Type Inhibitor

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Type_inhibitor Report for: Quinoline

Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N. 1-Benzopyridine. Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme families	Type

(Isoquinolin-1-ylsulfanyl)-acetic-acid	Pectinacetylesterase-Notum	Fragment inhibitor of Notum \| Isoquinoline \| Quinoline \| Sulfur Compound

(R)-Tacrine(10)-Hupyridone	ACHE	Alkyl linked bis-ligand \| Derivative of Huperzine \| Derivative of Tacrine \| Quinoline

(S,S)-(-)-bis(10)-hupyridone	ACHE	Alkyl linked bis-ligand \| Derivative of Huperzine \| Quinoline

(S,S)-(-)-bis(12)-hupyridone	ACHE	Alkyl linked bis-ligand \| Derivative of Huperzine \| Quinoline

40V	BCHE	Carboxamide \| Inden \| Metal ion chelator \| Multitarget \| Piperidine \| Quinoline

6F7Q-cpd11	BCHE	Antioxidant \| Carboxamide \| Inden \| Metal ion chelator \| Multitarget \| Piperidine \| Quinoline

8012-9656	BCHE	Benzimidazole \| Imidazole \| Oxadiazol \| Quinoline

8U2-7AIX7AY-compound5i	ACHE \| BCHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

8U5-7AIW-compound5g	ACHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

8UE-7AIV-compound5f	ACHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

8UH-7AIS-compound5b	ACHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

8UK-7AIT-compound5c	ACHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

8UQ-7AIU-compound5d	ACHE	Alkyl linked bis-ligand \| Antioxidant \| Derivative of Capsaicin \| Derivative of Huperzine \| Multitarget \| Quinoline

AI0-7QBQ	BCHE	Monoamine-oxidase-inhibitor \| Multitarget \| Quinoline

AI6-7QBR	BCHE	Monoamine-oxidase-inhibitor \| Multitarget \| Piperazine \| Quinoline \| tert-Butyl

Acridine	ACHE	Acridine \| Quinoline

Amodiaquine	ACHE	Drug \| Not A/B H target \| Quinoline

CD-Bzl	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural_modified \| Quinoline

CHEMBL1951424	DPP4N_Peptidase_S9	Cyanide \| Piperidine \| Pyrrolidine \| Quinoline

CHEMBL2058971	DPP4N_Peptidase_S9	Pyrrolidine \| Quinoline \| Sulfur Compound \| Thiazolidine \| Trifluoro

CHEMBL3125346	Cholesterol_esterase	Quinoline

CHEMBL3125351	Cholesterol_esterase	Quinoline

Cinchonidine	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural \| Quinoline

Cinchonine	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural \| Quinoline

Compound19n-quinolinol		Derivative of Donepezil \| Metal ion chelator \| Multitarget \| Quinoline \| Trifluo \| anti-Abeta-aggregation

Cpd8f-quinoline-carboxamide	Hormone-sensitive_lipase_like	Carboxamide \| Quinoline

DEPQ	ACHE	Organophosphate \| Quinoline

DPH6	ACHE \| BCHE	Derivative of Donepezil \| Monoamine-oxidase-inhibitor \| Multitarget \| Quinoline

Di-tert-butyl-4-Amino-2,3-cycloheptaquinoline-8c	BCHE	Antioxidant \| Multitarget \| Quinoline \| tert-Butyl

Dibucaine	BCHE	Carboxamide \| Drug \| Local anesthetic \| Not A/B H target \| Quinoline

Donepezil-8-Hydroxyquinoline-2b	BCHE	Antioxidant \| Derivative of Donepezil \| Multitarget \| Quinoline

Duador	BCHE	Neuromuscular Nondepolarizing Agents \| Not A/B H target \| Pyrrolidine \| Quinoline

Emetine	Hydrolase_RBBP9_YdeN	Alkaloid \| Drug \| Isoquinoline \| Natural \| Quinoline

FAPI-04	DPP4N_Peptidase_S9	Carboxamide \| PET probe \| Piperazine \| Quinoline

FBQ	ACHE	Derivative of Tacrine \| Quinoline \| Sulfur Compound \| Transition state analogue \| Trifluoro

HuprineW	ACHE	Derivative of Huperzine \| Derivative of Tacrine \| Natural_modified \| Quinoline

HuprineX	ACHE	Derivative of Huperzine \| Derivative of Tacrine \| Natural_modified \| Quinoline

Hupyridone	ACHE	Derivative of Huperzine \| Quinoline

JMN4	PAF-Acetylhydrolase	Piperazine \| Quinoline

JS0-7ZPB	BCHE	Monoamine-oxidase-inhibitor \| Multitarget \| Piperazine \| Quinoline

M30D	ACHE	Carbamate \| Monoamine-oxidase-inhibitor \| Multitarget \| Quinoline

MEPQ	ACHE	Organophosphate \| Quinoline

N-Methyl-7-dimethylcarbamoxyquinolinium	ACHE \| BCHE	Carbamate \| Quinoline

N-Methyl-7-hydroxyquinolinium	BCHE	Quinoline

NIK-247	ACHE \| BCHE	Derivative of Tacrine \| Quinoline

S06-1011	BCHE	Benzimidazole \| Imidazole \| Oxadiazol \| Quinoline

SB31184-49R-4Y2U	Epoxide_hydrolase	Carbamate \| Quinoline \| tert-Butyl \| tert-Butyloxycarbonyl

ST052207	BCHE	Carbazol \| Quinoline

T-82(1)	ACHE	Piperidine \| Quinoline

TZ2PIQA5		Acridine \| Alkyl linked bis-ligand \| Derivative of Tacrine \| Quinoline \| Triazol

Tacrine(8)-4-aminoquinoline	ACHE	Alkyl linked bis-ligand \| Derivative of Tacrine \| Quinoline

Tacrine-dihydropyrimidine-4e	ACHE	Calcium Channel Antagonist \| Derivative of Tacrine \| Multitarget \| Pyrimidine \| Quinoline \| Sulfur Compound

VL1-8MH	Haloalkane_dehalogenase-HLD2	Fluorescent Probe \| HaloTag-ligand \| Isoquinoline \| Quinoline

WMY90-5f	ACHE	Derivative of Donepezil \| Monoamine-oxidase-inhibitor \| Multitarget \| Quinoline

WWL153	PAF-Acetylhydrolase	Piperazine \| Quinoline \| pNP

ZINC20166201-cpd8	BCHE	Piperazine \| Quinoline

beta-lactam-A295		Piperazine \| Quinoline

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

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