Type Inhibitor

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Type_inhibitor Report for: NMDA-ligand

Name Class
NMDA-ligandInhibitor (9)
CommentNot an alpha/beta hydrolase target but can be used as a building block for larger inhibitors of enzymes of the family designed as multitarget compoundsNMDA receptor: ionotropic clas of glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner.

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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