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Mutation Report for: G122A_human-ACHE
Name
Class
G122A_human-ACHE
Gene_locus
human-ACHE
Torpedo_number
119
AA_Change
G122A
Mode_of_mutation
Site directed mutagenesis
Modification
Oxyanion hole
Summary
Oxyanion hole;Steric hindrance of acyl pocket;Ordentlich_1998_J.Biol.Chem_273_19509
Paper
Ordentlich_1998_J.Biol.Chem_273_19509
Comment
p.G122A Gly122Ala (p.G153A Gly153Ala in primary sequence with 31 amino-acids signal peptide) Oxyanion hole;Steric hindrance of acyl pocket
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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