Structure Report for: 7AYQ
7AYQ | Name | Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B114 (replaces 6T6T withdrawn) |
| Gene_locus | human-DPP8 |
| Paper | Carvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498 |
| PDB_file | 7ayq-pdb |
| Inhibitor | 4-Oxo-beta-Lactam-B114 |
| | 4-Oxo-beta-Lactam-B114-closed |
| Family | DPP4N_Peptidase_S9 |
| Comment | Fehr, L., Carvalho, L.A.R., Ross, B.H., Lum, K., Vieira, A.C., Kiefersauer, R., Geiss-Friedlander, R., Kaiser, M., Rodrigues, T., Lucas, S.D., Cravatt, B.F., Huber, R., Moreira, R. |
| | In the structure the beta-lactam ring is described as open |
| Revelation_date | 30-Jun-2021 |
| News | September-14-2022 |
| | June-30-2021 |
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