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Mutation Report for: E285A_human-ACHE

Name Class
E285A_human-ACHEGene_locushuman-ACHE
Torpedo_number278
AA_ChangeE285A
Mode_of_mutationSite directed mutagenesis
ModificationPeripheral Anionic Site
SummaryPeripheral Anionic Site;2 to 10 fold increase of inhibition K for PAS ligands;Barak_1994_J.Biol.Chem_269_6296;Shafferman_1994_EMBO.J_13_3448;Shafferman_1995_5th.ChE.Meeting.Madras__189
Paper (3)
Kinetic_parameter (7)
Commentp.E285A Glu285Ala (p.E316A Glu316Ala in primary sequence with 31 amino-acids signal peptide) eripheral Anionic Site;2 to 10 fold increase of inhibition K for PAS ligands

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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