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Type_substrate Report for: Monoacylglycerol

Monoglycerides (also: acylglycerols or monoacylglycerols) are a class of glycerides which are composed of a molecule of glycerol linked to a fatty acid via an ester bond. As glycerol contains both primary and secondary alcohol groups two different types of monoglycerides may be formed; 1-monoacylglycerols where the fatty acid is attached to a primary alcohol, or a 2-monoacylglycerols where the fatty acid is attached to the secondary alcohol. Monoacylglycerols are substrates of lipases. They results from the hydrolysis of triglycerides by lipoprotein lipase and the enzymatic hydrolysis of diglycerides by diacylglycerol lipase
See also this moiety in type of inhibitors: Monoacylglycerol

SubstrateMain targeted enzyme familiesTypeStructure
Arachidonoyl-1-thioglycerolABHD6-Lip | Carb_B_Chordata | Hormone-sensitive_lipase_like | Lipase_3 | Monoglyceridelipase_lysophospholip | Plasmodium_subtelomeric_PST-A Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
Glyceryl-monolinoleateABHD16 Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
MonocaprinAcidic_Lipase | BCHE | Carb_B_Chordata | Lipase_3 | abh_upf0017 Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
MonolaurinAcidic_Lipase | CarbLipBact_2 | abh_upf0017 Acyl-Glycerol | Dodecanoate | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
MonomyristinAcidic_Lipase | Lipase_3 | abh_upf0017 Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Tetradecanoate | Water-insoluble medium and long chain ester
MonooctanoinAcidic_Lipase | Carb_B_Chordata Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Octanoate
MonooleinAcidic_Lipase | Carb_B_Chordata | Lipase_3 | Monoglyceridelipase_lysophospholip | abh_upf0017 Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
MonopalmitinAcidic_Lipase | abh_upf0017 Acyl-Glycerol | Fatty acid ester | Hexadecanoate | Monoacylglycerol | Water-insoluble medium and long chain ester
MonostearinCarb_B_Chordata | Monoglyceridelipase_lysophospholip Acyl-Glycerol | Fatty acid ester | Monoacylglycerol | Water-insoluble medium and long chain ester
NBD-MAGHormone-sensitive_lipase_like Benzoxadiazole | Dodecanoate | Fatty acid ester | Fluorescent Probe | Monoacylglycerol | NBD-nitro-benzoxadiazol-fluorescent | Water-insoluble medium and long chain ester

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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