Design and synthesis of novel spiro derivatives as potent and reversible Monoacylglycerol Lipase (MAGL) inhibitors: Bioisosteric transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl moiety is published by Ikeda et al. and structures are available (7L4W, 7L50, 7L4U, 7L4T). Autism spectrum disorder/intellectual disability-associated mutations in Trio disrupt Neuroligin 1-mediated synaptogenesis is published by Tian et al. Computational design and crystal structure of a highly efficient benzoylecgonine hydrolase is published by Chen et al. and structure will be available soon (7F65) EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence as published by Gautheron et al.