Type Inhibitor

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Type_inhibitor Report for: Insecticide

Insecticides are substances used to kill insects. The main insecticides interacting with alpha/beta hydrolases are carbamates and organophosphates that inhibit acetylcholinesterases or carboxylesterases of insects. Few neonicotinoids or pyrthrinoids target alpha/beta hydrolases

InhibitorMain targeted enzyme familiesTypeStructure
AcephateACHE Insecticide | Organophosphate | Sulfur Compound
AlanycarbACHE Carbamate | Insecticide | Propionate | Sulfur Compound
AldicarbACHE Carbamate | Insecticide | Sulfur Compound
AldoxycarbACHE Carbamate | Insecticide | Sulfur Compound
AminocarbACHE Carbamate | Insecticide
Azinphos-MethylACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
BendiocarbACHE Benzodioxo | Carbamate | Insecticide
BenfuracarbACHE Benzofuran | Carbamate | Insecticide | Propionate | Sulfur Compound
BiscarbofuranACHE Benzofuran | Carbamate | Insecticide | Sulfur Compound
BomylACHE Insecticide | Organophosphate
BromophosACHE Insecticide | Organophosphate | Sulfur Compound
BufencarbACHE Carbamate | Insecticide
ButocarboximACHE Carbamate | Insecticide
ButoxycarboximACHE Carbamate | Insecticide | Sulfur Compound
CadusafosACHE Insecticide | Organophosphate | Sulfur Compound
CarbarylACHE Carbamate | Insecticide
CarbofuranACHE Benzofuran | Carbamate | Insecticide
CarbophenothionACHE Insecticide | Organophosphate | Sulfur Compound
CarbosulfanACHE Benzofuran | Carbamate | Insecticide | Sulfur Compound
ChlorethoxyfosACHE Insecticide | Organophosphate | Sulfur Compound
ChlorfenvinphosACHE Insecticide | Organophosphate
ChlormephosACHE Insecticide | Organophosphate | Sulfur Compound
ChlorphoximACHE Cyanide | Insecticide | Organophosphate | Sulfur Compound
ChlorpyrifosACHE Insecticide | OPIDN-OP | Organophosphate | Organothiophosphate | Sulfur Compound
Chlorpyrifos-methyl-oxonACHE Insecticide | Organophosphate
Chlorpyrifos-oxonACHE | ACPH_Peptidase_S9 Insecticide | Organophosphate
ChlorthionACHE Insecticide | Organophosphate | Sulfur Compound | pNP
CoraloxACHE Anthelmintic | Coumarin | Insecticide | Organophosphate
CosbanACHE Carbamate | Insecticide
CoumaphosACHE Anthelmintic | Coumarin | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
CoumithoateACHE Insecticide | Organophosphate
CronetonACHE | BCHE Carbamate | Insecticide | Sulfur Compound
CrotoxyphosACHE Insecticide | Organophosphate
CruformateACHE Insecticide | Organophosphate | tert-Butyl
CyanophosACHE Cyanide | Insecticide | Organophosphate | Sulfur Compound
CythioateACHE Insecticide | Organophosphate | Sulfur Compound
DialiforACHE Insecticide | Isoindole | Organophosphate | Sulfur Compound
Dialifor-oxonACHE Insecticide | Isoindole | Organophosphate | Sulfur Compound
DiazinonACHE Insecticide | Organophosphate | Organothiophosphate | Pyrimidine | Sulfur Compound
Diazinon-oxonACHE Insecticide | Organophosphate | Pyrimidine
DichlofenthionACHE Insecticide | Organophosphate | Sulfur Compound
DichlorvosACHE | ACPH_Peptidase_S9 Insecticide | Organophosphate
DicrotophosACHE Insecticide | Organophosphate
Diisopropyl-amiton Insecticide | Nerve Agent V-series | Organophosphate
DimefoxACHE Insecticide | Organophosphate
DimethoateACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
DioxacarbACHE Carbamate | Insecticide
DisulfotonACHE Acaricide | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
EPNACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound | pNP
EPN-oxonACHE Insecticide | Organophosphate | pNP
Ethienocarb Carbamate | Cyanide | Insecticide
EthionACHE Acaricide | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
Ethyl-bromophosACHE Insecticide | Organophosphate | Sulfur Compound
EthylchlorthionACHE Insecticide | Organophosphate | Sulfur Compound | pNP
FamphurACHE Insecticide | Organophosphate | Sulfonamide | Sulfur Compound
FenitrothionACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound | pNP
FenobucarbACHE Carbamate | Insecticide
FenoxycarbACHE Carbamate | Insecticide
FenthionACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
Fenthion-oxon Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
FlupyrazofosACHE Insecticide | Organophosphate | Pyrazole | Sulfur Compound
FonofosACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
FormetanateACHE Carbamate | Insecticide
FormothionACHE Insecticide | Organophosphate | Sulfur Compound
FurathiocarbACHE Benzofuran | Carbamate | Insecticide | Sulfur Compound
HeptenophosACHE Insecticide | Organophosphate
Iodofenphos Insecticide | Organophosphate
IsochlorthionACHE Insecticide | Organophosphate | Sulfur Compound | pNP
IsofenphosACHE Benzoate | Insecticide | Organophosphate | Sulfur Compound
IsoprocarbACHE Carbamate | Insecticide
LeptophosACHE Insecticide | OPIDN-OP | Organophosphate | Organothiophosphate | Sulfur Compound
MalaoxonACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
MalathionACHE Acaricide | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
MecarbamACHE Carbamate | Insecticide | Organophosphate | Sulfur Compound
MethamidophosACHE Insecticide | Organophosphate | Sulfur Compound
MethidathionACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound | Thiadiazol
MethiocarbACHE | BCHE | Carb_B_Arthropoda Carbamate | Insecticide | Sulfur Compound
MethomylACHE Carbamate | Insecticide | Sulfur Compound
Methyl-demetonACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
MethylchlorpyrifosACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
MethylparaoxonACHE | Carboxypeptidase_S10 Derivative of Paraoxon | Insecticide | Organophosphate | pNP
MethylparathionACHE Derivative of Paraoxon | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound | pNP
MethyltrithionACHE Insecticide | Organophosphate | Sulfur Compound
MetolcarbACHE Carbamate | Insecticide
MocapACHE Insecticide | Organophosphate | Sulfur Compound
MonocrotophosACHE Insecticide | Organophosphate
NaftalofosACHE Insecticide | Isoquinoline | Organophosphate
NaledACHE | ACPH_Peptidase_S9 Insecticide | Organophosphate
OMPAACHE | BCHE Insecticide | Organophosphate
Paraoxon5_AlphaBeta_hydrolase | A85-EsteraseD-FGH | A85-Mycolyl-transferase | ACHE | Acetyl-esterase_deacetylase | BCHE | Bacterial_lip_FamI.1 | Bacterial_lip_FamI.3 | CarbLipBact_1 | Cutinase | Dienelactone_hydrolase | Hormone-sensitive_lipase_like | Lipase_2 | Lipase_3 | PAF-Acetylhydrolase | Pancreatic_lipase | Plant_carboxylesterase Derivative of Paraoxon | Insecticide | Organophosphate | pNP
ParathionACHE | BCHE Derivative of Paraoxon | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound | pNP
Permethrin Cyclopropane | Insecticide | Not A/B H target | Phenoxyphenyl | Pyrethroid
PhenthoateACHE Insecticide | Organophosphate | Sulfur Compound
PhorateACHE Acaricide | Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
PhosaloneACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
PhosmetACHE Insecticide | Isoindole | Organophosphate | Organothiophosphate | Sulfur Compound
PhosmetoxonACHE Insecticide | Isoindole | Organophosphate | Organothiophosphate | Phthalimido | Sulfur Compound
PhosphamidonACHE Insecticide | Organophosphate
PhoximACHE Cyanide | Insecticide | Organophosphate | Sulfur Compound
PirimicarbACHE Carbamate | Insecticide | Pyrimidine
Pirimiphos-methylACHE Insecticide | Organophosphate | Pyrimidine | Sulfur Compound
ProfenofosACHE | ACPH_Peptidase_S9 Insecticide | Organophosphate | Sulfur Compound
PromecarbACHE Carbamate | Insecticide
PropaphosACHE | BCHE Insecticide | Organophosphate | Sulfur Compound
PropetamphosACHE | BCHE Insecticide | Organophosphate | Sulfur Compound
PropoxurACHE | BCHE Carbamate | Insecticide
ProthiofosACHE Insecticide | Organophosphate | Sulfur Compound
PyraclofosACHE Insecticide | Organophosphate | Pyrazole | Sulfur Compound
PyrazophosACHE Insecticide | Organophosphate | Pyrazole | Sulfur Compound
PyridaphenthionACHE Insecticide | Organophosphate | Pyrazole | Pyridazine | Sulfur Compound
QuinalphosACHE Insecticide | Organophosphate | Quinoxaline | Sulfur Compound
RabonACHE Insecticide | Organophosphate
SulfotepACHE Insecticide | Organophosphate | Sulfur Compound
SulprofosACHE Insecticide | Organophosphate
SystemoxACHE Insecticide | Organophosphate | Sulfur Compound
TebupirimfosACHE | BCHE Insecticide | Organophosphate | Pyrimidine | Sulfur Compound
TemephosACHE Insecticide | Organophosphate | Organothiophosphate | Sulfur Compound
TerbamACHE Carbamate | Insecticide | tert-Butyl
TerbufosACHE Insecticide | Organophosphate | tert-Butyl
ThiometonACHE Insecticide | Organophosphate
TriazamateACHE Carboxamide | Insecticide | Triazol | tert-Butyl
TriazophosACHE Insecticide | Organophosphate | Sulfur Compound | Triazol
Trichlorfon~MetrifonateACHE | ACPH_Peptidase_S9 | BCHE Anthelmintic | Insecticide | Organophosphate
VamidothionACHE Insecticide | Organophosphate
ZectranACHE Carbamate | Insecticide

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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