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Inhibitor Report for: 6FSE-15

6FSE-15	Type	Piperidine
	Other_Name	1-(4-(4-Ethylpiperazin-1-yl)piperidin-1-yl)-2-((4'-methoxy-[1,1'-biphenyl]-4-yl)oxy)ethanone dihydrochloride
		E5K
	Formula	C26H35N3O3
	MW	437.57
	Paper	Knutsson_2018_J.Med.Chem_61_10545
	Structure	6FSE
	Comment	combines a mosquito versus human AChE selectivity with a high potency also for the resistance-conferring mutation G122S (G119S)
	Gene_locus	anoga-ACHE1
	CID	137349228
	Family	ACHE
	InChIKey	HQHBRBVCWLKIRI-UHFFFAOYSA-N
	CanonicalSMILES	CCN1CCN(CC1)C2CCN(CC2)C(=O)COC3=CC=C(C=C3)C4=CC=C(C=C4)OC
	InChI	InChI=1S/C26H35N3O3/c1-3-27-16-18-28(19-17-27)23-12-14-29(15-13-23)26(30)20-32-25-10-6-22(7-11-25)21-4-8-24(31-2)9-5-21/h4-11,23H,3,12-20H2,1-2H3