Gene_Locus Report

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Gene_locus Report for: human-AADAC

Name Class
human-AADACNameHomo sapiens (Human) arylacetamide deacetylase
SpeciesHomo sapiens
Organismman
Gene_nameAADAC
DAC
BlockH
FamilyArylacetamide_deacetylase
DatabaseSwissProtP22760 AAAD_HUMAN
C9K0E9 C9K0E9_HUMAN
GenbankL32179 HUMARDE
CH471052
AC068647
TremblP22760
C9K0E9
Ncbi_nid537513 1703031
RefSeq_dnaNM_001086
RefSeq_peptideNP_001077
NCBI_TaxID9606
UniGene506908
OMIM600338
EnsemblENSG00000114771
EntrezGene13
PrositePS01173
PS01174
PdocPDOC00903
HUGO17
Paper (14)
CommentArylacetamide deacetylase displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity
Sequencehuman-AADAC
Typecdna
Proteinhuman-AADAC
Peptidehuman-AADAC
InhibitorEpicatechin-gallate
Epigallocatechin-gallate
Vinblastine
Substrate (6)
Tree_nodeArylacetamide_deacetylase76412

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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