Type_inhibitor Report for: 5-HT-receptor-ligand

Not an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compounds

Inhibitor	Main targeted enzyme families	Type

5-hydroxy-tryptamine	ACHE \| BCHE	5-HT-receptor-ligand \| Derivative of Tryptamine \| Natural \| Not A/B H target

6o-5-HT3	ACHE \| BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Carboxamide \| Derivative of Tacrine \| Multitarget

Cpd14-BChEin-5-HT6	BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Indole \| Multitarget \| Sulfur Compound

Cpd17-Tacrine-5-HT6	ACHE \| BCHE	5-HT-receptor-ligand \| Acridine \| Alkyl linked bis-ligand \| Derivative of Tacrine \| Indole \| Multitarget \| Sulfur Compound \| anti-Abeta-aggregation

Cpd27-BChEin-5-HT6	BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Indole \| Multitarget \| Sulfur Compound

Cpd35-Rivastigmine-5-HT6	BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Carbamate \| Derivative of Rivastigmine \| Indole \| Multitarget \| Sulfur Compound \| anti-Abeta-aggregation

Cpd54-BChEin-5-HT6	BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Indole \| Multitarget \| Sulfur Compound \| tert-Butyl \| tert-Butyloxycarbonyl

Cpd70-BChEin-5-HT6	BCHE	5-HT-receptor-ligand \| Alkyl linked bis-ligand \| Indole \| Multitarget

Donecopride	ACHE	5-HT-receptor-ligand \| Derivative of Donepezil \| Multitarget \| Piperidine

Idalopirdine-rivastigmine	BCHE	5-HT-receptor-ligand \| Carbamate \| Derivative of Rivastigmine \| Drug \| Multitarget \| Pro-Drug

RS67333	ACHE	5-HT-receptor-ligand \| Multitarget \| Piperidine

Sigma1R-ACHE-6a	ACHE	5-HT-receptor-ligand \| Derivative of Donepezil \| Multitarget \| Piperidine \| Sigma1R

Sigma1R-ACHE-6b	ACHE	5-HT-receptor-ligand \| Derivative of Donepezil \| Multitarget \| Piperidine \| Sigma1R

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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