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Substrate Report for: PAF-2-Thio

Name Class
PAF-2-ThioTypeTrimethylammonium
Choline ester
Other_Name (5)
Chemical_Nomenclature[(2R)-2-acetylsulfanyl-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
FormulaC26H54NO6PS
CAS_number74389-68-7
96801-55-7
MW539.74
Pick_me_to_calldisplay_scriptPAF-2-Thio
PaperAarsman_1991_Eur.J.Biochem_200_187
Zuliani_2023_Antioxidants.(Basel)_12_597
Stewart_1991_J.Lipid.Mediat_4_299
CommentPAF-2-Thio is a synthetic substrate for lysophospholipase II and for PAF-Acetyl hydrolase. In the Ellman reaction (the free thiol product of reaction is detected colorimetrically with the DTNB reagent)
Gene_locushuman-PLA2G7
CID10347222
FamilyPAF-Acetylhydrolase
LYsophospholipase_carboxylesterase
InChIKeyYPPZOKNKENLFTE-AREMUKBSSA-N
CanonicalSMILESCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)SC(=O)C
InChIInChI=1S/C26H54NO6PS/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(35-25(2)28)24-33-34(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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