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Inhibitor Report for: PIMP
Name
Class
PIMP
Type
Organophosphate
Surrogate OP
Nerve Agent G-series
Derivative of Sarin
Phthalimido
Isoindole
Other_Name
Phthalimidyl isopropyl methylphosphonate
Chemical_Nomenclature
2-[methyl(propan-2-yloxy)phosphoryl]oxyisoindole-1,3-dione
Formula
C12H14NO5P
MW
283.22
Paper
Coban_2016_Toxicol.Lett_248_39
Meek_2012_Toxicol.Sci_126_525
Chambers_2013_Chem.Biol.Interact_203_135
Chambers_2016_Ann.N.Y.Acad.Sci_1374_52
Comment
sarin analogue. Less toxic but giving the same adduct
CID
87411366
Family
ACHE
InChIKey
KVQCPBJKHFOQSK-UHFFFAOYSA-N
CanonicalSMILES
CC(C)OP(=O)(C)ON1C(=O)C2=CC=CC=C2C1=O
InChI
InChI=1S/C12H14NO5P/c1-8(2)17-19(3,16)18-13-11(14)9-6-4-5-7-10(9)12(13)15/h4-8H,1-3H3
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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