This entry represents a domain found peptidases Xaa-Pro dipeptidyl-peptidase and glutaryl-7-aminocephalosporanic-acid acylase, which belong to MEROPS peptidase families S15. It is also found in hydrolases from the CocE/NonD family. Cocaine esterase (CocE) hydrolyzes cocaine endowing the bacteria with the ability to utilise cocaine as a sole source of carbon and energy. YcjY-like are bacterial cell division gene and LipSM54-like_FamXVI belongs also to this larger family