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Family Report for: Lactobacillus_peptidase

Name Class
Lactobacillus_peptidaseRank2
FamilyPeptidase_S15
Gene_locus (37)
BlockX
LED_DatabaseabH29
PaperRigolet_2002_Structure.(Camb)_10_1383
Ryder_2023_ACS.Omega_8_35410
Structure6NFF
1LNS
EC_number3.4.14.11
InterproIPR000383 X-Pro dipeptidyl-peptidase-like domain Peptidase_S15
CommentLactococcus X-Pro dipeptidyl-peptidase proteins (X-PDAP) belong to the S15 family of the carboxypeptidase (SC) clan. These proteins, which have similar pecificity to mammalian dipeptidyl-peptidase IV, cleave Xaa-Pro-releasing N-terminal dipeptides. The penultimate residue must be proline. In Lactococcus, the proteins exist as cytoplasmic homodimers. The closest relative is Cocaine_esterase
PfamPF02129 Peptidase_S15
PIRSFPIRSF009397 X-Pro dipeptidyl-peptidase
MEROPSS15
InhibitorDFP
PMSF
SubstrateGly-Pro-pNA

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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