News Report for: December-14-2022
December-14-2022 | Paper | Zhang_2022_Front.Endocrinol.(Lausanne)_13_1067529 |
| Structure (17) |
| Number | 749 |
| Date | December 14, 2022 |
| Comment | The Molecule of the Month on the PDB server highlights the Click Chemistry discovered by the Sharpless and Mendal laboratories. Synthesis of Acetylcholinesterase inhibitors in the active site was one of the first demonstration of the potentials of this technique. Molecule of the Month Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders are published by Zhang et al. and structures will be soon available (8GS4, 8GS3) Structures of Notum in complex with fragment inhibitors are available (8BSP, 8BSQ, 8BSR, 8BSZ, 8BT0, 8BT2, 8BT5, 8BT7, 8BT8, 8BTA, 8BTC, 8BTE, 8BTH, 8BTI) and will be published soon by Zhao et al. Structure of double cysteine mutations in Geobacillus zalihae T1 lipase is available (7EY3) and will be published soon by Hamdan et al. |
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