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News Report for: DECEMBER-22-2016

Name Class
DECEMBER-22-2016PaperKosak_2016_Sci.Rep_6_39495
Chekan_2016_J.Am.Chem.Soc_138_16452
Woolford_2016_J.Med.Chem_59_10738
Hagstrom_2017_Arch.Toxicol_91_2837
Structure5DYW
5DYT
5DYY
5LYY
5LZ2
5LZ4
5LZ5
5LZ7
5LZ8
5LZ9
5TXE
5TXC
Number457
DateDecember 22, 2016
Comment The 15th International Symposium on Cholinergic Mechanisms took place October 16-20th, 2016, in Marseille, France (XVth ISCM) and was very successful. If you were there, please let us know of your appreciation and send us your pictures! (see the pictures already available at (XVth ISCM images). Development of an in-vivo active reversible butyrylcholinesterase inhibitor is published by Kosak et al. and structures will be available soon (5DYW, 5DYY 5DYT). Structure of the Lasso peptide isopeptidase identifies a topology for processing threaded substrates is published by Chakan et al. and structures are available (5TXE, 5TXC). Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) is published by Woolford et al. and structures are available (5LYY, 5LZ2, 5LZ4, 5LZ5, 5LZ7, 5LZ8, 5LZ9). Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation is published by Hagstrom et al.

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