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Substrate Report for: Lidocaine

Name Class
LidocaineTypeLocal anesthetic
Drug
Not A/B H target
Other_Name (9)
Chemical_Nomenclature2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
FormulaC14H22N2O
CAS_number137-58-6
MW234.34
PaperHyatt_2007_J.Med.Chem_50_1876
Higuchi_2013_Drug.Metab.Dispos_41_1220
CommentLidocaine is a commonly used local anaesthetic that, besides blocking voltage-dependent Na(+) channels, has multiple inhibitory effects on muscle-type nicotinic acetylcholine (ACh) receptors (nAChRs)
CID3676
FamilyCarboxylesterase
Carb_B_Chordata
InChIKeyNNJVILVZKWQKPM-UHFFFAOYSA-N
CanonicalSMILESCCN(CC)CC(=O)NC1=C(C=CC=C1C)C
InChIInChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
IupharLig2623
WikipediaLidocaine

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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