Inhibitor Report for: Tacrine-Benzofuran
| Tacrine-Benzofuran | Type (6) |
|---|
| Chemical_Nomenclature | N-(1-Benzofuran-2-Ylmethyl)-N'-(1,2,3,4-Tetrahydroacridin-9-Yl)heptane-1,7-Diamine |
| Formula | C29H35N3O |
| MW | 441.60 |
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| Paper | Zha_2016_J.Med.Chem_59_114 |
| Structure | 4W63 |
| Comment | compound able to reduce the hydrolytic activity of AChE, and potentially prevent amyloid production through the inhibition of BACE-1 activity |
| Gene_locus | torca-ACHE |
| CID | 91864546 |
| Family | ACHE |
| InChIKey | LJASCSHXLYLOCF-UHFFFAOYSA-N |
| CanonicalSMILES | C1CCC2=NC3=CC=CC=C3C(=C2C1)NCCCCCCCNCC4=CC5=CC=CC=C5O4 |
| InChI | InChI=1S/C29H35N3O/c1(2-10-18-30-21-23-20-22-12-4-9-17-28(22)33-23)3-11-19-31-29-24-13-5-7-15-26(24)32-27-16-8-6-14-25(27)29/h4-5,7,9,12-13,15,17,20,30H,1-3,6,8,10-11,14,16,18-19,21H2,(H,31,32) |
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