Inhibitor Report for: Phthalimido-Galanthaminium-4d
| Phthalimido-Galanthaminium-4d | Type (6) |
|---|
| Other_Name (8) |
| Chemical_Nomenclature | 9-Deydro-10-N-Demethyl-10-N-(8'-phthalimidooctyl)-galanthaminium bromide |
| Formula | C32H37N2O5 |
| MW | 529.27 |
|  |
| Paper | Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| | Mary_1998_Bioorg.Med.Chem_6_1835 |
| Structure | 1W4L |
| Comment | IC50 0.1 +/- 0.02 (10-7 M) more potent than both Galanthamine and Tacrine (Mary et al 1998).Structure of torca-ACHE inhibited Greenblatt_2004 1W4L |
| Gene_locus | torca-ACHE |
| CID | 5288394 |
| Family | ACHE |
| InChIKey | VLGAHTYYCHWLNI-BHRZLAGCSA-N |
| CanonicalSMILES | COC1=C2C3=C(C=C1)C=[N+](CCC34C=CC(CC4O2)O)CCCCCCCCN5C(=O)C6=CC=CC=C6C5=O |
| InChI | InChI=1S/C32H37N2O5/c1-38-26-13-12-22-21-33(19-16-32-15-14-23(35)20-27(32)39-29(26)28(22)32)17-8-4-2-3-5-9-18-34-30(36)24-10-6-7-11-25(24)31(34)37/h6-7,10-15,21,23,27,35H,2-5,8-9,16-20H2,1H3/q+1/t23-,27-,32-/m0/s1 |
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