Inhibitor Report for: Tacrine-Donepezil-hybrid3
| Tacrine-Donepezil-hybrid3 | Type | Derivative of Tacrine |
|---|
| | Derivative of Donepezil |
| Other_Name | CHEMBL486901 |
| | Tacrine-E2020 analog 3 |
| | BDBM8979 |
| | N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-(1,2,3,4-tetrahydroacridin-9-ylamino)acetamide |
| Chemical_Nomenclature | N-[2-(1-benzylpiperidin-4-yl)ethyl]-2-(1,2,3,4-tetrahydroacridin-9-ylamino)acetamide |
| Formula | C29H36N4O |
| MW | 456.63 |
| Pick_me_to_call | display_script | Tacrine-Donepezil-hybrid3 |
| Paper | Shao_2004_Bioorg.Med.Chem.Lett_14_4639 |
| Comment | IC50=6.0 nM |
| CID | 10004239 |
| Family | ACHE |
| InChIKey | AYESZVAJFBYQHK-UHFFFAOYSA-N |
| CanonicalSMILES | C1CCC2=NC3=CC=CC=C3C(=C2C1)NCC(=O)NCCC4CCN(CC4)CC5=CC=CC=C5 |
| InChI | InChI=1S/C29H36N4O/c34-28(30-17-14-22-15-18-33(19-16-22)21-23-8-2-1-3-9-23)20-31-29-24-10-4-6-12-26(24)32-27-13-7-5-11-25(27)29/h1-4,6,8-10,12,22H,5,7,11,13-21H2,(H,30,34)(H,31,32) |
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