Gene_Locus Report

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Gene_locus Report for: human-ABHD2

Name Class
human-ABHD2NameHomo sapiens (Human) Monoacylglycerol lipase ABHD2 LABH2 LBH2 protein phps1-2
SpeciesHomo sapiens
Organismman
Gene_nameABHD2
LABH2
BlockX
Familyabh_upf0017
Database (13)
Paper (22)
CommentMonoacylglycerol lipase ABHD2 Enhanced neointimal hyperplasia was observed in Abhd2-deficient mice, using an experimental vascular cuff placement injury model. Abhd2 is expressed in vascular smooth muscle cells (SMCs). An association between the human ABHD2 gene and colorectal cancer and with Risks for Chronic Obstructive Pulmonary Disease is reported. ABHD2 is a steroid-activated (progesterone P4) enzyme that hydrolyzes 2-arachidonoylglycerol. ABHD2 is expressed in sperm and in ovaries
Sequencehuman-ABHD2
Proteinhuman-ABHD2
Peptidehuman-ABHD2
InhibitorCompound-183
Substrate2-Monoolein
2-Arachidonylglycerol
ChemicalProgesterone
Tree_nodeHydrolase_4243224
abh_upf0017314984

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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