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News Report for: Febuary-17-2021

Name Class
Structure (9)
DateFebruary 17, 2021
Comment Structural and biochemical insights into the inhibition of human Acetylcholinesterase by G-Series nerve agents and subsequent reactivation by HI-6 are published by McGuire et al., and structures are available (6WVP, 6WVQ, 6WUV, 6WUY, 6WUZ, 6WV1, 6WVC) A single second shell amino acid determines affinity and kinetics of linagliptin binding to type 4 dipeptidyl peptidase and fibroblast activation protein (FAP) is published by Schnapp et al. and structure of human FAPalpha in complex with linagliptin is available (6Y0F) Structure of oligopeptidase B from S. proteomaculans with modified hinge region in complex with N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide is available (7NE7) and will be published soon by Petrenko et al.

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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