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Inhibitor Report for: ZLWH-23

Name Class
ZLWH-23Type (7)
Other_NameHY-144316
CS-0379471
Chemical_Nomenclature1-(cyclopropanecarbonylamino)-N-[2-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]ethyl]-9H-pyrido[3,4-b]indole-7-carboxamide
FormulaC30H32FN5O2
MW513.6
PaperLiu_2021_Eur.J.Med.Chem_229_114095
Commentanti-AChE potency (IC50 = 0.27 microM) and selective BuChE inhibition (IC50 = 20.82 microM), as well as moderate GSK-3 inhibition (IC50 = 6.78 microM)
CID163322222
FamilyACHE
InChIKeyAMLAWNFGPZNOOW-UHFFFAOYSA-N
CanonicalSMILESC1CC1C(=O)NC2=NC=CC3=C2NC4=C3C=CC(=C4)C(=O)NCCC5CCN(CC5)CC6=CC=CC=C6F
InChIInChI=1S/C30H32FN5O2/c31-25-4-2-1-3-22(25)18-36-15-11-19(12-16-36)9-13-33-29(37)21-7-8-23-24-10-14-32-28(27(24)34-26(23)17-21)35-30(38)20-5-6-20/h1-4,7-8,10,14,17,19-20,34H,5-6,9,11-13,15-16,18H2,(H,33,37)(H,32,35,38)

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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