Type Substrate

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Type_substrate Report for: Natural

Substrates or inhibitors found in nature. Toxins are harmful substances produced within living cells or organisms
See also this moiety in type of inhibitors: Natural

Substrate	Main targeted enzyme families	Type

1,3,6-Trigalloylglucose	Tannase \| Tannase_Bact	Derivative of Gallate \| Natural \| Polyphenol

1,5-Seco-vibralactone	Hormone-sensitive_lipase_like	Lactone \| Natural

1-Oleoyl-2-arachidonoyl-sn-glycerol	Lipase_3	Acyl-Glycerol \| Natural

1-Stearoyl-2-arachidonoylglycerol	Lipase_3	Acyl-Glycerol \| Natural

15-Hete-G		Acyl-Glycerol \| Cannabinoid-Receptor-ligand \| Natural

2-Arachidonylglycerol	ABHD12-PHARC \| ABHD6-Lip \| Carb_B_Chordata \| Monoglyceridelipase_lysophospholip \| abh_upf0017	Acyl-Glycerol \| Cannabinoid-Receptor-ligand \| Natural

2-Heptyl-3-hydroxy-4-quinolone	HOD-cofactorfree-dioxygenase	Natural \| Quinoline

2-Heptylquinolin-4(1H)-one	HOD-cofactorfree-dioxygenase	Natural \| Quinoline

2-Monoolein	abh_upf0017	Acyl-Glycerol \| Natural

3-Methyl-3-butenyl-acetate		Acetate \| Natural

3-Oxoheptanoic-acid	Hydroxynitrile_lyase	Fatty acid \| Natural

4-Acetoxyphenol	Hormone-sensitive_lipase_like	Aryl ester \| Natural

4-Deoxyorobanchol	RsbQ-like	Inden \| Natural \| Plant hormone \| Strigolactone \| Strigolactone receptors ligand

5-Deoxystrigol	Plant_carboxylesterase \| RsbQ-like	Inden \| Natural \| Plant hormone \| Strigolactone \| Strigolactone receptors ligand

6-Tuliposide-A	Plant_carboxylesterase	Carbohydrate \| Natural

6-Tuliposide-B	Plant_carboxylesterase	Carbohydrate \| Natural

6-monoacetylmorphine	BCHE	Alkaloid \| Drug \| Isoquinoline \| Natural

7-Aminocephalosporanic-acid	Acetyl-esterase_deacetylase \| BD-FAE	Antibiotic \| Natural

Acetylcholine	ACHE \| BCHE \| Cholinesterase \| Cholinesterase-like	Acetate \| Choline ester \| Natural \| Trimethylammonium

Alpha-amanitin-proprotein	S9N_PPCE_Peptidase_S9	Macrocycle \| Natural \| Peptide \| Toxin

Alpha-zearalenol	Zearalenone-hydrolase	Macrolide \| Mycotoxin-metabolite \| Natural \| Toxin

Bacteriochlorophyll-a	Chlorophyllase \| Chlorophyllase_Plant	Chlorophyll-like \| Natural

Benzyl-butyl-phthalate	Cutinase \| Fungal_carboxylesterase_lipase	Natural \| Phthalate

Beta-zearalenol	Zearalenone-hydrolase	Macrolide \| Mycotoxin-metabolite \| Natural \| Toxin

BrefeldinA	Hormone-sensitive_lipase_like	Antibiotic \| Macrocycle \| Natural \| Toxin

Caffeoylshikimate	Monoglyceridelipase_lysophospholip	Natural

Cephalosporin-C	Acetyl-esterase_deacetylase \| BD-FAE \| Homoserine_transacetylase	Antibiotic \| Natural

Chlorogenic-acid	AlphaBeta_hydrolase \| FaeC \| Fungal_carboxylesterase_lipase \| Hormone-sensitive_lipase_like \| Monoglyceridelipase_lysophospholip \| Plant_carboxylesterase \| Tannase	Hydroxycinnamic-ester \| Natural

Chlorophyll-a	Chlorophyllase \| Chlorophyllase_Plant \| Pheophytinase	Chlorophyll-like \| Natural

Cholesterol	PC-sterol_acyltransferase	Natural \| Steroid

Cinnamic-acid	FAE-Bacterial-promiscuous	Natural

Cocaine	BCHE \| Carb_B_Chordata \| Cocaine_esterase	Alkaloid \| Benzoate \| Drug \| Natural

Coelenterazine	Haloalkane_dehalogenase-HLD2	Luciferin \| Natural

Coumarin-3-carboxylic-acid	FAE-Bacterial-promiscuous	Coumarin \| Natural

Cutin	Acetylxylan_esterase \| Cutinase \| Polyesterase-lipase-cutinase	Natural \| Polymer

DHDMP	MpaH	Benzofuran \| Natural

DSHA	Carbon-carbon_bond_hydrolase	Inden \| Natural

Deacetylcephalosporin-C	Homoserine_transacetylase	Antibiotic \| Natural

E-2-hexenyl-acetate	Carb_B_Arthropoda \| Plant_carboxylesterase	Acetate \| Natural \| Plant volatile

Epicatechin-gallate	AlphaBeta_hydrolase \| Plant_carboxylesterase	Benzoate \| Derivative of Gallate \| Natural \| Polyphenol

Epigallocatechin-gallate	AlphaBeta_hydrolase \| Plant_carboxylesterase	Benzoate \| Derivative of Gallate \| Natural \| Polyphenol

Ethyl-cinnamate	FAE-Bacterial-promiscuous \| Lipase_3	Natural

Fumonisin-B1	Carb_B_Bacteria	Mycotoxin-metabolite \| Natural \| Toxin

Geranyl-acetate	Canar_LipB \| Carb_B_Arthropoda	Acetate \| Alkenyl ester \| Natural \| Plant volatile

Gibberellin-A3	Plant_carboxylesterase	Natural \| Plant hormone

Gibberellin-A4	Plant_carboxylesterase	Natural \| Plant hormone

Gossypol	Carb_B_Arthropoda	Insecticide \| Natural \| Polyphenol

Hepoxilin-A3	Epoxide_hydrolase	Epoxide \| Fatty acid \| Natural

Hepoxilin-B3	Epoxide_hydrolase	Epoxide \| Fatty acid \| Natural

Heroin	BCHE \| Carb_B_Chordata	Alkaloid \| Drug \| Isoquinoline \| Natural

Hexylacetate	Carb_B_Arthropoda	Acetate \| Alkyl ester \| Natural \| Plant volatile

Juvenile-hormone-II	Epoxide_hydrolase	Epoxide \| Lactone \| Natural

Juvenile-hormone-III	Epoxide_hydrolase \| Juvenile_hormone_esterase	Epoxide \| Lactone \| Natural

Karrikin-1	RsbQ-like	Butenolide \| Karrikin \| Natural \| Plant hormone \| Strigolactone receptors ligand

Karrikin-2	RsbQ-like	Butenolide \| Karrikin \| Natural \| Plant hormone \| Strigolactone receptors ligand \| desmethyl Strigolactone receptors ligand

Karrikin-3	RsbQ-like	Butenolide \| Karrikin \| Natural \| Plant hormone \| Strigolactone receptors ligand

Karrikin-4	RsbQ-like	Butenolide \| Karrikin \| Natural \| Plant hormone \| Strigolactone receptors ligand

MeGlcA	Glucuronoyl_esterase	Carbohydrate \| Glucuronoyl \| Natural

MeGlcA2	Glucuronoyl_esterase	Carbohydrate \| Glucuronoyl \| Natural

Menthol	Fungal_carboxylesterase_lipase \| Hormone-sensitive_lipase_like	Natural

Methyl-farnesoate	Carb_B_Arthropoda \| Juvenile_hormone_esterase	Natural

Methyl-salicylate	Hydroxynitrile_lyase	Aryl ester \| Benzoate \| Natural \| Plant hormone \| Salicylic

Mycophenolic-acid-CoA	MpaH	Aminopurin \| Benzofuran \| CoA \| Natural

Mycotoxin-T-2	Carb_B_Chordata \| Hormone-sensitive_lipase_like	Mycotoxin-metabolite \| Natural \| Toxin

Myristic-acid	Pectinacetylesterase-Notum	Fatty acid \| Natural

N-acetylanthranilate	HOD-cofactorfree-dioxygenase \| Hormone-sensitive_lipase_like	Benzoate \| Natural

O-palmitoleoyl-L-serine	Pectinacetylesterase-Notum	Acyl peptide \| Natural

ORFZ-Substrate	Duf_1100-S	Mycotoxin-metabolite \| Natural \| Toxin

Octylacetate	Carb_B_Arthropoda	Acetate \| Alkyl ester \| Natural \| Plant volatile

Oleoyl-CoA	Carb_B_Chordata \| Carboxylesterase	Aminopurin \| CoA \| Natural

Omphalotin-A	S9N_PPCE_Peptidase_S9	Antibiotic \| Macrolide \| Natural \| Peptide

Orobanchol	Plant_carboxylesterase \| RsbQ-like	Natural \| Plant hormone \| Strigolactone \| Strigolactone receptors ligand

P(3HO)	5_AlphaBeta_hydrolase \| Extracel-MCL-phaZ \| PHAZ7_phb_depolymerase	Natural \| Polyhydroxyalkanoate \| Polymer

P(6HO)	5_AlphaBeta_hydrolase	Natural \| Polyhydroxyalkanoate \| Polymer

PAF	LYsophospholipase_carboxylesterase \| PAF-Acetylhydrolase	Choline ester \| Natural \| Not A/B H target \| Trimethylammonium \| Water-insoluble medium and long chain ester

PGE2-glyceryl-ester	ABHD12-PHARC \| ABHD6-Lip \| Carb_B_Chordata \| Monoglyceridelipase_lysophospholip	Acyl-Glycerol \| Cannabinoid-Receptor-ligand \| Natural \| Prostaglandin

Pentagalloylglucose	Plant_carboxylesterase	Derivative of Gallate \| Natural \| Polyphenol

Phaeophytin-a	Chlorophyllase \| Chlorophyllase_Plant \| Pheophytinase	Chlorophyll-like \| Natural

Pimaricin	Thioesterase	Antibiotic \| Macrolide \| Natural

Prostaglandin-D2-Glyceryl-Ester	Carb_B_Chordata	Acyl-Glycerol \| Cannabinoid-Receptor-ligand \| Natural \| Prostaglandin

PyiE-Substrate	Duf_1100-S	Mycotoxin-metabolite \| Natural \| Toxin

Retinol-acetate		Acetate \| Natural \| Retinol ester

Retinol-oleate	Cholesterol_esterase \| Pancreatic_lipase	Natural \| Retinol ester

Retinol-palmitate	Acidic_Lipase \| Carb_B_Chordata \| Cholesterol_esterase \| Fungal_carboxylesterase_lipase \| Pancreatic_lipase	Hexadecanoate \| Natural \| Retinol ester

Rifampicin	Arylacetamide_deacetylase	Acetate \| Antibiotic \| Drug \| Natural \| Not A/B H target

Rosmarinic-acid	Hormone-sensitive_lipase_like	Hydroxycinnamic-ester \| Natural

Skyllamycin-A	Thioesterase	Antibiotic \| Macrolide \| Natural \| Peptide

Skyllamycin-like-precursor	Thioesterase	Antibiotic \| Macrolide \| Natural \| Peptide

Sorgolactone	RsbQ-like	Inden \| Natural \| Plant hormone \| Strigolactone \| Strigolactone receptors ligand

Stearic-acid		Fatty acid \| Natural

Strigol	RsbQ-like	Inden \| Natural \| Plant hormone \| Strigolactone \| Strigolactone receptors ligand

Suberin	Cutinase	Natural \| Polymer

Thiostrepton	6_AlphaBeta_hydrolase	Antibiotic \| Macrocycle \| Natural \| Peptide \| Quinoline

Tiancimycin-H	Tiancimycin-TnmK-Tripeptidase-HIP	Antibiotic \| Natural \| Polyketide

Undecanoic-acid	ABHD6-Lip	Fatty acid \| Natural

Z-3-Hexenyl-acetate	Carb_B_Arthropoda \| Plant_carboxylesterase	Acetate \| Natural \| Odorant \| Plant volatile

Zearalenone	Carbon-carbon_bond_hydrolase \| Zearalenone-hydrolase	Macrolide \| Mycotoxin-metabolite \| Natural \| Toxin

delta-hexadecalactone	Canar_LipB	Hexadecanoate \| Lactone \| Natural \| Pheromone

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

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