p.D70G/F561Y Asp70Gly/Phe561Tyr (p.D98G/F589Y Asp98Gly/Phe589Tyr in primary sequence with 28 amino-acids signal peptide) The F561Y(F589Y) could be considered as natural but was only found in clones of neuroblastomas and gliostomas, as such are somatic mutations not found in families as abnormal plasma cholinesterases
