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Structure Report for: 7AYR

Name Class
7AYRNameCrystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B115 (replaces 6T6U withdrawn)
Gene_locushuman-DPP8
PaperCarvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498
PDB_file7ayr-pdb
Inhibitor4-Oxo-beta-Lactam-B115
4-Oxo-beta-Lactam-B115-closed
FamilyDPP4N_Peptidase_S9
CommentFehr, L., Carvalho, L.A.R., Ross, B.H., Lum, K., Vieira, A.C., Kiefersauer, R., Geiss-Friedlander, R., Kaiser, M., Rodrigues, T., Lucas, S.D., Cravatt, B.F., Huber, R., Moreira, R.
In the structure the beta-lactam ring is described as open
Revelation_date30-Jun-2021
NewsJune-30-2021

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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