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Mutation Report for: D74N/W286A_human-ACHE

Name Class
D74N/W286A_human-ACHEGene_locushuman-ACHE
Torpedo_number72,279
279
72
AA_ChangeD74N/W286A
Mode_of_mutationSite directed mutagenesis
ModificationPeripheral Anionic Site
SummaryPeripheral Anionic Site;cooperativity of mutations D74 W286 10+4 increase Ki;Shafferman_1995_5th.ChE.Meeting.Madras__189
PaperShafferman_1995_5th.ChE.Meeting.Madras__189
Commentp.D74N/W286A Asp74Gln/Trp286Ala (p.D105N/W317A Asp105Gln/Trp317Ala in primary sequence with 31 amino-acids signal peptide) Peripheral Anionic Site;cooperativity of mutations D74 W286 10+4 increase Ki

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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