGMLPTGDQ
PVPRAFQLWKNFALYSPWFPIARIINSGTFRTLGPDERRAYDAPFPGKAY
KAGARMFPKLVPVTPDDPASDANRRAWQVLEQWRKPFLTTFSNGDPITRG
GDRYMQERIPGAAGQPHQTLTGGHFLQEDSPVAFANAINALLAGLDQAPS
GSGED
>9gamm-m4ukz1 /F35/ Psychromonas sp. CNPT3 hydrolase, Haloalkane_dehalogenase HLDIII
MNMHNNIDSLFPFQRNYLERNGQKYHYVNEGQGEPVVMIHGNPSWSFYYR
NLVQALRHENQCIVPDHIGCGFSSKPGDDDYDYCLKSRIDDLEALLDSLN
INENITLVVHDWGGMIGMGYAERHPDRIKRLVILNTSAFHLPSTKKLPLA
LYICRNTCLGTLLVRGLNAFSAVASYIGVKRKPMTKDVREAYVMPFNSWK
NRISTLRFIQDIPLSESDKSYALVSRISASVSQFKDTPTLICWGSQDFVF
DAHFLALWKEKMPHAQVNEFTDCGHYILEDASAEVIPLITEFIKQNK
>9gamm-q1mz21 /F35/ Oceanobacter sp. RED65 haloalkane dehalogenase (EC 3.8.1.5)
MHYVDEGPKDGKVILMMHGEPSWSYLYRFMIPICAAAGHRVIAPDLIGFG
KSDKPTKMEDYSYQQHMQWMQSFIDELNLKDITLVCQDWGSLLGLRLAAE
NASRFSAIAIGNGMLPTGEESKIPKAFKIWQNFARYSPWFPIARIVESGC
FKKLSKDERKAYDAPFPNKKFKAGARAFPRLVPTTPDNPATMANKAAWKV
LEKWDKPFLTLFSNGDPITRGLDKKIRERVPGCQGQPHQTLKGGHFLQED
AGFEMAQAVNELVARL
>9gamm-q1yua3 /F35/ marine gamma proteobacterium HTCC2207 haloalkane dehalogenase (EC 3.8.1.5)
MKILRTPDHCFDNIPDYPFEPHYTTIKTHDGSDLRIHHIDEGPKDGPVIL
CMHGQPVWSYLYARMIPHLVKAGIRVIAPDLPGYGKSDKPAAREDYSYQR
QVDWMNQWLVENDFTNLTFFGQDWGGLIGLRMVADNGDRFARVAIGNTGL
PYNPDVPPEVVEEIIAFRNSKKRLTLFSMMKELKKMNGLGGKRHDGARLF
AYWQKYTWQTPDVPAGIISSSQMETRSPLAVALELFIGAIGLRKISPFRT
QLSTIYEAPFPSPKYKMAVRAMPTQVPIMPDRSLEAQKKAWEFFEQFEKP
FLCVGAGNDPITNGFEKPWLAKVPGTKGQPHATIGGGHFFQWAKAEKLSG
ILADFIFKNSAD
>9gamm-u7g0y8 /F35/ Alcanivorax sp. P2S70. Haloalkane dehalogenase
MEYLRTPEDRFERLLDYPFAPHYVDVGGLRMHYVDEGPADAPPVLMLHGE
PTWSYLYRHMIPVCAAAGHRVIAPDLIGFGKSDKPTRIDDYSYQSHMDWL
LSLLDRLALTRITLVCQDWGSLLGLRLAAENPDRFRAIVVGNGMLPTGDQ
TVPTAFQLWKNFAIYSPVFPVSRIIDAASFRKLGPDEKRAYEAPFPNRKY
KAGARAFPKLVPVTPNDPATQANRAAWESLKQWRKPFLTTFSNGDPITRG
GDKYMQEQIPGAKGQPHQTLTGGHFLQEDSPVAFAQAVNQLIATQPSQD
>9myco-a0a024k1j2 /F35/ Mycobacterium triplex. Haloalkane dehalogenase
MDVLRTPDSRFENLEGYPFVANYIDVAASDTPPVRMHFLDEGPADGPPIV
LLHGEPTWSYLYRTMIPPLVESGNRVLAPDLIGFGRSDKPSRIEDYTYLR
HVEWVTAWFERLRLKEVTLFVQDWGSLIGLRIAAEQGERIARIVVANGFL
PAAQRKPSPGFLAWRAFARYSPVLPAGRIVAAGTVRRVPPKVRAGYDAPF
PDKTYQAGARAFPQLVPTSPDNPAIPANRAAWDALGRWEKPFLAIFGARD
PILGQADRPLIKHVPGAAGQPHARIRASHFIQEDSGPELAERVLAWQKPL
L
>9myco-a0a064c9r1 /F35/ Mycobacterium aromaticivorans JS19b1 = JCM 16368. Haloalkane dehalogenase
MDVLRTPDERFAALPDFPFEPRYVEVDSGDGGRLRMHYVDEGPSNGEVVL
LLHGEPSWSYLYRRMIPVLVDAGLRAVAIDLVGFGRSDKPASRDDYSYQA
HVDWMWAAIEQIGLADLTLVCQDWGGLIGLRLVGEHPDRFARVVAANTML
PTGDHHPGDAFLAWQKFSQEVPMFPAGQIVNGGSVSELSTETIAAYDAPF
PDDSYQAGARQFPMLVPTSPDDPAASANRAAWAALGRFEKPFLSAFSDSD
PITGAAEPVLREHVPGARRQSHVTIAAAGHFLQEDKGPELAEAVVAFVRA
NPRSE
>9myco-d5p7l8 /F35/ Mycobacterium parascrofulaceum ATCC BAA-614. Haloalkane dehalogenase
MHVLRTPDSRFENLEGYPFVANYLDVAASDTQPLRMHFLDEGPADGPPIV
LLHGEPTWSYLYRTMIQPLADAGNRVLAPDLIGFGRSDKPGRMEDYTYQR
HVDWVTSWFERLNLKDVTLFVQDWGSLIGLRIAAERGDRIARLVVANGFL
PTAERRTPPAFYAWRAFARYSPVLPAGRIVAAGTVRRVSARVRAGYDAPF
PDKTYQAGARAFPQLVPTSPDDPAVPANRAAWKVLGQWEKPFLAIFGARD
PILGQADRPLIKHVPGAAGQPHARIHASHFIQEDAGPELAERILSWQQAL
RS
>9myco-i2acb5 /F35/ Mycobacterium sp. Mycobacterium intracellulare; Mycobacterium avium; Mycobacterium yongonense; Mycobacterium indicus pranii, Haloalkane dehalogenase
MHVLRTPDSRFENLEGYPFVAHYLDVTASDTRPLRMHYLDEGPIEGPPIV
LLHGEPTWSYLYRSMITPLTDAGNRVLAPDLIGFGRSDKPSRIEDYTYQR
HVEWVVSWFEHLNLTDVTLLVQDWGSLIGLRIAAEQPDRVGRLVVANGFL
PTAQRRTPPAFHAWRAFARYSPVLPAGRIVGAGTVRRVSSKVRAGYDAPF
PDKSYQAGARAFPRLVPTSPSDPAIPANRRAWEALGRWEKPFLAIFGARD
PILGQADTPLIKHIPGAAGQPHARINASHFIQEDRGPELAARVLSWQQAL
L
>9myco-j5ee32 /F35/ Mycobacterium colombiense; Mycobacterium tuberculosis; Haloalkane dehalogenase
MHVLRTPDSRFENLEDYPFVAHYLDVTASDSRPLRMHYLDEGTIEGPPIV
LLHGEPTWSYLYRTMIPPLTDAGNRVLAPDLIGFGRSDKPSRVEDYTYQR
HVEWVISWFEHLNLRDVTLFVQDWGSLIGLRIAAEQPDRIGRLVVGNGFL
PTAQRRTPPAFYAWRAFARYSPVLPAGRIVSAGTVRRVPSKVRAGYDAPF
PDKTYQAGARAFPQLVPTSPADPAIPANRKAWDALGRWEKPFLAIFGARD
PILGRADSALIKHIPGAAGQPHARINASHFIQEDRGPELAERIQSWQQAW
L
>9myco-w9blw9 /F35/ Mycobacterium cosmeticum. Hydrolase or acyltransferase of alpha/beta superfamily protein
MEILRTPDDRFTDLPGYDFEPHYVEVTGADDTPVRMHYVDEGSPDGPVVL
LLHGEPSWCYLYRHMVPVLVDAGLRAVAIDLVGFGRSDKPSRRTDYTYQA
HVDWVRAAIDGIGLADITLVCQDWGGLIGLRLVGEEPDRFSRVVAANTFL
PTGDRPPGKAFLAWQQFSQQTPVFDAGAIVNGGCTSALSEDVIAAYNAPF
PDESFKEGARQFPTLVPTSPDDPATPANRAAWESLGRFEKPFLCAFSDSD
PITRGGDRVLAAHVPGARDHEPVTINDAGHFLQEDKGAELAAVVVGFIER
TT
>9noca-w8a428 /F35/ Nocardia seriolae N-2927. Haloalkane dehalogenase
MHALRTPDERFADLPDFPFGPHYLEVAAGDGSDTRLRTHYLDEGPRDGEV
VLLLHGEPSWSFLYRRIIPVLVVGGLRCVAPDLIGFGRSDKPAERADYSY
ARHVEWLREALFDHLDLSGITLVCQDWGGLLGLRLVAEHPDRFARVVVAN
TGLPTGDAKLTESFAAWQRFSQQTPSFPVGGIVAGGCRTELTPDVVAAYD
APFPDESYKAGARAFPLLVPTRPDDPAAPANRAAWERLAHFAKPVLTAFS
DGDPITAGGHRVFQEKVPGAAGQPHTTVLGGGHFLQEDRGPQLAALVREF
IAANPASDVTGGSTK
>9prot-a0a0f2rdt1 /F35/ Hyphomonas sp. BRH_c22 Haloalkane dehalogenase HLD1 DhxA
MPIDAKRTPDARFDNLPGFDYAPHYVDDLRGYEGLRIHYVDEGPQDAVRT
YLCLHGQPTWSYLYRKMIPVFLDSGARVVAPDWLGFGRSDKPVDDKVYSF
SFHRNMMVELIKRLDLKTVTLVCQDWGGLIGLTIPMDMPDTFERLIVMNT
TLATGTSPGAGFDQWKAYNRTQPDMDIAALMKRGTPILTDAEAAAYAAPF
PDATYKAGVRMFPELVMVSPGMEGVDISRRAAAWWANDWKGDSFMAVGAQ
DPVLGPAQMEKLRKTIRGCPEPMVLADAGHFVQEWGEPVALSALKSFGEL
>9psed-a0a0a1yq19 /F35/ Pseudomonas taeanensis MS-3. Haloalkane dehalogenase
MEFLRTPDACFANLPDYDFAPHYLMVDDTEGGQLRVHYLDEGPAEAAPVL
LMHGEPSWSYLYRKMVPTLVAAGHRVIAPDLVGFGRSDKPSRRDDYTYQR
HVDWMQSLLEQLKLDDITLVCQDWGGLIGLRLVAENPSRFARVVAANTML
PTGDHDPGTAFKSWQKFSQEVPEFPAGGIIKGATTTQLSQAVIDAYNAPF
PEEKYKEGARQFPLLVPITPDDPAAEKNRAAWSVLGQWQKPFLTAFSDSD
PITAGGDKLMQKLIPGTRGQAHTTIVNGGHFLQEDQGEKLAEVVVQFISD
TL
>9rhiz-a9dhk5 /F35/ Hoeflea phototrophica DFL-43 Haloalkane dehalogenase
MSNLLKIAAVTTLIALSSTLVVAEDAAPKLPAVAVSEELVIDRREIAVLG
STMSYLEEGEGDVVVFLHGNPSSAYLWRNVIPYVSSTHRVIAPDLIGMGE
SGKPDIAYTFADHARYLEAFVDELNLPAITLVSHDWGSALAWDFARRNPD
KVVRLAFMEGVLPPAFPQDSYQAMGEEMGGMFRALRDPEKGREMVMEGNM
FVESILPMMANRPLGEAAMETYRAPYSTVDSRLPTWMWPREVPINGMPAS
NVQLMQDIQTFMGKTDMPVLLAYAEPGVLVPPQAVPFYTDLIDNLETAFV
GQGLHFIQEDQPDAIGRAIADWLRRN
>9rhob-a0a2t6cbq8 /F35/ Sulfitobacter mediterraneus Haloalkane dehalogenase HLD1 DsmA
MQFLRTDDAHFDGLSDYAFSPNYLEVDDTEGGVLRVHFIDEGPRDAAPVL
LMHGEPTWSYLYRHMIPPLVAAGHRVIAPDLVGFGRSDKPTALEDYTYQR
HVDWMVSAVQQLDLQGITLFAQDWGGLIGLRLVAAMPDRFARLVVGNTAL
PTGDQPMNKAFESWREYALTVPDFNVGRIVYGGTTTKLTEAEVAAYNAPF
PEGRYQAGARKFPALVPCTPDDPAAPANRAAWQVLSGLSLPVLTTFGADD
KIMAGVEKVFQSQMPGAAGQDHVILPEAGHFLQEDVGPELARRIAEFIEK
TC
>9rhob-a3x6y8 /F35/ Roseobacter sp. MED193 Haloalkane dehalogenase
MVQNFRDKKKFATVLGKQMAYIEEGEGDPIVFLHGNPTSSYLWRNILPHL
AGRGRLIAPDLIGMGDSEKLEESGPDRYTFVEHRKYLFALLEQLGVTGNV
TLVIHDWGSGLGFHWAHMHPKALKGIAFMEGIVAPVPGWDSFPEAPRAMF
QSLRSEAGEEMVLEKNLFVEAILPGSILRDLNEEEMAEYRRPFANAGEDR
RPTLTWPRQIPIGGDPADVAEIVEAYSAWLRETSVPKLFVNAEPGALIAG
PVRDFVRSFPNLKEVTVAGSHFIQEDSPDEIGQAIKDWHSQL
>9rhob-b9nvf3 /F35/ Rhodobacteraceae bacterium KLH11 Haloalkane dehalogenase
MSSDKGISPDFPFDSKYVEVNGQRIHYVEEGESAPVLFLHGNPTSSYLWR
NIIPYAARHGRAIAVNLIGAGKSGKPDIPYRFVDHVPFVEGFIKALGLIN
VTLVIHDWGSALGFHYAHRHPENIRGIVFMEGIVRPMTWAGFPPDFRAGF
RMMRTPGLGWAMISGLNMFIEKILPSAIVRDLTPQEMEHYRVPFPTGRSR
KPVRMWPREIPIDGTPADVPDIVSGYSRWLGDTQTPMLMFHATPGGTIGP
KEVEWCREAISNLEVVDFGKGIHFLQEDVPHLIGQKLEE
>9sphn-a0a2d6h3s9 /F35/ Blastomonas sp. Haloalkane dehalogenase HLD1 DprxA
MTIEALRTPDEAFADVPDFDYPVHYADDLPGYEGLRAAWIDAGPADAGRT
FLCLHGEPSWSFLYRRMIPVFLESGARVVAPDLFGFGRSDKPVRQEDYSF
DFHRNYLLRLVERLDLRDITLVVQDWGGLLGLTLPVDDGFATRLSRLIVM
NTGIGQGTSPGPGFDAWKNYALSTPDLPVGRIIARGTPHLTEQEIAAYDA
PYPGPEYKAGAQIFPALVPISPDMPGVEHGQAAAHFWSERWSGESFMAVG
AADPVLGTEPMARLRSIIRGCPEPMIIPDGGHFVQEWGEQIARAALAAFG
DLPPA
>9sphn-a3wc35 /F35/ Erythrobacter sp. NAP1 Haloalkane dehalogenase HLD1 DexA
MKILTSDPARFANLPDYDFQEHWITIDLGEGYSGRMHYIDEGPKDAPPVL
LFHGEPSWSFLYRKMIPVLLDAGFRCLAPDLIGFGKSDKPDDIAFYTYDR
HISWLRQWRDAVVPAPAALFCQDWGGLLGLRLVGEEPDRFACVVASNTFL
PTGGTPSPAFLAWRQFAKSSPEFEIGELLQRATATERTPEEVAAYDAPFP
DEASKAGARAFPQLVPVEDGMDGIEQNTKAWEGLAAFDKPFLTLFGADDP
VTGGLGKTLSERIKGAEGMPHEILSTCGHFCQEDRPKELADGVVFAAKKA
GML
>9sphn-q2nc04 /F35/ Erythrobacter litoralis HTCC2594 haloalkane dehalogenase, putative
MTEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEA
GKTFLCLHGQPSWSFLYRKMIPVFTAAGGRAVAPDLLGFGKSDKPVDDET
YTYNFHRGMLIAFIEKLDLTSITLVCQDWGGILGLGIVPDMADRFERLIV
MNTAIPIGESPGPGFEAWKAFNRSQPNMDVAGLFKRGTPDLTDAEAAAYG
APFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWANEWSGKSFMAI
GMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESF
AA
>9spio-a0a0a0e285 /F35/ Spirochaeta sp. JC202. Haloalkane dehalogenase
MKILRTPDECFSNLTDYPFDPNYEEVSDADRGSLRMHYVDEGSRDADPVL
LMHGEPSWSYLYRKMIPTINRAGYRAVAPDLVGFGRSDKPSQRSDYTYQR
HVDWAQAWLDALDLQHITLVCQDWGGLIGLRLVADNPNRFIRVVAANTGL
PTGDTPISEAFLKWRKFSIEVPDFDVGAIIAMGCQKPLTDSVSAAYNAPF
PDDSYKAGARIFPSLVPIAPDDPASPANRKAWEVLSKFEKPFLTAFSDGD
PITRGGERIFQKRIPGAKVQPHTTIEGGGHFLQEDCGEELARVVVDFIRE
RV
>artat-a1r682 /F35/ Arthrobacter aurescens (strain TC1) putative hydrolase/amp-binding domain protein
MHGRGLRPERWNGGNRLVAANWPGVDPEWSRTLRVRSTSEVDAPGVLRRW
HVLDNGAQLSRRGLTPIGTLLCVHGNPTWSYLWRTLVRAGSDPAHPWRVV
AVDQLDMGYSERTGTFRRLADRINDLGDLTDALGLEGPVVTVGHDWGGVI
SSGWALEHPQQVTAVVLTNTAVHHPSDSPLPAALRLALHPAVHRWGTTTS
DAFLRVTHSLANPPLPADVGKAFMAPYRGAARRTGVGNFVADIPADPSHP
SFPALTRVAEGLRGLKVPALMLWGPTDPIFSDRYLKDLIARLPHADVHRF
EGAGHLVGEDRDIATPVFDWL
>aspcl-a1c8q9 /F35/ Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCT 3887 / NRRL 1) Haloalkane dehalogenase family protein
KHRFARDEVLRTERNGKGWMANMPWQDHTGEFTVCGATVRYVHLKPSYRS
VAQDVKTTHRPIVFLHGNPSWSFMWRDVFPALLERGHEVYAVDWLGHGRS
DKILRPEAITIELHTRTLMQFFEHTGVEDATLVAHDWGGCVAACTMPLLP
KSRCTSLLLLDSFLPPRPSETSLHNSLPYAIWAMTTEILGGCTPESAVMR
FLSPNISQKDLEGYTAPYQQLPGSAKSSIYRFSHMAPVVPRIILNCMRQT
WLWKLAEGLAGPSHFDNLNAQARLAVRDGEIRSFWKSSAKAQQLDLAVVF
GDMDPFLKDSKDVLVRSVNPRLMANWAPYGVWLDGAGHYPTEEKPAVVGD
LVARLARQRHTPAGG
>aspfc-b0yaj6 /F35/ Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) Haloalkane dehalogenase family protein
MEGQCGGVQRVRRDGPICPSNRVIAASQRIIRPPTDRSSFCMGIPAGAIC
GEMYAHGRFPLPWCLLTDGQVFPALVERGHEVYALDWLGHGRSDKITRPE
AITFELHMRTLQQFFESTGLDNTTIVAHDWGGCVALSTLSRLPTSACTSL
FLLNSLFPLRISEISMHYALLHAIWFMTTGILGGCTPESAVMRFMSPSIS
QNDVTGYAAPYRNLPSNAKSSIYRFSHMAPATPRIVLRSLRYTWLWKLVE
GLAGPSNFDNLTAQARLSLRNEGVRSFWKSSDRAHQLEVAVVFGDKDPLL
KDYKDILTVLAIIQPKRSRKPLGT
>aspfu-q4wbb4 /F35/ Aspergillus fumigatus Af293 haloalkane dehalogenase family protein
TYRFKDDEILRTDRKGKGWMADMPWRDNVEEFSVCGATARYVHLKPSYRS
IATDNKASHRPIVFLHGNPSWSYMWRNVFPALVERGHEVYALDWLGHGRS
DKITRPEAITFELHMRTLQQFFESTGLDNTTIVAHDWGGCVALSTLSRLP
TSACTSLFLLNSFFPLRISEISMHYALLHAIWFMTTGILGGRTPESAVMR
FMSPSISQNDVTGYAAPYRNIPSNAKSSIYRFSHMAPATPRIVLRSLRYT
WLWELVEGLAGPSNFDNLTAQARLSLRNEGVRSFWKSSDRAHQLEVAVVF
GDKDPLLKDYKDILVRGVDSRVMVDWAPYGIWLDGAGHYPAEEKPKAVGD
LIARLARYREPTVMQR
>aspnc-a2r4c0 /F35/ Aspergillus nige Catalytic Epoxide hydrolase
MPDIPWADCTEEMAICGATVRFVHQKPTLDGPAGRRRPIIFLHGNPSWSY
ICRNILPHLVDQGHEVYALDWLGHGRSDKATHPESVTFELHIHTLMQLFK
VHNLRHATIVAHDWGGCVALCAIPQLPQMACTRLLLLNSFLPPRPDEWNL
HYGLLYAIWFLSTGLLGGYVPESGVMRFMSPHLPQPEVDGYSAPYQSLPV
ATKASVFRFGHIVPVTPRFALHGLRQTRLWKLLEGLCGPRHFDNLSQQAR
LAKRGEEVRQSWRAGLEKGNPEVAVVFGEQDPLLKLYKDILVDCIHPAHM
VEWAPQGMWLSGGGHYPMEEKAADISLLAERLAS
>blasd-h6rk89 /F35/ Blastococcus saxobsidens (strain DD2). Haloalkane dehalogenase
MDIPRTPDDRFADLPGFPYQPRYVEIDDAEVGRLRVAYLDEGPADGETVL
LLHGEPSWSFLYRTMVPVLVEAGLRVVVPDLVGFGRSDKPADRSAYTYAR
HVAWMRRVLLDELDLRDLTFVGQDWGGLIGLRLVAENPDRFARVVVANTG
LPTGDQPMSEAFLAWQRFSQESPEFPIGRIVGNGTVGGLSPEAVAAYDAP
FPDDSYKAGARVFPALVPTSPDDPAAAANRAAWEVLRSWEKPFLTAFSDG
DPITGGGERVFQKLVPGAQGMAHTTLPGGGHFLQEDVGPELARVVVDLVA
ATPCPAQA
>burch-a0azu1 /F35/ Burkholderia cenocepacia (strains AU 1054; HI2424; MC0-3) Burkholderia sp. (strain 383) Haloalkane_dehalogenase HLDIII
MIRSDATFDGTFPFAPHFDDASGFRMHYVDEGPRDGEIVLCLHGEPTWGY
LFRHLVTALSPTYRVVVPDHMGFGKSATPQDRSYWLQDHIDNLERFVLAH
DLDRITLVMHDFGGPVGMGLAARHPDRIRRIVSANGPTPFGQTDLAERLT
ANGREAPWFQWIMRAAADGTLETVLGQLGFNILSTLKLNGFENHAIIADT
WIAAYGAPFAQPADCLGAIGWARGFAAGAHRFEEPDAAALRAIRGKPALA
IWGDADRTLGTEHFLPLFTALFPSAPIERLAGVGHYCFEDAPDAIAARIA
DFIRTTG
>catad-c7pwp0 /F35/ Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBR 102108 / JCM 14897) Alpha/beta hydrolase fold protein
MPLLPVLDSAIHYRESGDPNGLPFVFLHGNPTSSHLWRDVLPRVAAPGRR
LLAPDLIGMGASGKPDLAYSFDDHARYLDAWFDALGVDEAVLVGHDWGGA
LAFDRAARLPERVRGLAFAETIVKPLVGDEFPVAGRELFEQLRMPGVGEE
MVLEKSLFIEGVQGTLATPLDPADLDVYRRPFPTPESRRPILAWTRMMPL
DGEPADVVARVERYDRWLATSPEVPKLLVAFEPGPGAMTDAGAVAWCEAN
IAGLEVSRHGVAGHHCPEDRPEEMAAAINAWARRNSL
>cauce-r0el45 /F35/ Caulobacter crescentus OR37. Haloalkane dehalogenase
MDVLRTPDERFENLAGWPYAPRYTQVRDADGTELRIHHVDEGPRDQRPIL
LMHGEPSWAYLYRQVIADLTARGRRAVAPDLVGFGRSDKPAARADYTFER
HVAWMSAWLVQNDLKDIVLFCQDWGGLIGLRLVAAFPERFAAVVASNTGL
PIGVGKSEGFEAWLNFSQNTPELPIGFILNGGTARELSDAERAAYEAPFP
DETYKEGARIFPALVPITPEHPSVEENKAAWAVLERFEKPFVTAFSDADP
ITRGGEMVFQSRVPGARNAAHVTLKGGHFIQEDSPSEIAALLDGLVASLP
SQEPVA
>caucr-CC1175 /F35/ Caulobacter crescentus (and strain NA1000/CB15N)haloalkane dehalogenase, putative
MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPIL
LMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYER
HVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGL
PIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFP
DESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADP
ITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLP
QA
>causk-dhma /F35/ Caulobacter sp. (strain K31) Haloalkane dehalogenase
MQVLRTPESRFAGLADWPFAPHYAEITDAGGARLRLHYVDEGPRDGAPVL
LMHGEPSWAYLYRKIIPALAARGHRVIAPDLIGFGRSDKPAARGDYTYER
HVAWMSAWLEGLDLRGLTLFCQDWGGLIGLRLVAAFPERFAGLVIANTGL
PTGAGMTDGFKAWLDFSQNVPEMPIGLIVNMGTGRDLTPAEIAAYDAPFP
DETYKEGARQFPMLVPVTPEHASVAENLAAWKVLEHFPGPVVTAFSDGDP
VTRGGEAIFQSRMPGALGQPHRTLRGGHFLQEDCPDDIVDIVDAVARPES
QS
>caust-d5vky2 /F35/ Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059) (Mycoplana segnis). Haloalkane dehalogenase
MDVLRTPDERFEGLTDWPFAPRYTQITDPDGTRLRLHHVDEGPGDQRPIL
LMHGEPSWAYLYRKIIADLVARGRRAVAPDLVGFGRSDKPASRGDYTYER
HVAWMSDWLVRNDLKDIVLFCQDWGGLIGLRLVAAFPERFAAVVVSNTGM
PVGQGKTEGFEAWLNFSQNVPELPIGFILNGGTSRDLSDAERAAYDAPFP
DESYKEGARQFPALVPITPEHASIAENEAAWKVLERFDKPFLTAFSDADP
ITRGGEAIFQARVPATQKSKHVTLKGGHFIQEDAPAEIAALLDELVASLP
QPEAVA
>chlaa-a9wa35 /F35/ Chloroflexus aurantiacus (strains TCC 29366/DSM635/J-10-fl; ATCC29364/DSM637/Y-400-fl) Haloalkane_dehalogenase HLDIII
MVIHTEVPAPIRALFPFHVHEYALPAGVMRYVDEGSGTPVVLLHGNPTWS
FFYRRLIPLLRTQRRVIAPDHLGCGLSDKPQHYRYSLVNHIANLESLLTW
LDVGPVDLVVHDWGGAIGMGWAVRHPDLVRRIVVLNTAAFLSPHVPLRIA
AGKLPRLGEWAIRQLNAFAIAATTMAVTRPLPAAVREGYLWPYRTFADRI
AIARFVQDIPLHPGHPTWPVVDAIDRELVHLRDKPVRIFWGGRDWCFDDR
FLAGWLHRFPSAHVTRLDDAGHYVLEDASAEMIALLAHWLLSE
>chlad-b8g485 /F35/ Chloroflexus aggregans (strain MD-66 / DSM 9485) Haloalkane dehalogenase HLDIII DcagA
MPMTASFVHSPIRTLFPFQISAYTTPSGVIRYVDEGVGPPVVMLHGNPTW
SFFYRRLITALHNRRRVIAPDHLGCGLSDKPQNYHYCLANHIANLEQLLV
HLATGPVDLVVHDWGGAIGMGWAVRHPELVRRIVVLNTAAFLSPHIPLRI
AAAKMPRFGEWTVRRFNAFALAATVWAVERPLPPEVRAGYLWPYDTPAHR
IAIARFVQDIPLHPAHPTWPLIDAIDRELVCLRDKPMRIVWGGRDWCFDD
RFLAGWLKRFPDAEVTRLDDAGHYVLEDASDDVIARIARWLLVE
>colp3-q482y8 /F35/ Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) Haloalkane_dehalogenase HLDIII
MSDTMSKSMLENKLTKLFPFTRNFINRNGHQYHYVNEGQGSPVVMVHGNP
SWSFYYRNLVSQLSKSHQCIVPDHIGCGLSDKPDDDGYDYTLANRIDDLE
ALLEHLDVKENITLVVHDWGGMIGMGYAARHPERIKRLVILNTGAFHLPK
AKKLPPALWLGRNTFVGAALVRGFNAFSSVASYIGVKRKPMSKEVREAYV
APFNSWTNRISTLRFIQDIPLKIGDRNYQLVSDISDNLAQFKKIPMLICW
GLKDFVFDRHFLDEWQHRFPDAQVHAFDDCGHYILEDASDEVVPLIENFL
KTSETKLA
>conwi-d3f899 /F35/ Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) Alpha/beta hydrolase fold protein
MTPATWKDRKRKVRVDGLNMALVEAGAGEVTFVLLHGNPTSSFLWREVIP
RLEPLGRVVAPDLVGMGDSDKLPDSGPGSYTLVEHRRYLDGLLDAVVPDG
DVVLVIHDWGSALGFDWARRHPDRVAGIAYMEAIVRPLAWDEWPRGVETF
RRMRGEEGERWMLDDNMFVEQRLPAAVLRDLTDDELREYRRPFAEPGEGR
RPTLTWGREIPLGGEPADVAEIAQRYADWLSAAPLPKLFVNAEPGGILIG
TQREFCRTWPNQSEVTVPGIHYIQEDSGAEIGAAIADWWERVRAQRSA
>coxbu-CBU1225 /F35/ Coxiella burnetii 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase hydrolase, alpha/beta hydrolase fold family
MADYASRFVTVKGAKMHYIETGQGEPVLFIHGMPTSSYLWRNIIPKLADK
AHCVALDLIGMGESDKPDIDYTVNDHISYVECFIEALGLRNITLVMHGWG
SVIGFDYARRHPKNIKALAFFESHIRPTTDWDMLSLPVQQLATLLHRPGA
SYRAIVEQNYLINKLLPASMMRKLSDEEMANYRRPFLTKESRKPLWQYLQ
DLPLGDSKRPVVTLIKNYSQWLKQAPQPKLMMYAVPGFVTTMATVQWAKE
HLPNLTLVEFSDVLHFAQESIPDIFSEELRKWYLNEVRSVSFA
>desac-q1k1k2 /F35/ Desulfuromonas acetoxidans DSM 684 Haloalkane_dehalogenase HLDIII
MVKRLLPFQGNTLTLANNLRYHYLDKGQGDPVVMVHGNPSWCYYYRHLAV
ALSASHRVIVPDHIGCGLSDKPDDSRYRYTLEQRIADLETLLDHLQIKEN
ITLVVHDWGGMIGMAYATRYPERIKRCVVLNTGAFHLPPSKPLPKALKLC
RDSKLGAFLVRGFNAFSRGAAWVGCKINPMPPALRAAYMAPYNTWNNRIA
TLRFVQDIPLDPSDRAYAEVSRVADNLHLLVDKPMFIGWGEKDFVFDHHF
LAEWQKRFPNAQYHTWPRGGHYILEDVGDELIPLICRFIQETK
>emeni-q5b9i0 /F35/ Aspergillus nidulans FGSC A4 Haloalkane dehalogenase family protein (AFU_orthologue; AFUA_8G01700)
DGSYRFKPEEVFSIARNSRGWMETAPWANETEEFEVCGAKVRYIHLHASY
SSVLQDGKREHRPIVFLHGNPSWSYAWRNVFPSLLNRGHDVYTIDWLGHG
RSDKILQQEVITPELHIHTLVKFFEVTGLRNAIVAAHDWGGCIALCTIPR
LPAETVDKLFLLNTFFPPRLSDSSLHYRLLNRIWYCTTGLLGGYLPESMI
HRILEPSLSKADMHAFAAPYADVPRSAKSSITRFSHSVPSLPRFVLFQLR
QTRAWKLIEGLTGPANWDSLTTQARLSAQGDQVRRYWGAKDAVDKGCEIA
VVFGDKDPLIRDYKAVLTRAIHPDRMVAWAPRGMWIMNAGHLPMEGKAGE
VAGLIASYIVTLYGMRYALAAIRTCGLFI
>geoog-d2s432 /F35/ Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) Alpha/beta hydrolase fold protein
MAADVSPDDPFPRQRVRVDRRADGNLQMAYVEAGEGDPIVFLHGNPTSSY
LWRNVIPHVQHLGRCLAPDLIGMGESDKLPDPTRGSYSFSAHAGFLERFL
EAVGATERVTFVLHDWGSALGFDWAHRHPGAVRGIAFTEALVVPLTWADW
PAAARGIFRTMRGPDGEAAVLEKNVFVERILPASVARGLSAEAHARYREP
FADPAHRWPTLEWPRQLPIENVPPKVRDVVARYGQWLRTSDVPKLFVNAD
PGSILVGRPRAFVRKWEALTEVTVPGAHFVPEDSPHEIGRALADWIPTLR
>geour-a5gfj4 /F35/ Geobacter uraniumreducens Rf4 hydrolase, Haloalkane_dehalogenase HLDIII
MSIDIKKYYPFTGHNLNLDGLRYHYLDEGSGEPVVMVHGNPSWSFYYRNL
VLALRDRYRCIVPDHIGCGFSDKPGDDRYDYTLSRRVDDLERLLDSLGIS
KNITLVLHDWGGMIGMAYAVRHPKRIKRLVILNTAAFHLPKEKPFPLALK
ICRDTRLGALLVRGFNAFSLAASFVGCKKNPMSAELRQAYRRPYDTWQNR
IATIRFVQDIPLSPGDRNYNLVSEVAAGIDRFRNLPMAVFWGEQDFVFDC
SFLAEWQRRFPEAEVHRYSDAGHYILEDMKEEVVPLIGEFLDRT
>hahch-q2sav4 /F35/ Hahella chejuensis (strain KCTC 2396) Haloalkane_dehalogenase HLDIII
MDDQWINREEYPFASHYIELGPGRMHYVDEGQGKPIVMLHGNPTWSFLYR
NMIKGLSGQFRCIAPDHLGFGLSDKPGDWSYLPQDHARNLEILIKKLNLQ
DITLVVQDWGGPIGLSYALNHPQNVRRLVIMNTWMWSAHGDVKYETFSTL
MGGLFGRFMIKRFNVFVSVLLKQAVQKKLSADIYRHYSEPLKNPAERKGC
WVFPKQIIKADEWLEELWEKRANIADIPTLLLWGMKDFAFQERELRTWMQ
LLNHHTAVTFDDAGHFLPEDKGVEVCPLIADFLQDAEPTFQREASAPAPV
V
>isopi-e8r367 /F35/ Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) Alpha/beta hydrolase fold protein
MSTTVPSSHRLDRVEEFLAAHPGRRFATPSGPALVYRESGDPSTPPAILV
HGNPTWSYLFRRLIDPLAERFRVITMDHVGCGESDRPSEQTYGYRLADRV
ADLEALMDHLDPNRPFTLIAHDWGALIGLAAAVRRPHRFGRLAVMNTAAF
PLPANRPFPRELVVARLPLLGQFLVCRLNLFCKTAARRCVVHPLSTEVRR
GFLHPYDSPERRRAVHRFVRDVPLRPGDPSWDLLVQTSEGLQLFQDRPFW
IGWGQRDFLFDAPFLEEWRRRVPFAEYALFPNAGHYLLEDDFEAVASALI
EFVNRTECIFPPHQRLNPIQA
>jansc-q28p20 /F35/ Jannaschia sp. (strain CCS1) Haloalkane_dehalogenase HLDIII
MTGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPV
LLLHGNPTWSYLYRKFIPALAQTHRVIAPDHIGFGLSDKPEAEGDYTLDA
HIQNLEALVQQLDLTNITLVMQDWGGPIGLGMAARHPARIKALVVMKTFG
FYPPIDGVDPDKLKLPPPLLMMRAKGIGDFLVRRLGFFERQVMTMATATK
RKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQILMQETGPYID
QFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPD
QLIPELVEFLNRDV
>jansc-q28p25 /F35/ Jannaschia sp. (strain CCS1) alpha/beta hydrolase precursor
MKRIRALATAATLAAGLAMPVAAQDTGGAQQPISAEFPFELQTVEVLGSN
MAYVDTGDGPVVLFIHGNPTSSYLWRNVIPHVAEDHRAIAIDLIGMGASD
KPDIDYTFQDHYAHLEGFIDALELTDITLVLHDWGGGLGTYYAANNSDNV
RAIAMMEAAAPPALPIPDWAMVADQQTRETFQAFRDPVMGPQIILEQNGF
VEGLLPATILRTLSDAEMDAYRAPFPTPESRQPVLMWPNEIPIEGTPARN
VTVMEEVAAWLTTSEQPKLILYASPGLIWSPEVADFAARTFNNTEARFVG
AGIHFIQEDQPEAIGRNLSDWLRDRVTRGN
>kinra-q40yv4 /F35/ Kineococcus radiotolerans SRS30216 alpha/beta hydrolase fold:amp-dependent synthetase and ligase
TWHVLDTAPDAGPDDVVGTLLCVHGNPTWSYLWRGLASAASAVQLGWRVV
AVDQLEMGYSERTGTTRRLADRVEDLAGLVQALELSGEVVAVGHDWGGIV
VSGWAAGELARGGGRRDAGRHASTGPASPLRVAGLVVANTAASWPADAAA
PGVLKLALLPGVLPGVTSRSEVFLRTTLALPKPPLPAAVKAAYRGPYRSR
GERAGIEAFVADVPVGAGHPSRPALDAVTEGVAALAAAGLPTFVAWGPRD
PVFTEWFLRDWRARVPHADVHRFATASHLTPEDPQFAAAVLRWLD
>krifd-d2pqu1 /F35/ Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) Alpha/beta hydrolase fold protein
MTAETPQLMPVLDLRLGCRTVGEGRPVVFVHGNPTSSYLWRNVMSSRLGR
CLAVDLPGMGASDPVSGTDPRRYRFTTHQRYFDAFLHSLRLDQPVVLVGH
DWGGVLATDWARRHPDEVAGVAYLETLVAPVAWDSPNAPSPDVFRPLRSE
AGERLVLVENIFIEQILQAGTLRPLDDEDLAAYRRPYLEAGESRRPMLTW
AREIPIDGEPADVHELVGANARWMATSAVPKLFVNGSPGALLTGPLRDLC
RGWPGQQEVTVAGSHFLPEDSPAEIQEALAEWIPTLN
>marhy-h8w685 /F35/ Marinobacter hydrocarbonoclasticus; Marinobacter aquaeolei VT8; Marinobacter sp. Haloalkane dehalogenase
MRILRTDEARFAGLPDYPFSAHYLDVEPGLRMHYVDEGPAHADPVVMLHG
EPSWSYLYRHMIPLVAEAGHRVLAPDLIGFGKSDKPADVSDYSYDSHMRW
LTHWLETLDLTNVTLVCQNWGSLLGLRLAAEHHRRFSRIIVGNGMLPTGD
TRVPAVFRLWKAFASHSPWFPIGRIVQLGTERSLSPAEIAAYEAPFPTPD
YKAGARAFPALVPTSPNDPASAANREAWRVLEKWRKPFITCFSSGDPITR
GGDRYMQRRIPGAFGQPHITLNGGHFLQEDSPRQFARVILDALKAEMAA
>miclc-OleB /F35/ Micrococcus luteus (Micrococcus lysodeikticus) beta-lactone decarboxylase, haloalkane dehalogenase HLD-III OleB from OleBC fusion Mlut_13240
MPQIPAAPAALPPADRLPGWDPAWSRLVEIRSAADPEGTVRTLHVADTGP
VLAAAGAEIVGTIVAVHGNPTWSWLWRSLLAETVRRARRGMAAWRVVAPD
QLDMGFSERLAHAGSPSAASMGRAGDTYRTLGGRIADLDALLTALGLRDL
AATGHPLITLGHDWGGVVSLGWAARHPELVAGVATLNTAVHQPEGAPIPA
PLQAALAGPVLPASTVTTDAFLSVTTSLATPALDRETRAAYHLPYDTAAR
RGGVGGFVADIPADPGHGSHPELQRVGEDLAALGRTDVPALILWGADDPV
FLDRYLDDLRDRLPHARVHRYERAGHLLVDDRDITAPLLQW
>mycav-DHMA /F35/ Mycobacterium avium Mycobacterium paratuberculosis; Mycobacterium sp.; Mycobacterium tuberculosis haloalkane dehalogenase
MHVLRTPDSRFENLEDYPFVAHYLDVTARDTRPLRMHYLDEGPIDGPPIV
LLHGEPTWSYLYRTMITPLTDAGNRVLAPDLIGFGRSDKPSRIEDYSYQR
HVDWVVSWFEHLNLSDVTLFVQDWGSLIGLRIAAEQPDRVGRLVVANGFL
PTAQRRTPPAFYAWRAFARYSPVLPAGRIVSVGTVRRVSSKVRAGYDAPF
PDKTYQAGARAFPQLVPTSPADPAIPANRKAWEALGRWEKPFLAIFGARD
PILGHADSPLIKHIPGAAGQPHARINASHFIQEDRGPELAERILSWQQAL
L
>mycav-t2gun3 /F35/ Mycobacterium avium ; Mycobacterium gordonae; Mycobacteroides franklinii. Haloalkane dehalogenase HLD1 dhmA DmgoA
MQILRTPDQCFADLPDYPFQPHYIDVASGDGNTILRVHYVDEGPADAPPV
LLLHGEPSWSFLYRKMIPVITSAGLRAVAIDLVGFGRSDKPASRDDYTYQ
AHVDWTRAAIEAIGLTDITLVCQDWGGLIGLRLVGEDPDRFARVVAANTF
LPTGDRRLGKAFLAWQKYSQETPNFDVGKIVSGGCSTALTHDEIAAYDAP
FPDDTYKAGARQFPMLVPTSPDDAAAAANRAAWDALGRYDKPFLCAFSDQ
DPITGGADGVLRSLIPGAHAYEPVTITGAGHFLQEDNGRELASAVATFIA
ATSR
>mycav-x7u1u9 /F35/ Mycobacterium avium MAV_120709_2344. Haloalkane dehalogenase
MHILRTPDDRFVGLPDYKLEPHYVDVPTGDGGSLRMHYFDEGSADGQVVL
LLHGEPSWSYLYRHMIPVLVDAGLRTVAIDLVGFGRSDKPASREDYSYAA
HVAWMWAALEALQFNAITLVCQDWGGLIGLRLVGEHSDRFARVVAANTFL
PTGDHAPGEAFLAWQHYSQTAPEFAVGNIVDGGCVSQLTPAVRAAYDAPF
PDDSFKAGARQFPLLVPTMPDDPAAQANRAAWEALRHYDRPFLCAFSDSD
PITRGAEQALREHIPGAASHPPVTITGAGHFLQEDKGSELARVVADFVAS
TTDDS
>mycav-x7ubn6 /F35/ Mycobacterium avium MAV_120709_2344. Haloalkane dehalogenase
MRVLRTPNSRFEGLPDYEFAPHYVAVDRGDGVALRMHYLDEGPRRAPAIL
LLHGEPSWSYLYRHMIPVLVDAGLRAVALDLVGFGRSDKPAMRSDYTYLA
HVNWVKEALDTIGLDEITLVGQDWGGLIGLRIVGEEPERFSRVVAANTFL
PTGEQRGKAFLAWQRYSQETPSFDAGRIVNGGCTTNLTPDVIAAYDAPFP
GDSFKAGARQFPMLVPTSPDDPAAPANLAAMAALGRFTRPFLCAFSDQDP
ITRGADAVLREHIPGAKNIAPVTISGAGHFLQEDRGPQLAQVIAEFVHD
>mycka-x7yty4 /F35/ Mycobacterium kansasii; Mycobacterium gastri Haloalkane dehalogenase
MDVLRTPDARFQNLVGYPFAPHYVDVVATDTQALRMHYLDEGPTDGPPIV
LLHGEPTWSYLYRTMIPPLTEAGNRVLAPDLIGFGRSDKPTRIEDYTYLR
HVEWVTSWFENLDLHDVTLFVQDWGSLIGLRIAAERDARIAALVVANGFL
PTAQRRTPPAFYIWRAFARYSPVLPAGRIVDTGTVHKVPAEVRAGYDAPF
PDKRYQAGARAFPQLVPTSAGDPAIAANRAAWDALGRWEKPFLAIFGKRD
PILGRADRPLINHIPGAAGQPHARINANHFIQEDSGPELAERIISWQQAT
R
>mycmm-dhma /F35/ Mycobacterium marinum; Mycobacterium sp. Haloalkane dehalogenase
MDVVRTPDARFQNLVGYPFAAHYVDVAATDTPHLRMHYIDEGPADGPPIV
LLHGEPTWSYLYRTMIPPLAAGGYRVLAPDLIGFGRSDKPTRIADYTYLR
HVEWVKSWFEELRLAEATLFVQDWGSLIGLRVAAEHGDAIARLVVANGFL
PTARGRTPTAFHIWRAFARYSPVLPAGRLVAAGTVRKVPPAVRAGYDAPF
PDKSYQAGARAFPQLVPISPDDPAVAANRAAWDALGRWEKPFLAIFGERD
PLLGRADRPLIKHIPGAAGQPHARINANHFIQEDSGPELAERIISWQ
>mycpa-q744j6 /F35/ Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein
MHTLRTPDDRFHTVPDFPYPPRYCEVSDDDGGALRVAWVEDGPAGADPVL
MLHGEPSWSYLYRKMIPVLAGAGHRVVCPDLVGFGRSDKPTRREDHSYAR
HVEWMRALAFDVLDLHNVTLVGQDWGGLIGLRLAAEHPERFARLVVANTG
LPNGDQPMADVWWRFREAITSAPQLNIGAFVQGGCRRRLSDAERAGYDAP
FPSDEYCAGPRAMPTLVPTSPEDPAAAANKAAWAKLAVSPTPMLVAFSDS
DPITGPMAAIFQREMRGAQGIDHPLIRGAGHFLQEDAGAELAGHIVEFLR
R
>mycrh-g4i2j6 /F35/ Mycobacterium rhodesiae JS60. Haloalkane dehalogenase
MDVLRTPDERFTALPDFPFAPRYVEVDSGDGGTLRMHYLDEGRSDGEVVL
LLHGEPSWSYLYRWMIPVLVEAGLRAVAIDLVGFGRSDKPTSRDDYTYQA
HVDWMWAAIEEIGLADVTLVCQDWGGLIGLRLVGEHPDRFARVVAANTML
PTGDHHPGEAFLAWQKFSQEVPLFPAGQIVNGGSLSTLSAETIAAYDAPF
PDASYQAGARQFPMLVPISPDDPATPANRKAWAALGRFEKPFLSAFSDSD
PITGAAEPVLRGHVPGARGQSHVTIAGAGHFLQEDKGRELAEAVVTFVRA
NPRAELNSSSVDKLAAALEH
>mycs2-a0r5u5 /F35/ Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Haloalkane dehalogenase 1
MQTLRTPDERFAQLPEFPYAPMYCDIDDGEGGRLRVAWVEDGPAHAEPVL
LLHGEPSWSFLYRKMIPILVAAGHRVICPDLVGFGRSDKPTRIEDHTYAR
HVEWMRSLVFDALDLRKVTLVGQDWGGLIGLRLAAEHPDRFANIVVANTG
LPTGDIPMPDIWWQFRNAIQKAPKVDVGRFVASGCRRPLSDGVIAAYDAP
FPDDSYCAGPRAMPGLVPTSPDDPAAEANRAAWKVLRASKTPMLVAFSDG
DPITGGMAPIFKKEMRGAHGIEHPVISGAGHFLQEDAGEDLASAVVEFLR
DR
>mycsk-a1un18 /F35/ Mycobacterium sp. Alpha/beta hydrolase fold protein
MQTLRTPDERFLALPDFPYPPGYSDIDDGDGGRLRVAWVQDGPADGEPVL
MLHGEPSWSFLYRKMIPILAGAGFRVVCPDLVGFGRSDKPTRVEDHTYAR
HVEWMRTLAFDVLDLRGVTLVGQDWGGLIGLRLAAEHPDRFARIVVANTG
LPTGDFPMPDIWWQFRNAIQTVDDLDVGRWVQAGCAHPMSDEVRAAYDAP
FPDDSYCAGPRAMPLLVPTTPEDPASAANRAAWAALSASDTPMLVAFSDS
DPITGAMAPIFAREMRGAAGIDHPTIREAGHFLQEDAGEDLARAVVEFCR
RRSC
>mycsr-e6tfi3 /F35/ Mycobacterium sp. (strain Spyr1). Predicted hydrolase or acyltransferase of alpha/beta superfamily
MDVLRTPDERFTDLPGFPFDPHYVEVGGLRMHYLDEGPADGDVVLLLHGE
PSWSYLYRTMIPVLVDAGLRAVAIDLVGFGRSDKPADRADYTYQAHVDWT
WGAVAALGLADITLVCQDWGGLIGLRLVGEHPDRFARVVAANTTLPTGDQ
HPGDAFLAWQRFSQETPDFPVGHIVNGGCVSTLAPDVIAAYDAPFPDDSF
KAGARQFPTLVPTSPDDPAAPANRAAWEVLRRFDKPFLCAFSDSDPITRG
ADAALRTLIPGAHGQPEVTIAGGGHFLQEDRGPELAGVVVDFVRNTSV
>myctu-Rv1833c /F35/ Mycobacterium tuberculosis, Mycobacterium bovis, hypothetical protein Rv1833c Haloalkane_dehalogenase HLDIII, DmbC, dhmA2 Rv1833c
MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLY
RDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGL
DRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRV
MSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGV
AEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRL
SATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
>myctu-RV2296 /F35/ Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canettii DHA1 DHMA1 RV2296 gene
MDVLRTPDSRFEHLVGYPFAPHYVDVTAGDTQPLRMHYVDEGPGDGPPIV
LLHGEPTWSYLYRTMIPPLSAAGHRVLAPDLIGFGRSDKPTRIEDYTYLR
HVEWVTSWFENLDLHDVTLFVQDWGSLIGLRIAAEHGDRIARLVVANGFL
PAAQGRTPLPFYVWRAFARYSPVLPAGRLVNFGTVHRVPAGVRAGYDAPF
PDKTYQAGARAFPRLVPTSPDDPAVPANRAAWEALGRWDKPFLAIFGYRD
PILGQADGPLIKHIPGAAGQPHARIKASHFIQEDSGTELAERMLSWQQAT
>mycua-a0psi2 /F35/ Mycobacterium ulcerans (strain Agy99) Mycobacterium marinum (strain ATCC BAA-535 / M) Haloalkane dehalogenase
MGRQFTPDFTPDPKLYPFASRWFDSSRGRLHYIDESDGPPILLCHGNPTW
SFLYRHIIVALRDHFRCIAPDYLGFGLSEHPGTFGYKVDEHAQVVGEFVD
HLGLDNYLTMGQDWGGPISMAVAVERAERVRGIVLGNTWFWPADTLTMKA
FSTVMSSLPMQYAILHHNFFVERLIPAGTTHRPSSAVMEHYRGVQPTASA
RVGVAEMPKQILAARPLLARLASEVPAQLGTKPALLVWGMKDFAFRPEPM
LARMRAVFADHILVELPEAKHLIQEDAPDEIAAAIIARFG
>mycvp-a1t7p8 /F35/ Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1). Alpha/beta hydrolase fold protein
MDILRTPDERFADLPDFPFAPHYVEVDGLRMHYLDEGPADGPVVLLLHGE
PSWSYLYRRMIPVLVDAGLRAVAIDLVGFGRSDKPTRREDYTYQAHVDWT
WAAIEAIGLTGITLVCQDWGGLIGLRLVGEHPDRFARVVAANTTLPTGDQ
RPGEAFLAWQRFSQETPDFAVGHIVNGGCVSTLAPEVIAAYDAPFPDDSY
KAGARQFPTLVPTSPDDPAAPANRAAWEVLRTFDRPFLCAFSDSDPITRG
ADAPLRKFIPGAQGRPEVTIAGGGHFLQEDKGPELAAVVVDFIAANPV
>neofi-a1dal8 /F35/ Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRR 181) (Aspergillus fischerianus) Haloalkane dehalogenase family protein
KYKFKDDEIIRTDQKGKGWMANMPWRDNVEELNVCGATARYVHLKPSYRS
IATDNKASHRPIVFLHGNPSWSYMWRNVFPALVERGHEVYALDWLGHGRS
DKIIRPEAITFELHMRTLQQFFESTGLENATLVAHDWGGCVALSTLPRLP
TSACTSLFLLNSFLPPRISEISVHHALLYAIWSMTTEILGGCTPESAVMR
FMSPSISQKDVTGYAAPYRNLPSNAKSSIYRFSHMAPATPRVVLTSFRYT
WLWKLVEGLAGPSNFDNLTAQARLSLRNDEVRSFWKSSERARQLEVAVVF
GDKDPLLKDYKDVLVRAVDSRVMVDWAPYGVWLDGAGHYPAEEKPKAVGD
LIARLARYREPTVMGR
>nocfa-q5ywh1 /F35/ Nocardia farcinica Haloalkane_dehalogenase HLDIII
MQITFVPDATLYPFASRWFDSSVGRVHYIDEGAGPTILFCHGAPAWSFLY
RRIVRALRDRFRCVAVDHLGFGLSERPTGFGYTVAEHTAVLGELIDHLRL
EDFVVMGHDWGGPIGLGAAGARADRVRGVVLGNTALWPIDALANRVFSVV
MSSRPLQRRILEHNFLIDRVLLAELRGVLTKAEADHYRGVQPTPAARRGL
AVMPGQIRAARPLLEELARKVPERLGDKPTLAVWGMRDVVFRPSACLPRV
RAMFGDLEVVELSGARHFVQEHEPDAIAVAITERFS
>paesj-c6cxk3 /F35/ Paenibacillus sp. (strain JDR-2) Alpha/beta hydrolase fold protein
MTNMTIRADYPFESRYLNVNGHNLHYIEQGSGNPILLLHGNPTWSYMYRN
LIPYLDKLGRCIAVDLIGMGRSEKPDIGYTFLEQVDYVSKFIEQLGLKDI
IIVGHDWGMAIGLQYAGSHSENVTAVAMLEPQALYPCPDWEAFTPAESAE
LFQKLRDPEEGWPFMRDNNVFVEGMPHIIINRTFTVEEHEFYREPFRVPD
SRKPSWVFPNQIPIEGKPDEVAKAVELRNEWFTQTPIPKILFYADPGCTI
REPQMAWCREHLKNLTLFPIGKGFHHLLEENPHVIGQELQRWAGTLSR
>parl1-a7htj7 /F35/ Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) Alpha/beta hydrolase fold
MTTRTISAAEPPKKTVTIAGRSMAYSEMGEGDPIVFLHGNPTSSYLWRNV
MPHLADQGRCIAPDLIGMGDSDKLEPSGPERYTFREHRRFLESFLEALGI
HKNVTLVIHDWGSALGFDWANRNRGAAEGIAYMEGIVRPLEWDEWNEDAR
RIFEGFRSDAGEEMILKKNLFIEAVLPGSILRKLTDEEMAVYRRPFANEG
EDRRPTLSWPRQIPLGGEPENVVESVADYAHWMSENDLPKLFVNADPGAI
LTGAQREFCRSWKNQTEVTVKGSHFIQEDSPHEIGEAIAKWRRSWRAAPK
A
>pepld-a1atm7 /F35/ Pelobacter propionicus DSM 2379 Haloalkane_dehalogenase HLDIII
MVSDPLKRHYPFQSHHLDLDGLAYHYLDEGSGPAVVMLHGNPSWSFYYRN
LVRELSASYRCIVPDHIGCGLSDKPGDERYDYTLARRVQDLERLLDHLAI
RDNITLVVHDWGGMIGMAYAVAHPRAIRRLVVMNTAAFQLPPGKPFPLAL
RICRDTRLGSLLVRGFNAFSLAASFVGCKRNPLSRELRRLYRLPYGSWND
RIATLRFVQDIPLKPGDRGFDLVNSVDRGLDQFRDLPLLLVWGERDFVFD
RHFLAEWRRRFPQAEVHSYADAGHYILEDMKDEVVPIISAFLKRTE
>phezh-dhma /F35/ Phenylobacterium zucineum (strain HLK1) Haloalkane dehalogenase
MQVLRTPDERFEGLADWPFAPKYVQVKDADGTLLRIHHVDEGPRDGAPVL
LMHGEPSWAYLYRHIIPRLVAAGHRAIAPDLVGFGRSDKPADRGDYTYAR
HVAWMSAWLEAVDLRGAYLFCQDWGGLIGLRLVAAYPERFAGVVVSNTGL
PVGGGAMTDGFKAWLQFSQTVPELPIGFLLNGGSVRELSAAEMAAYDAPF
PDESYKEGARQFPALVPVTSEHAGVAENQAAWKVLEAWDKPLVTAFSDGD
PITKGGEVPFRERVPGARGQPHVTLHGGHFVQEDSPAEIAGLLDGLIRRS
R
>phopr-Q93CH1 /F35/ Photobacterium profundum (Photobacterium sp. (strain SS9))(and strain 3TCK) putative haloalkane dehalogenase HLDIII DpproA
MLDTLFPFKRNFLSRNGHKLHYVNEGQGEPVVMVHGNPSWSFYYRNLVTE
LSQNHQCIVPDHIGCGLSDKPDDAGYDYTLKNRIDDLEALLEHLEVRENI
TLVVHDWGGMIGMGYAARYPDRIKRLVILNTGAFHLPDTKPFPWALWICR
NTLLGTGLVRGFNAFSSIASYIGVKRKPMSPEVRKAYVSPFNSWANRIST
LRFVQDIPLRKGDRNYELVSEIAASLPKFSHVPTLICFGLKDFVFDKHFL
AVWREKMPHATVHEFEDCGHYILEDASDEVVPLISDFMKMPLATDNKPSE
ADL
>psea6-q15uk5 /F35/ Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087). Alpha/beta hydrolase fold familiy
MQYLRTSDDCFEGLSGYSFAPHYIEVDDFEGGNLRMHYLDEGSKEGEVVL
MLHGEPSWSYLYRDMIKPIADKGYRVIAPDLIGFGRSDKPTQRCDYTYQR
HLDWIRNILTQLNLKQVTLVCQDWGGLLGLRLVAEHPELFARVLAANTML
PTGDHPPGEAFMKWRAFSQEVPEFPVAGIIKGATVTALSTDVLNAYDAPF
PTEAHKAGVRQFPLLVPATTDDPQTQNNRKAWQVLQQFNKPFITAFSDSD
PVTAGGDKIMQKLIPGTQGQSHTTITQGGHFLQEDQPQQLAKVLLQFIND
NPISTD
>psyck-q1qbb9 /F35/ Psychrobacter cryohalolentis, Psychrobacter sp., alpha/beta hydrolase fold
MKILRTPDSRFANLPDYNFDPHYLMVDDSEDSELRVHYLDEGPRDADPVL
LLHGEPSWCYLYRKMIPILTAAGHRVIAPDLPGFGRSDKPASRTDYTYQR
HVNWMQSVLDQLDLNNITLFCQDWGGLIGLRLVAENPDRFARVAAGNTML
PTGDHDLGEGFRKWQQFSQEIPQFHVGGTIKSGTVTKLSQAVIDAYNAPF
PDESYKEGARQFPLLVPSTPDDPASENNRAAWIELSKWTKPFITLFSDSD
PVTAGGDRIMQKIIPGTKGQAHTTIANGGHFLQEDQGEKVAKLLVQFIHD
NPR
>psyin-a1sw98 /F35/ Psychromonas ingrahamii (strain 37) hydrolase, Haloalkane_dehalogenase
MNLDTLFPFKRNYLDRNGQQYHYLNEGSGEPVVMVHGNPSWSFYYRNLVK
SLSRNYQCVVPDHIGCGLSDKPADKDYQYTLKNRIDDLEALLDSLNINEN
ITLVVHDWGGMIGMGYAARHPERIKRLVILNTAAFHLPSTKSFPVPLLIG
RNTYIGTVLIRGLNAFSAIASYVGVKRKPMEKAVRQAYVAPFNSWKNRIS
TLRFVQDIPLLPHHKNYQLVSDISDSLIHFQKIPTIICWGMKDFVFDKHF
LNTWKEKMPHAVVHEFDDCGHYILEDASEQVIPLIETFMAENP
>rhil3-q1m5k0 /F35/ Rhizobium leguminosarum bv. viciae (strain 3841) bv. trifolii (strain WSM1325) putative haloalkane dehalogenase
MPTIDTLASFISYEELGEGDPIVFLHGNPTSSHLWRNIMPGIGPGRCLAP
DLIGMGRSGKPDIGYRYGDHIAYLDAWFDALDLDGVVLVGHDWGGALAFD
WASRQPGRVRGIVVMETILRPMSWEDLPGGGKARYELLRGAGTGEAKVLD
ENFFIEQALRATTLKGLSDFDWDVYRAPYPDRDSRRPLLEWPRAMPINGE
PADVVARIEAYDRWLSASPEVPKLLLTFEGPSETLLIGSEMISWCRDNIA
GLEIKGCGPARHIAPEDQPEAIAAEIKSWIDRRGLRATHRKVASQA
>rhoba-DHLA /F35/ Rhodopirellula baltica haloalkane dehalogenase (EC 3.8.1.5) HLDIII DHLA DrbA
MSCRLSSNRRGSSKLAAMTNLASDLFPHPSSELSIDGHTLRYIDTAASSD
IPSSAVGSSDGEPTFLCVHGNPTWSFYYRRIIERYGKQQRVIAVDHIGCG
RSDKPSEDEFPYTMAAHRDNLIRLVDELDLKNVILIAHDWGGAIGLSAMH
ARRDRLAGIGLLNTAAFPPPYMPQRIAACRMPVLGTPAVRGLNLFARAAV
TMAMSRTKMKPDVAAGLLAPYDNWKNRVAIDRFVRDIPLNDSHPTMKTLR
QLESDLPDLASLPISLIWGMKDWCFRPECLRRFQSVWPDAEVTELATTGH
YVIEDSPEETLAAIDSLLARVKERIGAA
>rhoer-c3jvx6 /F35/ Rhodococcus erythropolis (strains SK121; PR4 / NBRC 100887) Haloalkane dehalogenase
MPTIPVLDSTMAYRSRGEGPPFVLIHGNPTSSHLWRNILPQIGNLGRALA
PDLIGMGRSGKPPINYGFLDTARYLDAWFDQMELDDVVLVGHDWGGALAL
DWAARHPDRVRGVAFFETILRPMTWDEHFPGEARARVEALRDSDTGETKV
LDENFFLEIALHRTVLGEMTETDAEAYRSPYPSRESRRPLLEWPRSFPIE
GTPGDVNARVAAYSDWLAKSTDVPKLLLTFSGPAELLMIGPDEVTWSRSN
IANLEVEQCGPAGHLAPEDQPAAIAAAITEWTERQHCFNRE
>sacvd-DsvA /F35/ Saccharomonospora viridis Haloalkane dehalogenase with unusual catalytic residues
MRLLRTPEDRFSDLPDFDYPPLYADIEHPLAGIIRVGYVEAGPPDGPTVL
LLHGEPSWSFLYRKVLPVLAEAGIRAIAPDLVGFGRSDKPADMADHTYAR
HVEWMRAFAFDVLDLRDVVLVGQDWGGLIGLRLVAENLDRFVGVVAANTG
LPTGDQAMPEEWWAFRDATQKAPVFDTARFIQSGCRRTLTAAERAAYDAP
FPNEMYKAGPRALPTLVPTSPDDEASEANRAAWRTLTTSNVPFLCAFSDG
DPITGAMGPILQRAMPGAAGREHPTIANAGHFLQEDAGQELGRVVARFVR
GLD
>salrd-q2s473 /F35/ Salinibacter ruber (strain DSM 13855) haloalkane dehalogenase HLDIII
MPSAPTAPDATRTVQTPAGPLAYTDAGSGPPVVFLHGNPTSARLYRHLLR
DLARDHRCIAPDYLGFGRSAAPPGFSYRPPAHAVLVERLLCALDLSDLTL
VLHDWGGPIGMAYALRHPDTVRRLVLMNTWAWPLTHRPLLQGASRLLATP
AGRLAVEHGNAFARIVMPMTTGGGPQHDWITDYAAALDSRPRRHACWAFA
RALRTEADWLRALWTRRHRLRDCPALLCWGMADPAFGTEACLRRWQNVVS
GTAVRRYPSVGHYVPEELGPALVDPVRRFLAP
>serod-d4e081 /F35/ Serratia odorifera DSM 4582 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase
MTVYVYIGQATDYLAQEDIAMPAISVLDSIIHYEQNGVGTPLVFLHGNPT
SSYLWRNILPAIEGPFRCLAPDLIGMGQSGKPPLNYDFSDHARYLNAWFD
VMGLQDMILVGHDWGAALAFDWAAHHPERVRGIAFMEAVIRPMSWDSLPT
EVAARFKALKTPGLGEKIVLDGNEFIEKTLRATVLSPLSEQDIQCYTAAY
TTADSRRPLLEWSRSMPFDGEPADVVRRMAFYHRWLGNSKDTAKLLLSFD
GVAGGLAINQPMIAWCQANIANLDVIPCGAAKHNAPEDRPTEIASAINQW
LAKC
>sheam-a1s4t4 /F35/ Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) Haloalkane_dehalogenase HLDIII
MDNHKMLDSLLPFKRRFFNHGGHNIHFIDEGPEGDVAPKGTVVMVHGNPS
WTLYYRNLIRALKGEYRCIAMDNVGCGLSDKPDDSRYHYTLTSRIGDLEA
LLASLNVTEKVTLVVHDWGGMIGMGWATKYPDAIERLVILNTAAFHLPAT
KPLPLRLKICRDTWLGTLLVRGFNAFAGLASVIGCKRNPMNAEMRRAYVA
PFNSWANRISTLRFVQDIPLKPGDTAWDEVSRIEQSLAQFTRVPTLICWG
LKDFVFDRHFLTVWQEKLPQAEVHAFEDCGHYILEDASDEVIAHIERFVA
ASAPAEALAS
>shedo-q12ph0 /F35/ Shewanella denitrificans OS217 Haloalkane_dehalogenase HLDIII
MLDTLLPFKSHFLSRNGQQLHYLNEGEGEAVVMVHGNPSWSYYYRNLVAE
LKGEYQCIVPDHIGCGLSDKPDDPQYDYTLKSRIDDLEALLEHVEVRENI
TLVLHDWGGMIGMGFAARHPERIKRLVLLNTAAFHLPQSKPFPWALWICR
ETFLGTLLVRGFNAFSAAASYVGVKRKPMDNAVREAYVAPFNSWTNRIST
LRFVQDIPLKPSDRNYQLVSDIADSLSQFKQTPALICFGMQDFVFDKHFL
QEWRRRLPNAKVHEFADCGHYILEDAPDEVIGLVKDFLTGTESEKTH
>shefn-q082b3 /F35/ Shewanella frigidimarina (strain NCIMB 400). Alpha/beta hydrolase fold
MEFLRTDDSFFANLPDYQFTAHYLTVDDTEGGELRVHYLDEGPKDAAPIL
LLHGEPTWSFLYRKMIPILVKAGHRVIAPDLIGFGRSDKPTKRHDYTYQR
HVDWMKSFMLQLILTDITLVCQDWGGLIGLRLAAEESERFARIVCANTML
PTGDHPPGEAFTKWRQFSQDVAIFPTGNLINSACVSTLTVEIIAAYDAPF
PDERYKEGARQFPLLVPITPDDPAADKNRAAWKVLNQWKKPFLTVFSDSD
PITAGGDALMQKLIPGTKGQKHTTIVAAGHFLQEDKGEVLADVVVNFIAD
NR
>shefr-q3nsz6 /F35/ Shewanella frigidimarina NCIMB 400 haloalkane dehalogenase (EC 3.8.1.5)
MEFLRTDDSYFVNLPGYPFTPNYLLVDDTEGGQLRIHYLDEGDKDAEPIL
LLHGEPSWSFLYRKMIPILVEAGYRVIVPDIIGFGRSDKPSKRSDYTYQR
HVDWMKSFVLQLELTNITLVCQDWGGLIGLRMAAEDIPRYTGIVAANTML
PTGDEETNDAFMKWFNYSQESVDFPAGQMINGASVSDLSDDVIAAYDAPF
PDETYKTGAREFPLLVPITPDDPATLKNRAAWKVLSQWNKPFLTAFSDSD
PITAGGDKMMQEIIPGTKGQKHTTIVNAGHYLQEEQGEVLAKVIVNFIAD
NR
>shefr-q3nuz7 /F35/ Shewanella frigidimarina NCIMB 400 Haloalkane_dehalogenase HLDIII
MLDNLLPFKSHYLDRNGNKLHYINEGQGEPVVMVHGNPSWSYYYRNLVSA
LSDKHQCIVPDHIGCGLSDKPDDPQYDYTLKNRIDDLEALLDSLDVKQNI
TLVVHDWGGMIGMGFAARHPERIKRIVCLNTAAFHLPKTKPFPWALWICR
ETLLGTLLVRGLNAFSSAASYVGVKRKPMSKEVREAYVAPFDSWKNRIST
LRFVQDIPLKPGDRNYDLVTSIGDSLSEFAEVPTLICFGLQDFVFDKYFL
EEWRQRMPHATVHEFADCGHYILEDASDEVIGLIKDFIAKN
>shehh-b0tml1 /F35/ Shewanella halifaxensis (strain HAW-EB4) Haloalkane dehalogenase HLDIII DshA
MLDTLHPFKRNYLDRNGNKLQYVNEGQGEPVVMVHGNPSWSFYYRNLISA
LSDKHQCIVPDHIGCGLSDKPDDNGYDYTLKNRIDDLEALLEHLDVKQNI
TLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPASKPFPWALSICR
NTMLGTFLVRGFNAFSSAASYVGVKRKPMHKDIREAYVAPFNSWANRIST
LRFVQDIPLKPGDRNYELVSEIAASLSKFQDIPTVICWGLQDFVFDKHFL
TEWKQRMPHAKVHEFSDCGHYILEDASDEVIGHIKEFMAKTEQQTATESV
A
>shelp-a3qdn3 /F35/ Shewanella loihica (strain ATCCBAA-1088/PV-4) Haloalkane_dehalogenase HLDIII
MLDSLFPIKRNYLDRNGHKLQYVNEGQGEPVVMVHGNPSWSFYYRNLVTA
LSPNHQCIVPDHIGCGLSDKPDDAGYDYTLKNRIDDLEALLDHLEVKEKI
TLIVHDWGGMIGMGYAARHPERIKKIVVLNTGAFHLPEAKPFPWALWICR
NTLLGTVLVRGFNAFSSIASYVGVKRAPMPKAIREAYVAPFNSWANRIST
LRFVQDIPLKPGDRNYELVSEISEKLNQFNQLPMMICWGLKDFVFDKHFL
DEWKRRFPEAEVHEFADCGHYILEDASDEVVAQVQQFMAR
>sheon-SO1743 /F35/ Shewanella oneidensis (Shewanella sp. MR-4; MR-7; ANA-3; Shewanella baltica (strain OS155 / ATCC BAA-1091) hydrolase, Haloalkane_dehalogenase HLDIII
MLDTLLPFKRHFLSRNGNKLHYINEGQGEPVVMVHGNPSWSFYYRNLVSA
LKDTHQCIVPDHIGCGLSDKPDDSGYDYTLKNRIDDLEALLDSLNVKENI
TLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPDTKPLPLALWICR
NTLLGTVLVRGFNAFSSIASYVGVKRQPMSKYIREAYVAPFNSWANRIST
LRFVQDIPLKPGDRNYQLVSDIAASLPKFAKVPTLICWGLQDFVFDKHFL
VKWREHMPHAQVHEFADCGHYILEDASDEVITHIKHFMTETETLATQVNP
ADSITEFESASQAPQAER
>shesw-a1rld1 /F35/ Shewanella sp. W3-18-1 Shewanella baltica OS155 Shewanella putrefaciens (strains 200; CN-32/ATCC/BAA-453) Haloalkane_dehalogenase HLDIII
MLDTLLPFQRHFFNRNGNKLHYINEGHGEPVVMVHGNPSWSFYYRNLVSA
LKDSHQCIVPDHIGCGLSDKPDDSGYDYTLKRRIDDLEALLDSLNIKENI
TLVVHDWGGMIGMGYAARYPERIKRLVILNTGAFHLPESKPFPWPLWICR
NTLLGTVLVRGFNAFSSIASYVGVKRQPMAKYIREAYVAPFNSWSNRIST
LRFVQDIPLREGDRNYQLVSDIAASLPKFAKVPTLICWGLKDFVFDKHFL
AKWRQHMPHATVHEFADCGHYILEDASDEVIAHIKGFMADEQVASASAER
AAG
>sorc5-a9fvz2 /F35/ Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) Haloalkane dehalogenase
MGTSSKKRVCIEGHEMAYVDQGMGEPVVFLHGNPTSSYLWRNILGPTSAR
RRCLAPDLIGMGDSDKLPETGRQAYGYATHARFLDAWFDAVVPAEPVVLA
VHDWGSALGFDWARRHPDRVRGVAYMEAIVGSMPLGKWPAAAREFFEAIR
SDAGEELVLEQNVFLERTISEGSMLRPLSDEERAEYRRPFLVPGEGRRPT
LSWPRLLPFDGEPKAICALADAYVAWLTASSVPKLFVNAEPGRILTGELR
EICRRFPNQREVTVRGLHYPQEDSPMEIADALAGWLDTLAPPTRAQPVAS
>strav-SAV4779 /F35/ Streptomyces avermitilis putative haloalkane dehalogenase
MPVQHILDSTMYHRESGTGVPIVFLHGNPTSSYLWRDVMPAVGSGRLLAP
DLIGMGESGKPALDYTFADHARYLDAWFDALDLRDVILVGHDWGGALAFD
WAARHPHRVRGIAFTETIVKPMAWAEFPEGGRELFRAIKTRGVGESMILD
DNAFIEQGLPGSSATALTEGDLDVYRKPYPTRESRLPLLRWPRSMPLGGE
PADVVARIEAYDRWLKASVDVPKLLLTFAPGPGAMMHEGIVAWCAANIAG
LEIEHSEAVAGHHTPEDQPVLIARAISAWADRLGLRLS
>strrd-d2auf6 /F35/ Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) Haloalkane dehalogenase
MPVQPVLDSTISYREAGTGVPMVFLHGNPTSSHLWRHIMPAMGDSGRRLA
PDLIGMGESGKPDIAYTFDDHARYLDAWFDALGLDDVVLIGHDWGGALAF
DWAARHPGRVRGIAFTETIVKPMSWQEFPEGGRGLFEAIKTPGVGEAMIL
DENMFIEQALPGTVVTPLGEEDLDTYRRPYPTRDSRRPLLQWPRAMPLGG
EPADVVARIEFYDEWLAASVEVPKLLITFAPGPGAMMGPEIIDWCAANMA
GLEIDEHPMPAGHHTPEDQPEAIAASIVTWADKHDLRSDARS
>strrd-d2ba59 /F35/ Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) Haloalkane dehalogenase
MRTVAVIDSYLAYTETGEGESPLVFLHGSPTSSYIWRNVIPHVADHARIL
APDLIGMGASGKPDIGYRFADHARYLDAWFEAMGLEEAVLVGHDWGGALA
MDRAARHPGLVRGVALLETFLRPQLWAELPQDVIDHSQALRTPGLGERLL
LEENAAIEYALPHPFAIKTGLSPEDHDVYRAPYPDPASRRPLLQWPREVP
YDREPADVAERMDAYGTWLATSPEVPKLLLTVEDGVGIASPQIVDWARQN
IAALEIEGIGPAGHQAPEDRPHAIGQAIAGWLNRHRLLSPARASA
>strrd-d2be60 /F35/ Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) Alpha/beta hydrolase fold protein
MISTEERYRKRRIEIDELEMAYVDEGEGDPIVFLHGNPTSSYVWRNVIPH
LTGNGRCIAPDLIGMGDSAKLPDSGPGSYRFVEHRRYLDAFLRALGVRER
VVLVLQDWGSALGFDWACRHPAAVRGIAYMEAFVTPIPSWSDWPEAAVAF
FQAIRSDVGEEMVIDRNIFVDDVLPSEVLRGLSEEAMAVYRRPYTEPGES
RRPTLTWPREVPVAGEPRDVHDIITRYAEWLADSPVPKLFVEAVPGTMFE
THRAIARSWPNQAHVTMKGGHMVQEDAPDEIGNAIASWLRDLSS
>xanau-halo1 /F35/ Xanthobacter autotrophicus, Xanthobacter flavus, Ancylobacter aquaticus, haloalkane dehalogenase DhlA
MINAIRTPDQRFSNLDQYPFSPNYLDDLPGYPGLRAHYLDEGNSDAEDVF
LCLHGEPTWSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPVDEEDYTFE
FHRNFLLALIERLDLRNITLVVQDWGGFLGLTLPMADPSRFKRLIIMNAC
LMTDPVTQPAFSAFVTQPADGFTAWKYDLVTPSDLRLDQFMKRWAPTLTE
AEASAYAAPFPDTSYQAGVRKFPKMVAQRDQACIDISTEAISFWQNDWNG
QTFMAIGMKDKLLGPDVMYPMKALINGCPEPLEIADAGHFVQEFGEQVAR
EALKHFAETE
>xanax-DHAA /F35/ Xanthomonas axonopodis (pv. citri) Xanthomonas campestris (pv. campestris (strains 8004; B100; 85-10; vesicatoria ATCC 35937), pv. vesicatoria (strain 85-10)) haloalkane dehalogenase HLDIII
MNYPGYPFPPKRLEVRPGVAMSYLDEGPRDGEVVVMLHGNPSWSYLWRHL
VSGLSDRYRCIVPDHIGMGLSDKPDDAPDAQPRYDYTLQSRVDDLDTLLR
HLGITGPVTLAVHDWGGMIGFGWALSHHAQVKRLVITNTAAFPLPAEKPM
PWQIAMGRHWRPGEWFIRTFNAFSSGASWFGVSRRMPADVRRAYVAPYNN
WRNRISTIRFMQDIPLSPADQGWSLLERSAQALPAFADRPAFIAWGLRDI
CFDKHFLAGFRRALPQAEVTAFNDANHYVLEDKHEVLVPAIRAFLERNPL
>xancp-OleB /F35/ Xanthomonas campestris beta-lactone decarboxylase, haloalkane dehalogenase HLD-III OleB
MTYPGYSFTPKRLDVRPGIAMSYLDEGPRDGEVVVMLHGNPSWSYLWRHL
VSGLSDRYRCIVPDHIGMGLSDKPDDAPDAQPRYDYTLQSRVDDLDRLLQ
HLGITGPITLAVHDWGGMIGFGWALSHHEQVKRLVITNTAAFPLPPEKPM
PWQIAMGRHWRLGEWFIRTFNAFSSGASWLGVSRRMPAAVRRAYVAPYDS
WKNRISTIRFMQDIPLSPADQAWSLLERSAQALPSFAGRPAFIAWGLRDI
CFDKHFLAGFRRALPQAEVMAFDDANHYVLEDKHEVLVPAIRAFLERNPL
>xanor-q5gv06 /F35/ Xanthomonas oryzae pv. oryzae (and strain MAFF 311018) haloalkane dehalogenase HLDIII
MNYPGYPFTPKRFEVRPGVAMSYLDEGPRDGEVVVMLHGNPSWSYLWRHL
VRGLCDRYRCIVPDHIGMGLSDKPDDAPDAQPRYDYTLQSRVDDLDTLLR
HLGITGPVTLAVHDWGGMIGFGWALSHHAQVKRLVITNTAAFPLPAEKPM
PWQIAMGRHWRLGEWFIRTFNAFSSGASWFGVSRRMPAAVRRAYVAPYNT
WRNRISTIRFMQDIPLSPADKGWSLLERSAQALPTFAERPAFIAWGLRDI
CFDKHFLAGFRKALPHAEVTAFDDANHYVLEDKHEVLVPAIRAFLERHPL
>xylfa-XF1965 /F35/ Xylella fastidiosa(strains Ann-1; Dixon; Temecula-1; M-12) haloalkane dehalogenase HLDIII
MSYHDYPFLSQCFEVRPGIRMRYLDEGPRDAAVVVMLHGNPSWSYYWRHL
VAALRDGYRCIVPDHIGMGLSDKPGDAPGVVPRYDYTLQSRVDDLDALLR
HVGIDDVTPLTLAVHDWGGMIGFGWALAHAVQVRRLVMTNTAVFPMPTSK
KMPWQIALGRDWRFGEWMVRGLNAFALGAAWLGVETRLPRAVRRAYLAPY
NSWANRISIIRFMQDIPCGPGDRAWPLLEATGKALPDFADRPVFIGWGMQ
DIVFDHHCLDEFRAALPGAQVQVFADAGHYVLEDKSSVLVPAIRAFLDAH
P