>9alte-a3jf54 /F89/ Marinobacter sp. ELB17 Biotin biosynthesis protein
MARTSSLVVIGGWGVSAAMLEPVYRYWQGVVQVVSLTDDGLSSCNSPAHA
AAILLQRYPQPAVWLGWSLGAQVAMAAAQANPHSVNKVVTLGGFPQFVAS
QNWPWGVSPAIFRRFERYFEREPQACRASFFAQMIDGSEHQAEQVRAIKA
WLKQGLPEPIEPLAKGVRWLRHCCQLHTWQQCPVPTLHLRGSCDAVVPPW
AQHLAMPVHSRALTIDGMGHWPGEFYGPECWQAIHDFLTSSHDVCH
>9alte-a6f3i0 /F89/ Marinobacter algicola DG893 Biotin biosynthesis protein BioH
MNAVESRIPLVVVGGWGVDAAMLLPLFDRWPGEIHLISLNDALMSRCDSV
TEVADYLLERYPCPSVWAGWSQGAQVVMAAASRSFAQVSKAITLAGFPRF
VAGPQWPAGMAVDSFEAFRGQVSQNAGLAWRRFQQLLIHGCPDGSQARQE
LRPWLARGPSVSDLNLARGLEWLGSEDQRSLWSALAVPTLHLQASEDVVV
QCWEHTFDPSQVAKVVTVPGMTHWPRGQSLSRCQDEILRFVFGKEVQWTL
>9aqui-a8uy41 /F89/ Hydrogenivirga sp. 128-5-R1-1 Putative uncharacterized protein
MELLSPVFIHGWAFSSRVFNRCRGIKVELPGHGRNTEPYKNLESVVESLA
LSLPGRHDIVGWSLGGTLALMLAMKYPAKVNRLFLIGTSPYFGGAWSERN
LRAFKLRIKREGVGAFRKMAYPKSFEDRLSEETALRMLEDFIKTDLRCRL
PLLRKKTLIVHGERDVITPVKEALKLYNLVKGSKLIILPGGHFPAEDETG
LLSTLLKVGRDL
>9aqui-a8uzu7 /F89/ Hydrogenivirga sp. 128-5-R1-1 Putative uncharacterized protein
MNVFLHGWGFSKEIWKDFYNLDNSIFLDLPFHGELKKFSTENILENYIEY
INAFVKEPSVFIGWSLGASVSILFYLKYPEKVKKLILIGFSPKFKSESLG
HPPKYVKAFLLSLRKDFENTVYNFRVLSSDKKFENIPLPEKKGATKILNE
YINLDLTDDLKKITVPAVIIHGKKDKVVNYKVSYFVNQKIKNSELFLYPY
NHSPFYNNPDIIVNCI
>9bact-estC76.202 /F89/ uncultured bacterium. Lipolytic protein estC76-202
MRERGLYRETFGRGPDLVMVHGWGMHSGIWRDFAETLAEKVRVTLVDLPG
HGRSANIADFSAAGLADALLTIAPECAHWLGWSLGTLPVLHIADQCPNRV
KSTIVVAGNVRFTSDSTTGGTESGWPGVEPALLAQFASDLEANYAGTIRR
FLGLQTFGMEDAKGLVKELSARVAACEPPDPAALRGGLELLRQADLRGAW
RRMNVPSLVILGARDRLVPKSAGVSMRALNPRSELHVIGGAAHLPFLTHP
AETASLITEFIARHERR
>9bact-q3ymm4 /F89/ uncultured bacterium lipase/esterase
MHAEAERIAIGGLRLRHWPGQGRPRVFVHGWAMHGGLFAELIDALDPRPA
YALDLPGHGDNRDSAVPLEPDAVAAALAPLGTADWIGWSLGGLFALAAAS
AGQASGVALIASLPRFVAGADWPHGMPEATFAGFAADLARDWHGTVDRFL
ALEALGDADERALMQRLRLQVYAHGEPDPAALSAGLDLLHTRDARATLAE
VAASGVPIRLIGGRRDRLVSPAALAATAALHPAIRSQIIPGAAHAPFMTH
VAEVAAALG
>9bact-q6a3q9 /F89/ uncultured bacterium lip1 protein
MPQNTGNLSINVQGSGPALVLLHGWGLNQAIWHPIQAKLAAHFTVYCVDL
PGFGDSSWLPGNESFHHACTRVAEQLIRRIGHSFALAGWSMGGLIATQIA
LDFPTYVQRLITIASSPCFIAHEGEQWPGIKPTTLETFRYQLTTDYRKTL
ERFLAVQALGSPAARDEIKAMRVLLSERAEPQPEALVAGLRWLAQVDMRK
QLMALEVPLLRLYGKRDSLVPIATQEAIRPLLPHHLQDTVVTFQGSAHAP
FFTEPEQFVAALL
>9delt-q1nt00 /F89/ delta proteobacterium MLMS-1 methylase involved in ubiquinone/menaquinone biosynthesis-like
MLTPEPPAEDGPPLLFVPGWGFDGQVRELRPELVPCPAPTDFYDPFTLAD
ELAAWLDRRNIPTCRLLGWSLGGLVALDFARRYPQRLEGLTLLGVRAHWP
AAELETSRRELRRQPADFLRSFYRKVFLGYQAAYRRFQHQLEADYLDRAL
AGLDLLDRGLAFLATPATTLLPAAGGRLRCWHGRRDLLAPPAQRLQIPGT
PCQVLEHGGHALFLEPDIPLPQPHLRTNPRASPQPRPRASPRATVQQR
>9entr-b0m0h6 /F89/ Serratia sp. SES-01 Biotin synthesis protein BioH
MSALYWQTIGEGDRDLVLLHGWGLNAEVWHCMIERLTPHFRLHLVDLPGY
GRSLGFGPMSLEQMAETVMAAAPAKAWWLGWSLGGLVASQIALLQPQRVS
GLITVASSPCFAAQDDWPGIRPEVLSGFQHQLGQDFQRTVERFLALQTLG
TQSARQDARLLKSVVLNQPMPSVEVLNGGLEILRTADLRQPLAKLPLPLL
RVYGYLDGLVPRKVAGLLDVSWPNSPSIIIAKAAHAPFISQPDEFAEIIG
TFVAENGI
>9entr-b6xh89 /F89/ Providencia alcalifaciens DSM 30120 Biotin synthesis protein BioH
MKNDNEIDRKESVIMATLYWQTVGEGKQDIVLLHGWGLNAEVWQTIIPRV
ASQFRIHLVDLPGYGRSRDFSPMSVQSMADILWEQAPKNAIWLGWSLGGL
VASRIALDHSDEVKALITVASSPCFRAHEEWQGIKPEVLLNFEKMLSENF
QRTVERFLALQTLGTESAREDARTLKSVVLALPMPTVEVLNMGLESLRTE
DLREELTHLTVPFLRIYGYLDGLVPRKIVSKLDALYPHSSSIVMRHCAHA
PFVSHPDEFSEYLIEFFTQLDK
>9entr-c0auc8 /F89/ Proteus penneri ATCC 35198 Biotin synthesis protein BioH
MNKLYWQTIGEGKTDLVLLHGWGLNAEVWQSLIPRLSSHFTLHLVDLPGY
GRSQGFPALTLKEMAEIVFTKAPANAIWLGWSLGGLVASRVVLDNPNNVQ
ALITVASSPCFGAHDDWPGIKPEVLRGFEQQLNENFHRTVERFLALQTLG
TQSAREDMKALKSVVLEQPLPSVEVLNGGLEILRTEDLREELKMLSCPFI
RFYGYLDGLVPRKVAGLLDAIYPQSPSVIFRNAAHAPFISHPDEFSDALI
HACKE
>9entr-CarHBioH /F89/ Cedecea davisae pimeloyl-ACP methyl ester esterase BioH CarH
MNKLWWQTKGEGKIDLVLLHGWGLNAEVWHCIVKELGSQFRLHLVDLPGY
GRSQGFGALTLEEMAEVVLAQAPQQAIWLGWSLGGLVASQVALRHPERVR
GLITVASSPCFTAHDEWPGIKPDVLAGFQRQLSEDFQRTVERFLALQTLG
TETARQDARQLKAVVLEQPMPEVDVLNGGLEILKTVDLREEMETLTVPLL
RLYGYLDGLVPRKIAGLLDERYPQSGSAIFPKAAHAPFISHPAEFCEQVY
QFAKLVDE
>9entr-d1p0w3 /F89/ Providencia rustigianii DSM 4541 Biotin synthesis protein BioH
MAQLYWQTVGDGKQDLVLLHGWGLNAQVWQTLIPRIASQFRIHLVDLPGY
GRSQNFSPMNIQSMAETLWAQAPKNAIWLGWSLGGLVASRIALDHSKEVK
GLITVASSPCFGAEDNWAGIKPDVLLNFEKQLSADFQRTVERFLALQTLG
TESARDDARTLKSVVLAQPIPTVDVLNAGLESLRTEDLREELKNLAIPFL
RIYGYLDGLVPRKIVGILDEMYPESKSVMIRQSAHAPFISHPDEFSKYLI
EFSNQLDKP
>9entr-d2u2z8 /F89/ Arsenophonus nasoniae (son-killer infecting Nasonia vitripennis) Biotin synthesis protein BioH
MLLHGWGLNAEVWRTIEVGCGSHFRLHLVDLPGYGRSHLFPPMSLQQMAE
VIWQKAPKQAIWLGWSLGGLIASIIALNHQVEIAGLITVASTPCFSQQEN
WPGIKPMVLTGFEQQLQANFHRTVERFLALQTLGTKTAHEDIRLLKTVLL
KQPLPSVAVLNAGLEILRTTDLRQSLLTLNKPFLRIYGDLDGLVPRKVVP
IIDGWLPNSPSVIIKHAAHAPFISHPKQFIQLLVNFSSQLEK
>9gamm-a0y490 /F89/ Alteromonadales bacterium TW-7 hydrolase domain
MQKELVLLHGWGMNQGVWQLIQPELENLYAGEVRSLDLPGFGNSATTLPT
PYNLHDAAMQLSQQLKPHSILMGWSLGGLFALYIAKHWPEKVAKVILVAS
TPYFAEQGEWPGISEKVLTQFKDQLVNHREKTIERFLAIQAMGSESARDD
IKQLKQLLNQYSAPNSEALTAGLDILQNDDLRDLFATCPVKIMGVFGRLD
ALVPYKAIAKMSVLNTEFEYQVIDKASHAPFISHKNEFLSIVKSML
>9gamm-a3wj22 /F89/ Idiomarina baltica OS145 Biotin synthesis protein BioH
MSIAITRQGQGEDLVVLHGWGMNRHVWSLIKDELSKHFNIWLVDLPGFGD
SHEETLSNSVDSIADQLLSSLPQRFHILGWSMGGLIATSLATRHCQRVDK
LITVASSPYFLESSDWPGIKPRLMTQLETDLQNDFRKTVERFLSLQAMGS
KNAKQQVKQLKQWLFESPLASEETLLTGLKLLEKTDLRNTLKHIQAPMLR
MYGRLDGLVPISACQAIEPLVPQSTSYVFNDSAHAPFITEPELFIERLIS
FIKG
>9gamm-a3y9c0 /F89/ Marinomonas sp. MED121 BioH protein
MRYKLEQVSFGDPANQAIFLLPGWAMPKECFYELAHKLSQQYYVVLVNLP
GISTDVELIKGAKTGPNYDIDALTEQLILAAPKDAWWLGWSLGGMIASYV
AAHRASCVKGLITIASNPSFVRSEGWQWGMSLGDFEAFEDLIKHDPVVGL
KRFIALQSKGSRAATEVRKQLSHWVEPDACLPLALEAGLHLLKNLDVRRE
LEILDMPSLHLLGEKDVLVDSNWPKAIINNCVPIEYKVFENCAHQPFIED
LDQLYPHIENFLNAQ
>9gamm-a4ceu8 /F89/ Pseudoalteromonas tunicata D2 Putative enzyme in pimeloyl-CoA (Biotin) synthesis with alpha/beta-hydrolase domain
MGVKTIILESINHGKGEIKMQKQCVLLHGWGMNSNVWQQVLPQLHHDIPQ
VNFKALDLAGFGDNKALPSPYSLETIAAQIAQQLAPKTILMGWSLGGLVA
IYIAKHWPEKVAKVVLVASTPLFSEQHDWPGIKVKVLENFTEQLQQNSTR
TIERFLSIQALGSESAKDDIKALKIALAQSNPADEIALKQGLAMLLNDDL
REDFASLTQPVAGIFGRLDALVPIKAEQQMRALNSHFSTVVIEKASHAPF
ISHKAEFTSALETLL
>9gamm-a6fg15 /F89/ Moritella sp. PE36 Putative bioH protein
MSEIVVTESKNVSPCTTLYVDIVGDGPDLVLLHGWGLNGACWQSIVPLLS
QHYRLHLVDLPGFGFSHDSHVASGTLADITDALIKVAPANAVWLGWSLGG
LCATDFALQYPHRVSALVTVASSPKFMAASKVDDSATWPGIAEQVLAQFQ
QQLQQDLSQTINRFLAIQGMGSATAKQDIKQLKLLLAARPQPHEQALSNG
LTLLSTVDLRAQLATLTMPFYRCYGRLDSLVPQATVAWMDNYLPQSPSWI
FKASSHAPFISEPTLFVNKLQAFINHSL
>9gamm-a9cy57 /F89/ Shewanella benthica KT99 BioH protein
MDLPGFGYSSAIAGDIYDWLEALITRLPDKAIWVGWSLGGLLATLAALNY
PGRVRGLVTIASSPCFMAREEEKWPGIPPQVLSQFGESLHKDLGKTIERF
LAIQAMGSTTAKADIKQLKNLLLSRPLPDSRALVQGLNMLECVDLRPKLD
KINLPWLRIWGRLDRLVPRRVPPLMPLNDTIYQDIILPKASHAPFISHKD
EFLAGFVTWIEEISN
>9gamm-b4wya3 /F89/ Alcanivorax sp. DG881 Putative pimeloyl-BioC--CoA transferase BioH
MPKLIPFHNTYKATGVNDDEAQDIVLIHGWGLHAIVFDDIVPALLERFRV
TVVDLPGMGQSPMPNGDYTLDFLADEVLAIMPERAHVLGWSLGGLVALAM
AGKAAQRVQSVVTVATSPRFTTGEGWDTAMKPDILGKFAEMFDEDHEGTL
VRFLALNCKGSAAMREDTARLKEILYFCGLPAPKALRSGLDILREADMRT
VLPALDMPVLMVFGENDHIVPAAAMAASEPLIHHGRTALIEQVAHVAFLS
APETFTRAVYDFYREYRLVA
>9gamm-b5jtu3 /F89/ gamma proteobacterium HTCC5015 Carboxylesterase BioH
MDVACWQSVQAALQADFDVLPLALPELPSLSTGDTECLLDAWLQDLLARV
PRRAYWLGWSLGGMLVMALSRRYPDRLLGAAVVAAAPRFVEDEGWPGVPR
SVVEGFERQLCEAPEQLRRQFLALVAHGDRAARRALKPAVDGEVSLRQGL
HLLKSMDLRGAWNSPLLSGVLLSEVDGVLPPTLIAPMMSECGEKIRLTAA
CHAPMVSAPEIVAEFVRDCFCR
>9gamm-b7s223 /F89/ marine gamma proteobacterium HTCC2148 Biotin biosynthesis protein BioC, putative
MLPALRSWANITLLDLPCLAPGLASAPVSLNSLLEGIFTHSPERAVYMGW
SLGGQLALELATMQPDRVAALVTLCSTPCFLEQDGWPGMPAPTLQQFSEA
FVADPPAGLRRFDSLQAAGAARPRSLMRSLHALRNDQSSGYLEAGLDWLA
CLDQRSCCSELTQPQLHLYGDNDDLLAADLAQSMAKLLESVPRAVVGFIE
GASHVAPLEQGRAISDSLFHFLQNA
>9gamm-c0n6r0 /F89/ Methylophaga thiooxydans DMS010 Putative pimeloyl-BioC--CoA transferase BioH
MHSGVWHELAEGLAERFTLHLVDLPGHGQSDWQEGQFELPLLLSELEQKL
PDNAVWLGWSLGGLICLAMQQRYPKKVRKLSLMATTPKFVGCETWPCAMA
PSVFESFASNLHVDQQQTLQRFLMLQAKGAVQSREIIRELSEQLATQHTP
QPEALRQGLALLLQTDMRDALSQATCPLQLILGERDTLIPASMPDYAKKL
NPALDVTMIDGVGHAPFIAQPQRCQELIELFIDG
>9gamm-c6mzw5 /F89/ Legionella drancourtii LLAP12 Biotin synthesis protein BioH
MNIHIKTYGCGFPLVFFHGWGFDSQVWMPLVSQLAGNYQLILVDLPGFGH
SFMMDWSSFKTQLLNQLPPQFALVGWSMGGLFATRLALEKPERVTHLINI
TSSPRFLLDNDWPGVSQEVFTTFYQNLLKDSRATLEEFIALQVSKHNFEL
ALGHLPSSAGLASGLDILGTWDFRQQLKQFERPVCYMFGRLDPIVPVKTM
KAMQEHYPGFKYVYFNRAAHMPFLSHMDLFTSEMQEFIK
>9gamm-d1kc19 /F89/ uncultured SUP05 cluster bacterium Hydrolase
MLYSSTTGIGQDLVLLHGWGFNSELFNDLIDRYKNQYRITKIDLPGHGRS
DEVNGGLNEWCDEIIKILPNNPTLLGWSLGGLLAINIANKVSISKLILVA
STPNFVRTDNWEFGIGANNFEQFSDSLQLNLSKGLKRFVSLQTKDKTQIK
HLNQTIDNYPATTQALNQGLNILLKTNLIKTLESLSVEKEVILGKNDTLV
PNKIAKWYQQNNIKTQLLNTGHLPFLCDDFLL
>9gamm-q1mzv8 /F89/ Oceanobacter sp. RED65 bioh protein
MQIQHDEFHIREFGNPDNPSLFCIHGWASNSHVFEPLAKLFKDHFHFVCV
DLPGFGESKCEDAQQSYQLPYLIEGLLSVAPEKSAWLGWSLGGMLAVQAA
AKLQLEKSDRIEALVSMNANAKFIAHKSWKSGVPQPLFDGFMESIADVKT
TLRRFAALTVVGEQKDMLQSLKWLQQNTQVPAPTSDVLNASLKLLAQLDN
RATLKQLTLPTLHLLSTDDAIVPNGVSQELNKLNPMHPVSFVPNGSHASL
VAQPQSVANGILTFLEGLNA
>9gamm-q1yr00 /F89/ marine gamma proteobacterium HTCC2207 probable biotin synthesis protein bioc
MNAFIAAPSPVLSSNNPALTDYPCTGMRLYTQPLVLLHGWGMDSQIWAQL
PQQLRQFADVMTLDLPGFAQSPTVQNYSSAGLYQWMAELLPERCYLIGLS
LGGMLSCGFAARYPQRVAGLVTLSSNSHFVASEANPTALDKALYLGFLDN
YNQNEDQCLKRFAALQAQGDKQQRQLIRQLRSMQVCLDSHSGVQLLTLLG
DIDNQSGLTQLQCPALMLLGQGDALVPVASGARIASLNSKIEVNIIAGAG
HLPHLTQPETVIEKIKNFLARQLYALD
>9gamm-q1zel6 /F89/ Psychromonas sp. CNPT3 bioh protein
MSIEKVVACRISGVGEDLVLLHGWGTNSAIWQGVETSLAQYFRVYCIDLP
GFGKSSELSTYTLTSMLEAIIEVLPDHAIWCGWSLGGLLATYASYAYPHK
VRKLIQVCSALKFVSEDPLYGVEGAVFENFKENLKTDKNKTLKRFISLQA
QGPISSKKDIVVIKKSLQNSFIASDEALLSGLDLLQHTDLIECFATIKQP
CLSIFGAYDALIPEQGRLQMQAILKHSQQVVFEQSAHAPFISERDRFCHL
IKMF
>9gamm-q2bk53 /F89/ Oceanospirillum sp. MED92 putative biotin biosynthesis protein
MGLHVERVGGEGKPELVMLHGWGMNSSIWSGVVENLASNYSITLIDLPGL
GRSVSYPEPYTSDGVIQMLADAAPEKASWIGWSMGGQLAIQFADRYPERV
ERLVTIASNPCFVQKPDWRSAMDEETHNAFEISLSENVAKTLSRFAMLQT
QGAEAARDTLKQLKAALKVAEPSAPVESLGLLREDVRSQLSALKMPLLQM
FGEKDLLVPVSAALECDALTSRASIVYPGAGHLPFISHQAELVSDLTRFL
QEPLA
>9gamm-q2byf3 /F89/ Photobacterium sp. SKA34 putative bioh protein
MAVMLDWHNKGQGSDLVLIHGWGMNGAVWQDVIPVLAEHFTVHWCDLPGY
GYSGDVTAESLVEITQAVLARAPQKAAWLGWSLGGLVATQAALLAPERVT
QLMTVASSPSFMAREGWRGIKPDVLKNFQSQLASDFSLTVERFLALQAMG
SPTARQDIKNLKQAVLERPTPQPSALTLGLTLLETVDQRTELSLLTQPWL
RMYGRLDGLVPVKTETAIAKLCPQSLSYVFQSASHAPFISHPDEFIDVVR
QFISEDAVVS
>9neis-b9z5l8 /F89/ Lutiella nitroferrum 2002 Biotin synthesis protein BioH
MSLYIESLGRGPDVVMLHGWGLHGGVFSRVAERLDGRYCLHLVDLPGHGA
SASRHPFDADDIADLLAAQLPWPVHVVGWSLGGLLAQHWAARHPEQVKSL
ALIASSPRFVKQDGWPHAQEKKAIEGVGASLDSAFELTLERFLALQMLGA
PGARDTLKALREELFAHGRPQGLLPALELLLMADARALAPRIHCPVGLFF
GAKDAITPIGAGRWLAETLADATLYEFPQASHAPFLSHEEEFVARLAAHL
DQHA
>9prot-q0evs9 /F89/ Mariprofundus ferrooxydans PV-1 alpha/beta hydrolase fold protein
MTPLVFLHGWAQSRQIWYQQQRAFPQAHFLNLPGHGGAMAAPADAWLDLL
VAQLPDEPCALIGWSLGGMLALEIAHRFPERIAALGLIATTPRFRTGDAW
SCGCDEATFAAFHEAVASASPRALNRFFALMLHGDDLPRSRYNELARHAV
DRQNPATSSALSAGLALLASLDLRQSLALADMPVLLMHGEQDAIVPVAAG
RWLAEQLPGAQAHYADACGHAPFLSQPERFNTILKEWWQQ
>9psed-CE18 /F89/ Pseudomonas aestusnigri VGXO14 alpha/beta fold hydrolase
MNNLTLLPGWALAASNLLPLQQALHERLPDLTVQLAELPPRLQMSTLEPD
LTALAEALPAGWLAGWSLGGMLAVQLQRRFPERFFGVITIASNACFAARN
GWPHAMPVDTFKAFLADAREQPERILKRFSLLVTQGGENARELSKQLQWS
DADPLQRLNQLALLGVIDNRIPLQRCAQPVLHCLGGNDALVPAAVESDLL
ALNGNARVRMLPQGSHALPLEAPLWLAGEIAEWLEAQ
>9vibr-a6d4h9 /F89/ Vibrio shilonii AK1 Biotin synthesis protein BioH
MNSVGDNVSSASKVHWHSEGQGPDIVLLHGWGMNGAVWSKCSAELAQSFT
VHSVDLPGYGFSHDVEYQSLEQFCELLLADAPDQAIWLGWSLGGLVATHI
AHYYPQRISQLVTLASSPKFSEGEQWRGIKKDVLAAFTEQLTENFKLTIE
RFMALQAMGSPSARQDVKQLKEAVLSRPMPSQEALMLGLNWLDSLDLRQQ
LGELSMPVHRWYGRLDGLVPVRVAKQLDELTSGHQSHVFKDSSHAPFITE
QSGFIDKVQALVR
>9vibr-c9nll8 /F89/ Vibrio coralliilyticus ATCC BAA-450 Biotin synthesis protein BioH
MENVAQNEIKPTTPYWQSTGQGDDLVLVHGWGMNGAVWHQAVEQLSQHFR
VHVVDLPGFGHSHQLHFETMEELAQQVLHSAPDNAIWLGWSLGGLVATHI
AIHHPERITKLITVASSPKFSAEKRWRGIQPQVLSAFTEQLVDDFRVTIE
RFMALQAMGSPSARQDVKTLKQAVLSRPEPNPQSLLAGLQLLADVDYRQA
LLDVSVPTLRLYGRLDGLVPAKVATDVDTLMPTSESYMFGASSHAPFMTE
LNEFCQQVTRFSAGR
>accpu-c7rnx0 /F89/ Accumulibacter phosphatis (strain UW-1) Carboxylesterase
MTRVVGEGPDLALIHGWGLGSAVWEPLRPALSAHARVHLIDLPGYGEAAD
DSGDFTATAQTLIDALPNPVVLCGWSLGGMLAVRAAVLAPERVNGLVLVG
ATASFTQRGDWRAAQAPAVVDSFSASVRLQPEQTLQRFVTLLSQGDNQAR
AITRELLASLNRAPGPQIEALGRGLDWLREIDLRPLLPAVTARCLLVHGE
NDPLNPLAAARYLAETIANARLEVFGGAGHAPFLNDRERFVRLLDDFCHV
RPAP
>acif2-b7j3y8 /F89/ Acidithiobacillus ferrooxidans (strains ATCC 23270 / DSM 14882 / NCI 8455; ATCC 53993) (Ferrobacillus ferrooxidans (strain ATCC 23270)) (Leptospirillum ferrooxidans) BioH protein
MNWARQVSGRGRPLVLLHGWGMESRVFASWRSLLDTHFTCISYDLPGHGQ
TPCAPSGLAWSASLESLRQMLAQEAPKPLLLGWSLGGLLALGIALQHPEL
LAGLVLVSSSPAFCQRPDWSPAIPAATLEDFAQRLRVDPQGTRRRFLALQ
VLNDPQGRRVLEGLSTSWPMPDQACLADGLGLLREVDLRSQLSRVPMPVH
IVHGRQDRIVPVGAGEYLHQHLTGSRFTLLEQAGHAPFLSHPEACANALL
ETWG
>acijo-d0sb61 /F89/ Acinetobacter johnsonii. Uncharacterized protein
MKFTVLESALNQRILLITGWGGGTKLLQPLAHALQHKGHSVELINIFNGL
DTQALQQYTEQAKDFDVIIGWSLGGQLATLLVEAVEQQYQQQKVLITLAS
NPCFVAHENWATAMSPATFQSFKQSFEADAIATLKKFGFMVCQGTATTKQ
DFLQLQSLLQPQSLDLLKQGLNCLEYLNTVEILQNYTGHQLHLLAKQDFL
VSYKVLDNLKTLGAIFLDAMLLTGSHGLPVFHVYEVTDKICQYLQKMD
>aerhh-a0kf11 /F89/ Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) putative pimeloyl-bioc--coa transferase bioh
MSVSVERFGQGPDLVLLHGWGMNGAVWHGIVPALASRYRVHLVDLPGFGN
SPLAGEVEYSLPWLAEEVAAILPEQCHLLGWSLGGLVASQLALSHPERLH
SLITVASSPCFMARDEWPGIAPKVLAGFNQMLAGDFKQTIERFLAIQAMG
SEHARDDIRQLRHWLAERPAPQLAALEAGLGLLAEVDLRDELTPLSLPWL
RVYGRLDSLVPKASIPLLDERYPSSRSVVLEKASHAPFISHPQQFIEIIE
HFVG
>aers4-bioh /F89/ Aeromonas salmonicida (strain A449)Biotin synthesis protein BioH
MSVSVERFGQGPDLVLLHGWGMNGAVWHGIAQQLAAHYRLHLVDLPGFGN
SPLREGSDYSLPWLAEQIAIVLPQKCHLLGWSLGGLVASQLALTQPERLH
SLITVASSPCFMARDEWPGIAPKVLTGFNQMLAGDFRQTIERFLAIQAMG
SEHARDDIRQLRHWLAERPAPQFAALEAGLGLLADVDLRDELLQLSLPWL
RVYGRLDSLVPKASIALLDERYPASHSVVLEKASHAPFISHPQQFVEIVR
YFVG
>alcbs-q0vmd2 /F89/ Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) biotin biosynthesis protein bioh
MPRLIPFHNTYRATGVDDAQAQDIVLIHGWGLHAIVFDDIVPALLAHFRV
TVVDLPGMGQSPLPNDDYSLDFLAEQVLAIMPQKAHLLGWSLGGLVALAM
AEKAPERVQSVVTVATSPRFTAADDWAPAMKPEILAKFAEMFNEDNEGTL
VRFLALNCKGSAAMREDTARLKQILYFCGLPAPRALRGGLNILRDSDLRE
SLTALSMPVLMVFGEHDHIVPAAVMAAVEPLIGNGRTALIEQVAHVPFLS
TPDTFTQAVYDFYRDYQLVR
>alheh-q0a5w3 /F89/ Alkalilimnicola ehrlichei (strain MLHE-1) alpha/beta hydrolase fold
MMRAVTEGRGPEGLVLVHGWGFDHRVFDPWLPRLTQRWRVTRTDLPGHGG
SAPLPADAGLEAWADAVRLAVPEDAIWVGWSLGALPLLAAAARGARPRAL
LLLAATPCFCQRDGWPYGLLREELDAMIGGLAEDARRTLRGFHALLGRAG
AGDREALRPWRRRGPGPATALEPGLSLLRDTDLRGRLAAIDRPTTWLAGG
RDPLVPDGAAKEAARAMPRARMAYHPEAGHLPFLTHPEWVAGHLHLLSQQ
CRP
>alisl-bioh /F89/ Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain LFI1238)) Biotin synthesis protein BioH
MTTSLYWQTEGEGSDLVLIHGWGMNGAVWQPIVEKLSSQYRVHTVDLSGY
GYSAELGSADFDEMVAQVLAQAPEKSAWLGWSLGGLIATQAALTAPDRVS
QLITVASSPRFAAEKGWRGIKSAVLSQFTEQLKEDFTLTVERFMTLQAMG
SPNAKQDIKQVKRAVLSRPAPNPSALATGLTILADIDLRESLSQLTMPVC
RMYGRLDGLVPIKVAHDMDAFIPHSTKVVFEQASHAPFISHSDEFITELH
RFLQPEDEFLI
>allvd-d3rnx1 /F89/ Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / D) (Chromatium vinosum) Biotin synthesis protein BioH
MSNQSAPPHTPTPETTADLVLLHGWGMNSAIWNGVPEPTWNGLTQHRIDL
PGHGDSPFPTGRDDLWGWAEACLDAAPERAVWVGWSLGGLIALAAALHAP
KRVAGLILLTATPRFTQATDWTPAMPEATLAQFHDGLLADPSGTLNRFLA
LQTRGSDTARETLRTLKQELAARPEPKPAALALGLDLLREEDLRPQLPDI
RCPTLWLFGQHDTLVPARVAERIELLMPEARVETIAGAAHAPHISHPHET
GRAIRTFLDAL
>anad2-b8j7l6 /F89/ Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258) Anaeromyxobacter sp. (strain K) Alpha/beta hydrolase fold protein
MPLLVTDSGVRLAYADRGAGAPLVLVHGWSLSSAAFDDLAVRLPGRRLVT
PDLRGHGGSGAAPFALEDLGRDLALLLDRLDLRGAVLAGWSLGAQAALAA
LPAVRARLAGLVLISGTPRFTLCDGWPHGLPAQALEVLAHRVRREPARAA
ARFFDGMFAPGELDPAARARTGALRAAIPSPGSAAALAGLDVLAAADLRP
TLAGVGVPALVIHGTADPICPPGAGRALAAGIPGARLALLPGAGHAPHLT
RPDEVAALLQAFPAGAGAVAA
>anade-q2ifz2 /F89/ Anaeromyxobacter dehalogenans (strain 2CP-C) alpha/beta hydrolase fold-1 precursor
MTRRSSLLSCASRPAMPLLLTDSGVRLAYADRGAGAPLVLVHGWSLSSAA
FDGLAARLPGRRLIMPDLRGHGGSDPAAFALEDLGRDLALLLDRLGLEGA
VLAGWSLGAQAALAALPAVRRRLAGLVLISGTPRFTIGDGWPHGQPAQAL
EVLAHRVRRDPARAAARFFDGMFAPGELDGPAAPRARALRAAIPAPSAAA
ALAGLAALAAADLRAGLAAIDLPALVIHGTADPICPPGAGRALAAGIPGA
RLALLPGAGHAPHLTRPDEVAALLRAFPAAAGVVAA
>anadf-a7hh38 /F89/ Anaeromyxobacter sp. (strain Fw109-5) Alpha/beta hydrolase fold
MPPFLDPAGLALHCEDQGRGPALVVVHGWSLSGRWLVDALPPALLAGRRV
IAPDLRGHGRSADGAPFRLAELAEDLVTAFDAAGIDGALLLGWSLGGQVA
LAALPRLRGRVAGLALVSATARFTEGEGWPHGVPARTLAALARQVERDPA
RATARFHDGMFLPGELDAEAASRAAALRDRAPVPSRAALRAGLDVLGEAD
LRGALSDVDVPALVVHGEGDPVCAPAAGRALAASLPRAELALLAGAGHAP
FLSRPHAFAGALSPLLAACA
>anofw-b7ghw8 /F89/ Anoxybacillus flavithermus (strain DSM 21510 / WK1) Carboxylesterase bioH (Biotin synthesis protein bioH)
MNILLLPGWGMKGDVFSPLIHALQPSHVTVVAWEHMHDVNHFLAKAKDAL
TVPSIVIGWSLGSLVALQLAMHEHVQALVCIGGTSRFTMTDDYPIGWHAR
VVERMKTQLMRQPEKTIQSFIDMLWGEEEAQPFHYMHHHIPDLLLGLDYL
LTTDVRDQLQQIDVPLLLIHGERDRICPPQAARYIYERTNRCTFTLMPNV
GHAPHVTQPSTCAHYIQTWLGGREND
>aquae-aq2138 /F89/ Aquifex aeolicus aq_2138 gene
MLKNPLFIHGWAFSSKVFNDFHGIKYDLPGHGKNKNPYESIEKVVEEIGK
IATSKHDVVGWSLGGSLALLFAYRYPEKVNRLILIGTTPHFKGAWSEKNI
RAMKLLIKKKGIKAFRELAYGKFEDFFDEEQGMRFLEDYVNLNLYTVLPY
IKKEVYLIHGVSDRIVPYSEAYKLHRALKCSKLILLGGGHFPVRNEEHLR
KAILKGY
>aroae-q5nzf6 /F89/ Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) bioh, catalyzes some early step in biotin biosynthesis ne2298
MNRPDLVLLHGWGLGPQVWSALTPYLPAGLRVRTPALPGHGGTPARGPTL
EAWSDALLPELPDDAVVCGWSLGGLVALDLARRHPHKVARLVLIGTSPCF
VTRPENAAAPWPYGLAASTVTGFIDDFAHDPAATLRRFVALQALGDARRR
TVSNALNAALANLEQCRPAALGAGLELLADTDWRAALDDVRQPVQLIHGA
GDALMPLAAAEWLATRLPDARLARFDDCGHAPFLSHPEDCAVLIEDVVRG
>azosb-a1k6q2 /F89/ Azoarcus sp. (strain BH72) bioh protein
MVEIGMPSLPPLVLLHGWGMTPAVWDGLAPALRERFAVSAPPLPCHPGSE
VTTGALPAWADAIAGGLPDDALVCGWSLGAQLAMTLALRHPHKVRRLLLV
GATPCFVAAPGWGAALDAATVTAFVEGFRASPAPTLRRFLSLQVQGEARR
KPVLQALGATAVAADALEAGDAAALAAALDVLVSTDLRALAGRITAPTLL
VHGDGDALMPLDAAHWLAEALPHARLEVFADSGHAPFLSDPERFVALLGA
LGDA
>azovd-c1dkj0 /F89/ Azotobacter vinelandii (strain DJ / ATCC BAA-1303) Biotin biosynthesis protein BioH
MTRLILLPGWGLGRAALEPLAGALRERGLDVGLAGLPALDESDPEAWLAE
LDARLPQGAWLGGWSLGGMLATALAARRGEGCRGLLTLASNARFVAGADW
PHAMPPDIFAVFRNGCAQDSVAILKRFALLCCQGCTEARSLSRQLNQGIP
AEETAQRLAGLEVLAALDNRAALVAFAGLQLHLLAEADALVPVAAAEPLQ
ALLSRGVVERVAGTGHAFVLERPQALAARLAAFIREAGDD
>bacan-BA4338 /F89/ Bacillus anthracis, Bacillus thuringiensis, Bacillus cereus, bioh protein, putative
MKELKIIFIPGWGMEENIWDLVLPHFKGYSVQCIDWRNVKEQSEFAGRII
DVAKDENVILVGWSLGALAAIQAYKKIKAKGIVLIGGTAKFTNASDYSNG
WNTLHVERLKRNLARRKEDTLKRFYENMFTKDELKENKSFEDIVKHFKGD
SIQSLQFGLDYLIETDMREALKEINVPILLIHGERDVICPLSAACSMAEN
ETAKLKVVSEAGHALCVTNFEYCVNEIIQFVEGIRHDQQNVTTKTV
>bacc1-q731i0 /F89/ Bacillus cereus (strain ATCC 10987) bioh protein, putative
MKELKIIFIPGWGMEEGVWTLVLPYFKEYSVQCINWRNVKEQSEFAGRII
DVAKDENVILVGWSLGALAAVQAHKKIQTKGIVLIGGTPKFTNTSDYTSG
WNALHVERLKKNVARKKEDTLKRFYENMFTKDELKENTSFEEIALNFKGD
SIQSLQLGLDYLIETDMRNELIDVKVPLLLLHGEQDVICPLSAAHSMTEN
ANAKLKVVSEAGHALCVTNFEYCANEIIQFVEGIRHDQQNVTTKTI
>bacce-BC4116 /F89/ Bacillus cereus, Bacillus thuringiensis, bioh protein
MNELKIIFIPGWGMEENIWDLVLPYFKGYSVQCIDWRNVKERSEFAERII
DVAHNDNVILVGWSLGALAAVEAYKKIQAKGIVLIGGTAKFTNTSDYSNG
WNALHVERLKRNLARRKEDTLKRFYENMFTKDELKENKNFEDIVDRFKGD
SIQSLQLGLDYLIETDMREELKEIKVPILLIHGEQDVICPLSAARSMTEN
SSSELKVVSEAGHALCVMNFEYCANEIIQFVEGIRHDQQNVTTKTV
>bacce-c2pjt4 /F89/ Bacillus cereus MM3 Biotin biosynthesis protein
MEEGVWTLVLPYFKGYSVQCINWRNVKEQSEFAGRIIDVAKDENVILVGW
SLGALAAVQAHKKVKAKGIVLIGGTAKFTSTNDYTSGWNTLHVERLKKNL
VRKKEDTLKRFYENMFTKDELKENKRFEDMIKRFKGDSIQSLQLGLEYLI
EADMREELKEIKVPILLIHGEQDVICPLSAARSMAENETATLKVVSEAGH
ALCVTNFEYCGNEIIQFVEGIRHDQQNVTSKTV
>bacce-c2qxu3 /F89/ Bacillus cereus ATCC 4342 Biotin biosynthesis protein
MEGDIWDLVLPHLKEYPVQCIDWRNVKEQSEFADRIIDVAQDDNVILVGW
SLGALAAIQAYKKIKAKGIVLIGGTAKFTNASDYSNGWNALHVERLKKNV
ARKKEDTLKRFYENMFTKNELKENKRFEDMIKRFKGDSIQSLLLGLDYLI
ETDMREELKEVKGPILLIHGERDVICPLSAARSIAVNETAMLKVVSEAGH
ALCVTNFEYCANEIIQFVEGIRHDQQNVTTKTV
>bacce-c2u276 /F89/ Bacillus cereus (strains Rock1-3; Rock3-28; Rock3-29; Rock4-18; R309803) Biotin biosynthesis protein
MEENVWDLVLPYFKEYPVQCIDWRNVKEIGEFAERIIDVAHDENVILVGW
SLGALAAIQAYKKIKAKGIVLIGGTAKFTNTSDYTSGWNSLHVERLKKNL
VRKKEDTLKRFYENMFTKDELKENKCFEDIVKHFKGDSIQSLQLGLDYLI
ETDMRGELKEIQAPILLIHGEQDVICPLSAAHSMADNTNVTLKVVSEAGH
ALCIMNLEYCANEVIQFVEGIRHDQQNVTAKTV
>bacce-c2wbq5 /F89/ Bacillus cereus Rock3-44 Biotin biosynthesis protein
MEKQVWDPLLPYFQEYSVRHVEWRDVKEITDFAKRIEEAAKGKEVVLIGW
SLGALAALQVCDRVRTKGMVLIGSTAKFTVDENYESGWKSPFVERMKRSL
VKRKDDTLERFYKSMFTKQELKESEQFEGIVARFQGDSIESLQLGLDYLI
EMDMRSQLQDVKTPILLLHGEQDTICPLSAARYIQENTIGTLKVRNGAGH
ALCVTDFEYCANEIIRFVEGIQNDQQNVITKTI
>bacce-c2yw57 /F89/ Bacillus cereus AH1271 Biotin biosynthesis protein
MEEGVWTLVLPYFKGYSVQCINWRNVREQSEFAGRIIDVAKDENVILVGW
SLGALAAVQVHKKIKAKGIVLIGGTAKFTNTSDYTSGWNALHVERLKKNV
ARKKKDTLKRFYENMFTKDELKENKRFEDMIKRFKGDSIQSLQLGLEYLI
EADMREELKEVKVPILLIHGEQDVICPLSAARSMAENETATLKVVSEAGH
ALCVTNFEYCGNEIIQFVEGIRNDQQNVTTKTV
>bacce-c2zcf9 /F89/ Bacillus cereus (strains AH1272; AH1273; AH621; BDRD-ST196; AH603) Biotin biosynthesis protein
MEEGVWTLVLPYFKGYSVQCIDWRNVKEQSEFAGRIIDVAQDENVILVGW
SLGALAAVQAYKKVKAKGMVLIGGTAKFTNTSDYTSGWNSLHVERMKKNL
TRKKEDTLKRFYENMFTKSELKENTNFEEIALKFKGDSIQSLQLGLDYLI
GTDMRNELTSVKVPLLLLHGEQDVICPLSAAHSMTENTNATLKVVSEAGH
ALCVTNFEYCANEIIQFVEGIRHDQQNVTAKTV
>baccn-a7gse0 /F89/ Bacillus cereus subsp. cytotoxis (strain NVH 391-98) Carboxylesterase
MKQLKLIFIPGWGMEKQVWSPILSLLQESFAEYIEWHDVKEINEFAKRVE
KAAEGYDVILIGWSLGALVALEVCNNVKTKGMILISSTAKFTVDERYKHG
WKPSFVERMKRNIKKRKNETLSRFYISMFAEEESAVKESFENMIKEFQGD
STESLQTGLDYLMRADMRERLKDVNVPMLLLHGEQDSICPLPAAHYIKEK
TNATLKVIHQAGHAICITNFEYCANEINKFIEGIRNDQ
>bacha-BH3908 /F89/ Bacillus halodurans hypothetical protein bh3908
MNVLWIPGWSIPFDRWKELCSPFQKAELEGMFIDFRACQRREDFLQLVLD
TIDGHQGEWLLAGWSMGSMIAIEAATLRKARVKGLFLLSSGLQFSQSDHH
PGGIPLAVIRHMSRQLKRNRTDTLTSFYEQMFSESEKSHGLDQAFLQTLE
AGDPFYHWQNESLIAGLDYLANVQLLQGWPTVSVPITWIHGSDDTICPSP
ASGLFSPSKRLIIVEGAGHVPFYTQDSVVINAWEELLGNVY
>bacmy-c3aq75 /F89/ Bacillus mycoides (strains Rock1-4; Rock3-17) Bacillus pseudomycoides DSM 12442 Biotin biosynthesis protein
MKQPELIFIPGWGMEKQVWDLLLPYFQEYSVWHVEWRGVKELSEFAERVA
EAARGQDVILIGWSLGALAALQACDRVWVKGMILIGGTAKFTVDENYESG
WKLPFVERMKRSLVKRKDHTLERFYKSMFTKQEIKDSEQFEDIAERFQGD
FIESLQLGLDYLIEMDMRSQLKHVKMPVLLLHGEQDAICPLSAARYIQEN
TNGALKVINGAGHALCVTDSEYCANEIIQFVEGIQNDQQNVITKTI
>bactu-c3c7d6 /F89/ Bacillus thuringiensis serovar tochigiensis BGSC 4Y1 Biotin biosynthesis protein
MEENIWDLVLPHLKEYPVQCIDWRNVKEQSEFADRIIDVAQDDNVILVGW
SLGALAAIQAYKKIKAKGIVLIGGTAKFTNASDYSNGWNALHVERLKKNV
ARKKEDTLKRFYENMFTKNELKENKRFEDMIKRFKGDSIQSLLLGLDYLI
ETDMREELKEVKVPILLIHGERDVICPLSAARSMAVNETAMLKVVSEAGH
ALCVTNFEYCANEIIQFVEGIRHDQQNVTTKTV
>bacwk-a9vg55 /F89/ Bacillus weihenstephanensis (strain KBAB4) Bacillus mycoides DSM 2048 Alpha/beta hydrolase fold
MKELKLIFIPGWGMEEGVWTLVLPYFKGYSVQCIDWRNVKEQSEFAGRII
DVAQDENVILVGWSLGALAAVQAYKKIKTQGMVLIGGTAKFTNTSDYTSG
WNSLHVERMKKNLTRKKEDTLKRFYENMFTKSELRENTSFEEIAQKFKGD
SIQSLQLGLDYLIETDMRNEVIDMKAPLLLLHGEQDVICPLSAAHSMANN
TNANLKVVSGAGHALCVTNFEYCANEIIQFVEGIRHDQQNVTAKTV
>bauch-q1lsz2 /F89/ Baumannia cicadellinicola (subsp. Homalodisca coagulata) bioh protein
MSRSSKKKLVLLHGWGFTTNVWSCIEPQLSSHFYIYNIELPGYGNLANYA
NLTVTQMANILVTKIPDKTLLLGWSLGGLVATKIAQLWPEKILGLITVAS
SPCFSSTAGWPGIKPKFFYDFFNKLNTNIIHTINNFIVLQTMNTNSSYSD
TRWLKKQFFSQKIPSIHVLNAGLMLLFKCDLRYVLPTIKLPLLRLYGNLD
PLIPEKSIQIIDKLCLSQSNSLSITFYGAAHVPFLSHARIFCRQLFFFSS
LIK
>bora1-q2kxn8 /F89/ Bordetella avium (strain 197N) putative biotin biosynthesis protein
MTRPTLYFVHGWACDARFWDSLRARLHDWPQTVADAGYFGTPAETPPPGP
VVAIGHSLGGMKLLADPPAHCQALILINSFGRFGAGQGFTQGVAPRLLDR
MRTQLRARPQAVLKDFRLRAANGRTLPAAQGVPDIQRLDTDLLRLRDENR
LTELHHWARPLLSLGAGADAILPLDAQAPATHFFPDGDHMLPLSDPDGCA
QAILTFLKALPA
>brebn-c0z788 /F89/ Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) Pimeloyl-CoA synthesis protein
MRKVMLWLTGWGMPDCSWDAVRSQFPSYQHIIPTYSDVTDSSQFYERVVE
EVRSLAAQELIVVGWSMGGMLGIRLAAQYPVSGLVLIGTTARFICERHDL
RAGWHPVVLQRMKRQLSVARERVMDAFVEQMLTPGEREQTGLYVRLDSQK
WSTTALIAGLTYLEEEDCRPFLSSLTTPTLVIQGTEDAICSLAAGEELAG
SLSGANFVQIPDCGHAPHVFVPEVVGDSLKRMVEQLAEEGNQQPI
>bucap-BIOH /F89/ Buchnera aphidicola (subsp. Baizongia pistaciae) putative biotin biosynthesis protein
MNKKLHWKSLGTGTTNLILIHGWGVNSKIWSILVQSQLYQHFKLHFVDLP
GFGHSNQLLPMTLNDTAELLSVYIPKNSILLGWSMGGLIASKIALNYPQK
IKGIISVCSSPCFIVRPNWPGIPKKIFLKFYNKLNINFDRTISEFITLQS
HNTNYLEIKNLKQQILSQPYPTIYTLKKNLETIFKTDLRTKIKKLKIPML
RIYGSLDTFVPKKIREILDILWPKTKSITIAHASHIPFVSHQKEFYESII
NFKNYLNTLKITCQK
>buccc-q056z0 /F89/ Buchnera aphidicola subsp. Cinara cedri Carboxylesterase
MNQKKKINLFTIEKGKIHLVFFHGWGLNSLIWKKIIPILKKKFTLYFLDF
PGYGKNIDFPIMNFNQLSDYLFKKIKKKVILIGWSLGGQFAHYLSFKYPN
FILAVIYITYTPFFMKKKRKKKKIFKKIKNDIILNYKKFLYDFINLHILY
KKKKNLLYFKKKFSFLKKYPNPKKEAIEIGYKWLTKIDQRKKILSKNIPT
LKIYGELDNLISIRIYKKSNNLNNLNKIKKNYYYIIPKARHAPFLSHPKI
FCKIINKFIKKL
>celju-b3pi89 /F89/ Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp cellulosa) Biotin biosynthesis protein BioC
MTRPVLVLVHGWGCDSRTWQPVLDGLRELVPVQLVDLPGFGNTPALETFS
LPAVLAAIESQLPERCVLLGWSLGAMLAVQLAARLPQQVLGVISLAANAR
FVASDDYPHAMAPDVNRQFNSRFAEQPQAALKMFTGLLAQGDVQERALLK
QLRTQVPDAINHNWAQALQLLAELDNRAALVQLSQPLLHLLAEQDALVPI
AAAESLRGLNSQHQIHVIAGSAHAVHWSQPQQLISAVQDF
>chrsd-q1qyd7 /F89/ Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIM 13768) alpha/beta hydrolase
MSDSATNTLVLLSGWGCDARLWQALDDHWPAGLEVMTPDWPGYGARTALA
DPASLEALADAMVDDLPPDAIWVGWSLGGLLAAALLDRLPTPRALVLLGM
GERFPHPEGVSPTALARFRQAFRRDPVATHAHFMRWQLGGEPSPRAAHRR
LRTLLGDEINADAATLAAGLAHLAEIDNTRRLATPPCPVHRLAGEDDPLL
APTVRERADYRLPGAGHCPPISQPMRLTRALAAIAVAPTRSLAEASLETM
P
>chrvi-BIOH /F89/ Chromobacterium violaceum bioh protein
MLHGWGLHGGVFARVAEQLATRFCVHLVDLPGHGASPALPRFDADAVADL
LAAHFPLPAQVVGWSLGGLIAQHWAARHPDKVKSLALVATSPRFVRDETW
PHAQARASIEAVAQSLDGAFEQTLERFLALQMMGAPSARDTLKALRGELF
SHGRPQGLLPALGLLLEADARALAGRIQCPAALFYGARDAITPIGAGRWL
AESLPDAVLYEFPQASHAPFLSHEQDFVRALAEHLETQA
>citk8-bioh /F89/ Citrobacter koseri, Citrobacter rodentium, Citrobacter freundii, Enterobacter sp. Citrobacter sp., Citrobacter youngae, Biotin synthesis protein BioH
MNDIWWQTEGQGNCHLVLLHGWGLNAEVWNCIREELSAHFTLHLVDLPGF
GRSQGFGAMSLEQMAKHVLKQAPDKAVWLGWSLGGLVASQVALTHPERVQ
ALVTVASSPCFSAREAWPGIKPDILAGFQQQLSEDFQRTVERFLALQTLG
TETARQDARTLKSAVLALPMPEVAVLNGGLEILKTADLREPLKSLTMPFL
RLYGYLDGLVPRKVVPMLDAAWPESESQVFAKAAHAPFISHPGEFCQALM
ALKQKI
>clotm-d1nkn2 /F89/ Clostridium thermocellum (strains JW20; ATCC 27405 / DSM 1237; DSM 2360) Pimeloyl-CoA synthesis (Biotin biosynthesis)
MLTGEDNGLEKQKLVMMPGWSMDSSVWKPVVAALSEYFQLIFCEWHGITG
MEGYTERVCKLIEKEKDKLCLLGWSLGSLLAIDAAGKYKDRVEKLVLVGG
TARFTRDKETGYFCGWHKSAVKKMKEAIKVHREKTMDSFYSSLFSSKEQE
SKEYVALFKVDIDTNTASFKELEAGLDFLLAADMRMQLESIKADTLIIHG
EMDSICPKEAALYMAQRMKNKAQVFIMEGIGHVPFYSLPEEFTRLILEFM
KQGDKSDR
>colp3-q48ac9 /F89/ Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) bioh protein
MAKSLTFSTFSPNNTLKKNVIPIVLLHGWGLNSGVWQPLLELFHRNDESI
YQLITIDLPGFGINSAVDIKPYSLANICHHIEQVIDQPAIYLGWSLGGLI
ATEMSLKYPEKVLASITVASSPYFVEQPTDNWPGIKENVLESFHKQLAQD
TAKTISGFLKIQAMGSPHIRQDLKLITQLVMAHTLPSQQTLADSLALLSN
SDLRLHLSKIKQPLLRLYGHNDSLVPKEVMEKISYLAPNSDQHLFADASH
APFISHLDDFYQVLVVWLDSHFN
>coxbn-a9kg73 /F89/ Coxiella burnetii (strains Dugway 5J108-111; RSA 331 / Henzerling II; CbuG_Q212; RSA 334; CbuK_Q154) Carboxylesterase
MLSEPIVFISGWGFHASLLKENPYLEKKIILIDLPRLSELTLESVVNYLL
PQIPDKSIILGWSLGGLIGIQLASQFPGKVKKLALISSSPRLAADANWPG
INKKDVERFLILAKKDFNNLFDYFLSLVNYPNKDLAFKNQLIKNAVDFER
DKNCLRNYLSILFETDLREEYSCLKIPLFHLFGEKDAIYKVDSKALAGLN
KHSEIHSLPKAGHLPFLTHAREFYDRLMRFVNDG
>coxbu-BIOH /F89/ Coxiella burnetii bioh protein
MLSEPIVFISGWGFHASLLKENPYLEKKIILIDLPRLSELTLESVVNYLL
PQIPDKSIILGWSLGGLIGIQLASQFPGKVKKLALISSSPRLAADANWPG
INKKDVERFLILAKKDFNNLFDYFLSLVNYPNKDLAFKNQLIKNAVDFER
DKNCLRNYLSILFETDLREEYSCLKIPLFHLFGEKDAIYKVDSKALAGLN
KHSEIHSLPKAGHLPFLTHAREFYDRLMRFVNDG
>decar-q47c03 /F89/ Dechloromonas aromatica (strain RCB) alpha/beta hydrolase fold:thioesterase precursor
MSAPLVFLPGWCLGRSPLQAVVEALNGQIIDLPGYGNAPLITDFYAAADD
IAARLQPGTTLAGWSLGAQLALAVAARHPDKVGKLILVAGTTSFVQRDGW
PNAMPPDMLTEFAAGIAADVEAMLPRFVGGFNRGDARAKTVTLELLKLAD
PRPSDAVLATGLNWLRDIDLRDIAPQVKAPTLLIHGGADPLMPLGAAKAL
TALIPGASLEAFADCAHAPFISRPDEFLATVRRFLND
>dicd5-d2by62 /F89/ Dickeya dadantii (strain Ech586) Biotin synthesis protein BioH
MESLHWYTQGEGACELVMLHGWGMNSKVWNNIVVRLAPHFRLHCVDLPGY
GQSQGFPAMSLEEMTETVLASAPARAVWLGWSLGGLVASLAAIRAPERVS
ALITVASSPRFEAADEWPGIKPLVLSGFQQLLNEDFSGTIERFLALQTLG
TESARKDARLLKAVVTTQPSPTVEVLDGGLEILRRVDLRQELAGLTTPFL
RVYGALDGLVPRKVAALMDEQYPHSTSVVIPKASHAPFISHPEVFVEHVV
GFVGENLLV
>dicdc-c6c7y9 /F89/ Dickeya dadantii (strain Ech703) Biotin synthesis protein BioH
MESLHWQTEGSGKCELVLLHGWGMNAQVWNSIVVRLAPHFRLHRVDLPGY
GRSQGFGALSLEEMTTTVLAGAPARAVWLGWSLGGLVASLAALRAPERVS
ALVTVASSPCFEARDEWPGIKPLVLSGFQQLLNEDFAGTIERFLALQTLG
TESARKDARLLKSVVTEQPSPTAAVLSGGLEILRRADLRQELAGLTTPFL
RLYGALDGLVPRKVAMLMDEQFPHSTSVVMPKASHAPFISHPEPFVEHLV
AFARQHGER
>dicze-c6cgi6 /F89/ Dickeya zeae (strain Ech1591) Biotin synthesis protein BioH
MESLYWHTEGEGTCELVMLHGWGMNSQVWNSIVMRLAPHFRLHRVDLPGY
GQSQGFGVMSLADMAQQVLAQAPARAVWLGWSLGGLVASQAALSAPERVS
ALITLASSPCFEERDGWPGIRPQVLSGFQQLLSDDFFGTIERFLALQTLG
TENARKDARSLKAALSGQPAPTTEVLNAGLGILRDTDLREPLSTLTMPFL
RLYGALDGLVPRKVAALMDEQYPHSTSVVIPKAAHAPFISHPEVFVEHVV
GFVGKISTFDK
>ecoli-bioh /F89/ 
Escherichia coli, Escherichia fergusonii, Escherichia albertii, Escherichia sp., biotin biosynthesis bioh bioH2
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGF
GRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQ
ALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMG
TETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFL
RLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPAEFCHLLV
ALKQRV
>edwi9-bioh /F89/ Edwardsiella ictaluri (strain 93-146) Biotin synthesis protein BioH
MSALFWHTCGAGKRDLVLLHGWGLNAEVWRSIVPQLSAQFRLHLVDLPGY
GRSGGDTPYSLAEMTQRVLAQAPERALWLGWSLGGLVATQAALYHPQRVS
GLITVASSPCFTAQMAWPGIRSDVLYHFQSQLRDDFQRTVERFLALQTLG
ADSARQDTRALKSVVLAQPMPSAAVLNAGLSLLRETDLRPQLATLALPWL
RFYGALDGLVPRRVAPLVDALSPCGRSLIIPGAAHAPFISHPEPFCAALC
EFADGRSV
>edwte-d0zg19 /F89/ Edwardsiella tarda (strain EIB202) Biotin synthesis protein BioH
MSALFWHTCGAGKRDLVLLHGWGLNAEVWRCIVPLLSAQFRLHLVDLPGY
GRSGGDTPYSLAEMTQRVLAQAPARALWLGWSLGGLVATQAALHHPQRVS
GLITVASSPCFTAQTAWPGIRDDVLHHFQSQLRDDFQRTVERFLALQTLG
TDSARQDARALKSVVLAQPMPSAAVLNGGLSLLRETDLRSQLATLAPLWL
RLYGALDGLVPRRVAPLVDALSPRGRSLIIPGAAHAPFISHPAPFCAALC
DFAGEASA
>eikco-c0dtz8 /F89/ Eikenella corrodens ATCC 23834 Putative uncharacterized protein
MSDSVNIMLLHGWAANHHIFDLLVTNLPECRIAAPDLPGHGAAEFDSAFD
VVAVADSLAAQLNEPAHLLGWSLGGLVALHMAARHPEKVRSLCLTASFAR
LTAAPDYPEGLAKPALGKMIPLFAQDFAKYMRQFLQLQFLHIPERAHLAD
EVLPEIIRHGVPPGLQAALDAVVRTDARALLPQVQCPVLLVFGGKDGITP
PRMGEYLCRQLPNSRLLLIEKAAHIPFLSHADEFSAAYRVFVGLPEKT
>ents8-bioh /F89/ Enterobacter sakazakii (strain ATCC BAA-894) Cronobacter turicensis (strain DSM 18703 / LMG 23827 / z3032) Biotin synthesis protein BioH
MNDIWWQTTGEGNCHLVLLHGWGLNAEVWRCISQELSSHFTLHLVDLPGY
GRSQGYGALTLDEMARLVASRAPECAIWLGWSLGGLVASQVALSEPSRVD
ALVTVASSPCFQAGADWPGIKPEVLSGFQRQLSEDFQRTVERFLALQTLG
TETARQDARVLKSIVLAQPMPGADVLNGGLEILKTADLREALTAWQGPFL
RLYGRLDGLVLRKVAALLDARFPDSESQVFEKAAHAPFISHPREFCDALL
ALKARLANR
>erwae-d4idw0 /F89/ Erwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3; CFBP1430) Biotin synthesis protein BioH
MTGLYWETIGQGDRHLVLLHGWGLNAAVWHCISERLGAHFCLHLVDLPGY
GRSQGFPAMTPDEMVAAILPQAPQRAIWLGWSLGGLVASQLALSHPQRVS
GLISVASSPCFCAQPGWPGIKVETLSGFQQQLSEDFSRTVERFLALQTLG
SDSARQDARMLKSVVLAQPMPTEEVLNGGLEILRTADLRQTMQGLQMPLL
RLYGALDGLVPRNIAALLDASWPTSRSHIIARAAHAPFISHPTEFCAQLM
TFSDTLRP
>erwct-q6czl9 /F89/ Erwinia carotovora (subsp. atroseptica) (Pectobacterium atrosepticum) Pectobacterium carotovorum, Pectobacterium wasabiae, putative biotin biosynthesis protein
MAALYWQTEGAGNTDLVLLHGWGLNAQVWQSMVVRLAPHFRLHLVDLPGY
GRSQGFGPMPLNDMANIVLTQAPERAVWLGWSLGGLVASQIALSAPLRVE
KLITVASSPCFSAQDDWPGIKPDVLQGFQQQLSEDFQRTVERFLALQTLG
TENARQDARLLKGVVLEQPMPSVDVLNGGLEILREADLRQPLADLTVPLL
RLYGALDGLVPRKVAGRLDDEWPNSTSVVMPKAAHAPFISHPDAFTEQVI
AFAQA
>erwpe-d0fx20 /F89/ Erwinia pyrifoliae (strains Ep1/96; DSM 12163 / CIP 106111 / Ep16/96) Biotin synthesis protein BioH
MTGLHWETIGQGDRHLVLLHGWGLNAAVWHCISERLGAHFCLHLVDLPGY
GRSQGYPAMTLDDMVAAILPQAPERAIWLGWSLGGLVASQLALSHPQRVS
GLISVASSPCFSAQPGWPGIKAETLSGFQQQLREDFQRTVERFLALQTLG
SDSARQDARMLKSVVLDQPMPAAEVLNGGLEILRTADLRQAMQELQMPLL
RLYGALDGLVPRSIAALLDVSWPTSRSHIIARAAHAPFISHPEAFSEQVI
AFSDRLLA
>erwt9-b2vjv8 /F89/ Erwinia tasmaniensis (strain DSM 17950 / Et1/99) Biotin synthesis protein BioH
MTALHWETIGQGDRHLVLLHGWGLNAAVWHNISARLGAHFCLHLVDLPGY
GRSQGYPAMTLDDMVAAILPQAPERAIWLGWSLGGLVASQLALSHPQRVS
GLISVASSPCFSAQPEWPGIKTETLSGFQQQLREDFKRTVERFLALQTLG
SDSARQDARMLKSVVLEQPMPTAEVLNGGLEILRTADLRQAMQGLTMPLL
RLYGALDGLVPRKIAPLLDAAWPTSRSHIIARAAHAPFISHPEAFCEQVI
AFSDTLL
>geobb-b5eev9 /F89/ Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622) Biotin biosynthesis carboxylesterase BioH
MPFIETSSGLALHYQETGAGRPVVFLHGWAMSGRVWRFQHPLDDAYRLIF
FDQRGHGQSAAAEGYAIDDYAGDVAALFSRLALEDAVLIGWSLGVQVALQ
AFPSVRERLAGLVLVGGTARFTTAEDYPHGKPPVDVKGLSLKLRRDYQKT
MGDFFKGMFAEGEMDQAQYQRIVMGGRSPNTCAAKESLNILATVDQRDRL
AQVDRPVLLVHGELDTICPAAASAYMAKRMPQARLELVPGCGHAPFMTRP
EGFNALVRNFIEGLRK
>geoka-q5kva3 /F89/ Geobacillus kaustophilus pimeloyl-coa synthesis (biotin biosynthesis)
MNIVCIPGWGMKADIFAPLLDSLSLRGNATVVEWKEIKTVHCFRKRAEQV
LHERATVIGWSLGSLVALELAHAYPERVSRLILIGGTSRFIADDGYEAGW
HPRIVKRMKTKLQVRPADTIAAFLASLWSKSEKGDISEFFYRDRVEELLI
GLDYLIEADARPFLADISAPMLIVHGEQDAICPPAAARYIVERAPSAIQS
HDARIRTALFGARGDHSYLPLPIDPYDPLLRRGFFYGFGRCLADPRKWFG
RTTFPLDSVP
>geols-b3eae1 /F89/ Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) Alpha/beta hydrolase fold
MPFAGPIWYEEHGEGQPILLFVHGWCMSSAVWGLQRDFFAEQYRIIALDL
RGHGQSVVPEKGTTGFGGYAADIVNVVEQLDLRDVVAVGWSLGAQTLLKA
WPDLQGRLVGLVLVGATPRFSAAPHFPYGLPPKEAEGMRLKVRRSLERAL
EGFHRNLFVEHELDDPVVAQQVAEQLGRVVAPQPAAALAGLEALMEEELM
EEAQQVTCPTLLLHGDQDRVCLPAASAWLEQRMHNCRRTLYAGCGHAPFL
SRARQFNHDLLHFVGDLHGTY
>geomg-q39xd9 /F89/ Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) alpha/beta hydrolase fold
MPFVETAQKVTIHYEDEGSGFPLVFVHGWAMSGKVWAFQKPLADHFRLIT
LDLRGHGKSSAAPGYAFSDFAADLAALFDRLGLERAALVGWSLGAQVALE
AVPLLEDRVAALVLVAGTPKFTTADGWPHGLPPHEARGLGLRLKRAYDAT
LGDFFRQMFAEGELSHDQYQRIVREIVIPRHLPDPGAVQACLVTLAGGDH
RNLLPAIAAPTLVIHGDRDAICSPSAGRYLAEGIPGARFLSLEGTGHAPF
LSQPERFNQELSRFLTEVIDRD
>geosf-b9m8u4 /F89/ Geobacter sp. (strain FRC-32) Alpha/beta hydrolase fold protein
MAFFETSDGVTIHYGDLGQGGPLVFVHGWAMSSVVWSFQRELADRRRLIA
MDLRGHGQSAPSENVTLEAFANDLIELFTRLDLHDAVLVGWSMGVQVVLQ
AFNSLRPRLAGLVLAGGTPRFSAAADYPHGLPPVEVKGMGVRLKRDYQKT
MGDFFRGMFAEGEPDREQYQRIVHEIVLKGRSPEPVVARKALQVLADADL
RPLLSRIDRPVLLIHGRNDTICRPEASSYMAEMLPMARLQMVDGGHAPFM
ARSAEFNGLIRAFMEEIIGRH
>geosl-q749w4 /F89/ Geobacter sulfurreducens non-heme peroxidase, putative
MPFLQIDHNLTIHYDDEGDGFPLVLVHGWAMEGGVWAFQRPLASSFRVIT
VDLRGHGRSTAPGDGYGLADFAADIVVLFDELGLERAAIVGWSLGAQAAL
EAAPLLGDRLAALVLVGATPRFSATDGWLHGLPATECRGLGLRLRRTFDA
ALDGFFHSMFAEGELSDESERLIGQEITASWRRPAATAAQAALVTLAESD
QRHLLEKIRVPTLVIHGDRDAICPLEAGAHLADHLPLGRFLLFAGTGHAP
FLSRPREFNSEVTRFLREVAGDD
>geosm-c6e5c9 /F89/ Geobacter sp. (strain M21) Alpha/beta hydrolase fold protein
MPFIETSAGVTLHYQETGAGRPVVFLHGWAMSGRVWRFQHSLDDAYRLIF
FDQRGHGQSATAEGYTIDDYAGDVAALFSQLALEDAVLIGWSLGVQVALQ
AFPSVRERLAGLVLVGGTARFTTADDYPHGKPPVDVKGLSLKLRRDYQKT
MGDFFKGMFAEGEMDQAQYQRIVHEIVMGGRSPDTEAAKESLNILATVDQ
RDLLAQVDRPVLLVHGELDTICPAAASAYMAERMPQARLEVVPGCGHAPF
MTRPEGFNALVRNFIEGLQP
>geour-a5g6i8 /F89/ Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens) Alpha/beta hydrolase fold
MPNFASRDGVTIHYEDVGEGRPLVFIHGWAMSGRVWRFQQELAASRRFIA
MDLRGHGQSTAPMDGYAIDDFADDVVALFTSLDLTDAVLVGWSMGVQVVL
QAFPALRPRLAGLVLVSGTPKFSAAEDYPFGLPPVEVKGMGLRLKRDYQK
TMGDFFRGMFAEEELDREQYQRIVHEILMGGRSPGPEPARQSLKTLADAD
LRPQLGLVDRPVLLIHGARDNICLPAASRFMAERLPLSTLRIIEGSGHAP
FMTKPAEFNRILREFQENICR
>griho-d0i475 /F89/ Grimontia hollisae CIP 101886 Biotin synthesis protein BioH
MDLPGYGRSQPAAAFSLEDMAQCLLDNSPQESVWAGWSLGGMVATQAALL
APERVKGLVTIASSPRFAAEHGWRGIKPEVLQAFTEQLAEDYQTTVERFM
ALQAMGSPTARQDIKWLKQAVLSHPSPQPEALRAGLDILANADLRPQLHE
ISMPWLRIYGRLDGLVPVKVAQELDVLAPRSQRQIFAKASHAPFISDPAH
FTQALLTFCGKCLPSC
>halhl-a1wvm5 /F89/ Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)) Carboxylesterase BioH (Pimeloyl-CoA synthesis)
MTPLLLVPGWSFDGRVFDRLRSVLDTPAQVVELPGHGGAADPRYEDLAGV
ATPVIDAAPDDAVWVGWSLGGTVALEALRRGKPLRGVALIGATPRFTMDI
DWPCAVPAAELTAMRAGLARSPAATVRRFRRRLGQVSAADAAAVTDPCTA
SPVGLAAGLAALAEADLRQAPAGAVPSLWLGGGQDPLVPPAALQRAAEGC
DGQLRILEGAGHLPHCTHATAVAQTIHAFLEEI
>hamd5-bioh /F89/ Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum) Biotin synthesis protein BioH
MKNLYRYSCGEGKLDFVMLHGWGMNSNAWRYIINRFGSHFRLHLFDLPGY
GFSQSEESFTLPEISETVLKKAPPQAIWLGWSMGGCIASEIALRYPERVL
ALITVCSSPCFVSQHQWPRISWQVLSCFEQKLEDHLQNTLEQFLLLQTLG
TLNSQRDTTSLKSFLFSRPLPKKEVLKAGLKILRYTDMRDSLNAISVPFL
RIYGKLDALVPCKIAELLDEAWPHTESVIMHQSAHVPFISHTDDFLEVIL
YFYQKYFSH
>herar-a4g5p0 /F89/ Herminiimonas arsenicoxydans Carboxylesterase BioH (Biotin synthesis protein BioH)
MNPLRLWHGWGMHPAVWSGLCTELAQQDIATQTPALPGYDQSETVAPYNL
DALVDAMLPATNIPYVLCGWSLGALLALHAARRHPQRISRLILIGATPSF
VQRADWPHGIPLAVVDEFIAAVAHDPAAALKRFMALSNQNDVHARSMART
LTQMLTANPLPTAETLIAGLTLLRDSDLRAGIADITQPVLLLHGARDPLM
PVAAAQWLADALPQAQLDILPEAAHTPFLSDQQHCCASIASFYRA
>hyds0-b4u8t4 /F89/ Hydrogenobaculum sp. (strain Y04AAS1) Putative biotin biosynthesis protein
MRVFIHGWGFDNSVFNGISKEEDFKLELPGHGNAINSLEEAAAFYSKLLK
DFKSIEIIGWSMGASLGIMLTQHLKNVTSLKLIGFSPYFKEAHDKITISA
FMRTMKKDFYKGIREFRKNAYHSEFNGEYPIKDIALSILEEYINLDLREA
VKNLDFSIKLIQGENDIVVPMQEAYKTKELNGKIDIFLYKGGHFPTTQVL
KEL
>hydtt-d3dkf1 /F89/ Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) Putative biotin biosynthesis protein
MSELFCIHGWGFSSKVFENLNCHGIDLPAHGKSKLTYKNFESLACDVAMR
ISKPSVLLGWSMGGSLAILIALKFPSKVKGLILIGTTPHFLSSWSEKNVR
AFLIRLRREGEEFLRYFRKLAYPFAFEDSINLSVAYRMLEDYVKLDLTKL
LPYITQRTVIVQGIDDEIVPFISGLTLYNLIKRSKFITFQGGHFPKRYER
FIPEILKGF
>idilo-q5qzc0 /F89/ Idiomarina loihiensis bioh alpha/beta superfamily hydrolase
MSISVTCCGTGTPIVVLHGWGMNSNIWQPVVPALSEHFQLYCVDLPGFGD
SVWSSENDVSLESFIEQIMPALPPRFHLLGWSLGGLIATQIALTHSDRVM
SLTTVASSPHFVESNDWAGIKPDILEQFQQQLDSNFKKTIERFLAIQAMG
SEDAREQVKQVKQLIFTKPMPDQGVLKQSLTILQTADLRQQLPNIEVPFN
RFYGRLDSLVPERAIDDISALAPESKAVVFTKSAHAPFISEPERFISELL
KVVEN
>kankd-c7r785 /F89/ Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125) Biotin synthesis protein BioH
MSKLQPYIESRGQGPDLVLLHGWGLHSGIWEMLADDLAEHFTLHMIDLPG
FGRSPIPGDPYTLNLLTEQVLKVAPENAHYLGWSLGGLIATNIAIESPDR
INKLITVASNPRFVQQDDWQHAMKANIMDSFCRYLEEDYQGTIIRFLAIQ
AIGSETQKDDIRRLRDTVFIHGVPAAKALRGGLALLNDVDLREHLNKIEV
PMLRLYGRLDSLVPAKTAEQVAELIPHSQHKVYPKASHAPFLSHKPLFVN
DVKEFLHE
>klep3-bioh /F89/ Klebsiella pneumoniae, Klebsiella variicola, Biotin synthesis protein BioH
MNDIWWQTIGEGDCHLVLLHGWGLNAQVWDCITPQLASHFTLHLVDLPGY
GRSGGFGAMSLEAMAQRVLEQAPPQAVWLGWSLGGLVASQVAIMRPERVQ
ALVTVASSPCFAARDDWPGIKPEVLAGFQQQLSDDFQRTVERFLALQTMG
TESARQDARALKQAVLSLPMPSAEALNGGLEILRTVDLRQALVRLPMPFL
RLYGRLDGLVPRKIVPLLDDLWPESESILFDKAAHAPFVSHPAAFCEPLL
ALKTRLG
>kursp-BIOHII /F89/ Kurthia sp. 538-KA26 bioh-II
MKQPNLVMLPGWGMEKDAFQPLIKPLSEVFHLSFIEWRDMKTLNDFEERV
IDTIASIDGPVFLLGWSLGSLLSLELVSSYREKIKGFILIGATSRFTTGD
NYSFGWDPRMVERMKKQLQRNKEKTLTSFYEAMFSEAEKEEGFYHQFITT
IQSEFHGDDVFSLLIGLDYLLQKDVRVKLDQIETPILLIHGREDKICPLE
ASSFIKENLGGKAEVHIIEGAGHIPFFTKPQECVQLIKTFIQKEYIHD
>larhh-c1d5s6 /F89/ Laribacter hongkongensis (strain HLHK9) Biotin synthesis protein BioH
MLHIETLGQGPDVVFLHGWSLHGGIWQRVATALADRFTCHLVDLPGHGAS
RTPAVADLAHVADSVADAFPLPVAVVGWSLGGLVAMQWALQRPEAVRALA
LTATSPCFVRQPDWPHAQPAGQIAAVADSLGSDFEATLNRFLALQLLGAP
DARATVNAVRDSLFAHGRPQGLAPMLDVLVAADLRARVSQIACPVWLGFG
ARDAITPLAAGEWLAATLPDALWQPFERASHAPFLSHESEFTARLGDFLA
ARL
>legln-d3ht65 /F89/ Legionella longbeachae serogroup 1 (strain NSW150) D-4968 Biotin biosynthesis protein BioH
MNINIHKYGDGFPLVFFHGWGFDSQVWLALVPKLRPYYQLVLVDLPGFGH
SPIMDWQLFKAVLLNQLPEKFALIGWSMGGLYAMHLALEEPERVDFFISV
TSSPRFLFDDPWPGISQEVFQGFYKNITEDPHRTLSEFLDLHGLAMQAKS
QYLPDKLPSLDGLRFGLSILETWDFRKELKQFTKPAYFMFGRLDPIVSVK
TMRFMQMEYPKFNYMLFKRAAHMPFLSHMDLFIDEIREFIK
>legpa-q5x590 /F89/ Legionella pneumophila (strain Paris) (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 ) (strain Corby) biotin biosynthesis protein bioh
MNIHLDKHGQGMPLVLFHGWGFDNQIWQPIIPYLKPKYQIILVDLPGFGL
TPMMDWESFKKNLLDQLPDKFALAGWSMGGLYATRLAIEEPARVQYLINI
TSSPRFISDIDWPGVAEEVFVNFYNNLSKDINKTLKEFISLQLNKMKFDF
KIGNPPSPEGLAFGLEILGTWDFREQLKQITIPTVYLFGRLDPITPVKTM
AIMEKNYPNFKYVLFNRAAHMPFLSHTDLFITMMDEFIK
>lisda-d0z1b4 /F89/ Photobacterium damselae subsp. damselae CIP 102761 Biotin synthesis protein BioH
MAAELFWHTQGQGPDLVLIHGWGMNSAVWQPVMPLLTSHFTVHCCDLPGY
GESALPSASSLTEIAKQVYLSAPVEQAAWLGWSLGGLVATEIALRAPERV
SHLITVASSPCFAASENWKGIKPAVLQAFMAQLELDFQPTIERFMALQTM
GSPSARQDIKQVKQAVLAKPQPQLAALQIGLQLLAEQDLRPQLGAICQPW
LRLYGRLDGLVPVKTCTEMERLAPQSQAVVFEQASHAPFISHPEQFIDPL
LAFCHP
>magsm-a0l3l8 /F89/ Magnetococcus sp. (strain MC-1) Biotin synthesis protein BioH
MRTVLMVHGWGLAPGLWRPMLGHMGPVELLRADLGFFHPHGQVTVPLPEG
DWLGVGHSMGGLWLLQALLGEAETPQMAALARCKERCRGLVFINGFSRFH
QGADFPHGVGARVIGRMRKQLTVDAMQVLRDFGSRSGLPVMGLPPGVKPH
VARLDEGLAAISRWDGRAILQGWSHPFLAIASREDAIVSAAMSEQMFGGS
ALQWIEGGSHLLPLTHGQQMAAALQQSLESWL
>marms-a6w0x9 /F89/ Marinomonas sp. (strain MWYL1) Carboxylesterase
MRARIETEAFGNSSNQAIFMVSGWAMPKEVMRSFALRLSQRFYVVVANLP
GISLDEQWISRSRIGPNYDIAALSEQLIEVAPKEAWWIGWSLGGMVSAYV
AARRSSRVLGLITLSSSPSFIKREGWEDAMAVEDFDAFVALVEQSPEEGL
KRFVMLQAKGADNERALIKQLQAFLPVKTLSRPALIGGLRLLKSLDVRRE
WSLLDLPNLHLLGGKDALVSSKSLEQQADVNPLQQCVVLSNCAHQSFLED
EETCARHIENFIDANNT
>metca-q609v0 /F89/ Methylococcus capsulatus bioh protein
MGLFIETSGRGPEVVLIHGWGMHGGIWSGFVPWLTDRFRVTRIDLPGHGH
SPMLADWSLETVAGAVLEAVPRPAHWVGWSLGAMVALEAARMAPGAVASL
TLLCGTPRFVAEPGWPGMEAVTLMRFADGFLSDYEDACRRFLALQAWGMP
NERELLRGVRSQLSGRPPPERPALLAGLEVLRHADLRGVLRELPQPVQAL
LGRRDRLVPVELGDALARLKTGLVSHRIDDAPHVPFLTHGERTARLIHEF
IASS
>metfk-q1gza8 /F89/ Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) bioh protein
MSGIHVDIVGKGQPVALIHGWGMHGGVWQPVAKRLAKSFEVHVLDLPGMG
LSQEVIASNLDEMVASLLPALPAHADIVGWSLGGLVAMRLALSQPARVRR
LALVGSTPRFINTEPGHAQPWEYGIAAPVFQKFAQQVGEDYANTLIKFLT
LQCMGARDARATIKELRRSLSDRPAPAPLALESALDVLLQNDLRPELSAL
QQPVLLVHGDRDSLAPVQAAHWLARHLQHASLRVIAGAGHAPFLSHTAQF
IDSVCDFFQPNPGSAR
>metml-c6wu85 /F89/ Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540) Biotin synthesis protein BioH
MIANHLHVETIGAGPNLVLLHGWGMNGAVWQPLVKKLSKLFTLHIVDLPG
MGLSRPIEPFHLSAIAEKVAEVLPAHADIVGWSLGAQVAMRIALDYPDLV
RRLVLVGATPCFVNKSFDQESVEYKSTWDIGIEPEIFGNFADNLNEDYHK
TMTQFLTLQCMGTSDARSTVKLLRNKFSERPAPTSQTLYRALNILLETDL
RAEIEHLRKPTLLVHGDRDSLAPVQAAHWMMKTLPAAYLRVMAGASHAPF
LSHQEQFIDAIVQFLEPQPLKP
>metsd-c6x9j4 /F89/ Methylovorus sp. (strain SIP3-4) (Methylotenera sp. (strain SIP3-4)) BioH protein
MSLHIDIKGTGHPLVLIHGWGMHGGVWQPLIKKLSQHYQLHIVDLPGMGH
SRPLEPAHLHAIAEALAAQLPPHADICGWSMGGLVAMRLALTHPEVVRRM
ILIGSSPRFVNADSDNAASEDGSVDPWSYGIAADVFHQFASQVNADYHAT
LIKFLTLQCMGSSDARATVKQLRSTFSERPVPTAGSLQKALHILLENDLR
HEILHLHKPVLLIHGDRDTLAPVQAAHWLSQHLPFGRLRVIAGAGHAPFL
SHPEQFVHAIDEFLEPGKAGHPLERQP
>neieg-d4drc4 /F89/ Neisseria elongata subsp. glycolytica ATCC 29315 Putative uncharacterized protein
MPPEAEAWHNKQHSGTHKCIHRERIFMNKHLPHSVYLIHGWAANGHVFAD
LCPLLPTNWQVRAPDLPGHGAGQLNGAFDIMAAADTLAAEMPDNSDIVGW
SLGGLVALYIAIRHPHKVRRLCLTSSFAKFLATTDYPQGLNRSALDKMIG
LFEQDYPKYMRQFLQLQLLNTPDGEEIIASVLPDMIKNGTPAALQSALDA
LALADARPFLRQIRQPVLLVYGGKDSITPPRMGEYLEQHLPFAELQIIEK
AAHAPFLSHAAEFSGLLKRFFG
>neig1-bioh /F89/ Neisseria gonorrhoeae, carboxylesterase bioh (EC 3.1.1.1) (biotin synthesis protein bioh)
MRRQQERKFMPDAAKKVYLIHGWGANRHAFDDLMPRLPATWPVSAVDLPG
HGDAPFAQPFDIEAAADGIAAQIDTSADILGWSLGGLVALYLAARHPDKV
RSLCLTASFARLTAAEDYPEGLAAPALGKMVGAFRTDYAKHIKQFLQLQL
LHTPDAAEIIGRILPDLARCGTPQALQEALDAAERADARHLLDKIDVPVL
LVFGGKDAITPLRMGEYLHRHLKGSRLVVMEKAAHAPFLSHAEAFAALCR
DFVEGGLT
>neime-NMA2216 /F89/ Neisseria meningitidis, Neisseria lactamica, Neisseria cinerea, putative hydrolase
MRRQQERKSMPDAVKKVYLIHGWGANRHVFDDLMPRLPATWPVSAVDLPG
HGDAPFAQPFDIEAAADAVAAQIDTPADILGWSLGGLVALYLAARHPDKV
RSLCLTASFARLTADEDYPEGLAAPALGKMVGAFRTDYAKHIKQFLQLQL
LHTPDADGIIGRILPDLARCGTPSALQEALDAAERADARHLLDKIDVPVL
LVFGGKDAITPPRMGEYLHRRLKGSRLVVMEKAAHAPFLSHAEAFAALYR
DFVEGVL
>neimu-d2zuy2 /F89/ Neisseria mucosa ATCC 25996 Neisseria sicca ATCC 29256 Carboxylesterase BioH
MPHSAKKVYLIHGWAANRHVFDDLIPRLPVDWDIRALDLPGHGDAPFAEN
FNIAAIAEAFAEEIDTPAHILGWSLGGLVALHLAARRPDKVRSLCLTASF
ARLTADADYPEGLSNPALGKMVGAFRQDYAKHIKQFLQLQLLHTPNAAEI
IGNIMPDLSRHGAPPALQAALDAVNQADARPLLSSIQAPSLLVFGQKDAI
TPPRIGEYLNRHLTDSELVLMEKAAHAPFLSHADEFAERYRGFVEKVV
>neisu-d3a2p5 /F89/ Neisseria subflava NJ9703 Neisseria flavescens (NRL30031/H210; SK114) Carboxylesterase BioH
MPHSAKKVYLIHGWAANRHVFDDLIPRLPAGWDVRALDLPGHGDAPFAEP
FDIAAVAETFAGQIDTPAHILGWSLGGLVALYLTALYPDKIQSLCLTASF
ARLTADTDYPEGLAQPALGKMVGAFQLDYAKHIKQFLQLQLLHTPHSGEI
LNRVLPDLARCGTPSALQAALEAVNHADARPLLPLIQTPSLLVFGQKDAI
TPPRMGEYLHRHLSDSELVLIDKAAHAPFLSHADEFAEIYRNFVEKAV
>nitec-q0ae74 /F89/ Nitrosomonas eutropha (strain C71) bioh protein
MIWLDADMTRLHIETSGSGPDLVMLHGWAMHSGVWECVSEPLSRRFHLHC
IDLPGHGASRDCALDSLEQMTEVIADHLPDNSIVCGWSLGGQVAIRLALQ
MPERVQQLVLVASTPCFVKRANWPWGMESLTLTLFMENLARDYMQTLNRF
LTLQVSGSEDQTRVLARLRKSMLSGLSPEFATLQAGLKILQTSDLRAELD
QIKQPVLLIHGQNDVIAPVGAAEWTQQHLSQAQLKLFPHCGHAPFLSFPE
QFVGCFDAL
>niteu-BIOH /F89/ Nitrosomonas europaea possible bioh, catalyzes some early step in biotin biosynthesis
MIWPSVDMASIHIETTGNGPDLVMLHGWAMHSGVWDGVVESLSQRFRLHQ
VDLPGHGASRDCALDSLDQMTEVIADRLPGRYSVCGWSLGGQVAIRLALQ
APERVQQLVLVASTPCFVRRADWPWGMEDSTLTLFMENLARDYTQTLNRF
LTLQVSGSEDQARVLAWLRKSILRGQPPTPATLQAGLKILQTSDLRAELN
QVSQPVLLIHGRNDVITPAGAADWMQQHLPRARLVLFPHCGHAPFLSFPE
QFVSCFDAL
>nitmu-q2y9y7 /F89/ Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) bioh protein
MGQVSLYVESLGEGPDLVLLHGWAMHSGMWGSTRRSLAQHFRLHLVDLPG
HGFSRGALPYKRGEKNGVSEDMVERVVEVLPPDCVICGWSLGGQLAIELA
LREPARVEKIILTSTTPSFVKREDWQWGMEELTLKAFAENLRRDFSTTMK
RFLTLQVSGGGDAGKVLPEMRRLLFERSAPEPEALEAGLQIVLANDLRGK
LRNIVQPTLLIHGENDVIAHPEAAAWMKQQFQDVELAMLPNCSHVPFLSY
PDKFIANIVRFAR
>nitoc-q3j9d7 /F89/ Nitrosococcus oceani (strains ATCC 19707 / NCIMB 11848; AFC27) biotin biosynthesis protein, bioh (EC 3.1.1.2)
MTLQIVQRGAGPDLVLLHGWGFHSGVWAPLVDCLSTRFRLTLVDLPGHGG
SDPLAQGRRLAAVAETVARVAPPQACWLGWSLGGLVALQAAIDFPRRVNK
LVLVASTPRFVTAVDWPYGVAPEVLADFSVALQNDSVETLKRFVWLQTRG
AERAKAVAQVLLAHFNAPYRPGIEGLEDGLALLQDSDLRVELETIPCPTL
AIMGQRDPLVPPKVGAWLSAHLPQGQVFMIPRAGHAPFLSHGQVFKDIVS
NFLQA
>oxafo-c3x9p7 /F89/ Oxalobacter formigenes OXCC13 Carboxylesterase bioH
MTTLAFWHGWGISPDVFTPFITELKKDVPDNIHFKAMTLPGYDGMPLPSG
NPCEIWVDAMMKNITGPVILCGWSMGAILAMSAALRYPDRIDRLILFGAT
PCFVEKPDWKNAVSFLTGHQFRTDVENDMHRTLRHFVSLFNHQDKNARNI
VRQLLALPVSPLPVLEAGLDYLAGMDLRSQVADIHQKTLLIHGAFDPLMP
VEAARWLARTLPDATLHILPDVAHAPFLSQPVQCATLVKEFLNQ
>panam-d4gd30 /F89/ Pantoea ananatis (strain LMG 20103) Biotin synthesis protein BioH
MSSLYWHTCGEGDDDLVLLHGWGLNAEVWQNIVPRLSAQFRLHLVDLPGY
GRSRGFAALSLEQMAQTLVPFLPPRAIVLGWSLGGLVATQLALSEPERLR
ALITVASSPCFTARDDWPGIAPLTLHNFQQQLSHDFQRTVERFLALQTMG
TETARTDARKLKEVVLSQPMPDVDVLNGGLTILSDDDLRDRLTAITLPFL
RMYGALDGLVPRRIVQQLDPLLPTSPSVVTDKAAHAPFISHPDAFCQHIV
SFISKLDR
>parl1-a7hvz5 /F89/ Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) Putative uncharacterized protein
MTYSIDHWGDYRNDDDEMTEPGWLSRLGELRIFAELGTLVPALPALLAAP
RGDGHAVLVLPGVLTGDESTFIIRRYLDELGYVTHPWKQGHNWGPSRELH
ERLRARLQELAARYERRISIVGWSLGGIFARELAREFPALVRQVVTLGSP
FGSDYSIDGNRRPDAAARRRIPPPVPCTSIYSRSDGIVSWEACREMDAPE
TENIEVSATHIGMGFNPLVLWAIADRLAQPEGEWSPFDRTGFHSVFYG
>pelcd-q3a3z9 /F89/ Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) non-heme peroxidase, putative
MKFCRLGDGRTISYREQGQGPVVVMLHGWGMSSSVFLPLMQNLSDSFRIL
APDLPGHGHSEPGSGYDLPQLAADMEEWLGIIGITDSYLLGWSLGGMVAL
ELLEHLGGRLKKLILISTSPCFVQRDTWKSGQPATQLKVLGRQFSRDSQA
ALHDFFARQFAGEDLDDHEILNLRHALLDSSPPPTKAAALGGLDTLGRSD
LRRRCWPRVPALVIHGACDAIIPVDAGRYLSRHLPDARWVELEHVGHAPF
VTRTGQCAALFKDFLA
>pelpd-a1aqt0 /F89/ Pelobacter propionicus (strain DSM 2379) alpha/beta hydrolase fold
MPWLRLGSGRRLWYEDQGEGIPLVLLHGWCMSSQVWRFQLETLQRDFRLI
APDLAGHGRSDLSPDGFTLSALCADLDELFRHLDLRSALLAGWSLGAQLA
LQAWGTLRERLSGLVLVSGTPRFIADDDFPHALEARELRGMQARMRRNPL
ITLRDFVSRMFAEAERDVCFPDGRIQRMLASIPLPEGEVALQGLRLLGET
DLRSLLPAVDLPTLIMGGDRDAICLPLASDYMARRIPECRQVVFAGCGHA
PFLTRCTEFNDAITRFSRRIFEQGR
>permh-c0qsh2 /F89/ Persephonella marina (strain DSM 14350 / EX-H1) Putative carboxylesterase BioH (Biotin synthesis protein bioH)
MEIKKIFIHGWSFSSEIWERFKNIGNSVFLDLPFHGNNINFSDKDILNNF
SENLFSYIESCDEEVVLIGWSLGATVGVLTALKKPKNLKKIILIGFSPKF
KDRQLGHDPSRIKAFMMALRKDFEGTVYNFRETAVGNRFTDIPLPEKNGS
IKLLRKFIEIDLTDRLDEIDIPVVLIHGKRDRIINYNASVFCSKKIKNSS
LILTDSHHAPFLEMPEIISDTLI
>phoaa-c7bgr2 /F89/ Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 3105-77) (Xenorhabdus luminescens (strain 2)) Biotin synthesis protein BioH
MADLFWQTSDGDSRDLVLLHGWGLNAEVWRSIEMRCAPHFRLHLVDLPGY
GRSQKYGPMSLADMADEVWRHAPENALWLGWSLGGLVASRIALDHQDKVA
GLITVASSPHFSAEGDWPGIKPEVLSDFEHQLSEDFQRTVERFLALQTMG
TDSARQDARLLKSVVLVQPMPAVEVLHVGLEILCTEDLRESLAALTIPFL
RIYGYLDGLVPRKILNILDEKWPRSVSTIMRHAAHAPFISHPDEFVGLLT
EFVGREAL
>phoas-q1zka4 /F89/ Photobacterium angustum (strain S14 / CCUG 15956) putative bioh protein
MAVMLDWHCKGQGSDLVLIHGWGMNGAVWQDVIPALAEHFTVHWCDLPGY
GYSGDVTAESLVEITQAVLARAPQKAAWLGWSLGGLVATQAALLAPERVT
QLMTLASSPSFMAREEWRGIKPDVLRNFQSQLASDFNLTVDRFLALQAMG
SPTARQDIKNLKQAVLERPTPQPSALALGLTLLETVDQRAELSSLTQPWL
RMYGRLDGLVPVKTEAAITELCPQSLSYVFQSASHAPFISHPDEFIAAVR
QFISEDAVVS
>pholu-BIOH /F89/ Photorhabdus luminescens (subsp. laumondii) biotin biosynthesis protein bioh
MADLFWQTSDEGSRDLVLLHGWGLNAEVWRSIEMRCAPHFRLHLVDLPGY
GRSQKYGPMNLADMADEVWRYAPENALWLGWSLGGLVASRIALDHQDKVA
GLITVASSPHFSAESDWPGIKPEVLHDFEHQLSKDFQRTVERFLALQTLG
TDSARQDARLLKSVVLAQPMPSVEVLHVGLEILRTEDLRQPLAELAIPFL
RIYGYLDGLVPRKIINILDEKWPRSVSAMMRHAAHAPFISHPDEFVGLLT
EFASREVLQGR
>phopr-q6lvq7 /F89/ Photobacterium profundum (Photobacterium sp. (strain SS9 and strain 3TCK))carboxylesterase bioh (EC 3.1.1.1) (biotin synthesis protein bioh)
MTTALCWQTEGQGSDLVLIHGWGMNGAVWQQLLPLLTPFYRVHWVDMPGY
GHSHDISADSIEEMAQLLLDKSPISATWLGWSLGGLVATQAALLAPERVT
RLVTVASSPRFAAEGTWRGIQPQVLDDFRRQLGDDFQLTVERFLALQAMG
SPTARQDIKLLKQAVLSRPQPNPEALSIGLRLLADVDLRAQLGDITQPWL
RLYGRLDGLVPAKVAKDMDQLAPQSCRQIFAAASHAPFISHPEEFVQTLK
DFIK
>promh-bioh /F89/ Proteus mirabilis (strains HI4320; ATCC 29906) Biotin synthesis protein BioH
MNKLYWQTLGEGKTHLVLLHGWGLNAQVWQSIITRLSSHFTLHLVDLPGY
GRSQGFPVLTLKEMADIVFSQAPEKKAIWLGWSLGGLVASRIALDNPNNV
RALITVASSPCFAAHEAWPGIKPDVLKGFEQQLSDNFHRTVERFLALQTL
GTQSAREDTKALKAVVLAQPLPSVETLNGGLEILRTEDLREQLTTLCCPF
IRLYGYLDGLVPRKVAALLDARYPDSPSVIFRHAAHAPFISHPDEFSETL
LKQCEALSILA
>prore-d4c2f8 /F89/ Providencia rettgeri DSM 1131 Biotin synthesis protein BioH
MNEESVTMAKLYWQTVGEGKQDLVLLHGWGLNAQVWQTIIPRIASHFRVH
LVDLPGYGRSQGFSPMNIQSMANILWEQAPKNAIWLGWSLGGLVASRIAL
DHPYEVKGLITVASSPCFKAEENGWAGIRPEVLLGFEQQLSADFHRTVER
FLALQTLGTESARNDAKTLKSVVLEQPIPTVETLNAGLESLRTEDLRDEL
KQLPIPFLRIYGYLDGLVPRKIVPILDELYPNSPSVIMRNSAHAPFISHP
DEFCEYLLDFQSRTEE
>prost-b2puk2 /F89/ Providencia stuartii ATCC 25827 Biotin synthesis protein BioH
MTQLYWETIGEGSQDLVLLHGWGLNAEVWRSIIPRISPHFRLHLVDMPGY
GRSQGFDAMNLAAMADTLWQQAPKEAIWLGWSLGGLIASHIALSHPQQVK
GLITVASSPCFQAHEGSWPGIKSTVLLGFEQQLSTDFQRTVERFLALQTL
GTESARQDAKLLKSVVLEQPMPKVEILNAGLEILRITDLREELKALTVPF
LRLYGYLDGLVPRKVATLLDERYPNSPSVVMRHSAHAPFISHPDEFCEYL
LDFLARLEE
>pse14-q48cs3 /F89/ Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) bioh protein
MRDRLILLPGWGLGVSPLEPLAAALRGLDGHLRVEIEPLPDIDSCDLPDW
LDELDANLPDNAWLGGWSLGGMLAAELAARRGEGCCGLLTLASNACFVTQ
GAWPNAMPAQDFDAFLAGCSADHDATLKRFSLLCTQGAEDSRGLARLLKA
GAPHSSKTALVDGLKILQQLDTRGALQTYRGPQLHLFAGLDAFVPAEAAS
DLLALLPDVEVGLIEQASHAFLVENPHGVAAAIHAFLHELDDD
>psea6-q15n09 /F89/ Pseudoalteromonas atlantica (strain T6c / BAA-1087) bioh protein
MHTTLKTRTVGSGPNFVLLHGWGVNSGVWQPIAKQLEQHFSVTYVDLPGF
GENNQIMPKPYDLKNLAECVANVLPENSVLAGWSLGGLVAQHVALLEPTN
VKQLILIATSPKFQKGNDWAGIDPNILQAFSQQLVKNLSKTIERFLAIQA
MGSDSAKTDIRKIKNSIEASPQADIAALTAGLDILEHVDLRDQIAALKMP
IHWMLGRLDSLVPVKLQGYVQRSLAKNHSVTIFPHASHAPFISHTEDFLI
DLMENTLR
>pseae-PA0502 /F89/ Pseudomonas aeruginosa (and strains UCBPP-PA14; PA7; LESB58; C3719; 2192;) probable biotin biosynthesis protein bioh
MRDHLILLPGWGLGSAPLEPLRDALHEREPHLNVLIEPLPSLDDAADWLD
ELDDNLPRDSWLAGWSLGGMLAGELAARRGDDCRGLLTLASNPCFRVRED
WPNAMPAETFEDFFEAFLLEPHLTRKRFTLLVSQGARDPRTLARQLQVAL
PQLEREALVAGLQLLGQLDTRAALENFRGPQLHLFAEADALVPLAAAEAL
LEWLPDVEVSTLAASHGLPLECPDEVAGAILRFLREGDDA
>psee4-q1i3n8 /F89/ Pseudomonas entomophila (strain L48) biotin biosynthesis bioh
MRNRLILLPGWGLGTASLEPLAASLRAQDSRLQVELMPLPELADSDVQAW
VDHLDRKLPTDVWLGGWSLGGMLASLLAHKRGDHCCGLLTLASNPCFVAR
PDWPHGMAPDTFGTFLDGCRSHTQVTLKRFRTLCSDGALQPRTLLRQLGV
GVPDTDPLYLATGLEVLAKLDTRAALEQYGGPQLHLFAGSDALVPADAAK
ALSDLLPDVEVGLVEDSSHAFLLEYPQELAAGIKSFLHESGDD
>psef5-q4k4t4 /F89/ Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) bioh protein
MRDRLILLPGWGLGVSPLEPLAAALQGLDEHLRVEIEPLPELTSSDPQDW
LDELDDAVPDNAWLGGWSLGGMLASELAARRGERCCGLLTLASNPSFVAH
EQWASAMAGETFDGFLAGCATDPRTTLKRFALLCAQGAADTRGLSRLLLS
GAPTTAPAVLMAGLELLAQLDTREALQGFRGPQLHLFAGLDALVPAEAAG
ELLALLPDIEVGLIEHASHGFLLEDPHGVAGAIQAFLHESGDD
>psefs-c3k362 /F89/ Pseudomonas fluorescens (strain SBW25) Putative biotin biosynthesis-related protein
MRDRLVLLPGWGLGVSPLEPLAAALQGLDEHLQVHIEPLPALGSSDLNEW
LDELDATLPDNAWLGGWSLGGMLASELAARRGERCCGLLTLASNPCFVAH
DAWPSAMPAETFDAFLAGCHADSQVTLKRFGLLCAKGAEDPRGLSRLLVS
GAPNTPSSVLMPGLELLAQLDTREALLAYRGPQLHLFAGLDGLVPAEAAS
DLLALLPDVEIGLIEQAGHAFLLEDPHGVAGAIQAFLHEYVDD
>pseht-q3ijn3 /F89/ Pseudoalteromonas haloplanktis (strain TAC 125) hydrolase domain
MQNELVLLHGWGMNKGVWQLVQPELAFIHNNNVRSIDLPGYGSSKTCPNP
YTLHSAAALLSEQLKPHSILMGWSLGGLFALYIAKHWPEKVAKVILVAAS
PFFAEQAPWPGIKAQVLTQFKEQLVNHGEKTIERFLAIQAMGSESARDDV
KQLKQLLNQYKAPENEALTAGLDILQNEDLRALFTHCPVPISAIFGRLDA
LVPYRAIAQMAALNTEFEYEVLDKASHAPFISHKNEFISAVKSML
>psemy-a4xzr7 /F89/ Pseudomonas mendocina (strain ymp) Carboxylesterase
MRETLILLPGWGLDGAVLQPLAEALGDELQVHVADLPALTSVSVPDWLDE
LDARLPGDCWLAGWSLGGMLAAALAARRGERCRGLIGLASNARFVSSDAW
PQAMPADTYATFYEGCAHNAGATLRRFAMLCAQGSGDARGLARLLQANVL
ANEPSLLAGLQVLATLDNCTALATFAGPQLHLLAEQDALVPAAVADELLA
LLSAGEVDVLEGCGHAFVVEQPQALAGLLLEFIREASDGDA
>psepf-q3k5p3 /F89/ Pseudomonas fluorescens (strain PfO-1) alpha/beta hydrolase fold
MRDRLILLPGWGLGVSPLEPLAAALRGLDEHLQVDIEPLPELDSSDLQDW
LDELDERISEDAWLGGWSLGGMLASELAARRGEHCCGLLTLASNPSFVAH
EQWQSAMPGETFDAFLAGCSADPRTTLKRFSLLCAQGAQDARGLSRLLLG
GAPNTSPAALMAGLELLAQIDTRAALQAFRGPQLHLFGGLDGLVPAEAAG
ELFALLADVEVGLIEQASHAFLLEDPHGVAGAIQAFLSECGDD
>psepu-BIOH /F89/ Pseudomonas putida (strain KT2440) Pseudomonas putida F1 biotin biosynthesis protein bioh
MRNRLVLLPGWGLGTAALEPLAASLRAQDARLQVELMPLPELAHSDVQAW
IDHLDRKLPNDVWLGGWSLGGMLASALAHKRGDHCCGLLTLASNPSFLAR
PDWPHGMAEDTFGTFLDGCRNHTQVTLKRFRTLCSDGALQPRTLLRQLGV
GVPETDPLYLATGLEVLAKLDTREALQAYDGPQLHLFAGSDALVPAEAAK
ALSELLPDVEVGMVEDSSHAFLLEYPQELAAGIKSFLHESGDD
>psepw-b1jec3 /F89/ Pseudomonas putida (strain W619; GB-1; F1 / ATCC 700007) Carboxylesterase
MRNRLILLPGWGLGTAALEPLAASLRAQDSRLQVELAPLPELADADVQAW
VDYLDRKLPSDTWLGGWSLGGMLASELARKRGDHCCGLLTLASNPCFVAR
ADWPHGMADDTFGTFLDGCRSHTSVTLKRFRTLCSDGALQPRTLLRQLGV
GVPDTDPLYLATGLEVLAQLDTREALQAYGGPQLHLFAGSDALVPPEAAK
ALSELLPDVEVGLVEESSHAFLLEYPQELAAGIKSFLHESGDD
>psesy-BIOH /F89/ Pseudomonas syringae (pv. tomato) bioh protein
MRDRLILLPGWGLGVSPLEPLAAALRGLDEHLRVEIEPLPDIDSCEVPDW
LDELDANLPDNAWLGGWSLGGMLAAELAARRGEGCCGLLTLASNACFVTQ
GGWPNAMPAQDFDAFLAGCSVDPDATLKRFSLLCTQGAQDPRGLARLLKA
GAPHSSKTALVDGLKILQQLDTRSALQTYRGPQLHLFAGLDAFVPAEAAG
DLLAVLPDVEVGLIEQASHAFLLENPHAVAAAIQAFLHESGDD
>pseu2-q4zmb0 /F89/ Pseudomonas syringae pv. syringae (strain B728a) bioh protein
MRDRLILLPGWGLGVSPLEPLAAALRGLDEHLRVEIEPLPDIDSCDLPDW
LDELDTNLPDDAWLGGWSLGGMLAAELAARRGDRCCGLLTLASNACFVTQ
GAWPNAMPAQDFEAFLAGCADDPDLTLKRFSLLCTQGAEDPRGLARLLKA
GAPHLSKTALLDGLKILRQLDTRSALQTYRGPQLHLFAGLDAFVPAEAAG
DLLALLPDVEVGLIEQASHAFLLENPHGVAAAIHAFLHELDDD
>pseu5-a4vr86 /F89/ Pseudomonas stutzeri (strain A1501) BioH protein
MRDRLTLLPGWAFGPAALEPLAELLREREPRLQVEIAPLPALEQPGAWLD
ELDARLPSDSWLAGWSLGGMLATQLAARRGDSCPGLITICSNPCFRSRDD
WPTAMQAEVFDAFEEAFRLGPDDTRKRFSLLCSRGAYDPRTLARQLQVSL
LDQPQAVSAAGLRLLAELDGRAALQRYVGPQLHLFAGSDALVPAAAAEAL
LACLPDVEVDVLANASHGLPLERAEDVATAMLAFMGEGEDD
>psyin-a1szh2 /F89/ Psychromonas ingrahamii (strain 37) bioh protein
MIIEQRVYCRVLGEGPNLLLLHGWGVNSAVWDPVLYGLSAHFRVHLIDLP
GFGRSEGLAEYSLDTIVERIMESVPEQSIWCGWSLGGLIASHASYLYPNK
IAKLIQVCTSPKFVGDLLWPGVETIVFENFKLGLLKNSDKTLARFISIQA
MGCESTRKDTLILKKLLKDTKQASLMALSEGLNLLSESDLRREFAQISLP
CLSIFGQFDSLVPIETSVAMQQLLPDSLKKVFMHSSHAPFISEPEEFIDN
IISFSLIKN
>riepu-d4g7k8 /F89/ Riesia pediculicola (strain USDA) Biotin synthesis protein BioH
MQKKLSWKTVGFGKQNIVLIHGFGFNSEVWKNTIHQEDRNFRFHLIDLPG
HGCNHQVLIESVDQVIEKIWENSPKRAIWLGWSLGGLIASEIALRYKDQV
RALITVSSSLYFIQEKKDHLLWPGITEKSLKNFKNQLSENFEETIRRFLF
IQNLGSNLLKKDLKSLKNSILSYPRPNLESLSFWLNVLRKIDLRKVMSKF
KKPFLRIYGEFDQIVPKSVIPLINFLIPNSQSVLIKGSSHAPFISHSEIF
NKIIFYFYRNHR
>rutmc-a1ax96 /F89/ Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica) Carboxylesterase BioH (Pimeloyl-CoA synthesis)
MLYSNTQGFGVDLVLLHGWGFNSELFNTLVDNYKNQYRITIIDLPGHGRS
ANIDGGINEWCNEIIKILPKNSILLGWSLGGLLAIKIASKITLSKLILVA
STPNFIQTDFWEFGIYLNNFEKFSNTLKLNLSKALKRFISLQTKDKLKLK
ELNKAIEQYPVTTQALNQGLEILFNTDLNNQFKKLSIPIEVVLGKYDTLV
PVKISHWYHQNNIKTLILNTGHLPFLHQDFVLPSMLEVKYNPNNT
>sacd2-q21fy5 /F89/ Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Biotin biosynthesis protein BioC
MSNIEPSNVKPSNIELGTIPLAEAPATKLEAAYIAKKIAPNNSNPNAPVW
VFVHGWGASANTWAPLVDELKSQCEIWLLDLPSFGGNTQAVNSPSAVAAD
IAKILPANTVLVGWSLGGMLLPLIAQQIEQHWPTKTISHCIGLAANAKFA
QGDNYTAAMPAETFQTFCANFNVDPTTTWSRFGLLQAQGDSNRKLVSRQI
KALHNAPMPEQFTAWQQALTWLGAIDNRVLLCEITTPFLHLFGEGDALVP
ADAAVAMAGINPLHQTLVVASAGHVLHFSQPAKIAQIMLAR
>salty-BIOH /F89/ Salmonella typhi, S. typhimurium, S. dublin, S. enteritidis, S. gallinarum, S. heidelberg, S. newport, S. paratyphi, S. enterica Putative hydrolase, biotin biosynthesis, reaction prior to pimeloyl coa
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGY
GRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQ
ALVTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLG
TETARQDARTLKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFL
RLYGYLDGLVPRKIVPLLDTLWPHSTSQIMAKAAHAPFISHPAAFCQALM
TLKSSL
>serma-bioH /F89/ Serratia marcescens bioH gene
MTALYWQTIGEGERDLVLLHGWGLNAEVWSCIQALTPHFRLHLVDLPGYG
RSQGFGALSLAQMTEIVLAAAPPQAWWLGWSLGGLVASQAALMQPQRVSG
LITVASSPCFAARDEWPGIRPDVLSGFQHQLSLDFQRTVERFLALQTLGT
ESARQDARQLKAVVLNQPTPSVEVLNGGLEILRTADLRAPLAELNLPLLR
IYGYLDGLVPRKVAELLDAAWPNSTSQIVAKAAHAPFISHPDEFVTMIEA
FIAAH
>serod-d1ryf4 /F89/ Serratia odorifera 4Rx13 Biotin synthesis protein BioH
MTALYWQTIGEGERDLVLLHGWGLNAEVWGCTLERLTPHFRLHLVDLPGY
GRSQGFGGMSLAQMSEIVLAAAPPQAWWLGWSLGGLVAGQIALTQPQRVR
GLITVASSPCFAAQDDWPGIRPEVLSGFQHQLSQDFQRTVERFLALQTLG
TASARQDARLLKSVVLNQPMPSVEVLNGGLEMLRTTDLRLPMAELTLPLL
RIYGYLDGVVPRKVAGLLDVSWPHSSSVVMAKAAHAPFISHPDEFAEIIR
TFVTEGGIPR
>serod-d4dyq0 /F89/ Serratia odorifera DSM 4582 Biotin synthesis protein BioH
MSALYWKTMGEGDRDLVLLHGWGLNAEVWGCTLARLAPHFRLHLLDLPGY
GRSQGYAALTLQQMAEIVLEQAPAKAWWLGWSLGGLVASQIALTQPQRTC
GLISVASSPCFHAEEDWPGIRPNVLSGFQQQLSQDFQRTVERFLTLQTLG
TASARQDARTLKGVVLNQPIPSVEVLNGGLEMLRTVDLRRAMTSLSPALP
LLRIYGYLDGLVPRKVAALVDDLLPASRSVIIDKAAHAPFISHPDEFADV
IKQFVDNSTH
>serp5-bioh /F89/ Serratia proteamaculans (strain 568) Biotin synthesis protein BioH
MTALYWQTIGEGDRDLVLLHGWGLNAEVWSCMLERLTPHFRLHLVDLPGY
GRSQGFAAMSLEQMAEIVLDAAPAQAWWLGWSLGGLVASQIALTQPQRVH
GLITVASSPCFAAQDDWPGIRPEVLSGFQHQLSQDFQRTVERFLALQTLG
TESARQDARLLKSVVLNQPMPSVEILNGGLEILRTADLRQSLAGLSLPLL
RIYGYLDGLVPRKVAGLLDVSWPHSSSIIIAKAAHAPFISQPDEFAEIIG
TFVAENGICRQNAQ
>sheam-a1sbf1 /F89/ Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) bioh protein
MTQGSQAHIHIDTHGTGKNLVILHGWGMNAAVFTPLMGAFPEYRLHCPDL
PGFGHSTMSGDTLDDWVDTLMLALPEQMVLAGWSLGGLVATRAALRYPQR
VEALITIASSPCFMAREEENWPGIPPQVLSQFGAELGKDLPKTIERFLAI
QAMGSETAREDIKRLRDLVLSRPLPQPAALDQGLNMLKDVDLRPELANLS
QPWLRVWGRLDGLVPKRVMPAMPSPAGTCEDLMLAKASHAPFFSHPTEFV
TGVKDWLFRL
>sheb2-b8ecn6 /F89/ Shewanella baltica (strain OS223; OS155/ ATCC BAA-1091; OS195; OS185) Biotin synthesis protein BioH
MSQVTSTNHANLHIEIRGQGPDLVMLHGWGVNSAVFTPLHESLSQYRVHY
VDLPGFGHSQMVEGDLLAWVDALVAALPEHAIWAGWSLGGLVATQAALSY
PQKIKGLITIASSPCFMAREDEAWPGIPPQVLNQFREQLGQNLPKTIERF
LAIQAMGSETAKEDIKRLRDLVLARPLPDARALTQGLSMLTDIDLRPQLT
ELQQPWLRIWGRLDGLVPKRVQPKMPITPQIEDVMLAKASHAPFISHQQE
FLQVFMPWLALQTR
>shedo-q12ic1 /F89/ Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) bioh protein
MNNVNKAKLHVEVQGQGADLVVLHGWGVNNAVFSSLKHELADYRVHYVDL
PGFGHSPSIDGDINAWVEALVSALPSSAIWLGWSLGGLVAKQAAISYPDK
VRALVTVASSPCFMAREIENWPGIAPKVLAQFSSQLGSNLPKTLDRFLAI
QAMGSDTMKQDLTELKQLLLDKPLPQAQALEQGLAMLAQVDLRQELAKIS
QPWLRFWGRLDGLVPQKIQAHLPHGSQIEDVIQHKASHAPFISHQQEFSQ
HLLTWLAKQQ
>shefn-q089g0 /F89/ Shewanella frigidimarina (strain NCIMB 400) bioh protein
MSFPALHIDTVGSQGQDIVLLHGWGVNNQVFSPLKNALHQYRVHYVDLPG
FGLSPNIDGGITQWSQALAEQLPQQAIWIGWSLGGLIASQIAIDYPESVA
ALVTIASSPCFMARESVMTSGIDDISPAWPGIQPDVLAQFSSQLSRDLSR
TVERFLAIQAMGSDNPKADIQQIKSLVLSKPLPTQQGLSQGLDMLAQVDL
RATITQIQRPWLRIWGKLDSLVPRKIISSLPSSDNIEDVLLHKASHAPFI
SHPDAFLDHLLPWITKYR
>shehh-b0tnr7 /F89/ Shewanella halifaxensis (strain HAW-EB4) Biotin synthesis protein BioH
MSQIKLHVESIGQGPDVVMLHGWGVNSAVFTPLHSELNNYRFHYVDLPGF
GHSQAVMGNIEHWLEAIMEQVPEKAIWTGWSLGGLVATLAAIKQPQRVSA
LCTIASSPCFMAREDWPGIPAEVLGQFASQLTQDLDKTVERFLAIQAMGS
QTAKADIKQLRELVLARPSAQQPALAQGLDMLENVDLRSQLSQIDQPWLR
VWGRLDGLVPRRVIKAMPQVSASEDMLLTKASHAPFISHQAEFLDGYKLW
LDKISN
>shelp-a3qj48 /F89/ Shewanella loihica (strain ATCC BAA-1088 / PV-4) Biotin synthesis protein BioH
MSQQSLHIETIGQGRPIVLLHGWGVNSAVFTPLHHTLKDHQLLLVDLPGF
GDSPAIEGDLDAWVDHLMEQLPERAIWAGWSLGGLVATRAALRYPERINA
LLTIASSPCFMARDNEGWPGIPPQILGQFGDQLEKDLGKMIERFLAIQAM
GSETAKQDIKQLRDLVMAKPLPDADALRAGLQMLKEVDLRDQLNEIRVPW
LRVWGRLDGLVSRRVQPLMPVCESRFVDFVLPKASHAPFFSHRDAFVQGV
EAWLQTLKE
>sheon-BIOH /F89/ Shewanella oneidensis Shewanella sp. MR-4 Shewanella sp. MR-7 Shewanella sp. ANA-3 bioh protein
MFTPLHEQLSEYRVHYVDLPGFGLSQPIAGNLSTWIDALINNLPTNAIWA
GWSLGGLVATQAAIDYPSHIKGLITIASSPCFMAREEEAWPGIPPQVLSM
FGEQLGQNLPKTIERFLAIQAMGSETAKEDIKQLRDLVLARPLPDAAALT
QGLDMLNQIDLRMQLSSISQPWLRIWGRLDGLVPKRVQPQMPTASHITDV
MLAKASHAPFVSHRQEFLQALLPWLTQFKD
>shepa-a8h9t6 /F89/ Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) Biotin synthesis protein BioH
MSQSQLHIESIGQGPDVVMLHGWGVNSAVFTPLQGALAKYRVHFVDLPGF
GHSPAVNGDIYDWLNAILEAVPEQAIWTGWSLGGLIATLAAIHHPQRVSA
LCTIASSPCFMAGEDWPGIPEKVLSQFAQQLTQDLDKTIERFLAIQAMGS
ETAKGDIKQLRELVLTKPQAQQTALAQGLAMLERVDLRAELSQINQPWLR
VWGRLDGLVPRRMIKAMPQLPQSQDLLLHKASHAPFISHQQEFLDGFNLW
LDEQV
>shepw-b8cuz1 /F89/ Shewanella piezotolerans (strain WP3 / JCM 13877) Biotin synthesis protein BioH
MSQTKLHVKSVGQGIDVVMLHGWGVNSAVFNALPDMLPEYRFHFVDLPGF
GDSPVINGEIDDWLAAIIDSVPQPAIWIGWSLGGLIASLAAIKYPQYVSR
LCTIASSPCFMAREEESWPGIPSSVLAQFASQLQQDLNKTIERFLAIQAM
GSQTAKGDIKQLREWVLAKPQAQFPALQQGLSMLANVDIREQTTNIKQPW
LRLWGKLDGLVPRKVIQLMPVMENTQDTMLAKASHAPFISHTEEFVTKLE
EWLKSTTYQHT
>shesh-a8fpl6 /F89/ Shewanella sediminis (strain HAW-EB3) Biotin synthesis protein BioH
MNPSPLHIESIGQGQEIIILHGWGVNSAVFTPLHSSLSQYRVHYVDLPGF
GHSSMIEGDIDAWVDAITSRLSHKAIWVGWSLGGLVATRAALRYPERVQG
LVTIASSPCFMAREEESWPGIPPQVLSDFSKQLGSDLSKTIDRFLAIQAM
GSVTAKDDIKQLRELVLSRPLPETTALVQGLDMLKSVDLRPQIAQIEQPW
LRIWGRLDGLIPRRVPPLMPKDEQLYQDLILHRASHAPFISHRDEFITGL
VSWIEKLVRDELLR
>shesw-a1re70 /F89/ Shewanella sp. (strain W3-18-1) Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) bioh protein
MLHGWGVNSTVFTPLYESLSQYRVHYVDLPGFGLSQSVEGDIGAWVDILV
QSLPANAIWAGWSLGGLVATQAALSYPSYIKGLITIASSPCFMAREDKAW
PGIPPHVLSQFSEQLGQNLPRTIERFLAIQAMGSETAKEDIKQLRDLVLS
RPLPDTKALSQGLSMLTKVDLRPQLSALQQPWLRVWGRLDGLVPKRVQPQ
MPTGDQIEDAMLAKASHAPFFSHRDDFLQVFLPWLAIHTR
>shewm-bioh /F89/ Shewanella woodyi (strain ATCC 51908 / MS32) Biotin synthesis protein BioH
MSSSLHIESIGQGQELVILHGWGVNSSVFTPLHASLSEYRVHYVDLPGFG
HSDPIDGDLDDWVDAIINQLPNTAIWIGWSLGGLVATKAALRYPEQVRGL
VTIASSPCFMAREDESWPGIPPQVLSQFSTQLQQNIGKTIERFLAIQVMG
SATAKEDIKQLKELVLSRPLPKNSALAQGLKMLENIDLRAQLPQIEQPWL
RVWGRLDGLVPRRVPPLMPNHQAHFTDLLLPKASHAPFLSHRDEFLTGLT
DWLNKF
>shifl-BIOH /F89/ Shigella flexneri, Shigella sonnei, Shigella boydii, Shigella dysenteriae, Shigella boydii, biotin biosynthesis, reaction prior to pimeloyl coa
MLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAE
AVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDE
WPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVL
ALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVP
MLDKLWPHSESYIFAKAAHAPFISHPVEFCHLLVALKQRVLVVSES
>sodgm-q2nqh6 /F89/ Sodalis glossinidius (strain morsitans) putative biotin biosynthesis protein
MVSLFWQTTGTGDRDLVLLHGWGLNAEVWSYIVPRLATHFRLHLVDLPGY
GRSRGYGALTLEEMAEEVASRAPHGALWLGWSLGGLVATTVARRCPHAVA
GLVTVASSPRFCADGDWPGIRPEVLEGFARELRQDFTRTVSRFLGLQTLG
TASARQDTRWLKSVVLAHPAPAIEVLTGGLALLRTSDVRKALDQLDVPLL
RLYGYLDGLVPRKVVPLVDELSTASHSIVFAGAAHAPFISHPVPFCQALC
DFSQLES
>strm5-bioh /F89/ Stenotrophomonas maltophilia (strain R551-3) (strain K279a) Stenotrophomonas sp. SKA14 Biotin synthesis protein BioH
MHIEVTGRGPDLVLIHGWALQGGVFAPLVQRLADQFTLHLVDLPGHGHSR
DDTTPLRLPFVVNAIAAATPPAVWCGWSLGGLFALHAAATLPKVRGLAMI
AATPRFVRGEDWPHAVEPAVFEQFGRELASDFGGTLERFLALDVMGSAHA
REELRTLRQRLVERGAPTERALLEGLRLLESTDLRGALPTLGKPSLWIAG
QRDRLVSPAAMQAAAALALGGQALTIAHGGHAPFLGHADEVAAALQHFVA
GLSPADGGQ
>sulaa-c1dw76 /F89/ Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825) Putative carboxylesterase BioH (Biotin synthesis protein bioH)
MRKIFIHGWGFSKNIWSNYFYLDDAEFLSLPFHGGSREYTSIESFADYLS
KSINQPTTLIGWSLGASVSVLTALKNKNVKKLILIGFSPKFEDEKLGSPK
ASIKAFMLNLKKDFEKTVRNFRVSAVEKDPLCPVPEKEGSIALLNDFISL
DLREALESVECETHILHGINDKIVNKEAAFFTNQKIKNSQLYLFDSHHAP
FLDRDVLEIVYQ
>sulsy-b2v6x0 /F89/ Sulfurihydrogenibium sp. (strain YO3AOP1) Alpha/beta hydrolase fold protein
MKAVFIHGWGFSKEIFKDYYYLDNSLFLDLPFHGDLQDFEKNNIFEDYVN
YVSNMINEKTTLIGWSLGGSVAFLTALKNPFIEKLVLIGFSPKFNNSLLG
SDPKAIKAFMLNLNNDFENTIYQFRKTATGGEFREIPLPEKEGSKELLKE
YINLDLTEKLHLVDIPTYIIQGDKDSIVNPNSAIYCHEKINNSQLILLDS
NHAPFLERDIFQYIDD
>tertt-c5bmz8 /F89/ Teredinibacter turnerae (strain ATCC 39867 / T7901) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
MTEVNVRAAATPEEKPFLNRTRHEPANPQPNRSVLVFLHGWGSDKRQWQS
FVPTLLEALGDEREMVFIDLPGFGDNSDFRCDDLEHMLKQLARIIPGNAT
LIGWSLGGMIATQLASRHPEKIGRLITIATNPLFVKNDAEIAAGKAPWKH
AMERETFSDFVNGFADDPEATLKRFIALQSMGDSERRQVTDTLKNLLSFS
AHSQQTCWANALSYLDQLDNRTALRNLTQPALHIYGKSDALVPVRAGRAL
QGLAPSHWVESITAAGHAPHISHPREVATMINSFLR
>theah-d3smz6 /F89/ Thermocrinis albus (strain DSM 14484 / JCM 11386 / HI 11/12) Alpha/beta hydrolase fold protein
MSANVFLHGWGFSSKVFRHFEGIKIDLPYHGRSSLRYTSLDKLVEEIALR
VPPHSLLVGWSLGGSVALLLAHRFPKKVKSLILIGTTAHFRRYWPEKNLR
GFLLKVRQKRDSFLWHFRRLAYGREFTDALDIDGATELLEDYMNLNLFPL
LPTIRKPVIILHGVLDQVVPLRAALDLYRRLPKAKFLSFAGGHFPLHEDT
IRKVLKGVSQL
>thicr-q31e53 /F89/ Thiomicrospira crunogena (strain XCL-2) alpha/beta hydrolase fold
MKEITLHTDTLPYLGNLPREQVERLTLIHGWAAENTIWDDWAKETLCPYY
EVTLIELPGFGQSPPFEALAQEEINATWLVALAAQLPEQTHLLGWSLGGL
LAQQLAEQFPEKIKTLTCLASTPRFVQNDGWKWAVSPPLLADFIKAMGVE
YGGVLKQFWRLQLQGSDNARHLMKKLTQHMTNRRLPHYLGLIQGLYLLRD
IDNRDLLLRLKQPTLWLLGEHDPLIPKELIEDLAKLQPDGKTCLVSGASH
MPFFSHPEETAQQLIQFLQAHPYKATP
>thida-q3slx8 /F89/ Thiobacillus denitrificans (strain ATCC 25259) bioh
MSSPKPVLVLVHGWGMNARVFDALADRLDDRFDVRGFDLPGHGGRDAQAV
NTLEAWADALADALPDDANLLGWSLGGQVALRAALDHPRKVARLILVATT
PRFVQRADWASAMDAADLAAFGEALLADPATTLQRFLSLQTRGTPGQKAL
LQHLRQALREAPEPDRVALAAGLAILRDTDLRGDVLRLTHPTLVLHGALD
TLTPAAAGAWLAANLRAARHVELERAAHAPHLSHPDDVAREIERFCL
>thish-b8gpt7 /F89/ Thioalkalivibrio sp. (strain HL-EbGR7) Putative pimeloyl-BioC--CoA transferase BioH
MPPTLLCIHGWGLNGSVWQDLAGALAGRARVLAPDLPGHGARAGEGRFGG
LEAVADELAAGLDARVCVVGWSLGGLLALSLARRHPDKVSSLVLLAATPR
FVRAPDWPHAMDPGVLADFARDLAGDFSSTLARFLALQFLGAPGRGEALR
TLKARCLAMPPAPGGLAEGLEILRGTDLRAELAGLTAPVHGLFGDLDTLV
PVAVVPDLQRLRPDMSVHVLRGAGHAPLLTHVQEVADRLLEWCDGA
>thisk-d3scf3 /F89/ Thioalkalivibrio sp. (strain K90mix) Carboxylesterase
MTRPTLVLLHGWGFSPAVWAPLRAALPGFEIHAPALPGHGELAGGEALGD
PVATCEAIRAQLPRPLSRPIWLGWSLGGLVALELARQMPDTRGLILLNST
PRFAAAPDWGHALPAAELADFQLALEGPRRRLHRRLAMLCARGSPEAASL
AADLTSELEGTPATDQGLAAGLACLMGRDQRACWQSSPVPVAACLAEGDA
LVPSTVADGLRGLRPDARLAVRPGGHAQWWQDPAPVAAFINEFVAALE
>tolat-bioh /F89/ Tolumonas auensis (strain DSM 9187 / TA4) Biotin synthesis protein BioH
MNMYIERIGQGPDLVLLHGWGLNGAVWQEIVPLLQPYYRLHLVDLPGFGY
SRDVIMPDSRLATWSETVLAELPARFDLLGWSMGGLIALRMALDHPSRIN
RLILTGSSPCFLRQDNWPGIHPDVLSGFNCALQQNPRKTIERFLAIQSMG
SESVKEDVKRLKSWLQQRPDAAPAALSAGLALLSSVDLRTELSQLRCPVL
GIYGRQDSLVPAAAVDPIEKLITGSRSVVFAQAAHAPFISHPQQFSEALR
QFLEQNEIQRD
>vesoh-a5cvz2 /F89/ Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) Biotin biosynthesis protein BioH
MLYSNTEGFGVDLVLLHGWGFNSKLFNSLFYNYKNQYRITLIDLPGHGRS
TNIDGGLNEWCDEIIKILPRNPILLGWSLGGLLAINIASKITVSSLILIA
STPNFIQTNNWEFGIDKNNFKQFSNALQLNLSKSLKRFISLQTKNKSKLK
TLNKIIEQYSTTTQALNQGLEILLNTNLNNKFKKLSIPIEVVLGKYDTLV
PIKISHWYHQNNIKTCVLNTGHLPFLHHDFALPSTLEVKYNPSNT
>vibal-q1vap1 /F89/ Vibrio alginolyticus (12G01; 40B) Vibrio sp. (strain Ex25) bioh protein
MGEIESMSTKLHWQSFGQGPDLVLLHGWGMNGAVWQQTVESLQPYFRVHV
VDLPGYGHSAESHAEDLDHIANLVVQGAPEKAIWLGWSLGGLVATHVALN
MPERVAKLITVASSPKFAAEKPWRGIQPNVLSAFTSQLLEDFSLTIERFM
ALQAMGSPSARKDVKQLKQAVLSRPQPNPESLLVGLNILADVDLRDALTS
LSVPMLRLYGRLDGLVPIKVANDLSEQLPHTQQFVFNQSSHAPFITEHDE
FCVQIREFAHD
>vibch-VC2718 /F89/ Vibrio cholerae, Vibrio sp., Vibrio mimicus, bioh protein
MAEWMKMEIDGETVTMALYWQVSGQGQDLVLVHGWGMNGAVWQQTAQALS
DHFRVHVVDLPGYGHSAEQHAASLEEIAQALLEHAPRNAIWVGWSLGGLV
ATHMALHHSDYVSKLVTVASSPKFAAQGSWRGIQPDVLTAFTDQLVADFQ
LTIERFMALQAMGSPSARQDVKVLKQAVLSRPMPNPQSLLAGLTMLAEVD
LRDELQHISVPMLRLYGRLDGLVPAKVARDLNHLAPYSEAFMFDQSSHAP
FMTEAEAFCQQLIEFATR
>vibf1-bioh /F89/ Vibrio fischeri (strain ATCC 700601 / ES114) (strain MJ11) carboxylesterase bioh (EC 3.1.1.1) (biotin synthesis protein bioh)
MTTPLYWQTEGEGSDLVLIHGWGMNGAVWQTTSEKLSQHYRVHTVDLSGY
GHSAELGCADFDEMVKQVLAQAPKKAAWLGWSLGGLIATKAALTSPERVS
QLITVASSPRFSAEKGWRGIKPLVLSQFTEQLKTDFTLTVERFMALQAMG
SPNAKQDIKLVKKAVFSRPMPDQQALATGLMILADIDLREAVSQLSMPVC
RMYGRLDGLVPIKVAHDMDELMPNSAKIVFEQASHAPFISHNDEFISELR
TFLNQHA
>vibfu-c9pjr0 /F89/ Vibrio furnissii CIP 102972 Biotin synthesis protein BioH
MAAALYWQVTGSGPDLVLVHGWGMNGAVWQQTADALAAHFRVHVVDLPGY
GHSAEQHADSLDAIAQRLLEHAPKQAIWVGWSLGGLVATHMALHHREYVA
KLVTVASSPKFAAERPWRGIQPQVLGAFTDQLVDDFQATIERFMALQAMG
SPSARQDVKTLKHAVLSRPSPNPQSLLAGLHMLAEVDLRDQLPHLSMPLL
RLYGRLDGLVPVKVAHDLAHVVPHSQQYIFTESSHAPFMTELEAFCQQLV
AFSREM
>vibhb-bioh /F89/ Vibrio harveyi (strains ATCC BAA-1116 / BB120; HY01; 1DA3) Vibrio sp. AND4 Biotin synthesis protein BioH
MSTNLHWQSFGQGPDLVLLHGWGMNGAVWQQTVESLQPYFRVHVVDLPGY
GHSAESHAEDLAKIADLVLQDAPEKAVWLGWSLGGLVATHIALNAPQRVS
KLITVASSPKFAAERPWRGIQPNVLTAFTDQLLEDFSVTIERFMALQAMG
SPSARKDVKQLKQAVLSRPQPNPDSLLVGLNILADVDLRDALTSLSMPML
RLYGRLDGLVPIKVASDLNEQLPSTQQFVFNQSSHAPFMTEHEAFCLQVR
EFAA
>vibme-c9p1s1 /F89/ Vibrio metschnikovii CIP 69.14 Biotin synthesis protein BioH
MTEKLYWQVIGEGPDLVLIHGWGMNGAVWQQTSQRLQTQFRVHILDLPGY
GYSAQSSAASLAEIAQVVLDQAPSQAIWVGWSLGGLIATHIALHYPQRVT
QLVTVASSPKFTASEQETPVWRGIKPQVLDTFTDQLLTDLPLMIERFIAL
QAMGSPSARQEIKALKQAVLARPMPTHQALLTGLQLLSETDMRQQLTQLT
MPVLRMYGRLDGLVPIRIVEAVQQLQSNSQTSIFQASSHAPFMTEQDAFC
QQLLSFAK
>vibor-c9qdk8 /F89/ Vibrio orientalis CIP 102891 Biotin synthesis protein BioH
MEKVVQGESKLQPLFWHTAGSGDDLVLLHGWGMNGAVWQQTVDVLSQHYC
VHVVDLPGFGHSHQSCFTNMQELASQVLADAPQKAVWLGWSLGGLLATHI
ALNHPERVQKLITVASSPKFAAEKRWRGIKPDVLSNFTEQLVEDFQLTVE
RFMALQAMGSPSARQDVKQLKKAVLSRPAPNPDSLLAGLKLLADIDYRAE
LERLTTPTLRLYGRLDGLVPIKVASDVDNLLPASESHTFSASSHAPFMTE
FDEFCHKVRQFIA
>vibpa-b8k8y0 /F89/ Vibrio parahaemolyticus 16 Biotin synthesis protein BioH
MRKVVQTESTTTPLHWQSSGEGQDLVLLHGWGMNGAVWHQAVEELSQCYR
VHVVDLPGFGHSHQHHFDSIEQMAELVLADAPQQAVWLGWSLGGLLATHI
TAHHPERVTKLITVASSPKFAAERPWRGIQPNVLSAFTEQLVEDFQLTIE
RFMALQAMGSPSARQDVKALKKAVLSRPTPNPKSLLAGLNLLADIDYRDL
LSSIEIPTLRLYGRLDGLVPAKVASDVDKIMPLSESYMFGASSHAPFMTE
LHEFCQQVSRFISEK
>vibpa-VP0148 /F89/ Vibrio parahaemolyticus bioh protein
MGEIESMSTNLHWQSFGQGPDLVLLHGWGMNGAVWQQTVESLQADFCVHV
VDLPGYGFSAEHHGEDLAQIAAMVLKDAPEKAVWLGWSLGGLVATHIALN
APQRVSKLITVASSPKFAAEKPWRGIQPNVLSAFTSQLLEDFSLTIERFM
ALQAMGSPSARKDVKQLKQAVLSRPQPNPESLLVGLNILADVDLRDALIS
LTMPMLRLYGRLDGLVPIKVATDLSQQLPHTQQFVFSQSSHAPFMTEHDE
FCAQVRDFAQD
>vibsl-bioh /F89/ Vibrio splendidus (strains LGP32; 12B01; Mel32)) Vibrionales bacterium SWAT-3 Vibrio sp. MED222 Biotin synthesis protein BioH
MSDTLYWHVSGQGPDLVLVHGWGMNGAVWQQTVDALEADFRVHVVDLPGY
GHSAHCHAQDLEEIAQQLLAEAPKRAIWVGWSLGGLVATHMALHHSDYVS
KLVTVASSPKFAAAKEPVLWRGIQPNVLSAFTEQLVEDFQTTIERFMALQ
AMGSPSARQDVKQLKQAVLSRPLPNPDSLLAGLKMLSDVDLREQLPEISV
PMLRLYGRLDGLVPIKVAKDLGRALPHTEQYIFTQSSHAPFMTEADAFCS
ELVSFAQK
>vibvu-VV10862 /F89/ Vibrio vulnificus (strain CMCP6 and strain YJ016) biotin biosynthesis protein bioh
MSTDLHWQTQGQGPDLVLLHGWGMNGAVWQQVVERLELHFRLHVVDLPGY
GHSAHLHAASLEEIAQQLLEHAPKQAIWVGWSLGGLVATHMALHHADYVS
KLVTVASSPKFAAEARWRGIQPQVLSAFTEQLSEDFHTTVERFMALQAMG
SPSARQDVKNLKQAVFSRPQPNPQSLLAGLQMLAEVDLRDHLPHLTMPML
RLYGRLDGLVPIKVAQDLEKVLPASEQFIFTQSSHAPFITEPESFCHQLL
SFAGK
>wigbr-BIOH /F89/ Wigglesworthia glossinidia brevipalpis bioh protein
MKPFFWRIIGSGSVNLVFIHGWGLNSCIWNNIIIILSNYFKLHLVDLPGY
GKNILYKEYSFSKITEIIACKSPKKSILIGWSLGGLIATNISIVYPEKFK
GLIIVSSSPCFCEKKDWPGIKKEILNNFSFQLKNDFHNTVKKFFNIQFLG
TKKNNNEIKKLKNIFFRQKEPSYKTLSSGLKILKNIDIRNYLKYIKIPTL
RIYGNLDVIVPVKIIPIIKKLQNFNINKNIIIPSASHAPFLSHPFLFCKI
IKYFIKKFN
>xanap-d2uar7 /F89/ Xanthomonas albilineans (strain GPE PC73 / CFBP 7063) Biotin synthesis protein BioH
MHIETLGHGPDLVLLHGWALNGGIFAPLLERLSAQYRMHVVDLPGHGHSR
EDDTPLALPHVVSAIAAATPPAVWLGWSLGGLFALHAAATQPQVRGLAML
AATPRFVRGSDWPHAVAPEVFAQFGHDLTEDYRGTLDRFLALDTLGSAHA
QAELRTLRATLGARSEPDAQVLQDGLTLLERSDLRRALPSLRVPSLWIGG
QRDRLVPPAGMAAAAALAPNAQSLCIKGGGHAPFLGHADDVAEALDGFLS
ALA
>xanax-BIOH /F89/ Xanthomonas axonopodis (pv. citri)Xanthomonas campestris pv. vesicatoria (strain 85-10) biotin biosynthesis protein
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSR
DDSTPLALPYVVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMI
AATPRFVRGSDWPSAVQREVFVQFGVELSRDYRGTLERFLALDTLGSAHA
RSELRSLRETLTARGEPAPEALQQGLTLLERTDLRRTVPQLARPSLWIAG
QRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQVSEALQRFVA
SVP
>xanca-BIOH /F89/ Xanthomonas campestris (pv. campestris) (and strain 8004 strain B100) biotin biosynthesis protein
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSH
DDTTPLALPHVVAAIAAATPAAVWVGWSLGGLFALHAAATQPQVRALAMI
AATPRFVRGSDWPDAVEREVFVQFGQDLARDYRGTLDRFLALDTLGSAHA
RSELRSLRETLTARGEPAASALQDGLGLLERTDLRRALATLARPSLWIAG
QRDRLVPAAGMHAAAARAPHAQALTIDGGGHAPFLGHADQVAEALHRFVA
ALP
>xanor-bioh /F89/ Xanthomonas oryzae pv. oryzae (and strains MAFF 311018; PXO99A) carboxylesterase bioh (EC 3.1.1.1) (biotin synthesis protein bioh)
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSR
DDSTPLALPYVVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMI
AATPRFVRGSDWPDAVQRELFVQFGTELSRDYRGTLERFLALDTLGSAHA
RSELRSLRETLTARGEPAPEALQQGLSLLERTDLRRALPQLARPSLWIAG
QRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQVSEALQRFVA
SVP
>xenbs-d3uyb8 /F89/ Xenorhabdus bovienii (strain SS-2004) Biotin synthesis protein BioH
MNKLFWQIMGEAPRDLVMLHGWGLNSEVWRSVETRLSSHFRLHLVDLPGH
GRSQPYPAMTLAEMADTVWQQAPENALWLGWSLGGLVASRIALDHPAEVA
GLITVASSPKFSAEGDWPGIKPTVLRAFEHQLSEDFQKTVERFLSLQTLG
TDSARQDARLLKSVILNQPMPTVEVLNAGLETLRTDDLRAELAQLQLPFL
RLYGYLDGLVPRKIAAQLDNEWPHTHSVIMRNAAHAPFVSHPDEFVDAVM
EFVANAGL
>xenna-d3vf43 /F89/ Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6) Biotin synthesis protein BioH
MEQLFWQTIGDAPCDLVMLHGWGLNAEVWHSVEKRLASHFRLHLVDLPGY
GRSQSYSAMSLEEMADTVWQQAPENALWLGWSLGGLVASRIALDHPENVA
GLVTVASSPKFSADADWPGIKPEVLSAFEYQLSADFQKTVERFLALQTLG
TESARQDARILKSVILNQPMPSVEVLNAGLEILRTDDLRTELSQLRLPFL
RIYGYLDGLVPRRIMERLDNEWPETHSVIMRHAAHAPFISHPDEFIEVLT
NFTASMRR
>xylfa-XF1356 /F89/ Xylella fastidiosa (and Ann-1) (Dixon) (strain M23)(strain M12) biotin biosynthesis protein
MYIEVTGYGPALVLIHGWAMHSGVFAPLVEQLRAHHTLYLVDLPGHGYNH
TTLTPLALPHVVHAIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLIML
AATPCFVRREDWPHAVEVSIFTQFAEDLKQNYTETINRFLALDTLGSTYA
QSELRQLRQILNARHTPNTATLQAGLELLAHTDLRRAVIDLTPPSLWIAG
QRDRLVPAASIHAATALAPSGQTELLTITGGGHAPFLSHANQMTAALQHF
IATLP
>yeral-c4u8p9 /F89/ Yersinia aldovae ATCC 35236 Biotin synthesis protein BioH
MKQLYWYTCGEGDCDLVLLHGWGLNSEVWRCIIDRLSPHFRLHLVDLPGY
GRSSDFGPMSLADMAGIVLEPAPPQALWLGWSMGGLVASQIALSHPERVH
GLITVSSSPCFAAHDEWPGIRPEVLAGFQQQLSEDFQRTVERFLALQTLG
TESARQDARLLKAVVLTHQMPASDVLNGGLEILRTADLRAQLSNYTQPFM
RIYGHLDGLVPRKVAALLDHAWPHSQSVVMTGAAHAPFVSHPDDFTKLIL
DFSQQNYV
>yerbe-c4rxm4 /F89/ Yersinia bercovieri ATCC 43970 Carboxylesterase bioH
MDLPGYGRSKEFGAMSLPEMAATVLQQAPQQALWLGWSMGGLVASQIALS
HPERVGGLITVSSSPCFTADNEWPGIRPEVLAGFEQQLSEDFQRTVERFL
ALQTLGTESARQDARLLKAVVLQHQMPEVEVLTGGLEILRTTDLREALSA
CSLPFLRIYGYLDGLVPRKVALLLDSAWPRTQSVVMKGAAHAPFVSHPDD
FSNLILEFAQQHQC
>yere8-bioh /F89/ Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) carboxylesterase bioh (EC 3.1.1.1) (biotin synthesis protein bioh)
MKQLYWNICGEGDCDLVLLHGWGLNAGVWHCIIDRLTPHFRLHLVDLPGY
GRSTEFGAMSLSEMAEIVLQQAPQQAIWLGWSMGGLVASQIALSHPERVR
GLITVSSSPCFTAHDEWPGIRPEVLAGFQQQLSEDFQRTVERFLALQTLG
TESARQDARLLKAVVLQHQMPEVAVLTGGLDILRTADLREELADCSLPFL
RIYGYLDGLVPRKVAALLNSQWPHTQSVVMPGSAHAPFVSHPEAFSQLVV
DFAQQSNT
>yerfr-c4sqf6 /F89/ Yersinia frederiksenii ATCC 33641 Carboxylesterase bioH
MSLTDMADIVLQQAPQQALWLGWSMGGLVASQIALSHPERVGGLITVSSS
PCFTANDEWPGIRPEVLVGFEQQLSEDFQRTVERFLALQTLGTESARQDA
RLLKAVVLQHQMPEVDVLTGGLEILRTADLRQELAECAVPFLRIYGYLDG
LVPRKVASLLDRAWPETQSVVMKGAAHAPFVSHPDDFSKLILDFAQQNKA
>yerin-c4t135 /F89/ Yersinia intermedia ATCC 29909 Carboxylesterase bioH
MDLPGYGRSKDFGAMSLPDMAKIVLQQAPEQALWLGWSMGGLVASQIALT
QPERVRGLITVSSSPCFTAHDEWPGIRPEVLAGFQQQLSEDFQRTVERFL
ALQTLGTASARQDARLLKAVVLQHQMPAVEVLIGGLDILRTADLRPALVE
SALPMLRIYGYLDGLVPRKVASLLDSTWPHSQSVVMKGSAHAPFISHPDD
FSKLLIDFLAHVDAKITLK
>yerkr-c4u2a5 /F89/ Yersinia kristensenii ATCC 33638 Biotin synthesis protein BioH
MKQLYWNICGEGDRDLVLLHGWGLNAGVWHCIIDRLAPHFRLHLVDLPGY
GRSNEFGAMSLSEMAETILQQAPKQAIWLGWSMGGLVASQIALQHPDRVR
GLITVASSPCFAAHDEWPGIRPEVLAGFQQQLSEDFQRTVERFLALQTLG
TESARQDARLLKAVVLQHQMPEVSVLTGGLDILRTADLREALAGCSLPFL
RIYGYLDGLVPRNVASLLDHQWPRTQSVVMKGCAHAPFVSHPDEFSKLII
DFAQQNSR
>yermo-c4scr4 /F89/ Yersinia mollaretii ATCC 43969 Biotin synthesis protein BioH
MKQLYWNICGEGDRDLVLLHGWGLNAEVWHCIIERLSPHFRLHLVDLPGY
GRSKDFGAMPLSEMAAIVLQQAPQQALWLGWSMGGLVASQIALRHPERVE
GLITVSSSPCFTAHDEWPGIRPEVLAGFEQQLSEDFQRTVERFLALQTLG
TESARQDARLLKAVVLQHQMPEVEVLTGGLEILRTTDLREALAACSLPFL
RIYGYLDGLVPRKVASLLDHEWPRTQSVVMKGAAHAPFVSHPDDFSNLIL
DFAQQNKR
>yerpe-BIOH /F89/ Yersinia pestis, Yersinia pseudotuberculosis, putative biotin biosynthesis protein
MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGY
GRSQDYGAMSLADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVR
GLITVSSSPCFTARDEWPGIKPEVLAGFQHQLSDDFHRTVERFLALQTLG
TESSRQDARLLKSVVLQHQMPDVEVLTGGLAILRTADLRTALAGFTLPFM
RVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFISHPNDFAKLIL
NFAEENKK
>yerro-c4uun5 /F89/ Yersinia rohdei ATCC 43380 Biotin synthesis protein BioH
MLLHGWGLNAEVWHCIIDRLAPHFRLHLVDLPGYGRSNAFSAMSLSEMAE
IVVQQAPQQALWLGWSMGGLVASQIALSYPERVQGLITVSSSPCFTAHEE
WPGIRPEVLAGFEQQLSEDFQRTVERFLALQTLGTESARQDARLLKAVVL
QHQMPAVEVLTGGLDILRTSDLRSALAQCSLPFLRIYGYLDGLVPRKVAS
LLDREWPGTQSVIMPGAAHAPFVSHPDDFSNLILDFAQQHNR
>yerru-c4uh12 /F89/ Yersinia ruckeri ATCC 29473 Biotin synthesis protein BioH
MTKLYWQTCGEGDRDLVLLHGWGLNAEVWRCMIERLAPHFRLHLVDLPGY
GRSRGYGAMSLHDMAAMVLEQAPRKALWLGWSMGGLVASKIALDHPERVS
GLMTVSSSPCFTAHDEWPGIRPEVLAGFQQQLNEDFQRTVERFLALQTLG
TESARQDARLLKSVVLNHQMPEVDVLTGGLEILRTVDLCRALVDCSVPFL
RIYGYLDGLVPRKVATLLDASLPRSRSVVMKGAAHAPFISHPDDFAELII
NFSCEIALNS