Inhibitor Report for: TADE
| TADE | Type | Derivative of Tacrine |
|---|
| Other_Name (5) |
| Chemical_Nomenclature | N'-(1,2,3,4-tetrahydroacridin-9-yl)ethane-1,2-diamine |
| Formula | C15H19N3 |
| MW | 241.33 |
|  |
| Paper | Meena_2019_Mol.Pharm_16_2296 |
| Comment | The IC50 for AChE and BuChE were 229.1 +/- 1.2 and 59.84 +/- 1.1 nM respectively. Selectivity ratio of 0.261 towards AChE |
| CID | 11658774 |
| Family | ACHE |
| | BCHE |
| InChIKey | MTPGMAOIWNBPSP-UHFFFAOYSA-N |
| CanonicalSMILES | C1CCC2=NC3=CC=CC=C3C(=C2C1)NCCN |
| InChI | InChI=1S/C15H19N3/c16-9-10-17-15-11-5-1-3-7-13(11)18-14-8-4-2-6-12(14)15/h1,3,5,7H,2,4,6,8-10,16H2,(H,17,18) |
|
|
|
