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Inhibitor Report for: N-10-Phenothiazine-1-Naphtyl-carbamate

N-10-Phenothiazine-1-Naphtyl-carbamate	Type	Phenothiazine
		Carbamate
	Other_Name (5)
	Chemical_Nomenclature	naphthalen-1-yl phenothiazine-10-carboxylate
	Formula	C23H15NO2S
	MW	369.4
	Paper	Darvesh_2008_J.Med.Chem_51_4200
		Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822
	Comment	(Compound 28 Darvesh et al. 2008) Ki BCHE 0.036 micro M (for comparison Donepezil 2.21 for BCHE and 0.024 for ACHE), Ka ACHE 1650 M-1min-1 (for comparison rivastigmine 1130 M-1min-1)
	Gene_locus	human-BCHE
	CID	16645664
	Family	BCHE
	InChIKey	BJICBLMMTYZFKB-UHFFFAOYSA-N
	CanonicalSMILES	C1=CC=C2C(=C1)C=CC=C2OC(=O)N3C4=CC=CC=C4SC5=CC=CC=C53
	InChI	InChI=1S/C23H15NO2S/c25-23(26-20-13-7-9-16-8-1-2-10-17(16)20)24-18-11-3-5-14-21(18)27-22-15-6-4-12-19(22)24/h1-15H