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Type_inhibitor Report for: Cyclic OP

Cyclic Organophosphates. First natural OPs were isolated from the mycelium of Streptomyces species. Cyclophostin-like and Cyclipostin-like are promising compounds in the fight against tuberculosis. This type also contains Phenyl-saligenin-phosphate a potent delayed neurotoxin

InhibitorMain targeted enzyme familiesTypeStructure
CBDPACHE | BCHE | Carb_B_Chordata Cyclic OP | NTE inhibitor | Not A/B H target | Organophosphate
CGA-134-735ACHE Cyclic OP | Natural | Organophosphate
CGA-134-736ACHE Cyclic OP | Natural | Organophosphate
CyC-17A85-Mycolyl-transferase | Carbon-carbon_bond_hydrolase | Cutinase | Hormone-sensitive_lipase_like | Thioesterase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-31Carbon-carbon_bond_hydrolase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-31-openCarbon-carbon_bond_hydrolase Cyclic OP | Cyclic OP open | Lipase inhibitor | Organophosphate
CyC-31yneCarbon-carbon_bond_hydrolase Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
CyC-32Carbon-carbon_bond_hydrolase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-32yneCarbon-carbon_bond_hydrolase Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
CyC-7betaA85-Mycolyl-transferase Cyclic OP | Lipase inhibitor | Organophosphate
CyC-8betaA85-Mycolyl-transferase Cyclic OP | Lipase inhibitor | Organophosphate
CyclipostinHormone-sensitive_lipase_like Cyclic OP | Organophosphate
Cyclipostin-PCutinase | Hormone-sensitive_lipase_like | Monoglyceridelipase_lysophospholip Cyclic OP | Lipase inhibitor | Natural | Organophosphate
CyclophostinACHE Cyclic OP | Natural | Organophosphate
Cyclophostin-enolphosphonateCutinase | Monoglyceridelipase_lysophospholip Cyclic OP | Lipase inhibitor | Organophosphate
OBDPO Cyclic OP | NTE inhibitor | Not A/B H target | Organophosphate
Phenyl-BDPO Cyclic OP | NTE inhibitor | Not A/B H target | Organophosphate
Phenyl-saligenin-phosphate~PSPBCHE Cyclic OP | NTE inhibitor | Not A/B H target | Organophosphate
S9B Biotin derivative | Cyclic OP | NTE inhibitor | Not A/B H target | Organophosphate | Sulfur Compound
Sal-A-alkyneABHD13-BEM46 | ABHD17-depalmitoylase | Duf_676 | PGAP1 | Plasmodium_subtelomeric_PST-A ABPP-Probe | Alkyne | Cyclic OP | Lipase inhibitor | Organophosphate
Salinipostin-AABHD13-BEM46 | ABHD17-depalmitoylase | Duf_676 | PGAP1 | Plasmodium_subtelomeric_PST-A Cyclic OP | Lipase inhibitor | Natural | Organophosphate
SalioxonBCHE Cyclic OP | Organophosphate
SalithionBCHE Cyclic OP | Organophosphate | Sulfur Compound

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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