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News Report for: September-29-2021

Name Class
September-29-2021Paper (5)
Structure (9)
Number687
DateSeptember 29, 2021
Comment Bjorkgren et al. published that ABHD2 regulates the rhythm of follicular maturation and estrous stages of the female reproductive cycle (a preprint in BioRxv had been published earlier) Structural basis of gating modulation of Kv4-2 channel complexes by intracellular Kv channel-interacting proteins (KChIP1) and transmembrane dipeptidyl peptidase-related proteins (DPP6) is published by Kise et al.. Electron microscopy structures and X-Ray structures will be available soon (7E8B, 7E87, 7E89, 7E8H, 7E8E, 7E8G) Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties is published by Wichur et al. and structures are available. (7AWI, 7AWH, 7AWG) Novel reversible-binding PET ligands for imaging Monoacylglycerol Lipase based on the piperazinyl azetidine scaffold are published by Rong et al. ABHD16A deficiency causes a complicated form of hereditary spastic paraplegia associated with intellectual disability and cerebral anomalies as published by Lemire et al.

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