News Report for: February-16-2022
| February-16-2022 | Paper | Guercio_2022_Commun.Biol_5_126 |
|---|
| | He_2022_J.Med.Chem_65_2191 |
| | Scheiner_2022_J.Am.Chem.Soc__ |
| | Di Bisceglie_2022_Polymers.(Basel)_14_411 |
| Structure (6) |
| Number | 707 |
| Date | February 16, 2022 |
| Comment |  New Structures of human acetylcholinesterase apo and in complex with tacrine and donepazil are available (7E3D, 7E3I, 7E3H) and will be published soon by Dileep et al.  Guercio et al. published structural and functional analyses which explain Pea KAI2 receptor diversity and reveal stereoselective catalysis during signal perception. Crystal structure of Pisum sativum KAI2 Apo form and in complex with GR24-ent5DS product are available (7K2Z, 7K38) Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging is published by He et al. Crystal structure of human monoglyceride lipase with compound 13, YH149 is available (7PRM) Photoswitchable pseudoirreversible butyrylcholinesterase inhibitors which allow optical control of inhibition in Vitro and enable restoration of cognition in an Alzheimer's Disease mouse model upon irradiation are published by Scheiner et al. Cutinase-catalyzed polyester-polyurethane degradation: elucidation of the hydrolysis mechanism is published by Di Bisceglie et al. |
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