Type_inhibitor Report for: Natural_modified

Compounds that are derived from a natural substance in order to reduce its toxicity or enhance its specificity for a particular target

Inhibitor	Main targeted enzyme families	Type

5-deoxo-3-hydroxyevodiamine-heptyl-carbamate	BCHE	Carbamate \| Derivative of Evodiamine \| Natural_modified

BysspectinA-cpd20wderivative	Carb_B_Chordata	Benzofuran \| Natural_modified

CD-Bzl	BCHE	Alkaloid \| Derivative of Cinchonine \| Natural_modified \| Quinoline

D45K-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

Dehydroevodiamine	ACHE	Derivative of Evodiamine \| Natural \| Natural_modified \| Pyridine \| beta-carboline

Fasciculin2	ACHE	Fasciculin2 variant \| Natural \| Natural_modified \| Peptide

Galanthaminium	ACHE	Alkaloid \| Derivative of Galanthamine \| Natural_modified

H29D-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

HuprineW	ACHE	Derivative of Huperzine \| Derivative of Tacrine \| Natural_modified \| Quinoline

HuprineX	ACHE	Derivative of Huperzine \| Derivative of Tacrine \| Natural_modified \| Quinoline

K25L-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

K32G-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

K51S-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

M33A-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

Memogain	ACHE \| Carb_B_Chordata	Alkaloid \| Benzoate \| Derivative of Galanthamine \| Natural_modified

N-piperidinopropylgalanthamine	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Natural_modified \| Piperidine

N-saccharinohexylgalanthamine	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Natural_modified \| Sulfur compound

P30del-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

P31R-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

Peganine	ACHE \| BCHE	Alkaloid \| Natural_modified \| Not A/B H target

Phthalimido-Galanthaminium-4d	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Isoindole \| Natural_modified \| Phthalimido

Phthalimido-Galanthaminium-8d	ACHE	Alkaloid \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Isoindole \| Natural_modified \| Phthalimido

Physostigmine-methiodide	ACHE	Carbamate \| Derivative of physostigmine-eserine \| Natural_modified

R11Q-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

R24T-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

R27W-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

R28D-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

T8A,T9A-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

Tetracyclic-carbamate-cp8	BCHE	Carbamate \| Derivative of Evodiamine \| Isoquinoline \| Natural_modified \| PET probe

Tetracyclic-triterpene-1	ACHE	Natural_modified \| Terpenoid

Tetracyclic-triterpene-36e	ACHE	Natural_modified \| Terpenoid \| anti-Abeta-aggregation

V34A,L35A-fasciculin2	ACHE	Fasciculin2 variant \| Natural_modified \| Peptide

XB8-8CGO	BCHE	Alkaloid \| Natural_modified

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

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