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News Report for: MAY-11-2016

Name Class
MAY-11-2016PaperAllgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514
Cox_2016_Bioorg.Med.Chem.Lett_26_2622
Sayer_2016_Sci.Rep_6_25542
Structure5FPP
5FPQ
5ISM
5FRD
Number428
DateMay 11, 2016
Comment Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site is published by Sayer et al. and structure will be available soon (5FRD). Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6 is published by Allgardsson et al. and structures are available (5FPP, 5FPQ).Structure of human DPP4 in complex with a novel 5,5,6-tricyclic pyrrolidine inhibitor is availble (5ISM) and published by Cox et al..

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