Type_inhibitor Report for: Adamantyl

Fusion of three cyclohexane rings, found naturally in petroleum. It is an element of many drugs memantine, saxagliptin, vildagliptin

Inhibitor	Main targeted enzyme families	Type

5ALU-HD2	Epoxide_hydrolase	Adamantyl \| Carboxamide \| Not A/B H target \| Pyrimidine \| Urea derivative

5ALZ-XQ9	Epoxide_hydrolase	Adamantyl \| Piperidine \| Sulfonamide \| Sulfonyl \| Sulfur compound \| Urea derivative

7-methoxytacrine-memantine-Cpd4	ACHE	Adamantyl \| Alkyl linked bis-ligand \| Multitarget \| NMDA-ligand \| Urea derivative

AEPU	Epoxide_hydrolase	Adamantyl \| Urea derivative

ARN14140	ACHE	Adamantyl \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Multitarget \| NMDA-ligand

ARN14140-doubleboundlink	ACHE	Adamantyl \| Alkyl linked bis-ligand \| Derivative of Galanthamine \| Multitarget \| NMDA-ligand

AUDA	Epoxide_hydrolase	Adamantyl \| Dodecanoate \| Urea derivative

Adamantyl-ebselen	A85-Mycolyl-transferase	Adamantyl \| Organoselenium \| Thiol-reactive

Adamantyl-urea-Cpd28	Epoxide_hydrolase	Adamantyl \| Urea derivative

Amantadine-M30D-hybrid5e	BCHE	Adamantyl \| Alkyl linked bis-ligand \| Carbamate \| Monoamine-oxidase-inhibitor \| Multitarget

Ar9281	Epoxide_hydrolase	Adamantyl \| Urea derivative

B401	Epoxide_hydrolase	Adamantyl \| Piperidine \| Urea derivative

CHEMBL1818384	Epoxide_hydrolase	Adamantyl \| Urea derivative

CHEMBL3402240-4A0-4Y2X	Epoxide_hydrolase	Adamantyl

CHEMBL3633668	Epoxide_hydrolase	Adamantyl \| Urea derivative

CS38	Palmitoyl-protein_thioesterase	Adamantyl \| Benzoate \| Triazol

HyT13	Haloalkane_dehalogenase-HLD2	Adamantyl

Indol-adamantyl-carbamate-Cpd42	DPP4N_Peptidase_S9	Adamantyl \| Carbamate \| Gliptin \| Indole

N-1-adamantyl-N'-cyclohexylurea	Epoxide_hydrolase	Adamantyl \| Urea derivative

Saxagliptin	DPP4N_Peptidase_S9	Adamantyl \| Cyanide \| Drug \| Gliptin \| Pyrrolidine

UB-EV-52	Epoxide_hydrolase	Adamantyl \| Urea derivative

VildaSaxagliptin-analogue	DPP4N_Peptidase_S9	Adamantyl \| Gliptin \| Pyrrolidine

Vildagliptin	DPP4N_Peptidase_S9	Adamantyl \| Drug \| Gliptin \| Pyrrolidine

benzohomoadamantane-chlorotacrine-18a	ACHE	Adamantyl \| Derivative of Tacrine \| Multitarget \| NMDA-ligand

benzohomoadamantane-chlorotacrine-18b	ACHE \| BCHE	Adamantyl \| Alkyl linked bis-ligand \| Derivative of Tacrine \| Multitarget \| NMDA-ligand

nbAUDA	Epoxide_hydrolase	Adamantyl \| Dodecanoate \| Urea derivative

t-AUCB	Epoxide_hydrolase	Adamantyl \| Urea derivative

t-AUCMB	Epoxide_hydrolase	Adamantyl \| Multitarget \| Urea derivative

triazole-aryl-adamantane-Cpd32	ACHE	Adamantyl \| Multitarget \| NMDA-ligand \| Triazol

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

webmaster

Acknowledgements and disclaimer