Mutation Report for: D134H/R136Q_human-ACHE

D134H/R136Q_human-ACHE	Gene_locus	human-ACHE
	Torpedo_number (3)
	AA_Change	D134H/R136Q
	Mode_of_mutation	Site directed mutagenesis
	Modification	Stability
	Summary	Stability;ACHE:G/C R136Q was introduced to revert effect of natural snp D134H;Valle_2011_J.Pharmacol.Exp.Ther_338_125
	Paper	Valle_2011_J.Pharmacol.Exp.Ther_338_125
	Comment	p.D134H/R136Q Asp134His/Arg136Gln (p.D165H/R167Q Asp165His/Arg167Gln in primary sequence with 31 amino-acids signal peptide) R136Q was introduced to revert effect of natural snp D134H (Valle et al. 2011)

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

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