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Mutation Report for: G116E_human-BCHE
Name
Class
G116E_human-BCHE
Gene_locus
human-BCHE
Torpedo_number
118
AA_Change
G116E
Mode_of_mutation
Site directed mutagenesis
Modification
Oxyanion hole
Summary
Oxyanion hole;no activity;Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
Paper
Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
Kinetic_parameter
Butyrylthiocholine_G116E_human-BCHE
Comment
p.G116E Gly116Glu (p.G144E Gly144Glu in primary sequence with 28 amino-acids signal peptide) Oxyanion hole; no activity
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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