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Inhibitor Report for: Donepezil-derivative-DZ7
Name
Class
Donepezil-derivative-DZ7
Type
Piperidine
Derivative of Donepezil
Inden
Chemical_Nomenclature
(2~{E})-5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{H}-inden-1-one
Formula
C24H27NO3
MW
377.48
Paper
Caliandro_2018_J.Enzyme.Inhib.Med.Chem_33_794
Structure
5NAP
Comment
non-chiral donepezil-like inhibitor 17 compound 1 in the publication
Gene_locus
torca-ACHE
CID
10762160
Family
ACHE
InChIKey
LPMOTUSFDTTWJL-UDWIEESQSA-N
CanonicalSMILES
COc1cc2CC(=C/C3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
InChI
1S/C24H27NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,12,14-15,17H,8-11,13,16H2,1-2H3/b20-12+
Send your questions or comments to :
Mail to:
Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite:
Lenfant 2013 Nucleic.Acids.Res.
or
Marchot Chatonnet 2012 Prot.Pept Lett.
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