2016

Yin_2016_Catal.Sci.Technol_6_6305 Green access to chiral Vince lactam in a buffer-free aqueous system using a newly identified substrate-tolerant (-)-gamma-lactamase
Hong_2016_J.Mol.Catal.B.Enzym_133_S337 Gene cloning and characterization of a psychrophilic phthalate esterase with organic solvent tolerance from an Arctic bacterium Sphingomonas glacialis PAMC 26605
Wongwatanapaiboon_2016_Biosci.Biotechnol.Biochem_80_2231 Cloning, expression, and characterization of Aureobasidium melanogenum lipase in Pichia pastoris
Dilokpimol_2016_Biotechnol.Biofuels_9_231 Diversity of fungal feruloyl esterases: updated phylogenetic classification, properties, and industrial applications
Wang_2016_Appl.Biochem.Biotechnol_180_1196 Functional Characterization of a Robust Marine Microbial Esterase and Its Utilization in the Stereo-Selective Preparation of Ethyl (S)-3-Hydroxybutyrate
Wang_2016_Chin.J.Catal_37_1396 Characterization of a novel marine microbial esterase and its use to make D-methyl lactate
Yu_2016_BMC.Genomics_17_654 Seminal fluid protein genes of the brown planthopper, Nilaparvata lugens
Li_2016_J.Biotechnol_228_30 Cloning and characterization of a novel lipase from Stenotrophomonas maltophilia GS11: The first member of a new bacterial lipase family XVI
Flaugnatti_2016_Mol.Microbiol_99_1099 A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery
Tomihama_2016_Genome.Announc_4_e00062 Draft Genome Sequences of Streptomyces scabiei S58, Streptomyces turgidiscabies T45, and Streptomyces acidiscabies a10, the Pathogens of Potato Common Scab, Isolated in Japan
de Saint Germain_2016_Nat.Chem.Biol_12_787 An histidine covalent receptor and butenolide complex mediates strigolactone perception
Bi_2016_Sci.Rep_6_21162 A Biotin Biosynthesis Gene Restricted to Helicobacter
Iwata_2016_J.Biosci.Bioeng_122_140 Re-characterization of mono-2-ethylhexyl phthalate hydrolase belonging to the serine hydrolase family
Petrovskaya_2016_FEMS.Microbiol.Ecol_92_ Expression and characterization of a new esterase with GCSAG motif from a permafrost metagenomic library
Ye_2016_Catal.Commun_87_32 Directed modification of a novel epoxide hydrolase from Phaseolus vulgaris to improve its enantioconvergence towards styrene epoxides
Zarafeta_2016_Sci.Rep_6_38886 Metagenomic mining for thermostable esterolytic enzymes uncovers a new family of bacterial esterases
Tao_2016_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_203_100 Cloning of two carboxylesterase cDNAs from the swimming crab Portunus trituberculatus: Molecular evidences for their putative roles in methyl farnesotae degradation
Kono_2016_Mol.Ecol.Resour_16_662 Evaluation of the impact of RNA preservation methods of spiders for de novo transcriptome assembly
You_2016_Parasit.Vectors_9_328 Functional characterisation of Schistosoma japonicum acetylcholinesterase
Cruz_2016_Gigascience_5_29 Genome sequence of the olive tree, Olea europaea
Hashimoto_2016_Nat.Commun_7_12808 Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein
Anantharaman_2016_Nat.Commun_7_13219 Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system
Grijseels_2016_Sci.Rep_6_35112 Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites
Moore_2016_Genome.Biol.Evol_8_3297 Draft Genome Sequence of an Aflatoxigenic Aspergillus Species, A. bombycis
Hunt_2016_Nat.Genet_48_299 The genomic basis of parasitism in the Strongyloides clade of nematodes
Small_2016_Mol.Ecol_25_1465 Population genomics of the filarial nematode parasite Wuchereria bancrofti from mosquitoes
Niehaus_2016_Genome.Biol.Evol_8_3574 Comparative Omics of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis
Session_2016_Nature_538_336 Genome evolution in the allotetraploid frog Xenopus laevis
Sayed_2016_J.Biotechnol_221_62 Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245
Yan_2016_MBio_7_e02104 Strain Prioritization and Genome Mining for Enediyne Natural Products
Butterfield_2016_PeerJ_4_E2687 Proteogenomic analyses indicate bacterial methylotrophy and archaeal heterotrophy are prevalent below the grass root zone
Ercibengoa_2016_Antonie.Van.Leeuwenhoek_109_653 Nocardia donostiensis sp. nov., isolated from human respiratory specimens
Al-Wathiqui_2016_Sci.Rep_6_38556 Molecular characterization of firefly nuptial gifts: a multi-omics approach sheds light on postcopulatory sexual selection
Deng_2016_Appl.Biochem.Biotechnol_180_228 Functional Characterization of a Novel Dactylosporangium Esterase and Its Utilization in the Asymmetric Synthesis of (R)-Methyl Mandelate
Tong_2016_Biotechnol.Appl.Biochem_63_471 Characterization of a new sn-1,3-regioselective triacylglycerol lipase from Malbranchea cinnamomea
De Santi_2016_PLoS.One_11_e0159345 Biochemical Characterization of a Family 15 Carbohydrate Esterase from a Bacterial Marine Arctic Metagenome
Hagstrom_2017_Arch.Toxicol_91_2837 Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation
Hagstrom_2016_Regeneration.(Oxf)_3_65 Planarian brain regeneration as a model system for developmental neurotoxicology
Yoshida_2016_Science_351_1196 A bacterium that degrades and assimilates poly(ethylene terephthalate)
Tanasupawat_2016_Int.J.Syst.Evol.Microbiol_66_2813 Ideonella sakaiensis sp. nov., isolated from a microbial consortium that degrades poly(ethylene terephthalate)
Yang_2016_Science_353_759 Comment on A bacterium that degrades and assimilates poly(ethylene terephthalate)
Yoshida_2016_Science_353_759 Response to Comment on A bacterium that degrades and assimilates poly(ethylene terephthalate)
Rauwerdink_2016_Mol.Biol.Evol_33_971 Evolution of a Catalytic Mechanism
Cao_2016_Appl.Biochem.Biotechnol_180_210 Functional Characterization of a Novel Marine Microbial Esterase and its Utilization in the Enantioselective Preparation of (R)-Methyl 2-Chloropropionate
Lee_2016_Front.Microbiol_7_218 Isolation and Characterization of a Novel Cold-Adapted Esterase, MtEst45, from Microbulbifer thermotolerans DAU221
Wang_2016_Bull.Entomol.Res_106_615 Expression and characterization of a lipase-related protein in the malpighian tubules of the Chinese oak silkworm, Antheraea pernyi
de Oliveira_2016_Int.J.Biol.Macromol_89_569 Epoxide hydrolase of Trichoderma reesei: Biochemical properties and conformational characterization
Koseki_2016_J.Mol.Catal.B.Enzym_133_S560 An unusual feruloyl esterase from Aspergillus oryzae: two tryptophan residues play a crucial role for the activity
Chekan_2016_J.Am.Chem.Soc_138_16452 Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates
Yuan_2016_Biotechnol.Appl.Biochem_63_41 Screening and characterization of a thermostable lipase from marine Streptomyces sp. strain W007
Liu_2016_Sci.Rep_6_38137 Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis
Yan_2016_Appl.Environ.Microbiol_82_6748 Facilitating the Evolution of Esterase Activity from a Promiscuous Enzyme (Mhg) with Catalytic Functions of Amide Hydrolysis and Carboxylic Acid Perhydrolysis by Engineering the Substrate Entrance Tunnel
Fage_2016_Angew.Chem.Int.Ed.Engl_55_12717 Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase
Xu_2016_Sci.Rep_6_31386 Structural basis of unique ligand specificity of KAI2-like protein from parasitic weed Striga hermonthica
Meng_2016_PLoS.One_11_e0158011 Identification and Biochemical Properties of Two New Acetylcholinesterases in the Pond Wolf Spider (Pardosa pseudoannulata)
Jin_2016_Appl.Microbiol.Biotechnol_100_9163 Comparative genomic analysis identified a mutation related to enhanced heterologous protein production in the filamentous fungus Aspergillus oryzae
Huang_2016_Sci.Rep_6_28550 Structural insights of a hormone sensitive lipase homologue Est22
Oh_2016_J.Biol.Chem_291_15185 Structural Insights into an Oxalate-producing Serine Hydrolase with an Unusual Oxyanion Hole and Additional Lyase Activity
Gruninger_2016_Biochem.J_473_839 Contributions of a unique beta-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases
Drake_2016_Nature_529_235 Structures of two distinct conformations of holo-non-ribosomal peptide synthetases
Perz_2016_Biotechnol.Bioeng_113_1024 Hydrolysis of synthetic polyesters by Clostridium botulinum esterases
Tolzer_2016_FEBS.Lett_590_174 A novel esterase subfamily with alpha\/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases
Li_2016_J.Mol.Catal.B.Enzym_125_75 Rational selection of circular permutation sites in characteristic regions of the alpha\/beta-hydrolase fold enzyme RhEst1
Luan_2016_Ind.Eng.Chem.Res_55_12167 Dramatically Improved Performance of an Esterase for Cilastatin Synthesis by Cap Domain Engineering
De Santi_2016_Extremophiles_20_323 Biochemical characterization and structural analysis of a new cold-active and salt-tolerant esterase from the marine bacterium Thalassospira sp
Perz_2016_N.Biotechnol_33_295 Substrate specificities of cutinases on aliphatic-aromatic polyesters and on their model substrates
Shi_2016_Sci.Rep_6_18646 Functional Analysis of Esterase TCE2 Gene from Tetranychus cinnabarinus (Boisduval) involved in Acaricide Resistance
Kelle_2016_Biotechnol.Appl.Biochem_63_852 Heterologous production of a feruloyl esterase from Pleurotus sapidus synthesizing feruloyl-saccharide esters
Truongvan_2016_Biochemistry_55_3542 Flexibility and Stability Trade-Off in Active Site of Cold-Adapted Pseudomonas mandelii Esterase EstK
Wei_2016_Biotechnol.Bioeng_113_1658 Engineered bacterial polyester hydrolases efficiently degrade polyethylene terephthalate due to relieved product inhibition
Barth_2016_Biotechnol.J_11_1082 A dual enzyme system composed of a polyester hydrolase and a carboxylesterase enhances the biocatalytic degradation of polyethylene terephthalate films
Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus
Wang_2016_J.Biomol.Struct.Dyn_34_749 Exploration of the chlorpyrifos escape pathway from acylpeptide hydrolases using steered molecular dynamics simulations
Rittiroongrad_2016_PLoS.One_11_e0168791 Agrobacterium tumefaciens estC, Encoding an Enzyme Containing Esterase Activity, Is Regulated by EstR, a Regulator in the MarR Family
Wittenborn_2016_J.Biol.Chem_291_25264 Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator
Engdahl_2016_J.Med.Chem_59_9409 Discovery of Selective Inhibitors Targeting Acetylcholinesterase 1 from Disease-Transmitting Mosquitoes
Kim_2016_Plant.J_85_758 Molecular and biochemical characterizations of the monoacylglycerol lipase gene family of Arabidopsis thaliana
Zapata_2016_Proc.Natl.Acad.Sci.U.S.A_113_E4052 Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms
Gharat_2016_PLoS.One_11_e0163485 Transcriptome Analysis of the Response to NaCl in Suaeda maritima Provides an Insight into Salt Tolerance Mechanisms in Halophytes
Yao_2016_Nature_536_469 DWARF14 is a non-canonical hormone receptor for strigolactone
Jakobson_2016_New.Phytol_211_614 BODYGUARD is required for the biosynthesis of cutin in Arabidopsis
Vijayakumar_2016_Plant.Physiol_170_180 The Arabidopsis ABHD11 Mutant Accumulates Polar Lipids in Leaves as a Consequence of Absent Acylhydrolase Activity
Sayer_2016_Sci.Rep_6_25542 Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site
Upadhyay_2016_Cell.Rep_14_2511 Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin
Hu_2016_J.Biotechnol_236_152 Kinetic resolution of racemic styrene oxide at a high concentration by recombinant Aspergillus usamii epoxide hydrolase in an n-hexanol\/buffer biphasic system
Shirke_2016_Proteins_84_60 Toward rational thermostabilization of Aspergillus oryzae cutinase: Insights into catalytic and structural stability
Espinosa-Luna_2016_Mol.Biotechnol_58_37 Gene Cloning and Characterization of the Geobacillus thermoleovorans CCR11 Carboxylesterase CaesCCR11, a New Member of Family XV
Huang_2016_Appl.Biochem.Biotechnol_180_1467 Functional Characterization of a Marine Bacillus Esterase and its Utilization in the Stereo-Selective Production of D-Methyl Lactate
Khaleghinejad_2016_J.Genet.Eng.Biotechnol_14_83 Study the effect of F17S mutation on the chimeric Bacillus thermocatenulatus lipase
Malik_2016_Sci.Rep_6_38469 RNAi-mediated mortality of the whitefly through transgenic expression of double-stranded RNA homologous to acetylcholinesterase and ecdysone receptor in tobacco plants
Vekiru_2016_World.Mycotoxin.J_9_353 Isolation and characterisation of enzymatic zearalenone hydrolysis reaction products
Xu_2016_ACS.Catal_6_7657 Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering
Xiang_2016_Microbiol.Res_193_48 High-level expression of a ZEN-detoxifying gene by codon optimization and biobrick in Pichia pastoris
Wang_2016_Arch.Insect.Biochem.Physiol_93_110 Expression and effects of mutant Bombyx mori acetylcholinesterase 1 in BmN Cells
Wang_2016_Pestic.Biochem.Physiol_129_1 Effects of mutations on the structure and function of silkworm type 1 acetylcholinesterase
Jyoti_2016_Vet.Parasitol_216_108 Multiple mutations in the acetylcholinesterase 3 gene associated with organophosphate resistance in Rhipicephalus (Boophilus) microplus ticks from Punjab, India
Gui_2016_Mol.Cell.Probes_30_61 Association studies on the bovine lipoprotein lipase gene polymorphism with growth and carcass quality traits in Qinchuan cattle
Han_2016_Ecotoxicology_25_835 ace-3 plays an important role in phoxim resistance in Caenorhabditis elegans
Park_2016_ACS.Catal_6_7458 Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B
Strzelczyk_2016_Acta.Biochim.Pol_63_103 Crystal and molecular structure of hexagonal form of lipase B from Candida antarctica
Drozdz_2016_Chem.Commun.(Camb)_52_1230 Chemo-enzymatic Baeyer-Villiger oxidation of 4-methylcyclohexanone via kinetic resolution of racemic carboxylic acids: direct access to enantioenriched lactone
Jan_2016_Biochim.Biophys.Acta_1864_187 Elucidation of a key position for acyltransfer activity in Candida parapsilosis lipase\/acyltransferase (CpLIP2) and in Pseudozyma antarctica lipase A (CAL-A) by rational design
Point_2016_Eur.J.Med.Chem_123_834 Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis
Rodrigues_2016_Bioresour.Technol_218_1224 Biodiesel production from crude jatropha oil catalyzed by immobilized lipase\/acyltransferase from Candida parapsilosis in aqueous medium
Carlucci_2016_Protein.Sci_25_877 Biochemical characterization of two haloalkane dehalogenases: DccA from Caulobacter crescentus and DsaA from Saccharomonospora azurea
Nurizzo_2016_Acta.Crystallogr.D.Struct.Biol_72_966 RoboDiff: combining a sample changer and goniometer for highly automated macromolecular crystallography experiments
Wang_2016_Arch.Insect.Biochem.Physiol_93_129 Molecular characterization of two acetylcholinesterase genes from the rice leaffolder, Cnaphalocrocis medinalis (Lepidoptera: pyralidae)
Johnson_2016_Pest.Manag.Sci_72_481 Insecticide resistance alleles in wetland and residential populations of the West Nile virus vector Culex pipiens in New Jersey
Toumi_2016_J.Environ.Sci.Health.B__1 Effect of carbaryl (carbamate insecticide) on acetylcholinesterase activity of two strains of Daphnia magna (Crustacea, Cladocera)
Huber_2016_J.Biomed.Sci_23_83 Using the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosis
Sharifkhodaei_2016_J.Cell.Sci_129_1477 The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184
Becker_2016_PLoS.Genet_12_e1005961 Cell-Autonomous and Non-cell-autonomous Function of Hox Genes Specify Segmental Neuroblast Identity in the Gnathal Region of the Embryonic CNS in Drosophila
Shepherd_2016_J.Comp.Neurol_524_2677 Postembryonic lineages of the Drosophila ventral nervous system: Neuroglian expression reveals the adult hemilineage associated fiber tracts in the adult thoracic neuromeres
Miller_2016_J.Biol.Chem_291_22559 Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture
Choi_2016_FEMS.Microbiol.Lett_363_ Increased expression of genes involved in uptake and degradation of murein tripeptide under nitrogen starvation in Escherichia coli
Farberg_2016_Biochem.Biophys.Rep_7_415 The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis
Jallouli_2016_Int.J.Biol.Macromol_94_61 Efficient heterologous expression of Fusarium solani lipase, FSL2, in Pichia pastoris, functional characterization of the recombinant enzyme and molecular modeling
Hu_2016_Polym.Degrad.Stab_134_211 Enzymatic degradation of poly(butylene succinate) by cutinase cloned from Fusarium solani
Hikage_2016_Mol.Genet.Genomics_291_989 Allelic variants of the esterase gene W14\/15 differentially regulate overwinter survival in perennial gentian (Gentiana L.)
Gudiukaite_2016_Appl.Biochem.Biotechnol_178_654 Detection of Asp371, Phe375, and Tyr376 Influence on GD-95-10 Lipase Using Alanine Scanning Mutagenesis
Wahab_2016_Enzyme.Microb.Technol_93-94_174 Facile modulation of enantioselectivity of thermophilic Geobacillus zalihae lipase by regulating hydrophobicity of its Q114 oxyanion
Shi_2016_Biochemistry_55_6705 An Atypical alpha\/beta-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae
Li_2016_Int.J.Mol.Sci_17_ Bacterial Expression and Kinetic Analysis of Carboxylesterase 001D from Helicoverpa armigera
Miller_2016_Science_352_555 Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone
Obinata_2016_Eur.J.Cancer_57_39 Abhydrolase domain containing 2, an androgen target gene, promotes prostate cancer cell proliferation and migration
Manda_2016_Biosci.Rep_36_ Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase
Zhao_2016_Cell.Rep_14_2872 alpha\/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes
Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 alpha\/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
Fisette_2016_Cell.Rep_17_1217 alpha\/beta-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility
Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha\/beta-hydrolase domain containing 11 (ABHD11)
Yang_2016_Tumour.Biol_37_1183 Using gastric juice lncRNA-ABHD11-AS1 as a novel type of biomarker in the screening of gastric cancer
Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
Goldenzweig_2016_Mol.Cell_63_337 Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
Macek Hrvat_2016_Chem.Biol.Interact_259_148 HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants
Kosak_2016_Sci.Rep_6_39495 Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Dighe_2016_J.Med.Chem_59_7683 Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening
Kolar_2016_Biochemistry_55_4636 Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
Xiao_2016_J.Biol.Chem_291_23224 A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis
Shi_2016_Biochem.Pharmacol_119_76 Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender
Shi_2016_Basic.Clin.Pharmacol.Toxicol_119_555 Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms
Wang_2016_Pharmacogenomics.J_16_220 CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors
Nzabonimpa_2016_Drug.Metab.Pers.Ther__ Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches
Shang_2016_Xenobiotica_46_393 Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells
Hines_2016_Drug.Metab.Dispos_44_959 Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
Ohura_2016_Drug.Metab.Dispos_44_1890 Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
Fu_2016_Drug.Metab.Dispos_44_1313 Biotransformation Capacity of Carboxylesterase in Skin and Keratinocytes for the Penta-Ethyl Ester Prodrug of DTPA
Xu_2016_Sci.Rep_6_24277 Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4alpha and Protects Against Alcohol- and MCD diet-induced Liver Injury
Zhu_2016_Eur.J.Clin.Pharmacol_72_681 CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril
Zhao_2016_Eur.J.Clin.Pharmacol_72_1195 Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis
Singh_2016_Biosci.Rep_36_ A novel live cell assay to measure diacylglycerol lipase alpha activity
Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Singh_2016_Biochemistry_55_2713 Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta
Li_2016_J.Med.Chem_59_6772 Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes
Wu_2016_ACS.Med.Chem.Lett_7_498 Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes
van Doremalen_2016_J.Virol_90_5499 Mapping the Specific Amino Acid Residues That Make Hamster DPP4 Functional as a Receptor for Middle East Respiratory Syndrome Coronavirus
Wilson_2016_Biol.Chem_397_837 Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches
Li_2016_Drug.Metab.Dispos_44_1341 Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane
Manickam_2016_Eur.J.Med.Chem_117_113 Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase
Shih_2016_Mol.Psychiatry_21_537 Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa
Hanif_2016_Am.J.Physiol.Regul.Integr.Comp.Physiol_311_R676 Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARgamma
Xue_2016_ChemMedChem_11_497 Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration
Chiba_2016_J.Biol.Chem_291_14540 The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: implication of an epoxide hydrolase in the transformation of linoleate
Yokoi_2016_J.Neurosci_36_6431 Identification of PSD-95 Depalmitoylating Enzymes
Gunawardane_2016_J.Biol.Chem_291_2799 Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
Grumet_2016_J.Biol.Chem_291_17977 Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
Gokce_2016_J.Pediatr.Gastroenterol.Nutr_63_e39 The Key Clinical Manifestations of Lysosomal Acid Lipase Deficiency
Kong_2016_Oncol.Rep_36_1852 Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer
Slebe_2016_Nat.Commun_7_11199 FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
Mysling_2016_Elife_5_e20958 The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
Ahn_2016_ACS.Chem.Biol_11_2529 Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism
Anunciado-Koza_2016_Biochimie_124_134 Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet
El Asmar_2016_J.Biol.Chem_291_5116 Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation
Cheung_2016_J.Invest.Dermatol_136_640 Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue
Ross_2016_Arch.Biochem.Biophys_590_72 Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics
Yang_2016_Cell_164_805 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
Gong_2016_Oncotarget_7_68688 Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression
Madan_2016_Oncotarget_7_12386 NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition
Tarver_2016_Bioorg.Med.Chem.Lett_26_1525 Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase
Chen_2016_J.Med.Chem_59_2674 Discovery of Potent and Orally Active Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors as a Potential Therapy for Diabetic Macular Edema
Cahyaningtias_2016_Genes.Dis_3_289 Val279Phe variant of Lp-PLA2 is a risk factor for a subpopulation of Indonesia patients with acute myocardial infarction
Benderly_2016_Biomarkers__1 Lipoprotein-associated phospholipase A, and subsequent cardiovascular events and mortality among patients with coronary heart disease
Woolford_2016_J.Med.Chem_59_10738 Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
Liu_2016_J.Med.Chem_59_5115 Structural and Thermodynamic Characterization of Protein-Ligand Interactions Formed between Lipoprotein-Associated Phospholipase A2 and Inhibitors
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Grothusen_2016_Genome.Announc_4_e01756 First Complete Genome Sequence of Tenacibaculum dicentrarchi, an Emerging Bacterial Pathogen of Salmonids
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Nomura_2016_Chem.Biol.Interact_259_211 Lipases and their inhibitors in health and disease
Joosen_2016_Chem.Biol.Interact_259_115 Increasing nerve agent treatment efficacy by P-glycoprotein inhibition
Kratky_2016_Molecules_21_ Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates
Liu_2016_J.Zhejiang.Univ.Sci.B_17_110 Developing antibodies from cholinesterase derived from prokaryotic expression and testing their feasibility for detecting immunogen content in Daphnia magna
Mantoani_2016_Molecules_21_ Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors
Mathpati_2016_Enzyme.Microb.Technol_84_1 Kinetic modeling and docking study of immobilized lipase catalyzed synthesis of furfuryl acetate
Muhammad_2016_Pharm.Biol__1 Phytochemicals from Dodonaea viscosa and their antioxidant and anticholinesterase activities with structure-activity relationships
Pasanisi_2016_Int.J.Cardiol_207_165 Severe cardiomyopathy in a young patient with complete deficiency of adipose triglyceride lipase due to a novel mutation in PNPLA2 gene
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Prabsattroo_2016_Oxid.Med.Cell.Longev_2016_5789857 Positive Modulation of Pink Nelumbo nucifera Flowers on Memory Impairment, Brain Damage, and Biochemical Profiles in Restraint Rats
Prokic_2016_Ecotoxicol.Environ.Saf_128_21 Antioxidative responses of the tissues of two wild populations of Pelophylax kl. esculentus frogs to heavy metal pollution
Reutgard_2016_Aquat.Toxicol_173_36 Linking sub-cellular biomarkers to embryo aberrations in the benthic amphipod Monoporeia affinis
Schulze_2016_Curr.Protoc.Immunol_112_22F 6 1 Culture, Expansion, and Differentiation of Murine Megakaryocytes from Fetal Liver, Bone Marrow, and Spleen
Tian_2016_Enzyme.Microb.Technol_84_32 First Novozym 435 lipase-catalyzed Morita-Baylis-Hillman reaction in the presence of amides
Wang_2016_Rapid.Commun.Mass.Spectrom_30_553 Targeted absolute quantitative proteomics with SILAC internal standards and unlabeled full-length protein calibrators (TAQSI)
Wang_2016_Pestic.Biochem.Physiol_127_1 Conifer flavonoid compounds inhibit detoxification enzymes and synergize insecticides
Yang_2016_Cell.Physiol.Biochem_38_696 Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARx03B3\; Signaling
Zheng_2016_Sci.Rep_6_21593 Characterization of DWARF14 Genes in Populus
Alghazwi_2016_Curr.Med.Chem_23_360 Neuroprotective Activities of Marine Natural Products from Marine Sponges
Alout_2016_Heredity.(Edinb)_116_224 High chlorpyrifos resistance in Culex pipiens mosquitoes: strong synergy between resistance genes
Alter_2016_Can.J.Cardiol_32_217 From Heart Failure to Highly Unsaturated Fatty Acid Deficiency and Vice Versa: Bidirectional Heart and Liver Interactions
Badgujar_2016_Bioprocess.Biosyst.Eng_39_211 Enhanced biocatalytic activity of immobilized Pseudomonas cepacia lipase under sonicated condition
Badin_2016_Neuropharmacol_105_47 (II) Physiological profiling of an endogenous peptide in the basal forebrain: Age-related bioactivity and blockade with a novel modulator
Bancerz_2016_Biotechnol.Appl.Biochem_63_67 New alkaline lipase from Rhizomucor variabilis: Biochemical properties and stability in the presence of microbial EPS
Blocher_2016_J.Med.Chem_59_61 N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase\/Peroxisome Proliferator-Activated Receptor gamma Modulators
Blotnick-Rubin_2016_Neurosci_319_221 Exercise modulates synaptic acetylcholinesterase at neuromuscular junctions
Buczynski_2016_Proc.Natl.Acad.Sci.U.S.A_113_1086 Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure
Carelli-Alinovi_2016_Biochimie_121_52 Involvement of acetylcholinesterase and protein kinase C in the protective effect of caffeine against beta-amyloid-induced alterations in red blood cells
Chalghmi_2016_Arch.Environ.Contam.Toxicol_70_241 Transcriptomic, Biochemical, and Histopathological Responses of the Clam Ruditapes decussatus from a Metal-Contaminated Tunis Lagoon
Chanda_2016_Mol.Psychiatry_21_169 Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking
Chiu_2016_Arterioscler.Thromb.Vasc.Biol_36_145 Cardiomyocyte VEGF Regulates Endothelial Cell GPIHBP1 to Relocate Lipoprotein Lipase to the Coronary Lumen During Diabetes Mellitus
Chlebek_2016_Fitoterapia_109_241 Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets
Chou_2016_Parkinsonism.Relat.Disord_23_45 Neuroimaging and clinical predictors of fatigue in Parkinson disease
Coetzee_2016_J.Ethnopharmacol_177_111 High-mesembrine Sceletium extract (Trimesemine) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor
Connelly_2016_J.Diabetes_8_63 Dipeptidyl peptidase-4 inhibition improves cardiac function in experimental myocardial infarction: Role of stromal cell-derived factor-1alpha
Cooper_2016_Age.Ageing_45_148 Observational cohort study: deprivation and access to anti-dementia drugs in the UK
Cross_2016_Drugs.Aging_33_37 Potentially Inappropriate Medications and Anticholinergic Burden in Older People Attending Memory Clinics in Australia
Cummings_2016_CNS.Neurosci.Ther_22_159 Role of Donepezil in the Management of Neuropsychiatric Symptoms in Alzheimer's Disease and Dementia with Lewy Bodies
Cwiklinska_2016_Chem.Phys.Lipids_195_63 Impact of phosphatidylcholine liposomes on the compositional changes of VLDL during lipoprotein lipase (LPL)-mediated lipolysis
de Hoyos-Alonso_2016_Neurologia_31_1 Estimated prevalence of dementia based on analysis of drug databases in the Region of Madrid (Spain)
Devamani_2016_J.Am.Chem.Soc_138_1046 Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases
Dewer_2016_Environ.Sci.Pollut.Res.Int_23_3086 Behavioral and metabolic effects of sublethal doses of two insecticides, chlorpyrifos and methomyl, in the Egyptian cotton leafworm, Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae)
Dolejsi_2016_J.Neurochem_136_503 Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice
Dos_2016_Arch.Toxicol_90_647 Long-term and low-dose malathion exposure causes cognitive impairment in adult mice: evidence of hippocampal mitochondrial dysfunction, astrogliosis and apoptotic events
Durieux_2016_J.Neurophysiol_115_5 Neuroligin-2 and the tightrope of excitation\/inhibition balance in the prefrontal cortex
Eimar_2016_Bone_84_131 Donepezil regulates energy metabolism and favors bone mass accrual
Fang_2016_Bioorg.Med.Chem_24_886 Ferulic acid-carbazole hybrid compounds: Combination of cholinesterase inhibition, antioxidant and neuroprotection as multifunctional anti-Alzheimer agents
Fang_2016_Mol.Neurobiol_53_270 Neuroligin-1 Knockdown Suppresses Seizure Activity by Regulating Neuronal Hyperexcitability
Fedoce_2016_Psychopharmacology.(Berl)_233_267 M3 muscarinic receptor in the ventral medial prefrontal cortex modulating the expression of contextual fear conditioning in rats
Fukuoka_2016_Appl.Microbiol.Biotechnol_100_1733 Control of enzymatic degradation of biodegradable polymers by treatment with biosurfactants, mannosylerythritol lipids, derived from Pseudozyma spp. yeast strains
Gao_2016_J.Pharmacol.Exp.Ther_356_645 Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons
Garcia-Garcia_2016_Life.Sci_145_274 Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level
Gauthier_2016_Aquat.Toxicol_170_377 Behavioural alterations from exposure to Cu, phenanthrene, and Cu-phenanthrene mixtures: linking behaviour to acute toxic mechanisms in the aquatic amphipod, Hyalella azteca
Gong_2016_Exp.Gerontol_74_21 Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by d-galactose
Goomber_2016_Gene_576_237 Disruption of N terminus long range non covalent interactions shifted temp.opt 25 degrees C to cold: Evolution of point mutant Bacillus lipase by error prone PCR
Grabner_2016_J.Biol.Chem_291_913 Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation
Haslam_2016_J.Biomol.Screen_21_176 The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond
Hategan_2016_Gen.Hosp.Psychiatry_38_115 e1 Donepezil-associated manic episode with psychotic features: a case report and review of the literature
Hegazy_2016_Hum.Exp.Toxicol_35_251 Comparative study of cholinergic and oxidative stress biomarkers in brains of diabetic and hypercholesterolemic rats
Hegazy_2016_Planta.Med_82_138 Sesquiterpene Lactones from Cynara cornigera: Acetyl Cholinesterase Inhibition and In Silico Ligand Docking
Henderson_2016_Lancet.Neurol_15_249 Rivastigmine for gait stability in patients with Parkinson's disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial
Herrmann_2016_J.Am.Med.Dir.Assoc_17_142 A Randomized Placebo-Controlled Discontinuation Study of Cholinesterase Inhibitors in Institutionalized Patients With Moderate to Severe Alzheimer Disease
Higashino_2016_Psychopharmacology.(Berl)_233_521 Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice
Horsman_2016_Nat.Prod.Rep_33_183 Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?
Huang_2016_Gene_580_73 Identification of biotransformation enzymes in the antennae of codling moth Cydia pomonella
Ibarria_2016_J.Alzheimers.Dis_50_559 Beneficial Effects of an Integrated Psychostimulation Program in Patients with Alzheimer's Disease
Inoue_2016_Neuropharmacol_105_318 Nicotinic acetylcholine receptor-mediated GABAergic inputs to cholinergic interneurons in the striosomes and the matrix compartments of the mouse striatum
Iqbal_2016_Med.Chem_12_74 Biological Evaluation of Azomethine-dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors
Jameel_2016_Chem.Biol.Drug.Des_87_21 Coumarin: A Privileged Scaffold for the Design and Development of Antineurodegenerative Agents
Jeon_2016_Environ.Sci.Pollut.Res.Int_23_1071 Chlorpyrifos-induced biomarkers in Japanese medaka (Oryzias latipes)
Ji_2016_Curr.Opin.Psychiatry_29_103 Pharmacotherapy for mental health problems in people with intellectual disability
Judge_2016_Chem.Biol.Interact_245_82 Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system
Julve_2016_Clin.Chim.Acta_455_134 Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics
Kameshima_2016_Acta.Physiol.(Oxf)_216_203 Visceral adipose tissue-derived serine protease inhibitor augments acetylcholine-induced relaxation via the inhibition of acetylcholine esterase activity in rat isolated mesenteric artery
Karasova_2016_Neurotox.Res_29_267 Small Quaternary Inhibitors K298 and K524: Cholinesterases Inhibition, Absorption, Brain Distribution, and Toxicity
Kazui_2016_Drug.Metab.Dispos_44_115 Human Intestinal Raf Kinase Inhibitor Protein (RKIP) Catalyzes Prasugrel as a Bioactivation Hydrolase
Keri_2016_Chem.Biol.Drug.Des_87_101 New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease
Keyzer-Dekker_2016_Eur.J.Pediatr.Surg_26_100 Effectiveness of Rectal Suction Biopsy in Diagnosing Hirschsprung Disease
Khosrowbeygi_2016_Endocrine_51_245 Maternal circulating levels of some metabolic syndrome biomarkers in gestational diabetes mellitus
Kinoshita_2016_J.Lipid.Res_57_4 Glycosylphosphatidylinositol (GPI) Anchors: Biochemistry and Cell Biology: Introduction to a Thematic Review Series
Kinoshita_2016_J.Lipid.Res_57_6 Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling
Konigsbrugge_2016_Oncologist_21_252 Association Between Decreased Serum Albumin With Risk of Venous Thromboembolism and Mortality in Cancer Patients
Kovacic_2016_Protein.Eng.Des.Sel_29_65 Structural features determining thermal adaptation of esterases
Krueger_2016_J.Physiol_594_357 Neural influences on human intestinal epithelium in vitro
Kumar_2016_Brain_139_174 Amyloid-beta peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAbetaACs
Kuzma_2016_Phytother.Res_30_234 Taxodione and Extracts from Salvia austriaca Roots as Human Cholinesterase Inhibitors
Lai_2016_J.Comp.Neurol_524_807 Developmental expression of the neuroligins and neurexins in fragile X mice
Larsson_2016_Cell.Signal_28_204 Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase
Lawrence_2016_J.Cancer.Surviv_10_176 A study of donepezil in female breast cancer survivors with self-reported cognitive dysfunction 1 to 5 years following adjuvant chemotherapy
Lee_2016_J.Clin.Neurol_12_57 Treatment of Alzheimer's Disease with Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Lee_2016_Toxicology_340_53 Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides
Leomanni_2016_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_183-184_20 Mercury induced haemocyte alterations in the terrestrial snail Cantareus apertus as novel biomarker
Li_2016_Int.J.Biol.Macromol_86_119 Ionic liquids as novel solvents for biosynthesis of octenyl succinic anhydride-modified waxy maize starch
Li_2016_Environ.Toxicol_31_278 Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin
Liu_2016_CNS.Neurosci.Ther_22_220 ST09, a Novel Thioester Derivative of Tacrine, Alleviates Cognitive Deficits and Enhances Glucose Metabolism in Vascular Dementia Rats
Loureiro_2016_Mol.Neurobiol_53_1065 Crosstalk Among Disrupted Glutamatergic and Cholinergic Homeostasis and Inflammatory Response in Mechanisms Elicited by Proline in Astrocytes
Luo_2016_Bioorg.Med.Chem_24_672 Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities
Luo_2016_J.Ethnopharmacol_178_66 A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases
Lv_2016_Mol.Genet.Genomics_291_309 Comparative transcriptome analyses of deltamethrin-susceptible and -resistant Culex pipiens pallens by RNA-seq
Makhaeva_2016_Bioorg.Med.Chem_24_1050 Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors
Matusica_2016_J.Cell.Sci_129_517 Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment
Mertens_2016_Toxicol.Lett_244_161 A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity
Misik_2016_Neurosci.Lett_612_261 Effects of novel tacrine-related cholinesterase inhibitors in the reversal of 3-quinuclidinyl benzilate-induced cognitive deficit in rats-Is there a potential for Alzheimer's disease treatment?
Miyazawa_2016_J.Nat.Med_70_282 Chemical composition, aroma evaluation, and inhibitory activity towards acetylcholinesterase of essential oils from Gynura bicolor DC
Mizoi_2016_Bioorg.Med.Chem.Lett_26_921 Synthesis and evaluation of atorvastatin esters as prodrugs metabolically activated by human carboxylesterases
Moreau_2016_Lancet.Neurol_15_232 Acetylcholinesterase inhibitors and gait: a steadying hand?
Murthy_2016_J.Pharmacol.Exp.Ther_356_720 Cocaine Hydrolase Gene Transfer Demonstrates Cardiac Safety and Efficacy against Cocaine-Induced QT Prolongation in Mice
Nasr_2016_Environ.Sci.Pollut.Res.Int_23_1852 Neuro and renal toxicity induced by chlorpyrifos and abamectin in rats : Toxicity of insecticide mixture
Nesakumar_2016_Bull.Environ.Contam.Toxicol_96_217 Evaluation of Inhibition Efficiency for the Detection of Captan, 2,3,7,8-Tetrachlorodibenzodioxin, Pentachlorophenol and Carbosulfan in Water: An Electrochemical Approach
Newman_2016_Psychopharmacology.(Berl)_233_925 Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist
Noremberg_2016_Biol.Trace.Elem.Res_169_77 Silicon Reverses Lipid Peroxidation but not Acetylcholinesterase Activity Induced by Long-Term Exposure to Low Aluminum Levels in Rat Brain Regions
Olsen_2016_Org.Biomol.Chem_14_1629 Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs
Ouyang_2016_Poult.Sci_95_99 Effects of abhydrolase domain containing 5 gene (ABHD5) expression and variations on chicken fat metabolism
Ouyang_2016_Anal.Chem_88_2353 Rapid Screening of Acetylcholinesterase Inhibitors by Effect-Directed Analysis Using LC x LC Fractionation, a High Throughput in Vitro Assay, and Parallel Identification by Time of Flight Mass Spectrometry
Paiva_2016_Genomics_107_40 Identification of a major Quantitative Trait Locus determining resistance to the organophosphate temephos in the dengue vector mosquito Aedes aegypti
Pakravan_2016_Hum.Exp.Toxicol_35_297 Measurement of cholinesterase enzyme activity before and after exposure to organophosphate pesticides in farmers of a suburb region of Mazandaran, a northern province of Iran
Pan_2016_Wiley.Interdiscip.Rev.Nanomed.Nanobiotechnol_8_85 Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery
Passlick_2016_Cereb.Cortex_26_51 The NG2 Protein Is Not Required for Glutamatergic Neuron-NG2 Cell Synaptic Signaling
Patricio-Martinez_2016_Neurosci_315_18 The recombinant C-terminal fragment of tetanus toxin protects against cholinotoxicity by intraseptal injection of beta-amyloid peptide (25-35) in rats
Pauziene_2016_J.Anat_228_26 Innervation of the rabbit cardiac ventricles
Payolla_2016_Mol.Cell.Endocrinol_422_192 High-fat diet during pregnancy and lactation impairs the cholinergic anti-inflammatory pathway in the liver and white adipose tissue of mouse offspring
Peng_2016_Chem.Biol.Interact_243_82 Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma
Phillips_2016_Environ.Health.Perspect_124_53 A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways
Rao_2016_Neurotoxicol_52_230 Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism
Renick_2016_Aquat.Toxicol_170_335 Effects of a pesticide and a parasite on neurological, endocrine, and behavioral responses of an estuarine fish
Rios_2016_Exp.Brain.Res_234_605 Dopamine-dependent modulation of rat globus pallidus excitation by nicotine acetylcholine receptors
Salaga_2016_J.Pharmacol.Exp.Ther_356_157 Encenicline, an alpha7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice
Sanchez-Santed_2016_Cortex_74_417 Organophosphate pesticide exposure and neurodegeneration
Santos_2016_Environ.Sci.Pollut.Res.Int_23_266 Brain cholinesterase reactivation as a marker of exposure to anticholinesterase pesticides: a case study in a population of yellow-legged gull Larus michahellis (Naumann, 1840) along the northern coast of Portugal
Sayin_2016_Auton.Neurosci_194_26 Assessment of cardiac autonomic tone in conscious rats
Schama_2016_Insect.Biochem.Mol.Biol_69_91 Rhodnius prolixus supergene families of enzymes potentially associated with insecticide resistance
Segrec_2016_Psychogeriatrics_16_70 Increased libido associated with donepezil treatment: a case report
Selim_2016_Prep.Biochem.Biotechnol_46_131 High expression level of antioxidants and pharmaceutical bioactivities of endophytic fungus Chaetomium globosum JN711454
Shah_2016_Mov.Disord_31_111 Striatal and Cortical beta-Amyloidopathy and Cognition in Parkinson's Disease
Shaikh_2016_Biotechnol.Appl.Biochem_63_145 Forxiga (dapagliflozin): Plausible role in the treatment of diabetes-associated neurological disorders
Singh_2016_Curr.Neurovasc.Res_13_10 Reversal in Cognition Impairments, Cholinergic Dysfunction, and Cerebral Oxidative Stress Through the Modulation of Ryanodine Receptors (RyRs) and Cysteinyl Leukotriene-1 (CysLT1) Receptors
Small_2016_Neurosci.Lett_616_80 Ventral tegmental area muscarinic receptors modulate depression and anxiety-related behaviors in rats
Spicakova_2016_Food.Chem.Toxicol_88_100 Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators
Stanton_2016_Pract.Neurol_16_42 Apathy: a practical guide for neurologists
Sternberg_2016_Autoimmun.Rev_15_113 Promoting sympathovagal balance in multiple sclerosis\; pharmacological, non-pharmacological, and surgical strategies
Story_2016_Environ.Toxicol.Chem_35_152 Fenitrothion, an organophosphorous insecticide, impairs locomotory function and alters body temperatures in Sminthopsis macroura (Gould 1845) without reducing metabolic rates during running endurance and thermogenic performance tests
Sun_2016_Bioorg.Med.Chem.Lett_26_747 Design and discovery of Novel Thiazole acetamide derivatives as anticholinesterase agent for possible role in the management of Alzheimer's
Syed_2016_Chem.Biol.Interact_243_19 Beta-cyfluthrin induced neurobehavioral impairments in adult rats
Tamasaki_2016_Brain.Dev_38_113 Effects of donepezil and serotonin reuptake inhibitor on acute regression during adolescence in Down syndrome
Terwege_2016_ChemMedChem_11_429 omega-Imidazolyl- and omega-Tetrazolylalkylcarbamates as Inhibitors of Fatty Acid Amide Hydrolase: Biological Activity and in vitro Metabolic Stability
Tomaz_2016_Exp.Biol.Med.(Maywood)_241_40 Light therapy modulates serotonin levels and blood flow in women with headache. A preliminary study
Tonin_2016_Comp.Immunol.Microbiol.Infect.Dis_44_61 Novel markers of inflammatory response and hepatic dysfunction in canine leishmaniasis
Trac_2016_Environ.Toxicol.Chem_35_394 Deciphering mechanisms of malathion toxicity under pulse exposure of the freshwater cladoceran Daphnia magna
Tsoi_2016_J.Am.Med.Dir.Assoc_17_24 Time to Treatment Initiation in People With Alzheimer Disease: A Meta-Analysis of Randomized Controlled Trials
Tyukhtenko_2016_J.Biol.Chem_291_2556 Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES
Ujiie_2016_J.Biosci.Bioeng_121_303 Extracellular production of Pseudozyma (Candida) antarctica lipase B with genuine primary sequence in recombinant Escherichia coli
Ulbrich_2016_Biochem.J_473_423 Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system
Valenzuela-Munoz_2016_Mar.Genomics_25_103 Transcriptome mining: Multigene panel to test delousing drug response in the sea louse Caligus rogercresseyi
Vaquero_2016_Appl.Microbiol.Biotechnol_100_2047 Properties, structure, and applications of microbial sterol esterases
Vernekar_2016_Angew.Chem.Int.Ed.Engl_55_1412 Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the Degradation of Nerve Agents
Vijayaraghavan_2016_J.Alzheimers.Dis_50_567 Association of Butyrylcholinesterase-K Allele and Apolipoprotein E varepsilon4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease
von der Wellen_2016_Toxicol.Lett_244_124 Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro
Vrancheva_2016_Z.Naturforsch.C_71_9 Alkaloid profiles and acetylcholinesterase inhibitory activities of Fumaria species from Bulgaria
Wang_2016_Chem.Commun.(Camb)_52_3183 A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples
Wang_2016_Toxicol.Sci_149_145 Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury
Wang_2016_Arch.Toxicol_90_81 Fumonisins: oxidative stress-mediated toxicity and metabolism in vivo and in vitro
Winter_2016_Toxicol.Lett_244_136 Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
Yamano_2016_J.Crit.Care_31_36 Low total cholesterol and high total bilirubin are associated with prognosis in patients with prolonged sepsis
Yuan_2016_Environ.Pollut_208_670 Targeting neurotrophic factors and their receptors, but not cholinesterase or neurotransmitter, in the neurotoxicity of TDCPP in Chinese rare minnow adults (Gobiocypris rarus)
Zhang_2016_Psychopharmacology.(Berl)_233_599 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Abeta25-35-impaired mouse cognitive function
Barka_2016_Biochim.Biophys.Acta_1861_239 Identification of a triacylglycerol lipase in the diatom Phaeodactylum tricornutum
Caussy_2016_Atherosclerosis_246_280 Multiple microRNA regulation of lipoprotein lipase gene abolished by 3'UTR polymorphisms in a triglyceride-lowering haplotype harboring p.Ser474Ter
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Li_2016_Chin.Med.J.(Engl)_129_405 Chromosomal and Genetic Analysis of a Human Lung Adenocarcinoma Cell Line OM
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Newell-Litwa_2016_J.Cell.Biol_212_375 Breaking down to build up: Neuroligin's C-terminal domain strengthens the synapse
Saffari_2016_Transl.Psychiatry_6_e736 NPY(+)-, but not PV(+)-GABAergic neurons mediated long-range inhibition from infra- to prelimbic cortex
Umehara_2016_Xenobiotica__1 Esterase phenotyping in human liver in vitro: specificity of carboxylesterase inhibitors
Wattmo_2016_Alzheimers.Res.Ther_8_7 Mild versus moderate stages of Alzheimer's disease: three-year outcomes in a routine clinical setting of cholinesterase inhibitor therapy
Adedara_2016_Environ.Toxicol.Pharmacol_42_243 Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea
Ali_2016_Asian.Pac.J.Trop.Med_9_103 Anti-Alzheimer's disease potential of coumarins from Angelica decursiva and Artemisia capillaris and structure-activity analysis
Brawner_2016_Chem.Biol.Interact_249_19 Heat pretreatment eliminates spurious butyrylcholinesterase enhancement of endotoxin levels in the kinetic chromogenic assay
Brimijoin_2016_Chem.Biol.Interact_259_271 Physiological Roles for Butyrylcholinesterase: A BChE-Ghrelin Axis
Chen_2016_Eur.Neurol_75_132 Efficacy of Cholinesterase Inhibitors in Vascular Dementia: An Updated Meta-Analysis
Dahan-Moss_2016_Parasit.Vectors_9_110 Analysis of esterase enzyme activity in adults of the major malaria vector Anopheles funestus
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Garcia-Jacas_2016_J.Cheminform_8_10 Examining the predictive accuracy of the novel 3D N-linear algebraic molecular codifications on benchmark datasets
Hou_2016_Food.Chem_202_81 A sensitive fluorescent sensor for selective determination of dichlorvos based on the recovered fluorescence of carbon dots-Cu(II) system
Islam_2016_Chem.Biol.Interact_249_1 Human serum albumin reduces the potency of acetylcholinesterase inhibitor based drugs for Alzheimer's disease
Masson_2016_Chem.Biol.Interact_259_319 Emergence of catalytic bioscavengers against organophosphorus agents
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Bedi_2016_Infect.Immun_84_1975 Enhanced Clearance of Pseudomonas aeruginosa by Peroxisome Proliferator-Activated Receptor Gamma
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Buendia_2016_Mol.Neurobiol_53_3338 Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
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Choi_2016_BMB.Rep_49_349 Identification of amino acids related to catalytic function of Sulfolobus solfataricus P1 carboxylesterase by site-directed mutagenesis and molecular modeling
Chou_2016_Biotechnol.Appl.Biochem_63_371 A novel recombinant chlorophyllase from cyanobacterium Cyanothece sp. ATCC 51142 for the production of bacteriochlorophyllide a
Clarelli_2016_J.Alzheimers.Dis_52_1203 CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients
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Dgachi_2016_ChemMedChem_11_1318 Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy
Dolles_2016_ChemMedChem_11_1270 Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders
Dorywalska_2016_Mol.Cancer.Ther_15_958 Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design
Eckart_2016_Neuroimage_137_61 Acetylcholine modulates human working memory and subsequent familiarity based recognition via alpha oscillations
Elistratova_2016_Analyst_141_4204 Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6](4.)
Fisar_2016_Prog.Neuropsychopharmacol.Biol.Psychiatry_69_112 Drugs related to monoamine oxidase activity
Flematti_2016_Planta_243_1361 Stereospecificity in strigolactone biosynthesis and perception
Fu_2016_J.Pharm.Sci_105_989 Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases
Fuenzalida_2016_Curr.Pharm.Des_22_2004 Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases
Gawel_2016_J.Psychopharmacol_30_676 Acquisition and reinstatement of ethanol-induced conditioned place preference in rats: Effects of the cholinesterase inhibitors donepezil and rivastigmine
Gibbons_2016_Curr.Pharm.Des_22_2124 The Cholinergic System: An Emerging Drug Target for Schizophrenia
Go_2016_Nutr.Neurosci_19_247 Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice
Grasing_2016_Behav.Brain.Res_312_148 A threshold model for opposing actions of acetylcholine on reward behavior: Molecular mechanisms and implications for treatment of substance abuse disorders
Groselj_2016_Mol.Divers_20_667 Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides
Guler_2016_Environ.Sci.Pollut.Res.Int_23_12343 Electrochemical detection of malathion pesticide using acetylcholinesterase biosensor based on glassy carbon electrode modified with conducting polymer film
Haider_2016_Brain.Res_1644_141 beta-glucan attenuated scopolamine induced cognitive impairment via hippocampal acetylcholinesterase inhibition in rats
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Heier_2016_J.Biol.Chem_291_11865 Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
Hiramoto_2016_Photodermatol.Photoimmunol.Photomed_32_129 Long-term UVA eye irradiation causes decreased learning ability in mice
Holleran_2016_Neuropsychopharmacology_41_2062 Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking
Ikhlef_2016_FEBS.Lett_590_1614 Paraoxonase 1-treated oxLDL promotes cholesterol efflux from macrophages by stimulating the PPARgamma-LXRalpha-ABCA1 pathway
Imai_2016_J.Pharm.Sci_105_714 Expression of Carboxylesterase Isozymes and Their Role in the Behavior of a Fexofenadine Prodrug in Rat Skin
Jansson_2016_Anal.Chem_88_6195 Monitoring Enzymatic Reactions in Real Time Using Venturi Easy Ambient Sonic-Spray Ionization Mass Spectrometry
Jayant_2016_Brain.Res_1642_397 Protective effect of transient receptor potential vanilloid subtype 1 (TRPV1) modulator, against behavioral, biochemical and structural damage in experimental models of Alzheimer's disease
Justin_2016_Nutr.Neurosci_19_269 Tannoid principles of Emblica officinalis renovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease
Kalkman_2016_Cell.Mol.Life.Sci_73_2511 Modulatory effects of alpha7 nAChRs on the immune system and its relevance for CNS disorders
Kan_2016_Behav.Brain.Res_312_265 Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice
Kang_2016_Biotechnol.Lett_38_1009 Discovery of novel feruloyl esterase activity of BioH in Escherichia coli BL21(DE3)
Kang_2016_ACS.Nano_10_5346 Optical Detection of Enzymatic Activity and Inhibitors on Non-Covalently Functionalized Fluorescent Graphene Oxide
Kaur_2016_Regul.Toxicol.Pharmacol_80_82 Low dose X-irradiation mitigates diazepam induced depression in rat brain
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Kim_2016_Behav.Brain.Res_312_39 Anti-amnesic effect of Dendropanax morbifera via JNK signaling pathway on cognitive dysfunction in high-fat diet-induced diabetic mice
Kim_2016_Pain_157_1314 Neuroligin 2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain
Kim_2016_J.Ethnopharmacol_188_123 Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant\/antiapoptotic pathway
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Kumar_2016_Bioresour.Technol_213_64 Modulation of fatty acid metabolism and tricarboxylic acid cycle to enhance the lipstatin production through medium engineering in Streptomyces toxytricini
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Le Guernic_2016_Ecotoxicology_25_1234 In situ effects of metal contamination from former uranium mining sites on the health of the three-spined stickleback (Gasterosteus aculeatus, L.)
Leitemperger_2016_Fish.Physiol.Biochem_42_1005 Early biochemical biomarkers for zinc in silver catfish (Rhamdia quelen) after acute exposure
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Liu_2016_Mol.Genet.Genomics_291_1105 Genome-wide identification, classification and expression analysis in fungal-plant interactions of cutinase gene family and functional analysis of a putative ClCUT7 in Curvularia lunata
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Khan_2016_J.Biomol.Struct.Dyn__1 Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens
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Koh_2016_Lab.Anim.Res_32_105 Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Abeta-42 accumulation and neurotoxicant injection
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Vazzana_2016_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_201_61 Are mussels able to distinguish underwater sounds? Assessment of the reactions of Mytilus galloprovincialis after exposure to lab-generated acoustic signals
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Pastryk_2016_Chem.Biol.Interact_259_407 Effects of antiretroviral treatment on paraoxonase 1 (PON1) activity in rats
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Bellinato_2016_Biomed.Res.Int_2016_8603263 Resistance Status to the Insecticides Temephos, Deltamethrin, and Diflubenzuron in Brazilian Aedes aegypti Populations
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Ghisi_2016_Chemosphere_161_69 Integrated biomarker response in catfish Hypostomus ancistroides by multivariate analysis in the Pirapo River, southern Brazil
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Arikawa_2016_Eur.J.Pharmacol_789_17 Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation
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Chang_2016_Drugs_76_1093 Psychosis in Parkinson's Disease: Epidemiology, Pathophysiology, and Management
Chiantore_2016_J.Cancer.Res.Clin.Oncol_142_1751 Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis
Choi_2016_J.Ethnopharmacol_190_219 BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides
Colloby_2016_Neurology_87_178 Cholinergic and perfusion brain networks in Parkinson disease dementia
Da Silva_2016_Microb.Pathog_98_93 Hepatic cholinesterase of laying hens naturally infected by Salmonella Gallinarum (fowl typhoid)
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Ghayomi_2016_Hum.Exp.Toxicol_35_839 A mechanistic approach for modulation of chlorpyrifos-induced toxicity in human lymphocytes by melatonin, coenzyme Q10, and vinpocetine
Goncalves_2016_Langmuir_32_6746 Nanoencapsulated Lecitase Ultra and Thermomyces lanuginosus Lipase, a Comparative Structural Study
Grasing_2016_Am.J.Addict_25_392 Cocaine cardiovascular effects and pharmacokinetics after treatment with the acetylcholinesterase inhibitor donepezil
Ibrahim_2016_Mol.Ecol_25_3436 The P450 CYP6Z1 confers carbamate\/pyrethroid cross-resistance in a major African malaria vector beside a novel carbamate-insensitive N485I acetylcholinesterase-1 mutation
Jafari-Sabet_2016_Behav.Pharmacol_27_470 Tramadol state-dependent memory: involvement of dorsal hippocampal muscarinic acetylcholine receptors
Kaur_2016_Inflammopharmacology_24_133 Neurokinin-1 receptor inhibition reverses ischaemic brain injury and dementia in bilateral common carotid artery occluded rats: possible mechanisms
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Kim_2016_J.Agric.Food.Chem_64_5479 Insecticidal and Enzyme Inhibitory Activities of Sparassol and Its Analogues against Drosophila suzukii
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Vilanova_2016_Chem.Biol.Interact_259_49 Editorial
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Amel_2016_J.Food.Sci.Technol_53_1454 Extra virgin olive oil modulates brain docosahexaenoic acid level and oxidative damage caused by 2,4-Dichlorophenoxyacetic acid in rats
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Fisher_2016_Value.Health_19_688 Cholinesterase Inhibitor Utilization: The Impact of Provincial Drug Policy on Discontinuation
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Mocan_2016_J.Enzyme.Inhib.Med.Chem__1 Enzymatic assays and molecular modeling studies of Schisandra chinensis lignans and phenolics from fruit and leaf extracts
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Rabacchi_2016_J.Clin.Lipidol_10_915 Clinical and genetic features of 3 patients with familial chylomicronemia due to mutations in GPIHBP1 gene
Rahman_2016_Springerplus_5_1346 Halogen-directed drug design for Alzheimer's disease: a combined density functional and molecular docking study
Ramsay_2016_Front.Neurosci_10_375 Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
Rathmann_2016_In.Vivo_30_707 Benefit of Patients with an Early and Progressed State of Hepatocellular Carcinoma Treated with Drug-eluting Beads
Sanli_2016_J.Pharm.Biomed.Anal_131_188 Development and validation of a capillary zone electrophoretic method for rapid and sensitive determination of galanthamine: Application in plant and pharmaceuticals
Spieker_2016_PLoS.One_11_e0161675 Acetylcholinesterase Regulates Skeletal In Ovo Development of Chicken Limbs by ACh-Dependent and -Independent Mechanisms
Wattmo_2016_BMC.Neurol_16_156 Cholinesterase inhibitors do not alter the length of stay in nursing homes among patients with Alzheimer's disease: a prospective, observational study of factors affecting survival time from admission to death
Wieckowska_2016_Eur.J.Med.Chem_124_63 Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation
Zappaterra_2016_Meat.Sci_121_27 A gene and protein expression study on four porcine genes related to intramuscular fat deposition
Zhang_2016_J.Neurosci_36_9070 Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons
Zhong_2016_Curr.Opin.Lipidol_27_484 Dipeptidyl peptidase-4 inhibition: insights from the bench and recent clinical studies
Zhou_2016_Lipids.Health.Dis_15_135 Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine
Epstein_2016_Biophys.J_111_333 Bayesian Statistical Inference in Ion-Channel Models with Exact Missed Event Correction
Tiveron_2016_PLoS.One_11_e0157052 LAMP5 Fine-Tunes GABAergic Synaptic Transmission in Defined Circuits of the Mouse Brain
Ztaou_2016_J.Neurosci_36_9161 Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease
Aftabuddin_2016_Mymensingh.Med.J_25_536 Outcome of Extended Thymectomy in Myasthenia Crisis Patient
Altinyazar_2016_Indian.J.Clin.Biochem_31_473 The Red Blood Cell Acetylcholinesterase Levels of Depressive Patients with Suicidal Behavior in an Agricultural Area
Amani_2016_Cell.J_18_464 Chlorpyrifos Toxicity in Mouse Cultured Cerebellar Granule Neurons at Different Stages of Development: Additive Effect on Glutamate-Induced Excitotoxicity
Andrade_2016_Pharmacogn.Mag_12_171 In vitro Antioxidant and Enzymatic Approaches to Evaluate Neuroprotector Potential of Blechnum Extracts without Cytotoxicity to Human Stem Cells
Chen_2016_Med.Sci.Monit_22_3196 Association Between Paraoxonase 2 Ser311Cys Polymorphism and Coronary Heart Disease Risk: A Meta-Analysis
Connor_2016_Neuron_91_1052 Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2
Doherty_2016_Physiol.Biochem.Zool_89_364 Exploring the Bone Proteome to Help Explain Altered Bone Remodeling and Preservation of Bone Architecture and Strength in Hibernating Marmots
Fang_2016_Biosens.Bioelectron_87_545 Glutathione regulation-based dual-functional upconversion sensing-platform for acetylcholinesterase activity and cadmium ions
Jung_2016_Proc.Natl.Acad.Sci.U.S.A_113_E1098 Variable priming of a docked synaptic vesicle
Kostelnik_2016_Sensors.(Basel)_16_ Color Change of Phenol Red by Integrated Smart Phone Camera as a Tool for the Determination of Neurotoxic Compounds
Moreira_2016_Biosens.Bioelectron_87_607 Towards timely Alzheimer diagnosis: A self-powered amperometric biosensor for the neurotransmitter acetylcholine
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Simeon_2016_PeerJ_4_e2322 Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking
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Chen_2016_eNeuro_3_ Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum
Limebeer_2016_Behav.Neurosci_130_261 Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model
Wiley_2016_Behav.Pharmacol_27_479 Just add water: cannabinoid discrimination in a water T-maze with FAAH(-\/-) and FAAH(+\/+) mice
Wilkerson_2016_Br.J.Pharmacol_173_1678 Diacylglycerol lipase beta inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain
Wills_2016_Neuropsychopharmacology_41_1865 Double Dissociation of Monoacylglycerol Lipase Inhibition and CB1 Antagonism in the Central Amygdala, Basolateral Amygdala, and the Interoceptive Insular Cortex on the Affective Properties of Acute Naloxone-Precipitated Morphine Withdrawal in Rats
Alout_2016_Sci.Rep_6_29755 Interactive cost of Plasmodium infection and insecticide resistance in the malaria vector Anopheles gambiae
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Dobrovinskaya_2016_Front.Pharmacol_7_290 Cholinergic Machinery as Relevant Target in Acute Lymphoblastic T Leukemia
Gautam_2016_Ann.Neurosci_23_68 Assessment of Cholinergic Properties of Ashwagandha Leaf-Extract in the Amnesic Mouse Brain
Miao_2016_J.Insect.Sci_16_ Sublethal Effects of Insecticide Exposure on Megacopta cribraria (Fabricius) Nymphs: Key Biological Traits and Acetylcholinesterase Activity
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Zhang_2016_Nanoscale_8_16851 Artificial hydrolase based on carbon nanotubes conjugated with peptides
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Abdel-Ghany_2016_J.Toxicol_2016_5609734 Impact of Exposure to Fenitrothion on Vital Organs in Rats
Decker_2016_Molecules_21_ Special Issue: Molecules against Alzheimer
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Sirimangkalakitti_2016_Planta.Med_81_S1 Bromotyrosine alkaloids with acetylcholinesterase inhibitory activity from the Thai sponge Acanthodendrilla sp
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Adefegha_2016_J.Evid.Based.Complementary.Altern.Med_21_NP56 Modulatory Effects of Ferulic Acid on Cadmium-Induced Brain Damage
Ademosun_2016_J.Evid.Based.Complementary.Altern.Med_21_NP11 Antioxidative Properties and Effect of Quercetin and Its Glycosylated Form (Rutin) on Acetylcholinesterase and Butyrylcholinesterase Activities
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Dos_2016_Med.Chem_12_457 Chemical Composition and Inhibitory Effects of Hypericum brasiliense and H. connatum on Prolyl Oligopeptidase and Acetylcholinesterase Activities
Fawaz_2016_J.Med.Entomol_53_620 Pyrethroid Insecticide Resistance Mechanisms in the Adult Phlebotomus papatasi (Diptera: Psychodidae)
Gambardella_2016_Environ.Toxicol_31_1552 Review: Morphofunctional and biochemical markers of stress in sea urchin life stages exposed to engineered nanoparticles
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Jeremias_2016_Mol.Neurobiol_53_6635 The Role of Acetylcholine in the Inflammatory Response in Animals Surviving Sepsis Induced by Cecal Ligation and Puncture
Kalathiya_2016_Biotechnol.Appl.Biochem_63_765 Identification of 1H-indene-(1,3,5,6)-tetrol derivatives as potent pancreatic lipase inhibitors using molecular docking and molecular dynamics approach
Khadrawy_2016_Toxicol.Ind.Health_32_1711 Neurochemical impact of bisphenol A in the hippocampus and cortex of adult male albino rats
Kruger_2016_Oncotarget_7_51082 The anti-apoptotic PON2 protein is Wnt\/beta-catenin-regulated and correlates with radiotherapy resistance in OSCC patients
Lima_2016_Scand.J.Med.Sci.Sports_26_1160 Ibuprofen intake increases exercise time to exhaustion: A possible role for preventing exercise-induced fatigue
Liu_2016_J.Ethnopharmacol_194_475 Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use
Liu_2016_Mol.Neurobiol_53_4972 Activation of mTOR signaling mediates the increased expression of AChE in high glucose condition: in vitro and in vivo evidences
Mahfoudhi_2016_Chem.Biodivers_13_1747 Evaluation of Antioxidant, Anticholinesterase, and Antidiabetic Potential of Dry Leaves and Stems in Tamarix aphylla Growing Wild in Tunisia
Mandic_2016_Folia.Morphol.(Warsz)_75_188 The effects of quercetin on liver regeneration after liver resection in rats
Moodie_2016_Org.Biomol.Chem_14_11220 Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission
Muangphra_2016_Environ.Toxicol_31_1450 Chronic toxicity of commercial chlorpyrifos to earthworm Pheretima peguana
Paoletti_2016_Mol.Neurobiol_53_6316 Lysophosphatidylcholine Drives Neuroblast Cell Fate
Pena-Garcia_2016_Comb.Chem.High.Throughput.Screen_19_605 High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review
Prando_2016_Phytomedicine_23_1249 Involvement of bradykinin B2 and muscarinic receptors in the prolonged diuretic and antihypertensive properties of Echinodorus grandiflorus (Cham. & Schltdl.) Micheli
Ramirez-Velasco_2016_Comb.Chem.High.Throughput.Screen_19_616 From Classical to High Throughput Screening Methods for Feruloyl Esterases: A Review
Romero_2016_J.Med.Entomol_53_727 High Levels of Resistance in the Common Bed Bug, Cimex lectularius (Hemiptera: Cimicidae), to Neonicotinoid Insecticides
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Serrano_2016_Curr.Alzheimer.Res_13_1017 Rhein-Huprine Derivatives Reduce Cognitive Impairment, Synaptic Failure and Amyloid Pathology in AbetaPPswe\/PS-1 Mice of Different Ages
Song_2016_Neurosci.Lett_638_121 alpha-Isocubebenol alleviates scopolamine-induced cognitive impairment by repressing acetylcholinesterase activity
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Temeyer_2016_J.Med.Entomol_53_500 Tick Salivary Cholinesterase: A Probable Immunomodulator of Host-parasite Interactions
Tran_2016_J.Pediatr.Surg_51_2005 Diagnostic value of rectal suction biopsies using calretinin immunohistochemical staining in Hirschsprung's disease
Villanueva_2016_Neurologia_31_613 Dementia drug consumption in the Basque Country between 2006 and 2011
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Wang_2016_Aging.Clin.Exp.Res_28_951 Rapid eye movement sleep behavior disorder in patients with probable Alzheimer's disease
Wattanathorn_2016_Rejuvenation.Res_19_273 Novel Food Supplement CP1 Improves Motor Deficit, Cognitive Function, and Neurodegeneration in Animal Model of Parkinson's Disease
Wong_2016_Regul.Toxicol.Pharmacol_81 Suppl 2_S59 Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke
Wouters_2016_Int.J.Methods.Psychiatr.Res_25_190 Individualized evaluation of cholinesterase inhibitors effects in dementia with adaptive cognitive testing
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Arduini_2016_Sensors.(Basel)_17_ Organophosphorous Pesticide Detection in Olive Oil by Using a Miniaturized, Easy-to-Use, and Cost-Effective Biosensor Combined with QuEChERS for Sample Clean-Up
Canzian_2016_Behav.Brain.Res_320_255 Conspecific alarm substance differently alters group behavior of zebrafish populations: Putative involvement of cholinergic and purinergic signaling in anxiety- and fear-like responses
Chandrasekhar_2016_Biomed.Pharmacother_86_414 Antidepressant like effects of hydrolysable tannins of Terminalia catappa leaf extract via modulation of hippocampal plasticity and regulation of monoamine neurotransmitters subjected to chronic mild stress (CMS)
Delwing-de Lima_2016_Biomed.Pharmacother_86_686 The effect of d-galactose induced oxidative stress on in vitro redox homeostasis in rat plasma and erythrocytes
Fernandes_2016_World.J.Gastroenterol_22_9974 CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
Gavric_2016_Ecotoxicol.Environ.Saf_138_154 Oxidative stress biomarkers, cholinesterase activity and biotransformation enzymes in the liver of dice snake (Natrix tessellata Laurenti) during pre-hibernation and post-hibernation: A possible correlation with heavy metals in the environment
Grosskopf_2016_Exp.Parasitol_173_34 Supplementation with copper edetate in control of Haemonchus contortus of sheep, and its effect on cholinesterase's and superoxide dismutase activities
Han_2016_Chem.Biol.Interact_263_66 Hydrogen sulfide may attenuate methylmercury-induced neurotoxicity via mitochondrial preservation
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Kang_2016_J.Nat.Prod_79_3148 Ostalactones A-C, beta- and epsilon-Lactones with Lipase Inhibitory Activity from the Cultured Basidiomycete Stereum ostrea
Kim_2016_Chemosphere_171_520 Effects of sub-chronic exposure to lead (Pb) and ascorbic acid in juvenile rockfish: Antioxidant responses, MT gene expression, and neurotransmitters
Kumar_2016_Exp.Neurobiol_25_318 Chronic Nonmodulated Microwave Radiations in Mice Produce Anxiety-like and Depression-like Behaviours and Calcium- and NO-related Biochemical Changes in the Brain
Kuo_2016_Int.J.Nanomedicine_11_6809 Rescuing cholinergic neurons from apoptotic degeneration by targeting of serotonin modulator-and apolipoprotein E-conjugated liposomes to the hippocampus
Lin_2016_Biomed.J_39_391 The effectiveness of patient-tailored treatment for acute organophosphate poisoning
Louveau_2016_J.Anim.Sci_94_5042 Increased expressions of genes and proteins involved in mitochondrial oxidation and antioxidant pathway in adipose tissue of pigs selected for a low residual feed intake
Malekshah_2016_Curr.Pharmacol.Rep_2_299 Enzyme\/Prodrug Systems for Cancer Gene Therapy
Meirer_2016_Molecules_22_ Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase
Park_2016_PLoS.One_11_e0168978 Effects of Antifouling Biocides on Molecular and Biochemical Defense System in the Gill of the Pacific Oyster Crassostrea gigas
Rajakumar_2016_Microb.Pathog_103_123 Evaluation of anti-cholinesterase, antibacterial and cytotoxic activities of green synthesized silver nanoparticles using from Millettia pinnata flower extract
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Uthra_2016_Biomed.Pharmacother_86_705 Therapeutic potential of quercetin against acrylamide induced toxicity in rats
Walton_2016_Biomed.J_39_373 Pralidoxime and pesticide poisoning: A question of severity?
Zengin_2016_Biomed.Pharmacother_87_27 Euphorbia denticulata Lam.: A promising source of phyto-pharmaceuticals for the development of novel functional formulations
Zhang_2016_PLoS.One_11_e0168812 Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining
Bursteinas_2016_Database.(Oxford)_2016_ Minimizing proteome redundancy in the UniProt Knowledgebase
Wierdl_2016_Br.J.Pharmacol_173_2811 Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer
Deak_2016_Neurol.Clin.Pract_6_523 Memory loss: Five new things
Gounden_2016_Spinal.Cord.Ser.Cases_2_15037 Ocular myasthenia gravis in a person with tetraplegia presenting challenges in diagnosis and management
Maroyi_2016_Evid.Based.Complement.Alternat.Med_2016_1720123 From Traditional Usage to Pharmacological Evidence: Systematic Review of Gunnera perpensa L
Peng_2016_ACS.Omega_1_1182 Monoclonal Antibodies That Recognize Various Folding States of Pure Human Butyrylcholinesterase Can Immunopurify Butyrylcholinesterase from Human Plasma Stored at Elevated Temperatures
Freitas_2016_Harmful.Algae_55_150 Use of cholinesterase activity as an ecotoxicological marker to assess anatoxin-a(s) exposure: Responses of two cladoceran species belonging to contrasting geographical regions
Campanari_2016_Front.Mol.Neurosci_9_160 Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase
Mahmoudvand_2016_Iran.J.Parasitol_11_177 Acetylcholinesterase Inhibitor Improves Learning and Memory Impairment Induced by Toxoplasma gondii Infection
Patro_2016_Avicenna.J.Phytomed_6_696 Effects of Mimosa pudica L. leaves extract on anxiety, depression and memory
Amaral_2016_Curr.Neurovasc.Res_13_4 Endogenous Acetylcholine Controls the Severity of Polymicrobial Sepsisassociated Inflammatory Response in Mice
Beraldo_2016_J.Biol.Chem_291_21945 Regulation of Amyloid beta Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex
Jackson_2016_Can.J.Neurol.Sci_43_735 Commemorating John F. MacDonald and the Art of Being a Mentor
Kolisnyk_2016_J.Neurosci_36_6287 Cholinergic Regulation of hnRNPA2\/B1 Translation by M1 Muscarinic Receptors
Leite_2016_Brain.Behav.Immun_57_282 Vesicular acetylcholine transporter knock down-mice are more susceptible to inflammation, c-Fos expression and sickness behavior induced by lipopolysaccharide
Palmer_2016_Behav.Brain.Res_311_267 Mice deficient for striatal Vesicular Acetylcholine Transporter (VAChT) display impaired short-term but normal long-term object recognition memory
Roy_2016_FASEB.J_30_688 Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathologic conditions
Silva_2016_Pathophysiology_23_229 Reduced expression of VAChT increases renal fibrosis
Sugita_2016_Skelet.Muscle_6_31 VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions
Buchholz_2016_Chembiochem_17_2093 BioCatNet: A Database System for the Integration of Enzyme Sequences and Biocatalytic Experiments
Kang_2016_Oxid.Med.Cell.Longev_2016_6981595 Reversal of Trimethyltin-Induced Learning and Memory Deficits by 3,5-Dicaffeoylquinic Acid
O'Brien_2016_J.Psychopharmacol_31_147 Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology
Sharma_2016_Transl.Neurosci_7_98 Enhancing attention in neurodegenerative diseases: current therapies and future directions
Chowdhury_2016_Bioinformation_12_112 In vitro anti-acetylcholinesterase activity of an aqueous extract of Unicaria tomentosa and in silico study of its active constituents
Emad_2016_Pharmacol.Rep_69_300 Attenuation of stress induced memory deficits by nonsteroidal anti-inflammatory drugs (NSAIDs) in rats: Role of antioxidant enzymes
Nguyen_2016_Mycobiology_44_291 Evaluation of Antioxidant, Anti-cholinesterase, and Anti-inflammatory Effects of Culinary Mushroom Pleurotus pulmonarius
Ntalli_2016_J.Nematol_48_248 Acetic Acid, 2-Undecanone, and (E)-2-Decenal Ultrastructural Malformations on Meloidogyne incognita
Voorhees_2016_Front.Neurosci_10_590 Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds
Carelli-Alinovi_2016_Clin.Hemorheol.Microcirc_64_679 Vascular dysfunction-associated with Alzheimer's disease
Choi_2016_Oncotarget_7_75319 Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase
Esteves_2016_Clin.Hemorheol.Microcirc_64_989 Erythrocyte nitric oxide in glaucoma patients - ex vivo study
Luo_2016_Protein.Pept.Lett_23_1032 Functions of Type II Thioesterases in Bacterial Polyketide Biosynthesis
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Mongalo_2016_J.Ethnopharmacol_194_789 Ethnobotany, phytochemistry, toxicology and pharmacological properties of Terminalia sericea Burch. ex DC. (Combretaceae) - A review
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Hirano_2016_Metabolism_65_893 Anagliptin, a dipeptidyl peptidase-4 inhibitor, decreases macrophage infiltration and suppresses atherosclerosis in aortic and coronary arteries in cholesterol-fed rabbits
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Knoblich_2016_Sci.Am_316_26 Lab-Built Brains
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