Reference sequence (1): 9eury-c1vei1 Identities normalised by aligned length. Colored by: consensus/70% and property |
1 9eury-c1vei1 100.0% ------------------------------------------------------------------------------------------------------------------------ 2 pelts-a5czq3 38.2% ---------------------------------------------------------------------------------------------------------ALEISP-LQALAGEP 3 bora1-q2l1v4 33.8% -----------------------------------------------------------------------------------------------------MSVLTLTIEP-ADALIDAP 4 ralso-RSC1887 33.2% --------------------------------------------------------------------------------------------------MAASPAFALSVAP-ADDLIDVP 5 borbr-q7wk25 27.0% ------------------------------------------------------------------------------------------------------MPPRMSVAP-ERALIDVD 6 bacld-q65ly2 30.1% ---------------------------------------------------------------------------------------------------MITLQPVLHI-P-AVSKWDEK 7 solus-q43mm3 28.8% ----------------------------------MRI---LIACGI----------------------------------------------------AVCAAAQTIDVTP-PKVMMDEA 8 cloac-CAC3407 25.5% ---------------------------------------------------------------------------------------------------M--KNVKIIIEP-QCSMIDEK 9 clob8-a6lt95 25.6% ----------------------------------------------------------------------------------------------------MENNCTISIMP-ETSKVDEP 10 strmu-SMU.633 21.7% -------------------------------------------------------------------------------------------------------MLTFKLKSQNNHLADSP 11 9flao-q1vpk2 21.0% ML------------------------ETAVRYKLMKIIT-IIKSGLKI----ISATILLIFIPSVLFYSCISSYPSSRVKSQLFNSDTKPCQ-TL--EIKTGKKGTLQVTP-NISYSDDI 12 danre-q5rh34 20.4% --------------------------------------------------------------------------------------------------------------------MDEK 13 danre-q5rhg5 17.9% ----------------------------------MKRWSTLIGRVI-------------MLAP---------------------------VR-TV--STESRRCPMLTVQP-CRGMVDEK 14 danre-q6ph28 17.0% -------------GHLATDNTAPMIIRHSNPSTMMKCWSTLIGRFI-------------MLAP---------------------------IR-TV--STESRRCPLLTVQP-CRGMVDEK 15 danre-q5rhg4 17.5% ----------------------------------MKRWSTLVGRFI-------------MLAP---------------------------VR-TV--STESRRCPLLTVQP-CRGMVDEK 16 danre-q5rh35 18.9% MLKIERRRTGRDHGNIVTD------------SNQFIEERNVYYRTT-------------MLAP---------------------------VR-TV--STANRTSPLLTVQP-RRGLVDEK 17 danre-q5u3w6 20.0% ---------------------------------------------------------------------------------------------------MAEQSPLLTVYP-SSCLVDEK 18 danre-q5spg7 19.5% ----------------------------------MYA------------------TLKCALKP--------------------------FARNTL-AKMHYSSGVSIRLLPSYKCSFEDP 19 danre-q5spg8 20.3% ----------------------------------MFA------------------VLKHAFSP--------------------------LARNTL-AKMHYSSGVSIRLLPSYKCSFEDP 20 danre-q6gmj5 19.3% -------------------------------RDNMYA------------------ALKFAFMP--------------------------FAR-SL-AKVHYSSGVSIKLLPSYKCSFEDP 21 tetng-q4rqz6 22.0% ---------------------------------------------------------------------------------------------------MAGAQVRLKILPSIHSFFNKL 22 human-ACOT1 22.5% ------------------------------------------------------------------------------------------------------MAATLILEPAGRCCWDEP 23 human-ACOT2 19.9% MS-----------NKLLSPHPH----SVVLRSEFKMASSPAVLRASRLYQWSLKSSAQFLGSPQL----------------------RQVGQ-II--RVPARMAATLILEPAGRCCWDEP 24 macfa-q4r4j8 20.7% -----------------------------------MASSPAVLRASRLYPWSLKSWAQLLRSPQM----------------------KQVGR-II--RVPARMAATLILEPAGRCCWDEP 25 mouse-acot1 22.2% ------------------------------------------------------------------------------------------------------MEATLNLEPSGRSCWDEP 26 ratno-acot1 22.0% ------------------------------------------------------------------------------------------------------MEATLSLEPAGRSCWDEP 27 mouse-acot2 20.0% ----------------------------------MVASSFAVLRASRLCQQDWKSWARLFVPPPL----------------------STGGR-T----TWARTNATLSVEPEGRSCWDEP 28 ratno-acot2 20.7% ----------------------------------MVASSFAVLRASRLCQWGWKSWTQLSGPPPL----------------------STGGR-T----TFARTNATLSLEPGSRSCWDEP 29 mouse-acot3 21.9% ----------------------------------MHA---------------------------------------------------------FTTQNPNRMAPTVILEPAGGCLCDQP 30 mouse-acot5 23.4% ------------------------------------------------------------------------------------------------------MVPTVSLEPTGHSCWDEP 31 human-ACOT6 21.3% ------------------------------------------------------------------------------------------------------MAATLILEPAGRCCWDEP 32 mouse-ACOT6 23.1% ------------------------------------------------------------------------------------------------------MAATLSVEPAGRSCWDEP 33 human-ACOT4 22.0% ------------------------------------------------------------------------------------------------------MSATLILEPPGRCCWNEP 34 mouse-acot4 20.2% ------------------------------------------------------------------------------------------------------MAATLSVEPTGRSCWDEP 35 xenla-q6ntq4 23.2% ----------------------------------MLC---------------------LLHRP--------------------------LAR-IL---PACAMSVSMKVSP-GHCLIDEP 36 human-BAAT 20.2% -------------------------------------------------------------------------------------------------------MIQLTATP-VSALVDEP 37 mouse-BAAT 23.1% -------------------------------------------------------------------------------------------------------MAKLTAVP-LSALVDEP 38 ratno-BAAT 23.1% -------------------------------------------------------------------------------------------------------MAKLTAVP-LSALVDEP 39 mouse-acnt1 24.3% ------------------------------------------------------------------------------------------------------MMIKLIATP-SNALVDEP 40 mouse-Q8BGG9 21.4% -------------------------------------------------------------------------------------------------------MIQLIATP-SNALVDEP 41 ratno-q5fvr5 23.0% -------------------------------------------------------------------------------------------------------MLQLIATP-SNALADEP 42 caebr-A8WW80 18.8% ----------------------------------M----------------------------------------------------------------------SIHVDK-PDSMQNEL 43 caeel-W03D8.8 18.1% ----------------------------------M----------------------------------------------------------------------PIHVDK-PDTMQNEL 44 caebr-A8XFE8 16.7% -------------------------------------------------------------------------------------------------------MKHLNIDK-ADSLQPEH 45 caeel-C31H5.6 17.9% ----------------------------------MWLLS----------------------------------------------------K-FF--KKISRKMKHLHIDK-PDTLQPEH 46 caebr-A8XG15 18.5% ---------------------------------------------------------------------------------------------------------MLHVDK-PDSLQAEK 47 caeel-T05E7.1 17.5% ----------------------------------MENQT-----------------------------KCNISYRRIRIDKKKPPKTALKIK-CL--FTFSGFQEMLHVDK-VDSLQTEK 48 caebr-a8xk76 16.9% ------------------------------------------------------------------------------------------------------------------------ 49 caeel-K05B2.4 17.2% ------------------------------------------------------------------------------------------------------MSPVILVTP-EDSLVHEN 50 agrtu-ATU3652 21.5% ------------------------------------------------------------------------------------------------------MIVALIIHR--------- 51 rhil3-q1mg17 23.2% ------------------------------------------------------------------------------------------------------------MPP--------- 52 rhilo-MLR4383 23.7% ----------------------------------------------------------------------------------------------------------MRIGP--------- 53 9sphn-q2n9j1 22.1% ------------------------------------------------------------------------------------------------------------------------ 54 strmu-SMU.1678 20.2% MI----------------------------------------------------------------------------------------------------IAVCLGI----------- 55 trede-q73kp3 17.7% ------------------------------------------------------------------------------------------------------------------------ consensus/100% ........................................................................................................................ consensus/90% ............................................................................................................h........... consensus/80% ..........................................................................................................l.h....ts..tp. consensus/70% .........................................................................................................hl.ltP..pshhs-. 1 9eury-c1vei1 100.0% ---MVSGIAPGTAVTITARTFDRE----------------GRQWASFATFTASSKGVVDIETHAPD-AGTYETVSPMGLIWSMRP---TDG--ESSIYAPP------EGGSDLTLTA--- 2 pelts-a5czq3 38.2% WKIRVSGLTPGAPVTLVAEQQDNK----------------GIKWESHAVFHADQSGVVDPAVQAPV-SGSYEGADPAGLFWSLRP---VAGVKPAGTFAKS------LEPQMITVSV--- 3 bora1-q2l1v4 33.8% RRIVVDGALPGAEVTLATATSRA-----------------GVIWRAAARFVADAQGRVDLGRDAPL-SGSYDGVALMGLIWSQAP---DVAG-RREAFNQPV-----TEALVTEVT---- 4 ralso-RSC1887 33.2% RRIVVTGLVPGAQVDLAARTLRGH----------------AVPWCSRAAFIADADGTVDLSRDAPV-CGDYTGVDPMGLVWSQRP---EGGT-SREVFASAA-----TEPLTTTLT---- 5 borbr-q7wk25 27.0% REIRIDGFGPYACIDVTAEMR-----------------MCGVPWRSRATFLAGADGSLDLGRDSPV-SGDYAEPDAMGLVWSMQC---QDP--PRAVFPPDR-----TDALTVHIT---- 6 bacld-q65ly2 30.1% INLKISGLQPFDTIDIIVTVKDEA----------------DAEWRSHAVFQANRLGEVDPAAAAPL-KGTYQSKDQMGLFWSMQA---VES--SCSFYKKS------VHPSAYRIEV--- 7 solus-q43mm3 28.8% VAVKVSGLAANEHATIRAELTDGG----------------GQQWASQAEYAADENGVIDVLRRAPV-AGSYKELSPMGLVWSMMP---ASK--HVSTYQPPRD----LGPQTIEFTL--- 8 cloac-CAC3407 25.5% TNILVQGLVPYEIITIKALSLDYYRIGAKNNNPDNWKWVKKTNFESFAVFKADDKGTVDLSKDAPI-KGSYTRVDSMGLFWSMVS---TQQ--QDYTLKKSLS----SCPFLTSMEVILK 9 clob8-a6lt95 25.6% VTIKISGLLKNERVLIRALSNDYYCINTSIFDVGN-----KADWESYAVFVADESGTIDLENAKPV-EGTYKEADKMGLFYSMTV---KEN--YKTKIPIRLSDIGENRDYTMTFQV--- 10 strmu-SMU.633 21.7% FELIIERLPPCCQVKVRLDLDHYYNINAPM-NLSS-----QAPWQAEALFYSDDKGILDLSESNP-----YHNLSIMELFFKSQP---IVC--KKAKLSQQLESIPLNPFYDLKISI--- 11 9flao-q1vpk2 21.0% VAIHITGLQPFQIGSLKLSVTDSK----------------DIRWESVACFQANESGEINPENQAPIAGGSYEGKHTMGLFWSLKP---E----KLSSFHFDT-----DLNFTISFD---- 12 danre-q5rh34 20.4% FQVVIKNLLPNQEVTLHSLHQSED----------------KDFWEAFGHYISDEHGTVTVAKDESL-GGTYEGTEQMGLLWSLRPVPGSRP--ALRLRKMNV-----LTPMVINISVYNG 13 danre-q5rhg5 17.9% FQVIIKNLLPNQEVTLHSLHQSED----------------KDFWEAFGHYISDEHGTVTVAKDESL-GGTYEGTEQMGLLWSLRPVPGSRS--ALRLRKMNV-----LTPMVVNISVYNG 14 danre-q6ph28 17.0% FQVVIKNLLPNQEVTLHSLHQSED----------------RDFWEAFGHYISDEHGTVTVAKDESL-GGTYEGTEQMGLLWSLRPVPGSRP--AIRLRKTNL-----LTPMVVNISVYSG 15 danre-q5rhg4 17.5% IQIIIRNLLPNQEVTLHSLHQSED----------------KDFWEAFGHYISDKHGKVTVANDVSL-GGTYEGTEQMGLLWSLRPVPGSRP--ALRLRKKNV-----LTPMVVNISVYSG 16 danre-q5rh35 18.9% FQIVITNLLPNQEVTLHSLHQSED----------------KDFWEAFGHYISDEHGTVTVAKDESL-GGTYEGTEQMGLLWSLRPVPGSRS--ALRLRKTNV-----LTPMVVNISVYNG 17 danre-q5u3w6 20.0% IEVEVKGLPADSKVTVHALVRSDD----------------GDDWEAFGHYTSDPSGTVKVSRDKSV-GGTFEGIEAMGLLWSMRPVPETKP--GRRFRKTNV-----QTPVKVVFSVHEG 18 danre-q5spg7 19.5% VHVTVSGLNPHQRVDLRSKITDEG----------------GRDFKALATYQADDSGQIDLKRDSSL-GGSFTGVEPMGLYWALKA---DTI--SCKFKLKDV-----TRPALVDIEVV-- 19 danre-q5spg8 20.3% VHVTVSGLNPHQRVDLRSKITDEN----------------GLDFKASATYQADDSGQIDLKRDSSL-GGSFTGVEPMGLYWALKA---DTI--SCKFTLSDV-----TRPALVDIEVV-- 20 danre-q6gmj5 19.3% VHVMVSGLNPHQRVNLRSKITDEG----------------GRDFKASAIYLADDNGQIDLKRDSSA-GGSFSGVEPMGLFWALKA---DLL--SCKFKLKDV-----TRPALVDIEVV-- 21 tetng-q4rqz6 22.0% VQVRVEGLAPQKPVELRSRVVDDR----------------GVVFRASALYRADEKGTVDVGSAPAL-SGSYTGVEPMGLFWSLAP---EIL--HSKFTKKNV-----LSPTLVEIEAVNG 22 human-ACOT1 22.5% VRIAVRGLAPEQPVTLRASLRDEK----------------GALFQAHARYRADTLGELDLERAPAL-GGSFAGLEPMGLLWALEP---EKP--LVRLVKRDV-----RTPLAVELEVLDG 23 human-ACOT2 19.9% VRIAVRGLAPEQPVTLRASLRDEK----------------GALFQAHARYRADTLGELDLERAPAL-GGSFAGLEPMGLLWALEP---EKP--LVRLVKRDV-----RTPLAVVLEVLDG 24 macfa-q4r4j8 20.7% VRIAVRGLAPVQPVTLRASLRDEK----------------GALFQAHARYRADAHGELDLEREPAL-GGSFAGLEPMGLLWALEP---EKP--LLRLVKRDV-----RTPLAVELEVLEG 25 mouse-acot1 22.2% LSIAVRGLAPEQPVTLRSVLRDEK----------------GALFRAHARYRADSHGELDLARTPAL-GGSFSGLEPMGLLWAMEP---DRP--FWRLVKRDV-----QTPFVVELEVLDG 26 ratno-acot1 22.0% LSITVRGLVPEQPVTLRAALRDEK----------------GALFRARALYRADAHGELDLARAPAL-GGSFTGLEPMGLIWAMEP---ERP--FWRLVKRDV-----QTPFVVELEVLDG 27 mouse-acot2 20.0% LSIAVRGLAPEQPVTLRSALRDEK----------------GALFRAHARYRADAGGELNLARAPAL-GGSFSGLEPMGLLWAMEP---ERP--LWRLIKRDV-----QTPFLVELEVLDG 28 ratno-acot2 20.7% LSITVRGLAPEQPVTLRAALRDEK----------------GALFRAHARYRADAGGELDLARAPAL-GGSFTGLEPMGLIWAMEP---ERP--LWRLVKRDV-----QKPYVVELEVLDG 29 mouse-acot3 21.9% VHIAVRGLAPEQPVTLRSVLRDEK----------------GALFRAHARYRADSHGELDLARTPAL-GGSFSGLEPMGLLWAMEP---DRP--FWRLIKRDV-----QTPFVVELEVLDG 30 mouse-acot5 23.4% LSIAVRGLAPEQPVTLRTALRDEK----------------GALFRAHARYRADSHGELDLARTPAL-GGSFSGLEPMGLLWAMEP---DRP--FWRLIKRDV-----QTPFVVELEVLDG 31 human-ACOT6 21.3% LRIAVRGLAPEQPVTLRTSLRDEE----------------GALFRAHARYRADARDELDLERAPAL-GGSFAGLQPMGLLWALEP---EKA--LVRLVKRDV-----RTPFAVELEVLDG 32 mouse-ACOT6 23.1% LSIAVRGLAPEQPVTLRSVLRDEK----------------GMLFRAHARYRADSHGELDLARTPAL-GGSFSGLEPMGLLWAMEP---DRP--FWRLIKRDV-----QIPFVVELEVLDG 33 human-ACOT4 22.0% VRIAVRGLAPEQRVTLRASLRDEK----------------GALFRAHARYCADARGELDLERAPAL-GGSFAGLEPMGLLWALEP---EKP--FWRFLKRDV-----QIPFVVELEVLDG 34 mouse-acot4 20.2% LSIAVRGLAPEQPVTLRSVLRDEK----------------GALFRAHARYRADSHGELDLARVPAL-GGSFSGLEPMGLLWAMEP---DRP--FWRLIKRDV-----QTPFLVELEVLDG 35 xenla-q6ntq4 23.2% LRVSVSGLSPGQAVTLQAEMTDEG----------------GEAFTSLSRYHAGSSGELDLSKCPALEGGSFTGVEPEGPLWALQP---KNP--LRRFLRKDV-----ETPIQLKLSLYQD 36 human-BAAT 20.2% VHIRATGLIPFQMVSFQASLEDEN----------------GDMFYSQAHYRANEFGEVDLNHASSL-GGDYMGVHPMGLFWSLKP---EKL--LTRLLKRDVM----NRPFQVQVKLYDL 37 mouse-BAAT 23.1% VHIQVTGLAPFQVVCLQASLKDER----------------KPV-SSQAFYRASEVGEVDLEHDPSL-GGDYMGVHPMGLFWSLKP---EKL--LGRLIKRDVI----NSPYQIHIKACHP 38 ratno-BAAT 23.1% VHIRVTGLTPFQVVCLQASLKDDK----------------GNLFNSQAFYRASEVGEVDLERDSSL-GGDYMGVHPMGLFWSMKP---EKL--LTRLVKRDVM----NRPHKVHIKLCHP 39 mouse-acnt1 24.3% VSIRATGLPPSQIVTIKATVKDEN----------------DNVFQSQAFYKTNEAGEVDLEKTPAL-GGDYVGVHPMGLFFSLKP---KKA--FHRLMKKDVM----NSPFCICLDLYDS 40 mouse-Q8BGG9 21.4% VSIRATGLPPSQIVTIKATVKDEN----------------DNVFQSQAFYKTNEAGEVDLEKTPAL-GGDYVGVHPMGLFFSLKP---KKA--FHRLMKKDVM----NSPLCICLDLYDS 41 ratno-q5fvr5 23.0% VSIRAIGLPPSQIVTITATVKDEK----------------ENLFQSKAFYKANEAGEVDLEQASAL-GGDYVGVHPMGLFCCLKP---KRA--FQRLIKKDVM----NSPLCICLDLYDS 42 caebr-A8WW80 18.8% VEIQALGLTPNQIYTFRMTLKHDY-----------------GTHRSEATFKSDPAGRIDLKCASPL-RGSYHDADPMGLFLGMKP---CEDFAYGGYLRCTP-----PIPFYYHLQLF-- 43 caeel-W03D8.8 18.1% IDIVADGLRSNQIYTFRMILKHDY-----------------GTHKSEATFQADPAGRIDLKYAKPL-RGSYYDADPMGLFLGMKP---CEDFAYGGYLRCTP-----PVPFYYLLELF-- 44 caebr-A8XFE8 16.7% VHITANGLRPGGTYRFDMQLRHNY-----------------GSHASYCVLKADENGNIDMKTAKPL-RGTYFEADGMGLFLSMTP---CEDFAYGGYLRCTP-----PIPFFYLLILS-- 45 caeel-C31H5.6 17.9% VHITASGLQPDRTYRFDMKLRHNY-----------------GSHAAYCVMKADKDGNIDLKEQKPL-RGTYFEADGMGLFLSMTP---SEDFAYGGYLRCTP-----PIPFFYLLQLS-- 46 caebr-A8XG15 18.5% IHITASGLEEWRCYTFILRLHYDR-----------------GTYASFCVIQADSLGNIDFARDAPI-RGMYHDVDPMGLFLSIEP---TQKVRHGHFFKTYD-----PNTFYYTLQLL-- 47 caeel-T05E7.1 17.5% VNIRASGLVEWSCYTFILRLHYDR-----------------GTYASFCVARSDSLGCIDLSRDAPI-RGTYTEVDQMGLFISIEP---TQSIRPGHFFKTYD-----PKTYYYTLQLL-- 48 caebr-a8xk76 16.9% ------------------------------------------------------------------------------------------------------------------------ 49 caeel-K05B2.4 17.2% VSIVVNGLEYQKNYLLELRLLHKV-----------------GIYRSYGVFKSTVTGCIDLSKIAPI-RGTYSGVNESGLFESLEP---TDTVRYGGYCNCTP-----PVDFKYQL----- 50 agrtu-ATU3652 21.5% ----------------------------------------------------------------PL------------------------------------------------------ 51 rhil3-q1mg17 23.2% ------------------------------------------------------------------------------------------------------------------------ 52 rhilo-MLR4383 23.7% ------------------------------------------------------------------------------------------------------------------------ 53 9sphn-q2n9j1 22.1% --MKIRHLT----------------------------------------------AAIALAIVAPIPA----SAEPV------AP----------------------------------- 54 strmu-SMU.1678 20.2% LFVIILGVLF------------------------------IFTMRSFHNFKYSSQGIPN--------TPDYY----------TNPS-------KLSLYKTDI------------------ 55 trede-q73kp3 17.7% -------------------------------------------------------------------------------------------------MKKEIK----------------- consensus/100% ........................................................................................................................ consensus/90% ....h.th...............................................s..t.....s...................s............h...................... consensus/80% hplhhpsL.s.t.hpht..h.pt....................atu.uha.ust.Gplsltpt.sl.tGsa.thp.MGLhhuhps...p.....hthht.s........sh.h.hp.... consensus/70% hplhlpGL.P.p.lslps.hpcp.................ts.apu.uhahusttGplDltpsssl.sGsatshc.MGLhauhpP...pp...hhphhppss......tPhhhplpl... 1 9eury-c1vei1 100.0% ------SADGRQIGQQTVTRWF-GPKKLHTEASPD---------GLLGTLF-RP---SGDGPYPGVMVLHGSGGQPAVGS--ALMLAAHGYAAFAPQYFG--------PPDAVPDQLAEV 2 pelts-a5czq3 38.2% ------EVEGERILAQEVERLYLLPGVKRVEVRES---------GVVGTLF-LP---AGEGRRPAIIVLGGSDGGTYEPA--AAIYASHGYVTLALAYFG---------MEGLPDSLVNI 3 bora1-q2l1v4 33.8% ------AASGETQANARLVQRLAGAGVTRQEVCED---------GLVGTLY-LP---AGPGPHPAVMILNGSGGGINEPR--AALYASHGYAAFALAYFK---------APGLSDYISNT 4 ralso-RSC1887 33.2% ------ATAHGTPACARFVQRLAAPGLTRHDVRDD---------GLVGTLY-LPDPHAHPGPRPAVMVLNGSGGGINEPR--AALYASHGYAAFALAYFK---------APGLSDYISNT 5 borbr-q7wk25 27.0% ------ASDGRHEAHATLVQEFLAEGVRHQAVRAR-----AGGMSLSGELY-TP---PGPGPHPAIIYMNGSSGGVNAPR--AALFAARGYQCLALGVFN---------YEDRPKYLNDM 6 bacld-q65ly2 30.1% ------KQKERIILSKEIKRVLLSETVDRLEVNED---------GLCGTFF-RP---LAVNRPPAIIILGGSDGGLDETM--AGMLANYGYATLAIPYFQ---------YKQLPKKLVEI 7 solus-q43mm3 28.8% ------MRKNEKLAKARLEQTTLAEGVRRRVVREG---------PLRGVIF-AP---PGEGRHPGVLVVGGSNGGLPAKQ--AAWLAAHGFAALALAYFR---------YEDLPQQLEDI 8 cloac-CAC3407 25.5% V-----EVCGKELVSSKCKKLFVSSDVKCQYVTEN---------NLVGKYF-TN---KNSKIKKGIIVLSGSEGGIHNASQIAALLASHGYPSLALAYFG---------MDTLPATLNEI 9 clob8-a6lt95 25.6% ------ERNGRVISSKTHKRIYCDEIISSVDVVED---------KLLGRYF-TS---KENIPKPAIIVLSGSDGRLEKAQAIAEIFAMHGYSALAVCYFG---------LEGTNKSLSCV 10 strmu-SMU.633 21.7% ------FKGHSLLGETSVRRYYQLPSISCLDLNFS---------RAKGRFF-YD---KTSSQQPAIIVLSGSDGRIEKAQNIAQLLASHGFTTLALAYFG---------LEGLASHLEKI 11 9flao-q1vpk2 21.0% ------TGDGDRLTRTILRKSY--ENIENHNITKKE-----IRNKMVANFY-LH---ETDTQRPTLVLLPGSGGNFQHRK--AGYIASKGYNVLDLKYFG---------AKNLPENLENV 12 danre-q5rh34 20.4% HLS-QGFSQASLLATTVTERWYMAPGVKRVNIKEK---------GVLGTLF-LP---PGSGPYPGVLDLWGGGGGLIEYR--SALLASHGFASMALEYLS---------PEKL--KMTEV 13 danre-q5rhg5 17.9% HLS-QGFSQTSALATTVTERWYMAPGVQRVDIREN---------GVRGTLF-LP---PGPGPYPGVLDLWGGGGGLIEYR--SALLASHGFACMALEYIS---------PGEL--KKTDV 14 danre-q6ph28 17.0% HTS-QGFSQTSALATTVTERWYMAPGVQRVDIREN---------GVQGTLF-LP---PGPGPYPGVLDLWGGSAGLIEYR--SALLASHGFACMALEYTT---------PAKL--KKTDV 15 danre-q5rhg4 17.5% HLS-QGFSQTSALARTVTERWYMAPGVQRVDIRES------------------------SGPYPGVLDLWGGGGGLIEYR--SALLASHGFACMALEYLA---------PAML--KLTDV 16 danre-q5rh35 18.9% HLS-QGFSKTSVLATTVTERWYMAPGVQRVNIREN---------GVRGTLF-LP---PGPGPYPGVLDLWGGGGGLVEYR--SALLASHGFASMALEYLS---------PDEL--RTADV 17 danre-q5u3w6 20.0% HLD-KGFKHRTPLSSTAAERWYLTPEVQRVEVTEG---------EIKGTLF-IP---AGSGPFPAVLDLWGGQGGRVEYR--SALLASHGYVSLALEYVG---------LLNAAGELQHA 18 danre-q5spg7 19.5% -------SDDKVLAKVTNERHCLTDGVRRRPLNED---------RIRGTLF-MP---PGKGPFPGILDTYILRGGHFELR--AALLAKRGFAVLALAYQN---------YQDLPKSSDKF 19 danre-q5spg8 20.3% -------SDDKVLAKVTNERHCLTDGVRRSPVTEG---------RIRGTLF-MP---PGKGPFPGILDTNVFRGAPFELR--AALLAKRGFAVLALAFQG---------YQDLPKRADRF 20 danre-q6gmj5 19.3% ------GEDEKVLAKVTNERHCLSEGVRRSLVTEG---------RIRGTLF-MP---TGNGPFPGILDTYILKGGPFELR--AALLAKRGFAVLALAYQN---------YQDLPKKADKF 21 tetng-q4rqz6 22.0% -------ENGEVLASETNERRYMMEGMKRIPVQEG---------RIRGVLF-IP---PGKGPFPGIMDLYTFGGGLSEPR--ASLLANKGYVVLALAYYG---------YQDLPKKPKML 22 human-ACOT1 22.5% HD----PDPGRLLCRVRHERYFLPPGVRREPVRAG---------RVRGTLF-LP---PEPGPFPGIVDMFGTGGGLLEYR--ASLLAGKGFAVMALAYYN---------YEDLPKTMETL 23 human-ACOT2 19.9% HD----PDPGRLLCQTRHERYFLPPGVRREPVRVG---------RVRGTLF-LP---PEPGPFPGIVDMFGTGGGLLEYR--ASLLAGKGFAVMALAYYN---------YEDLPKTMETL 24 macfa-q4r4j8 20.7% HD----PEPGRLLCRARQERDFLPPGVRREPVRAG---------RVRGTLF-LP---PEPGPFPGIVDMFGTGGGLLEYR--ASLLAGKGFAVLALAYYN---------YEDLPKTMDVL 25 mouse-acot1 22.2% HE----PDGGQRLAHAVHERHFLAPGVRRVPVREG---------RVRATLF-LP---PEPGPFPGIIDLFGVGGGLLEYR--ASLLAGKGFAVMALAYYN---------YDDLPKNMETM 26 ratno-acot1 22.0% HE----PDGGRLLARAVHERHFMAPGVRRVPVREG---------RVRATLF-LP---PEPGPFPGIIDLFGVGGGLLEYR--ASLLAGKGFAVMALAYYN---------YDDLPKTMETM 27 mouse-acot2 20.0% HE----PDGGQRLAHAVHERHFLAPGVRRVPVREG---------RVRATLF-LP---PEPGPFPGIIDLFGVGGGLLEYR--ASLLAGKGFAVMALAYYN---------YDDLPKSIETM 28 ratno-acot2 20.7% HE----PDGGQRLAQAVHERHFMAPGVRRVPVRDG---------RVRATLF-LP---PEPGPFPEIIDLFGVGGGLLEYR--ASLLAGKGFAVMALAYYN---------YDDLPKTMETM 29 mouse-acot3 21.9% HE----PDGGQRLARAVHERHFMAPGVRRVPVREG---------RVRATLF-LP---PGTGPFPGIIDLFGIGSGLLEYR--ASLLAGKGFAVMALAYNN---------YEDLPKDMDII 30 mouse-acot5 23.4% HE----PDGGRLLARAVHECHFMAPGVRRVPVREG---------RVRATLF-LP---PGTGPFPGIIDLFGVGGGLLEYR--ASLLAGKGFAVMALAYYK---------YDDLPKVIDIL 31 human-ACOT6 21.3% HD----TEPGRLLCLAQNKRDFLRPGVRREPVRAG---------PVRAALF-LP---PDEGPFPGIIDLFGSSRGLCEYR--ASLLAGHGFAVLALAYFR---------FEDLPEDLNDV 32 mouse-ACOT6 23.1% HE----PDGGQRLARAVHERHFMAPGVRRVPVREG---------RVRATLF-LP---PGKGQFPGIIDLYGSIGGLCEHR--ASLLAGHGFAVLALAYFQ---------FEDLPENLSDV 33 human-ACOT4 22.0% HD----PEPGRLLCQAQHERHFPPPGVRRQSVRAG---------RVRATLF-LP---PGPGPFPGIIDIFGIGGGLLEYR--ASLLAGHGFATLDLQSYN---------FEDLPNNMDNI 34 mouse-acot4 20.2% HE----PDGGRRLARTVHERHFMAPGVRGVPVREG---------RVRATLF-LP---PGQGPFPGIIDVYGVGGGLLEYR--AGLVAGHGFATLALAFYD---------FEDLPKELNVI 35 xenla-q6ntq4 23.2% HE----P-LGQLLATSTQERGFIGAGVSRIPVREG---------KVRGSLF-LP---PGEGPFPGVIEIQGTGGGLLEYK--ASLLAAKGFATLALAYYG---------YEDLPKQMKHF 36 human-BAAT 20.2% ELIVNNKVASAPKASLTLERWYVAPGVTRIKVREG---------RLRGALF-LP---PGEGLFPGVIDLFGGLGGLLEFR--ASLLASRGFASLALAYHN---------YEDLPRKPEVT 37 mouse-BAAT 23.1% YFPLQDLVVSPPLDSLTLERWYVAPGVKRIQVKES---------RIRGALF-LP---PGEGPFPGVIDLFGGAGGLMEFR--ASLLASRGFATLALAYWN---------YDDLPSRLEKV 38 ratno-BAAT 23.1% YFPVEGKVISSSLDSLILERWYMAPGVTRIHVKEG---------RIRGALF-LP---PGEGPFPGVIDLFGGAGGLFEFR--ASLLASHGFATLALAYWG---------YDDLPSRLEKV 39 mouse-acnt1 24.3% VNWLE-TVRIPSKASQRVQRWFVGPGVKREQIQEG---------RVRGALF-LP---PGKGPFPGIIDLFGVIGGLVEFR--ASLLASHGFAVLALAYFA---------YKDLPEKLQEV 40 mouse-Q8BGG9 21.4% VNWLE-TVRIPSKASQRVQRWFVGPGVKREQIQEG---------RVRGALF-LP---P------------------VEFR--ASLLASHGFAVLALAYFA---------YEDLPEKPQEV 41 ratno-q5fvr5 23.0% VCWLE-TVRIPPKASQIVHRWFAGPGVKREQIREG---------RVRGALF-LP---PGKGPFPGIIDLFGSIGGLVEFR--ASLLASRGFAVLALAYFA---------YEDLPKVLLEE 42 caebr-A8WW80 18.8% ------NSVGTLIDETYIKKHWMHPKLERIEMEDD---------GFCATLF-KP---PGDGPFPAVLDLSGTGGGIHEHK--GAMLASEGFVVLCVAFFQ---------YKYLPNKMEEV 43 caeel-W03D8.8 18.1% ------DSSGTLIDSTYIKKHWMHPKLIRTELEED----------FCATLF-KP---PGDGPFPVVLDISGTGGGIHEHK--GAMLASEGFVVLCLAFFQ---------FKYLPQKMEDV 44 caebr-A8XFE8 16.7% ------DESGTKLDEMYIKKHWMHPLLTRTEIEHD---------GFCGTLF-KP---PGDGPFPCVMDISGTGGGLHEHK--GAMLASEGFVVICVAFFQ---------FKDLPYKMEDV 45 caeel-C31H5.6 17.9% ------DDSGTKLDEMYIKKHWMHPLLTRTEIEYD---------GFCGTLF-KP---PGDGPFPCVMDISGTGGGLHEHK--GAMLASEGFVVICVAFFQ---------FKDLPYKLEDV 46 caebr-A8XG15 18.5% ------NDSEEILDEIHLKKHWKHPLVQQINVAES---------GLYGTLF-KP---PGDGPFPTVVFIPGSNGMLESGY--AAVLASEGFATFTFVYYA--------YKKDLPRSIPEV 47 caeel-T05E7.1 17.5% ------DDSKKIIDEIHLKKHWKHPLVEQINVEQN---------GLYGTLF-KP---PGKGPFPAVIFIPGSNGMLESGY--AAVLASEGFLTFTFAYFA--------YKKDLPKLIPDV 48 caebr-a8xk76 16.9% ----------------MFRRRLMYPTVQRIEVEESFPPDAGARPKVTGTIF-KP---PGTGPFPTIIDISGTGGGLNEQK--RAALDSRGFVVLCLAFFK---------YKSLPEDLLTV 49 caeel-K05B2.4 17.2% -------------------LRLMHPLVERIEVEEAYPEGTTGKPKVTGTMF-KP---PGNGPFPTIIDISGTGGGLNEQK--GAALASRGFAVLCLAFFK---------YKDLPYELQEV 50 agrtu-ATU3652 21.5% -------TKRQKMVAYDVEQ------------LEG---------KVRGALL-QGT----NSGKTGVIVLGGSSGRVDTTR--AGLFANTGARALALQWFG---------GANQPPGICEI 51 rhil3-q1mg17 23.2% -------GRRSLVLDAGYQR------------LPP---------PLQGEIF-RVK----PDTGTGVVVLGGSSGRVDVAR--ARLFASQGATVIALRWFG---------GDGQVPGICEV 52 rhilo-MLR4383 23.7% -------S-RPHLAEARTGRMD-EPAVTE-EILSG---------GVAGTLL------QCADAMTGVVVLSGSSGRVDAAR--AKLFASEGVSALALQWFG---------GEGQVPGICEI 53 9sphn-q2n9j1 22.1% ---------------------------TEIIVGQD----------MPGAFFAVP---EGTGPFPAIILLGGSEGGDSTARRMAPRFLAQGYAIFGLPYYSPAWGDREQQFPALSDAFDGI 54 strmu-SMU.1678 20.2% ------------------------AGLTIEHVTGD---------YLNGFRI-IP---DNIKYKGVIVTFGGSDGTPAYEQ--AVQLAQEGYQVLALFFFG---------MPNQHPTLAEV 55 trede-q73kp3 17.7% ------------------------------TIEKD---------GYNGVYW--P---NPNGSKYCMIAMLGDDTKDMMAKGGVKWLQKKGLNVLTMSPAP---KDY---------GHHNY consensus/100% .....................................................................................h...Gh..hs......................... consensus/90% ...................p......hpp..ltts..........h.utha.hs....t.s.hsslh.h.G.tGt..t.p..uthhAtcGasshsltaht...........th...h..h consensus/80% .........tt.hsp.hhp+hhh.stlpc..lpps.........tlhuslF.hP...st.GshPullsl.GssGsl.ph+..uuhLAucGasshuLtaat.........hpsLs.phpph consensus/70% .......tttphlsphhhc+hahtssVpR..lpcs.........tlpGsLF.hP...ss.GPaPullsl.GssGGl.Eh+..AulLAu+GasshALsYas.........hcsLPpphppl 1 9eury-c1vei1 100.0% PLEYLQRGYDWLTSRPAVRDGSVGLLGTSKGAELALLAGATFD-WVG--AVAAYAPSGIVWAGLTYG---------GEMTSSWTLDGDP--VPFVPT-AFPPSV---IADYV-ASW---- 2 pelts-a5czq3 38.2% PLETVGKAIEWLESRPEVDKDAIGVWGASKGAELALLAASHYP-QIK--AVVAKSPSAVVFEGISKD-------SGKNHQSSWTYKGEP--LSFVPT-IFTEEL---AGSYF-AAV---- 3 bora1-q2l1v4 33.8% PLEYFQRGLRWLRRRVRPAHDFVALSGQSRGGELVLLLGATFPEEVS--AVVAYVPGAVVHSGQNAA-D----PKIGREGPTWLLDGKP--LTHVW-----------ENNRS-ASWKP-- 4 ralso-RSC1887 33.2% PLEYFERGLAWLRRRVRPLHDFVAVSGQSRGGELALLLGATFPAAVS--AVIGYVPGAVVHSAQNAA-D----PAIGREGPTWLYRGRP--LPHLW-----------EGNRT-ATWAP-- 5 borbr-q7wk25 27.0% PLEYLEQALRWVRDTLNPRDGFVAISGISRGGEMSLLAASHFPELVS--AVVAYVPSPVMHGVVSAG-A----PGTGRDAQVWTLGGKP--LPHLW-----------QDNAT-ADWEA-- 6 bacld-q65ly2 30.1% PLEYFQKAIDWLGRQEGLHHRQIGICGRSKGGELALLIGSHFP-EIR--FVVSHVGGGVVFQGVGLK--------KFRQTSSWSLNGAP--LAFAPLPMFSLPQ---LWNMM-KHK---- 7 solus-q43mm3 28.8% PLEYFGRALEWMAQQKEIAPDHLAVMGTSRGGELALQLGSMFP-SIR--AVVAYVPADVRYASCCLM----------KGTAAWTWQGQA--LPYLAP-RFGR------------------ 8 cloac-CAC3407 25.5% PLEYFEKAIDWIITKGDISPNNLTVFGRSRGGELALLLGSTFK-KIT--SVIAVAASPILFGT------------NTTKLSSWKYKGED--IPYLN-----------LKINI-ISFLKNA 9 clob8-a6lt95 25.6% ELECVENAIDWLKKQSTVAKNKIGIYGRSKGGEMVLLAASIFK-DIS--CVIANTPSCYVYEGLKAN-------KFPSKHSSWMYKGRE--IPYIKF-SFSI-----LIRTL-VKM---- 10 strmu-SMU.633 21.7% PLEIIQEAIDYLKKSPYADSIRLGLYGRSKGAEFALLAASHYA-DFK--CLVLNSPSYLCLEGLKQW--------RNSKTSSWTYQGQE--LPYHPF-LWKDFF---------------- 11 9flao-q1vpk2 21.0% PLEYLHNAINWLKNKPAVDSSKIALMGRSKGAEYALLYASKYN-DVK--ALVSEVGSSVTWSS------------KRYIKSPWSYNGKG--VPKAR-----------GGIRY-LKS---- 12 danre-q5rh34 20.4% DGTYFEKAYQILQNHPLVQKDKMAVLGLCFGSAITLTMTAYSR-VIKPQCCVCISGSHA--------------------------------IPVDKC-LFEVFEDIKKLNGK-IQV---- 13 danre-q5rhg5 17.9% DNTYFEKAYQILQNHPLVQKDKMAMLGLCFGSVITFSMTVYSS-VIKPQCCVCISGSHV--------------------------------VPVNKC-MFEVFEDIKKLMGK-VQE---- 14 danre-q6ph28 17.0% NNTYFEKAYKILQNHPLVQKDKMAMLGLCFGSAITFSMTAYSS-VIKPQCCVCISGSHV--------------------------------VPVDKC-IFEVLEDMKRRMGK-VPV---- 15 danre-q5rhg4 17.5% NNTYFEKAYQILQNHPLVQKDKMAMLGLSFGSAITFSMTAYSR-VIKPQCCVCISGSHV--------------------------------VPVDKC-LFKVIEDFTGLVDK-VPV---- 16 danre-q5rh35 18.9% DVSYFENAYQILQNHPKVQKNKMAMLGLSFGSAITFSMAAYST-IIKPQCCVCISGSHV--------------------------------VPVDKS-LFEVFEEIKKNMDK-VHV---- 17 danre-q5u3w6 20.0% DNSYFEAAFTFLQKHPRVCPDKVAVMGMSFGVSVTLGLTAYSE-IVEPKCVVCVSGSHI--------------------------------MPLKGS-LADVYAALQQNVHK-IRY---- 18 danre-q5spg7 19.5% HLEYFEEGIDFLRQQPEVKGQKIGLLSISKSGDLALSMSTFLP-DIA--ATVWINGCNA------------------NSVVPLYYKDMY--IPPLT-----------LDFKK-KKI---- 19 danre-q5spg8 20.3% HLEYFEEGIDFLRQQPEVKGQKIGLVSISKSGDLALSMATFLP-DIA--ATIWVNGCNA------------------NTLVPVYYKDIC--VPPLL-----------FDVKR-TKI---- 20 danre-q6gmj5 19.3% HLEYFEEGLDFLRRQPEVKGQKIGLLSISKSGDLALSMSTFLP-DIT--AAVWINGCNA------------------NSLIPLYYKDMY--IPPLT-----------LDFKK-KKM---- 21 tetng-q4rqz6 22.0% DLEYFEEAATYLSVHPEVRGPGIGLISISHSGGLALAMSSFLS-GIT--ATVCVNGCIG------------------NTVLPLRYKDMV--IPPLP-----------PVAEN-ITL---- 22 human-ACOT1 22.5% HLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLK-GIT--AAVVINGSVA------------------NVGGTLRYKGET--LPPVG-----------VNRNR-IKV---- 23 human-ACOT2 19.9% HLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLK-GIT--AAVVINGSVA------------------NVGGTLRYKGET--LPPVG-----------VNRNR-IKV---- 24 macfa-q4r4j8 20.7% HLEYFEEAVNYLLSHPEVKGPGVGLLGVSKGGELCLSMASFLK-GIT--AAVIINGSVA------------------NVGGTLHYKGET--LPPVG-----------VNRNR-IKV---- 25 mouse-acot1 22.2% HMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLK-GIT--AAVVINGSVA------------------AVGNTISYKDET--IPPVT-----------ILRNQ-VKM---- 26 ratno-acot1 22.0% RIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLK-GIT--AAVVINGSVA------------------AVGNTICYKDET--IPPVT-----------ILRNQ-VKM---- 27 mouse-acot2 20.0% HMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLK-GIT--AAVVINGSVA------------------AVGNTISYKDET--IPPVS-----------LVRNQ-VKM---- 28 ratno-acot2 20.7% RIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLK-GIT--AAVVINGSVA------------------AVGNTVCYKDET--IPPVS-----------LLRDK-VKM---- 29 mouse-acot3 21.9% HLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLK-NIT--AAVIINGSIS------------------NIGGNLQYKDET--VPSVG-----------INTKR-VKR---- 30 mouse-acot5 23.4% HLEYFEEAVTYLLSHPQVKGPGVGLLGISKGAELSLSMASFLK-GIT--AAVVINGATV------------------NVISTLYYKEES--LPGLG-----------MHLER-IKV---- 31 human-ACOT6 21.3% HLEYFEEAVDFMLQHPKVKGPSIALLGFSKGGDLCLSMASFLK-GIT--ATVLINACVA------------------NTVAPLHYKDMI--IPKLV-----------DDLGK-VKI---- 32 mouse-ACOT6 23.1% RLEYFEEALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNIT--ATVLINACVA------------------NTLVPLYYKDLF--VPELG-----------CDQTK-------- 33 human-ACOT4 22.0% SLEYFEEAVCYMLQHPQVKGPGIGLLGISLGADICLSMASFLK-NVS--ATVSINGSGI------------------SGNTAINYKHSS--IPPLG-----------YDLRR-IKV---- 34 mouse-acot4 20.2% EVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLN-NVS--ATVSINGSAF------------------SGNRHIKYKQTM--IPPLG-----------HDLRR-MKV---- 35 xenla-q6ntq4 23.2% HLEYFEEAVNFMLKHPKVKGPGIGLLGHSKGGDLVLSMTAFLK-GIP--AAAVVNGSLA------------------NVGADLHYRDIT--LPAIG-----------FDINK-IKF---- 36 human-BAAT 20.2% DLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLK-QVT--ATVLINGTNF------------------PFGIPQVYHGQI--HQPLP-----------HSAQL-IST---- 37 mouse-BAAT 23.1% DLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLK-QIR--ATVLINGPNF------------------VSQSPHVYHGQV--YPPVP-----------SNEEF-VVT---- 38 ratno-BAAT 23.1% DLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLK-QIT--ATVLINGPNF------------------VSSNPHVYRGKV--FQPTP-----------CSEEF-VTT---- 39 mouse-acnt1 24.3% DLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLK-QVI--ATVCINGATT------------------TTAVPLRYQDLV--VTPIQ-----------QALER-MEV---- 40 mouse-Q8BGG9 21.4% DLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLK-QVI--ATVCINGPTT------------------ITIFPLRYQDLV--MTPIH-----------PALER-IQV---- 41 ratno-q5fvr5 23.0% DLDYFEEAANFLLAHPKIQQPGIGVISVSKGAEIGLAMACYLK-QVV--ATVCINGPSA------------------IFDFPLKYRDLV--VTPMR-----------LAFEK-IQF---- 42 caebr-A8WW80 18.8% NMEYFSKPIEYLANLPY-TLNVIGIQGVSFGATIVDLLATRHGDKIK--AVVSINGPQVV-----------------SDYLYMQENGEP--IPHLS-----------HGQVT-LEH---- 43 caeel-W03D8.8 18.1% DMEYFAKAINYLIDLPF-TKNVIGIQGVSFGATIVDLLTTRHGDKIK--ALVSINGPQVV-----------------SDYLFMQENGAP--IPHLS-----------HGQVT-LEH---- 44 caebr-A8XFE8 16.7% DVEYFLKPIEFVLGLPY-TTNMLGIQGVSFGATIVDLLSTRYP-QIK--AVVSINGPHAQ-----------------SHYCLLKEHGKPMDVPYLD-----------DSKLF-------- 45 caeel-C31H5.6 17.9% DVEYFLKPIEFVLGLSY-TTNMLGIQGVSFGATIVDLLSTRYP-QIK--AVVSINGPHAQ-----------------CSYSLLKEHGKQMIVPELD-----------DSKLY-------- 46 caebr-A8XG15 18.5% DIEFFAKPIEYVQSLPY-CSKKIGLVGQSFGGLTANFLSTKYH-QVS--AVVALNCSAAYC----------------RDIAVMRENGKPMEVQLLD-----------EGMSD-------- 47 caeel-T05E7.1 17.5% DIEFFEKPIEYVQNSPY-CSGKIGLVGQSFGGLTANYLSTKYH-QVS--AVVALNCSAAFC----------------RDNAVMKENGKPMETQILD-----------EGMSD-------- 48 caebr-a8xk76 16.9% ELQYFEDAINYITSLPY-TRDRIVFQGVSFGGTLVMFLTTKFP-KIK--AVCSINGSFAM-----------------DQFAHVRVNGK---CPPIG--IFKA-----DGAH--------- 49 caeel-K05B2.4 17.2% ELRYFEDAINFVTSLPY-TNDRIGFQGISFGGTLVMFLTTRFK-Q------------------------------------HFR---------------FIN-----QGIED-------- 50 agrtu-ATU3652 21.5% PLETFVDATDLLISR---GCDRTVFVGTSKGAEAALLASTIDH-RIN--VVIAISPSSVVLGNIGAG-VD---GISWPERSSWSFKRSP--LDFVP-----------ADINW-QKD---- 51 rhil3-q1mg17 23.2% PLETFFAATDYLIEL---GCKRIVLVGTSKGAEAALLTAVYDP-RIS--AVVAMSPSSVVWGNIGPG-LD---GISWPERSSWTLRGTP--LPFVS-----------SGPEW-VRE---- 52 rhilo-MLR4383 23.7% PLEIFFAATDHLVGL---GCRRIVYVGTSKGAEAALLAAAHDQ-RID--AVIAISPTSVVWGNIGPG-RD---GISWPERSSWTLKGVP--LPFVP-----------TRPNW-RAS---- 53 9sphn-q2n9j1 22.1% AIEKAEMARAWLAERDEVRADDIGIWGVSKGGEFALLAGSYLD-GFA--AIAAIVPSDVVWEGWGP-------GRESGTVSSFSWQGEP--LPFVP---YEG-----MAEEF-ANPT--- 54 strmu-SMU.1678 20.2% PVEYYQEIESYISQHFS-QPDKITVIGTSKGAEYALLLASLYD-SID--NVVLYAPSSHIYAGLDFR----------NYSSSWSQNGKA--LPYLD-----------VRSENSLKLFY-- 55 trede-q73kp3 17.7% PLERFEKALAFLKTM---GNEEIGIMGASTTGMLALVAASYFS-EIT--LTIAISPSDFVMEGFYQDGKDGAHERPGDGESSVSYHGKP--LPYLPY-AYRHPE---YWQKI-SEE---- consensus/100% ..phh....thh..........hsh.u.s.ss.hs..hs................................................................................. consensus/90% .hphhtpshphh.t....tt..hsh.uhshGuths..hssh....lt..ssl.hsss.h................................hs........................... consensus/80% .lEYFpcuhpalhpps..ptstlulhGhShGuplsh.hushh..tlp..sslhhsss.h.......................h..ps....ls.h...............t..h...... consensus/70% plEYFEcAhpaLhppP.hpsstlulhGhShGuplsL.hushhp.tlp..AsVslsssss..................t.hssh.hps....lP.ls............s.ph.hph.... 1 9eury-c1vei1 100.0% ----PLGGSVSLRPTYEVGLEQASTERISEATIPVENI--DGPVTLV---------------SGGDDRLWPSATFGRMVVRRLRNHEHPYP--------------------VRHVTTETA 2 pelts-a5czq3 38.2% ----AKKEPWSTAPLYEYALQ--NQEAVEKATIKVENI--NGPVLLV---------------SGGRDGAWPSGKMAEMIMQRLREKGHPFP--------------------DMHLHYRDA 3 bora1-q2l1v4 33.8% --FDDGPAPHRHERAILTALQ--DPDAVARARIPVERI--QGPVMLL---------------SATDDGSWPSSLYSGMVRDKLAEVSHPHE--------------------VQWLDFQDA 4 ralso-RSC1887 33.2% --FDEGEPPHRHERAIRTALR--DAQAVERARIRVEQT--RGPVLLL---------------SATDDGSWPSSDYARMAAARLAEARHPYP--------------------VVHHDFAGA 5 borbr-q7wk25 27.0% --AYASDPPYRQTHAFMSASR--DARAFERARIPIERY--PGPLMLI---------------SASDDGFWPSTAYSEIVARQRQAAWPARP--------------------AEHYVCRGA 6 bacld-q65ly2 30.1% ----LTRQPHAFLDLYQKALR--KVKDDHPAIIKAELI--KGPILLT---------------SSTDDLVWPSASMNEKIEERLKKNRFSYS--------------------VKHLYFEKA 7 solus-q43mm3 28.8% -----------------------PPELVARAAIEAERT--HGPILMI---------------SGEDDHLWRSWEMADNVVARLKRAHFPYR--------------------FENLKYPHA 8 cloac-CAC3407 25.5% LTDKLHGRTINFSKLYTNAIK--NPDAIETYMIPIENT--NGSILML---------------SGDNDHIWPSSKLCKLGIERLKQHNFSFY--------------------YDFLEY-KA 9 clob8-a6lt95 25.6% ----MIGNKEPMAWMYRKLIED---GNAYEAMIPVEKI--NGPILMA---------------SSLKDKIWPSKTHCEIIVELLRKAHFKHE--------------------YKHITYEKS 10 strmu-SMU.633 21.7% -----------QRLILKKDLK----NINHQAVIPVEKI--NGSLLLL---------------VSKKDEVWDAYGSAITIVNRLQQKRFKYP--------------------YQVESYENC 11 9flao-q1vpk2 21.0% ----TGGKAQVQLPYMLSAFE--KTKRIEKSSIKIENI--KCPILLI---------------SGEDDLQWPSTMMSNRIKARAEKYKFNYE--------------------IKHYSYENA 12 danre-q5rh34 20.4% ----NEDNHLIHRNTIL------PIPSDPALKVDVGRI--KCPLLLV---------------NGTDDQNWATVESAEDMEMMMKKAGNRQL--------------------LTVLTYPDA 13 danre-q5rhg5 17.9% ----NEDKHIVTREIIL------PIPSDPALKADVGRI--KCPLLLV---------------NGTDDQNWATNESAEDIKMMMEKAGNRHL--------------------LTVLTYPDA 14 danre-q6ph28 17.0% ----NEDNHLIHRDTIL------PIPSDPDLKVDAGRI--KCPIMLV---------------NGTDDQNWATVESAQDIEMIMEKAGNRHL--------------------LTVFTYPDA 15 danre-q5rhg4 17.5% ----NEDNHLIHRDMLL------PIPSDPALKVDVGRI--KCPLLLV---------------NGTDDQNWPTVESAEDIEMIMEKAGNRHL--------------------LTVLTYPDA 16 danre-q5rh35 18.9% ----NEDNHVIQRGMIL------PIPSDPAQKIDVGRI--KCPVMLV---------------NGGDDQNWASVESAQDMEMMMEKAGNRHL--------------------LTVLTYPDA 17 danre-q5u3w6 20.0% ----DEKMRIIWRDLLL------PIPDDPSQKVKMSEI--KCPVLLI---------------AGEDDQNWPASESAADMRKMMEKAGNSHL--------------------LTVLSYPGT 18 danre-q5spg7 19.5% ----TPLGLVDMLDVVKDPMS----KEGLPSVIPIERA--PGRFMFI---------------ASEANMNWRSAYHAKLACDRLKAHGKKN---------------------YELVKYEKA 19 danre-q5spg8 20.3% ----TPLGLVDIGEVMDDPMS----KEGLPSVIPIERA--PGSFMFV---------------VSEADRNWRSAYYAKLACDRLKAHGKNN---------------------YQLVKYEKA 20 danre-q6gmj5 19.3% ----TALGLVDMLEVVNDPMS----KEGLPTVIPIERA--SASFMFI---------------ASEADMNWRSVYHAKLACDRLKAHGKNN---------------------YELVKYEKA 21 tetng-q4rqz6 22.0% ----TDSGLVDIRDALPDPSS----EQSKASIFPIERA--SCRFLFA---------------ASEDDHNWNSVTSAKYAAAVLKDHGKEA---------------------FELVTYPKA 22 human-ACOT1 22.5% ----TKDGYADIVDVLNSPLE----GPDQKSFIPVERA--ESTFLFL---------------VGQDDHNWKSEFYANEACKRLQAHGRRK---------------------PQIICYPET 23 human-ACOT2 19.9% ----TKDGYADIVDVLNSPLE----GPDQKSFIPVERA--ESTFLFL---------------VGQDDHNWKSEFYANEACKRLQAHGRRK---------------------PQIICYPET 24 macfa-q4r4j8 20.7% ----TKDGYADIVDVLNSPLE----GPDQKSFIPVERA--ESTFLFL---------------VGQDDHNWKSEFYANEACKRLQAHGGRK---------------------PQIICYAGA 25 mouse-acot1 22.2% ----TKDGLKDVVDALQSPL------VDKKSFIPVERS--DTTFLFL---------------VGQDDHNWKSEFYADEISKRLQAHGKEK---------------------PQIICYPAA 26 ratno-acot1 22.0% ----TKDGLKDVVDALQSPL------VEQKSFIPVERS--DTTFLFL---------------VGQDDHNWKSEFYANEISKRLQAHGKEK---------------------PQIICYPEA 27 mouse-acot2 20.0% ----TKDGLLDVVEALQSPL------VDKKSFIPVERS--DTTFLFL---------------VGQDDHNWKSEFYADEISKRLQAHGKEK---------------------PQIICYPAA 28 ratno-acot2 20.7% ----TKDGLLDVVEALQSPL------VDKKSFIPVERS--DTTFLFL---------------VGQDDHNWKSEFYAREASKRLQAHGKEK---------------------PQIICYPEA 29 mouse-acot3 21.9% ----TKDGLKDIVDLLNNPLE----GPDQKSLIPVERS--DTAFLFL---------------VGQDDHNWKSEFYAREASKRLQAHGKEK---------------------PQIICYPET 30 mouse-acot5 23.4% ----TKDGFKDIIDILNVPLE----APDQKSLIPLERS--DTAFLFL---------------VGQDDHNWKSEFYAREASKRLQAHGKEK---------------------PQIVCYPKT 31 human-ACOT6 21.3% ----TKSGFLTFMDTWSNPLE----EHNHQSLVPLEKA--QVPFLFI---------------VGMDDQSWKSEFYAQIASERLQAHGKER---------------------PQIICYPET 32 mouse-ACOT6 23.1% ----NKSGLMDLRDMWNNPLE----EPNHQSLIPLEKA--QGPFLFL---------------VGMDDHNWKSDVYARIACERLQAHGKDR---------------------PQIIYYPET 33 human-ACOT4 22.0% ----AFSGLVDIVDIRNALVG----GYKNPSMIPIEKA--QGPILLI---------------VGQDDHNWRSELYAQTVSERLQAHGKEK---------------------PQIICYPGT 34 mouse-acot4 20.2% ----AFSGILDIVDIRNDAVG----GCENPSMIPIEKA--KGPILFV---------------AGQDDHCWRSELYTQIASDRLQAHGKER---------------------PQVLSYPGT 35 xenla-q6ntq4 23.2% ----PQPGVADISNVLNNPLE----EPNRASLIPLGRA--DSKFLFI---------------VGQEDKNWKSDFFAKIACDLLTEQGKEK---------------------PEVVCYPGA 36 human-BAAT 20.2% ----NALGLLELYRTFETTQV-----GASQYLFPIEEA--QGQFLFI---------------VGEGDKTINSKAHAEQAIGQLKRHGKNN---------------------WTLLSYPGA 37 mouse-BAAT 23.1% ----NALGLVEFYRTFQETAD-----KDSKYCFPIEKA--HGHFLFV---------------VGEDDKNLNSKVHANQAIAQLMKNGKKN---------------------WTLLSYPGA 38 ratno-BAAT 23.1% ----NALGLVEFYRTFEETAD-----KDSKYCFPIEKA--HGHFLFV---------------VGEDDKNLNSKVHAKQAIAQLMKSGKKN---------------------WTLLSYPGA 39 mouse-acnt1 24.3% ----HVSGAVCFRHTTQYLQN--------KNILPVEKA--QGKILFI---------------VGENDELLDSKLHAQRAMDRLRRHGRSS---------------------GRMLAYPGA 40 mouse-Q8BGG9 21.4% ----HDSGALLFRYTTQYLHN----KLNSQNILPVEKA--QGKILFI---------------VGENDECLDSKLHAQKAMDRLQRHGRSS---------------------GRMLAYPGA 41 ratno-q5fvr5 23.0% ----HGSGAACFRHCWD-PQN----MLNPPKILPVEKA--QGKILFI---------------VGENDQCLASKLHAQRAMDRLRSHGRSS---------------------GRMLAYPGA 42 caebr-A8WW80 18.8% --CQFINGVMCSHRNFQIMTE----KLTPETEIPWSRIPTDVKIRVLVSDFSRIT-VLIIFQGSVDDLCQPSVHATLYRQRRLKETGHDVE-VRVQKYILEFIQNQKK--FVFQVEMVNG 43 caeel-W03D8.8 18.1% --CQFINGVMCSHRNFQIMTE----KLTPETEIPWERIPSDVKIRVIVSVRADVQRKFCELQGSVDDLCQPSVHATYYRQRRLKETGHDVETVKVPSDVFFFNRNSENNPINSEVELVNG 44 caebr-A8XFE8 16.7% ----FINTILATAPCFKTLTP----VLTPETSIPWHRIPKDTAYRLI---------------GSVDDLCAPSIHSNLHIQKKLQETGHYVE-----------------------LELVNG 45 caeel-C31H5.6 17.9% ----FLNTILVTAPCFKTLTP----ILTEENSIPWHWIPKETAFRLI---------------GSVDDLCAPSIHSNLHIQKKLQETGHYVE-----------------------LELVNG 46 caebr-A8XG15 18.5% ----FINGVLRQKPAFNDLYS----KLTPTTSIPWWRASKDTVYRIV---------------QCYDDMLVDGVPSRDNICKNLKETGHSVE-----------------------SELVPG 47 caeel-T05E7.1 17.5% ----FVNQVLRQKPAFRDLYS----NLTPTTSIPWARAPKNTAYRIV---------------QCYDDMLVDAVPSIINICGNLRKTGHHVE-----------------------SELVPG 48 caebr-a8xk76 16.9% --VKFLNDLMVYTDM-----------------------------------------------SALDDLSTPTIYANSYLSARLRDAGRKFE-----------------------VNFVPG 49 caeel-K05B2.4 17.2% --IWYLNDLMVYTDMVRNL------KLEDGAGFKFEDSSPETAFRFS---------------LAVDDLSTPTVFVGKVLSEKLRNLNRKVE-----------------------VHYVSG 50 agrtu-ATU3652 21.5% ----YRDGLVSYRSFFEKCLSN-DVQLNERARIPVESS--PADLILV---------------AGGDDALWPSGYFARQILQSRQAHGRQ----------------------ATLIFDKDA 51 rhil3-q1mg17 23.2% ----YRDELVAYRGLFERCLQV-HQSEIDAAAIPLEKT--NAEILLV---------------AGCDDALWPSDKFAASLVRRRAASGLL----------------------TQLVLGEDA 52 rhilo-MLR4383 23.7% ----HVDGLVSYRGLFQHCLAS-FGQEADRAAIPVEAI--SAKLVLV---------------AGGDDALWPSLDFAQSIVRRREDAGKA----------------------TRLVSSPDA 53 9sphn-q2n9j1 22.1% ----GPNGRARLRLPHDRGRNA-NPDRAVAARIPVERI--DEPVLVA---------------GGDADLVWNSGEMAQIVAERRAAAGLP----------------------TVSLIFTDA 54 strmu-SMU.1678 20.2% --NFLIKTPISYYHTYKQALD--KDKNSEDKRIKVEKT--KANILIF---------------AGENDRMWPSAESARLI----EKYQPNH---------------------TQVTIYKEA 55 trede-q73kp3 17.7% --TKRRGAMVASRDLFDESEK--RHPVQEAEKIKVENI--KGRILLI---------------GAEDDVLWDTCKYIRRMENRLKERDADNS--------------------VVLMTYEHG consensus/100% ...............................................................s.ts....s......h.....t..................................s consensus/90% .......t.h..h.hh................h.htp...ps.hhhh...............su.sD..h.o...s..h...htttt...........................h.h.ts consensus/80% ......tshh.hh.hh...........t.tthlshcch..ps.hhhl...............sutcDh.h.S...sp.h.tphpttstp.......................phlpa.tu consensus/70% ....hhsshhthhphhpt.ht......s.tshIPlE+h..psshlhl...............supDDtsW.S.hhup.htppLpttGpph......................phlpYstu 1 9eury-c1vei1 100.0% GHAIS-FPYQPTTG--LTAISSPPPG---TTMALGG-SPEGLA-RANKESWPVVLSTLEGGLS--------------------------------------------------------- 2 pelts-a5czq3 38.2% GHQIS-TPYSPTT----VYWLTLPGG---FIEDLGG-TPEGNA-AASMDSWPKIIDFFARHLGGKQ------------------------------------------------------ 3 bora1-q2l1v4 33.8% GHLIV-FPYVPTT---QMVYAHPVSG---KISTSGG-NPKDNA-RADEESWAGVLQFLHDAVAKAAE----------------------------------------------------G 4 ralso-RSC1887 33.2% GHAIV-FPYVPTT---QLVHAHPVSG---RISTGGG-EPRANA-RADLQSWAAVRRFLAEAVA--------------------------------------------------------- 5 borbr-q7wk25 27.0% GHHVH-YPNLPAT---LISKPHAMSG---LLLDAGG-TPPANA-HGNAGSYRAMLDFLERARAS-------------------------------------------------------- 6 bacld-q65ly2 30.1% GHNIR-PPYFPTS------------GRKSRKIAYGG-KTEYDA-IAAQTFWQELLLFLEKATAPGN------------------------------------------------------ 7 solus-q43mm3 28.8% GHSAG-RPGIQPAW--HGAVHNPTSV---RENDLGG-SAKGDA-QSTLDSMPKVIEFLTASTRE-------------------------------------------------------- 8 cloac-CAC3407 25.5% GHHIY-FPYQPIY-------------------KYNG-SNENMA-ISNRESWNKILEFLQK------------------------------------------------------------ 9 clob8-a6lt95 25.6% GHMLT-VPYQSIY----------------PSNKYPD-DIDGFA-KANINCWNETINFIDKWSRQ-------------------------------------------------------- 10 strmu-SMU.633 21.7% GHMMT-VAYQPNH-------------------RYKKVALEKIM-ADTNDSWQKTLVFFRNRL---------------------------------------------------------- 11 9flao-q1vpk2 21.0% GHQFDDLPFIPQLDFS-----------NISTWKSGG-NFQGNA-LASIDSWNRIFIFLNKQLGT-------------------------------------------------------I 12 danre-q5rh34 20.4% GHLIE-PPYTPHFRATNFLLHKMNEK---VVMLWGG-QTKPHA-YAQEDSWKKILAFFREHLYGSSVK---------------------------------------------------A 13 danre-q5rhg5 17.9% GHLIE-PPYTPHFRATNFLLHDMKVK---VVMLWGG-QTKPHA-YAQEDSWKKILAFFHEHLYGSNVK---------------------------------------------------A 14 danre-q6ph28 17.0% GHLIE-PPYTPHFRATNVLLHK-KEK---VVMLWGG-QTKPHA-YAQEDSWEKILAFFQEHLYSSNVK---------------------------------------------------A 15 danre-q5rhg4 17.5% GHLIE-PPYTPHFRASNFILYDTKKK---VVMLWGG-QTKPHA-YAQEDSWKKILAFLQEHLYSSNVK---------------------------------------------------A 16 danre-q5rh35 18.9% GHLIE-PPYTPHFRATNFILQEMKEK---IVMLWGG-QTKPHA-YAQEDSWEKILAFFHQHLYSSNIR---------------------------------------------------A 17 danre-q5u3w6 20.0% GHLIE-PPYSPHVRFSDFKLLEAKTK---VVVLWGG-ETEPHS-RAQEESWKKTLAFLEEHLYGNSREV--------------------------------------------------T 18 danre-q5spg7 19.5% GHFIE-VPYMPFC----FANFHSVLK---QPVLFGG-EPKCHS-EAQVDAWPRIINFFKKHLATADYNLSP------------------------------------------------- 19 danre-q5spg8 20.3% GHFIE-VPYMPFC----LANFHGVAG---QPVFFGG-EPKAHA-EAQLDAWPKMINFFKKHLAATDHNPR-------------------------------------------------S 20 danre-q6gmj5 19.3% GHFIE-VPYMPFC----LAAFHGVLE---QPVLFGG-EPKAHS-EAQVDAWQRIIIFFKRTLGS-------------------------------------------------------- 21 tetng-q4rqz6 22.0% GHFLE-VPHMPFC----ASGFHAAVG---TNVVFGG-EPKAHC-EAQIHLWEKVQEFFGAHLG--------------------------------------------------------- 22 human-ACOT1 22.5% GHYIE-PPYFPLC----RASLHALVG---SPIIWGG-EPRAHA-MAQVDAWKQLQTFFHKHLGGHEGTIP-------------------------------------------------S 23 human-ACOT2 19.9% GHYIE-PPYFPLC----RASLHALVG---SPIIWGG-EPRAHA-MAQVDAWKQLQTFFHKHLGGREGTIP-------------------------------------------------S 24 macfa-q4r4j8 20.7% GHYIE-PPYFPLC----RASLHALVG---SAIIFGG-EPRAHA-MAQVDAWKQLQTFFHKHLGGQEGTIP-------------------------------------------------A 25 mouse-acot1 22.2% GHYIE-PPYFPLC----SAGMHLLVG---ANITFGG-EPKPHA-MAQLDAWQQLQTFFHKQLGSECLHVS-------------------------------------------------P 26 ratno-acot1 22.0% GHYIE-PPYFPLC----SAGMHLLVG---ANITFGG-EPKPHS-VAQLDAWQQLQTFFHKQLGGKSHGVS-------------------------------------------------P 27 mouse-acot2 20.0% GHYIE-PPYFPLC----SAGMHLLVG---ANITFGG-EPRAHA-VAQVDAWQQLQTFFHKQLGSKS------------------------------------------------------ 28 ratno-acot2 20.7% GHYIE-PPYFPLC----SAGMHLLVG---ANITFGG-EPKPHS-VAQLDAWQQLQTFFHKQLSGKS------------------------------------------------------ 29 mouse-acot3 21.9% GHHIE-PPYFPLC----KASLNSLVG---GPVIWGG-EPRAHA-MAQVDAWQQLQTFFHNHLDGKKKTIP-------------------------------------------------A 30 mouse-acot5 23.4% GHHIE-PPYIPWS----IAAPHSYFD---KPILLGG-EPRAHA-MAQVDAWQRLQTFFHKHLSGDKRPSP-------------------------------------------------A 31 human-ACOT6 21.3% GHCID-PPYFPPS----RASVHAVLG---EAIFYGG-EPKAHS-KAQVDAWQQIQTFFHKHLNGKKSVKH-------------------------------------------------S 32 mouse-ACOT6 23.1% GHCIE-PPYFPPP----IATVHFVLG---EAVFNGG-KPRAQS-RAQLDAWQRIQTFFQKYLNGEKPARH-------------------------------------------------S 33 human-ACOT4 22.0% GHYIE-PPYFPLC----PASLHRLLN---KHVIWGG-EPRAHS-KAQEDAWKQILAFFCKHLGGTQKTAV-------------------------------------------------P 34 mouse-acot4 20.2% GHYIE-PPYFPMC----PASLHKIVN---EAVIWGG-EVKAHS-KAQIDAWKQILFFFGKHLGSTHSRAS-------------------------------------------------C 35 xenla-q6ntq4 23.2% GHYIE-PPYFPLC----KASMHRLVG---FPVIWGG-EMKAHA-MAQVDSWHRIQAFLHKHLDQ-------------------------------------------------------- 36 human-BAAT 20.2% GHLIE-PPYSPLC----CASTTHD-----LRLHWGG-EVIPHA-AAQEHAWKEIQRFLRKHLIPDVT----------------------------------------------------S 37 mouse-BAAT 23.1% GHLIE-PPYTPLC----QASRMPILI---PSLSWGG-EVIPHSQAAQEHSWKEIQKFLKQHLLPDLS----------------------------------------------------S 38 ratno-BAAT 23.1% GHLIE-PPYSPLC----SASRMPFVI---PSINWGG-EVIPHA-AAQEHSWKEIQKFLKQHLNPGFN----------------------------------------------------S 39 mouse-acnt1 24.3% GHLIE-PPYSPLC----FASWQPVLG---RPMCFGG-DLMAHA-AAQEHSWREIQKFFRKHLLQSG-----------------------------------------------------S 40 mouse-Q8BGG9 21.4% GHLIE-PPYSPVC----FVAWFPVLG---QPMCFGG-DLMAHA-AAQEHSWREIQKFFRKHLLQSG-----------------------------------------------------S 41 ratno-q5fvr5 23.0% GHLIE-PPYSPFC----FACWDSVLG---KPMLWGG-DPIAHA-AAQVHSWREIQKFFRQHLLQSG-----------------------------------------------------G 42 caebr-A8WW80 18.8% GHIME-PPYFPHH----ELVYAKYQG---FYCGYGG-EVLLHA-KSQEKTWANSIKFFQRALGKTKHIEDWQRLELILPPRG------------------------------------ES 43 caeel-W03D8.8 18.1% GHIME-PPYFPHH----ELVYAKYQG---FYCGYGG-EVVLHA-KSQEKTWSNTIKFFQKALGNTKKIQDWDRLTVVVPPRK------------------------------------KS 44 caebr-A8XFE8 16.7% GHIME-PPYFPHH----DIVYAKFQG---FYCGYGG-EIVLHA-KSQERTWANTINFFKRKLGSPPPMPDWMRLTKVDGPLRPITI-------------------------------HKP 45 caeel-C31H5.6 17.9% GHIME-PPYFPHH----DIVYAKFQG---FYCGYGG-EIVLHA-KSQERTWANTINFFKRKLGSPPPMPDWTRLFIVNAPLKPIE--------------------------------NRS 46 caebr-A8XG15 18.5% GHFLY-FPYFPHH----GIIYNAQIN---LMWGFGG-ECYQHS-KSQETTWAKNVEFFRKHLGRGTKIPDWNRETRVSLPNSESIAQTNRQLVLRSPNHMEHFRSIQQHRRPDASSETKS 47 caeel-T05E7.1 17.5% GHFLY-FPYFPHH----GIIYNAQIN---MLWGFGG-ECYQHS-KSQETTWKKNVEFFKKHLGDVKRIPEWKRESTVTLPVSTKSSKS-----------------------------LQC 48 caebr-a8xk76 16.9% GHLLD-PPCFPHH----PMVYSNIAG---LFQTYGG-DTSLHG-RSEFEVWERTVRFFSEHLGAPTPLPDYLRHS--------------------------------------------A 49 caeel-K05B2.4 17.2% GHLLD-PPCFPHH----EAVFSAFAG---TFQAYGG-ETSLHG-KSQFEVWEKTVQFFSEHLGAPTPLPDYSRHL--------------------------------------------A 50 agrtu-ATU3652 21.5% GHRIL-LPGETTQ--------------RSKLHAHGG-SDEADA-KLGQNAWRAIRELL-------------------------------------------------------------- 51 rhil3-q1mg17 23.2% GHRIL-LPGETTP--------------RSSLRAHGG-SDEADA-QLGRLAWEHILEML-------------------------------------------------------------- 52 rhilo-MLR4383 23.7% GHRIL-LPGETTP--------------RSALHAHGG-NDHADA-RLGRDAWELIRDLL-------------------------------------------------------------- 53 9sphn-q2n9j1 22.1% GHSLS-GDGTPNPY-----------------------SNDEEL-SAQRIVWPATLEFFATYLKD-------------------------------------------------------- 54 strmu-SMU.1678 20.2% GHLFA-GDGIVDS-----------RG---IYLSVGG-NKAANE-TAKKDSDQRLKKQLSIWHS--------------------------------------------------------- 55 trede-q73kp3 17.7% THFIF-----PQTML--TGILPVGSG---LFISMAFKEAKQYP-KECKQTRIEVDERLSEELKQWINSAR-------------------------------------------------- consensus/100% sH.h.................................t........t..........h.............................................................. consensus/90% GHhh...Ph.s......................hGG.p...pu..up.psW.th.thhtt.h.......................................................... consensus/80% GHhlp..Pa.Phh..................hhhGG.ps..pu.hup.csWtph.tFhpptL.......................................................... consensus/70% GHhIc.sPYhPhp.....h.ht.h.t.....hhaGG.pspsau.hAp.cuWppl.pFhpcpLtt........................................................ 1 9eury-c1vei1 100.0% ------------------------------------------------------------- 2 pelts-a5czq3 38.2% ------------------------------------------------------------- 3 bora1-q2l1v4 33.8% EA----------------------------------------------------------- 4 ralso-RSC1887 33.2% ------------------------------------------------------------- 5 borbr-q7wk25 27.0% ------------------------------------------------------------- 6 bacld-q65ly2 30.1% ------------------------------------------------------------- 7 solus-q43mm3 28.8% ------------------------------------------------------------- 8 cloac-CAC3407 25.5% -L----------------------------------------------------------- 9 clob8-a6lt95 25.6% DI----------------------------------------------------------- 10 strmu-SMU.633 21.7% ------------------------------------------------------------- 11 9flao-q1vpk2 21.0% ELN---------------------------------------------------------K 12 danre-q5rh34 20.4% KL----------------------------------------------------------- 13 danre-q5rhg5 17.9% KL----------------------------------------------------------- 14 danre-q6ph28 17.0% KL----------------------------------------------------------- 15 danre-q5rhg4 17.5% KL----------------------------------------------------------- 16 danre-q5rh35 18.9% KL----------------------------------------------------------- 17 danre-q5u3w6 20.0% RM----------------------------------------------------------- 18 danre-q5spg7 19.5% ------------------------------------------------------------- 19 danre-q5spg8 20.3% ML----------------------------------------------------------- 20 danre-q6gmj5 19.3% ------------------------------------------------------------- 21 tetng-q4rqz6 22.0% ------------------------------------------------------------- 22 human-ACOT1 22.5% KV----------------------------------------------------------- 23 human-ACOT2 19.9% KV----------------------------------------------------------- 24 macfa-q4r4j8 20.7% KL----------------------------------------------------------- 25 mouse-acot1 22.2% KI----------------------------------------------------------- 26 ratno-acot1 22.0% KI----------------------------------------------------------- 27 mouse-acot2 20.0% ------------------------------------------------------------- 28 ratno-acot2 20.7% ------------------------------------------------------------- 29 mouse-acot3 21.9% KL----------------------------------------------------------- 30 mouse-acot5 23.4% KL----------------------------------------------------------- 31 human-ACOT6 21.3% KI----------------------------------------------------------- 32 mouse-ACOT6 23.1% KL----------------------------------------------------------- 33 human-ACOT4 22.0% KL----------------------------------------------------------- 34 mouse-acot4 20.2% RL----------------------------------------------------------- 35 xenla-q6ntq4 23.2% ------------------------------------------------------------- 36 human-BAAT 20.2% QL----------------------------------------------------------- 37 mouse-BAAT 23.1% QL----------------------------------------------------------- 38 ratno-BAAT 23.1% QL----------------------------------------------------------- 39 mouse-acnt1 24.3% KL----------------------------------------------------------- 40 mouse-Q8BGG9 21.4% KL----------------------------------------------------------- 41 ratno-q5fvr5 23.0% KL----------------------------------------------------------- 42 caebr-A8WW80 18.8% KL----------------------------------------------------------- 43 caeel-W03D8.8 18.1% KL----------------------------------------------------------- 44 caebr-A8XFE8 16.7% KMLYTIAAVGACAYFAVTDSIVKKAVVETVKAVVWPTSDEQVAAQMKEKKTDKEDEDWALY 45 caeel-C31H5.6 17.9% RL----------------------------------------------------------- 46 caebr-A8XG15 18.5% KL------------------------------------------------------DLKKY 47 caeel-T05E7.1 17.5% KL----------------------------------------------------------- 48 caebr-a8xk76 16.9% KL----------------------------------------------------------- 49 caeel-K05B2.4 17.2% KL----------------------------------------------------------- 50 agrtu-ATU3652 21.5% ------------------------------------------------------------- 51 rhil3-q1mg17 23.2% ------------------------------------------------------------- 52 rhilo-MLR4383 23.7% ------------------------------------------------------------- 53 9sphn-q2n9j1 22.1% ------------------------------------------------------------- 54 strmu-SMU.1678 20.2% ------------------------------------------------------------- 55 trede-q73kp3 17.7% ------------------------------------------------------------- consensus/100% ............................................................. consensus/90% ............................................................. consensus/80% ............................................................. consensus/70% ............................................................. |
MView 1.56, Copyright © 1997-2013 Nigel P. Brown
#protein: highlight amino acid physicochemical properties
hydrophobic => bright-green { A, G, I, L, M, P, V }
large hydrophobic => dark-green { F, H, W, Y }
cystein => yellow { C }
negative charge => bright-blue { D, E }
positive charge => bright-red { K, R }
polar => purple { N, Q }
small alcohol => dull-blue { S , T }
any => dark-gray { X }
#protein consensus: report conserved physicochemical classes, derived from the Venn diagrams of Taylor W. R. (1986).
# The classification of amino acid conservation.
#J. Theor. Biol. 119:205-218.
alcohol => o { S, T }
aliphatic => l { I, L, V }
aromatic => a { F, H, W, Y }
charged => c { D, E, H, K, R }
hydrophobic => h { A, C, F, G, H, I, K, L, M, R, T, V, W, Y }
negative => - { D, E }
polar => p { C, D, E, H, K, N, Q, R, S, T }
positive => + { H, K, R }
small => s { A, C, D, G, N, P, S, T, V }
tiny => u { A, G, S }
turnlike => t { A, C, D, E, G, H, K, N, Q, R, S, T }