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Type_inhibitor Report for: PET probe

Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. Radionuclides used in PET scanning are typically isotopes with short half-lives such as carbon-11 (20 min), nitrogen-13 (10 min), oxygen-15 (2 min), fluorine-18 (110 min), gallium-68 (~67 min), zirconium-89 (78.41 hours), or rubidium-82(1.27 min). These radionuclides are incorporated either into compounds

InhibitorMain targeted enzyme familiesTypeStructure
123I-PIPBCHE Carbamate | PET probe
5DYW-5hf-C11BCHE Derivative of Donepezil | Naphthalen | PET probe | Piperidine | Sulfonamide | Sulfur compound
5DYW-5hf-FBCHE Derivative of Donepezil | PET probe | Piperidine | Sulfonamide | Sulfur compound
64DMonoglyceridelipase_lysophospholip PET probe | Piperidine | Sulfonyl | Sulfur compound
CHEMBL4454960-PETBCHE Carbamate | PET probe
FAPI-04DPP4N_Peptidase_S9 Carboxamide | PET probe | Piperazine | Quinoline
FEPADMonoglyceridelipase_lysophospholip Azetidin | PET probe | Piperazine | Sulfur compound | Thiazolidine | Trifluoro
FNDPEpoxide_hydrolase Carboxamide | PET probe
JZP-MA-11ABHD6-Lip Carbamate | PET probe | Piperidine | Sulfur compound | Thiadiazol
PF-06795071Monoglyceridelipase_lysophospholip Carbamate | PET probe | Pyrazole | Trifluoro
Pyridophen-10ACHE Carbamate | Multitarget | Muscarinic antagonist | Not A/B H target | PET probe | Pro-Drug | Propionate
SCHEMBL22462761Monoglyceridelipase_lysophospholip Azetidin | PET probe | Trifluoro | Urea derivative
T-401Monoglyceridelipase_lysophospholip PET probe | Piperazine | Pyrrolidine | Sulfur compound
Tetracyclic-carbamate-cp8BCHE Carbamate | Derivative of Evodiamine | Isoquinoline | Natural_modified | PET probe
VXSACHE | BCHE Derivative of Paraoxon | Derivative of VX | Organophosphate | PET probe | pNP
YH149Monoglyceridelipase_lysophospholip PET probe | Piperazine | Pyrrolidine
ZYH-deriv-FMonoglyceridelipase_lysophospholip Azetidin | Carboxamide | PET probe | Piperazine | Pyrimidine
[11C]N-methyl-tacrineACHE Acridine | Derivative of Tacrine | PET probe

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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