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Substrate Report for: Dipivefrin

Dipivefrin	Type	Drug
		Not A/B H target
		Pro-Drug
		Propionate
	Other_Name (5)
	Chemical_Nomenclature	[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate
	Formula	C19H29NO5
	MW	351.43
	Paper	Anderson_1984_Arch.Ophthalmol_102_913
		Mindel_1982_Arch.Ophthalmol_100_147
		Nakamura_1993_Ophthalmic.Res_25_46
		Nakamura_1993_Graefes.Arch.Clin.Exp.Ophthalmol_231_551
	Comment	Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).Dipivefrin is hydrolyzed by cholinesterases and carboxylesterase
	CID	3105
	Family	Carb_B_Chordata
		ACHE
		BCHE
	InChIKey	OCUJLLGVOUDECM-UHFFFAOYSA-N
	CanonicalSMILES	CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C
	InChI	InChI=1S/C19H29NO5/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6/h8-10,13,20-21H,11H2,1-7H3