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Type_substrate Report for: pyrethroid

The targets of pyrethroids are not Alpha/beta hydrolases. The synthetic pyrethroids delay closure of the sodium channel, resulting in a sodium tail current that is characterized by a slow influx of sodium during the end of depolarization. Carboxylesterases are involved in elimination of Pyrethroids and mutations can enhance resistance to pyrethroids
See also this moiety in type of inhibitors: pyrethroid

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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