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Inhibitor Report for: BIMP

Name Class
BIMPTypeDerivative of Sarin
Organophosphate
Surrogate OP
Nerve Agent G-series
Other_NameDiisopropyl dimethylpyrophosphonate
AC1LCHGR
SCHEMBL12705386
Methylphosphonic acid, anhydride, bis(isopropyl) ester
Chemical_Nomenclature2-[methyl-[methyl(propan-2-yloxy)phosphoryl]oxyphosphoryl]oxypropane
FormulaC8H20O5P2
MW258.18
Paper (5)
CommentBIMP has the same phosphonate group as sarin and similar anti-acetylcholinesterase (AChE) activity to that of sarin (IC50 = 3.9 nM in bovine erythrocyte AChE
CID600301
FamilyACHE
BCHE
InChIKeySAVYTRKCUVDEFC-UHFFFAOYSA-N
CanonicalSMILESCC(C)OP(=O)(C)OP(=O)(C)OC(C)C
InChIInChI=1S/C8H20O5P2/c1-7(2)11-14(5,9)13-15(6,10)12-8(3)4/h7-8H,1-6H3

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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