Type Inhibitor

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Type_inhibitor Report for: Oxime

Name Class
CommentComponds like RR'C=NOH, where R is an organic side-chain and R' may be hydrogen, forming an aldoxime, or another organic group, forming a ketoxime. Oxime compounds can reactivate OP inhibited cholinesterases by attaching to phosphorus, forming an oxime-phosphonate, which then splits away from the acetylcholinesterase molecule

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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