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Mutation Report for: N322E/E325G_human-BCHE

Name Class
N322E/E325G_human-BCHEGene_locushuman-BCHE
Torpedo_number324
327
324,327
AA_ChangeN322E/E325G
Mode_of_mutationSite directed mutagenesis
Modification (2)
SummaryCatalysis;Catalytic triad replacement;Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
PaperGrigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138
Commentp.N322E/E325G Asn322Glu/Glu325Gly The original glutamic acid residue of the catlytic triad at position 322 was converted to glycine and a new glutamic acid residue was introduced at position 322 in place of asparagine.

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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