Type Reactivator

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Type_reactivator Report for: Derivative of Tacrine

Name Class
Derivative of TacrineReactivator7-MEOTA-4-pyridinealdoxime
CommentTacrine is one of the first cholinesterase inhibitor used to treat Alzheimer's disease. The rational for associating a molecule of tacrine with an oxime is to improve the afinity of the compound with cholinesterase and place the reactivtor close to the phosphorylated active site

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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